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Protein

Cytochrome c oxidase subunit 3

Gene

ctaE

Organism
Paracoccus denitrificans
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Oxidase aa(3) subunit 3
Gene namesi
Name:ctaE
Synonyms:coiII
OrganismiParacoccus denitrificans
Taxonomic identifieri266 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeParacoccus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini2 – 15CytoplasmicAdd BLAST14
Transmembranei16 – 36HelicalAdd BLAST21
Topological domaini37 – 48PeriplasmicAdd BLAST12
Transmembranei49 – 77HelicalAdd BLAST29
Topological domaini78 – 79Cytoplasmic2
Transmembranei80 – 115HelicalAdd BLAST36
Topological domaini116 – 139PeriplasmicAdd BLAST24
Transmembranei140 – 166HelicalAdd BLAST27
Topological domaini167 – 168Cytoplasmic2
Transmembranei169 – 197HelicalAdd BLAST29
Topological domaini198 – 203Periplasmic6
Transmembranei204 – 237HelicalAdd BLAST34
Topological domaini238 – 244Cytoplasmic7
Transmembranei245 – 274HelicalAdd BLAST30

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001838862 – 274Cytochrome c oxidase subunit 3Add BLAST273

Structurei

Secondary structure

1274
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP06030
SMRiP06030
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP06030

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107QS1 Bacteria
COG1845 LUCA

Family and domain databases

CDDicd01665 Cyt_c_Oxidase_III, 1 hit
Gene3Di1.20.120.80, 1 hit
InterProiView protein in InterPro
IPR024791 Cyt_c/ubiquinol_Oxase_su3
IPR033945 Cyt_c_oxase_su3_dom
IPR000298 Cyt_c_oxidase-like_su3
IPR035973 Cyt_c_oxidase_su3-like_sf
IPR013833 Cyt_c_oxidase_su3_a-hlx
PANTHERiPTHR11403 PTHR11403, 1 hit
PfamiView protein in Pfam
PF00510 COX3, 1 hit
SUPFAMiSSF81452 SSF81452, 1 hit
PROSITEiView protein in PROSITE
PS50253 COX3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P06030-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAHVKNHDYQ ILPPSIWPFF GAIGAFVMLT GAVAWMKGIT FFGLPVEGPW
60 70 80 90 100
MFLIGLVGVL YVMFGWWADV VNEGETGEHT PVVRIGLQYG FILFIMSEVM
110 120 130 140 150
FFVAWFWAFI KNALYPMGPD SPIKDGVWPP EGIVTFDPWH LPLINTLILL
160 170 180 190 200
LSGVAVTWAH HAFVLEGDRK TTINGLIVAV ILGVCFTGLQ AYEYSHAAFG
210 220 230 240 250
LADTVYAGAF YMATGFHGAH VIIGTIFLFV CLIRLLKGQM TQKQHVGFEA
260 270
AAWYWHFVDV VWLFLFVVIY IWGR
Length:274
Mass (Da):30,786
Last modified:January 23, 2007 - v3
Checksum:i082F95AF9AD4A27B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X04406 Genomic DNA Translation: CAA27995.1
X05828 Genomic DNA Translation: CAA29272.1
PIRiS03807

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X04406 Genomic DNA Translation: CAA27995.1
X05828 Genomic DNA Translation: CAA29272.1
PIRiS03807

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1QLEX-ray3.00C2-274[»]
ProteinModelPortaliP06030
SMRiP06030
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4107QS1 Bacteria
COG1845 LUCA

Miscellaneous databases

EvolutionaryTraceiP06030

Family and domain databases

CDDicd01665 Cyt_c_Oxidase_III, 1 hit
Gene3Di1.20.120.80, 1 hit
InterProiView protein in InterPro
IPR024791 Cyt_c/ubiquinol_Oxase_su3
IPR033945 Cyt_c_oxase_su3_dom
IPR000298 Cyt_c_oxidase-like_su3
IPR035973 Cyt_c_oxidase_su3-like_sf
IPR013833 Cyt_c_oxidase_su3_a-hlx
PANTHERiPTHR11403 PTHR11403, 1 hit
PfamiView protein in Pfam
PF00510 COX3, 1 hit
SUPFAMiSSF81452 SSF81452, 1 hit
PROSITEiView protein in PROSITE
PS50253 COX3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCOX3_PARDE
AccessioniPrimary (citable) accession number: P06030
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: January 23, 2007
Last modified: October 25, 2017
This is version 108 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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Main funding by: National Institutes of Health

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