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UniProtKB - P05413 (FABPH_HUMAN)

Entry version 201 (02 Jun 2021)
Sequence version 4 (23 Jan 2007)
Previous versions | rss
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Protein

Fatty acid-binding protein, heart

Gene

FABP3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei127Fatty acid1
Binding sitei129Fatty acid1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransport
LigandLipid-binding

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P05413

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-163560, Triglyceride catabolism

Chemistry databases

SwissLipids knowledge resource for lipid biology

More...SwissLipidsi		SLP:000001521

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Fatty acid-binding protein, heart
Alternative name(s):
Fatty acid-binding protein 3
Heart-type fatty acid-binding protein
Short name:
H-FABP
Mammary-derived growth inhibitor
Short name:
MDGI
Muscle fatty acid-binding protein
Short name:
M-FABP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FABP3
Synonyms:FABP11, MDGI
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:3557, FABP3

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		134651, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P05413

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000121769.7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		2170

Open Targets

More...OpenTargetsi		ENSG00000121769

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA27958

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P05413, Tchem

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL3344

Drug and drug target database

More...DrugBanki		DB04224, Oleic Acid
DB03796, Palmitic Acid
DB03193, Stearic acid

DrugCentral

More...DrugCentrali		P05413

IUPHAR/BPS Guide to PHARMACOLOGY

More...GuidetoPHARMACOLOGYi		2533

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		FABP3

Domain mapping of disease mutations (DMDM)

More...DMDMi		119802

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources2 Publications
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000673212 – 133Fatty acid-binding protein, heartAdd BLAST132

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylvalineCombined sources1
Modified residuei8PhosphothreonineBy similarity1
Modified residuei20Phosphotyrosine; by Tyr-kinasesBy similarity1
Modified residuei23PhosphoserineBy similarity1
Modified residuei30PhosphothreonineBy similarity1
Modified residuei83PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P05413

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P05413

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P05413

MaxQB - The MaxQuant DataBase

More...MaxQBi		P05413

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P05413

PeptideAtlas

More...PeptideAtlasi		P05413

PRoteomics IDEntifications database

More...PRIDEi		P05413

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		12633
51837

2D gel databases

REPRODUCTION-2DPAGE

More...REPRODUCTION-2DPAGEi		IPI00219684

University College Dublin 2-DE Proteome Database

More...UCD-2DPAGEi		P05413

PTM databases

CarbonylDB database of protein carbonylation sites

More...CarbonylDBi		P05413

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P05413

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P05413

SwissPalm database of S-palmitoylation events

More...SwissPalmi		P05413

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000121769, Expressed in heart left ventricle and 205 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P05413, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P05413, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000121769, Group enriched (heart muscle, skeletal muscle)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		108468, 28 interactors

Protein interaction database and analysis system

More...IntActi		P05413, 13 interactors

Molecular INTeraction database

More...MINTi		P05413

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000362817

Chemistry databases

BindingDB database of measured binding affinities

More...BindingDBi		P05413

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P05413, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1133
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P05413

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P05413

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4015, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155104

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P05413

Identification of Orthologs from Complete Genome Data

More...OMAi		THGSVVC

Database of Orthologous Groups

More...OrthoDBi		1417203at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P05413

TreeFam database of animal gene trees

More...TreeFami		TF316894

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.40.128.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR012674, Calycin
IPR000463, Fatty_acid-bd
IPR031259, ILBP
IPR000566, Lipocln_cytosolic_FA-bd_dom

The PANTHER Classification System

More...PANTHERi		PTHR11955, PTHR11955, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00061, Lipocalin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00178, FATTYACIDBP

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50814, SSF50814, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00214, FABP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

P05413-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVDAFLGTWK LVDSKNFDDY MKSLGVGFAT RQVASMTKPT TIIEKNGDIL 
        60         70         80         90        100
TLKTHSTFKN TEISFKLGVE FDETTADDRK VKSIVTLDGG KLVHLQKWDG 
       110        120        130 
QETTLVRELI DGKLILTLTH GTAVCTRTYE KEA
Length:133
Mass (Da):14,858
Last modified:January 23, 2007 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5FD396B1BE538A3C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
S4R371S4R371_HUMAN
Fatty acid-binding protein, heart
FABP3
132Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R3A2S4R3A2_HUMAN
Fatty acid-binding protein, heart
FABP3
89Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti2V → A in CAA71305 (Ref. 2) Curated1
Sequence conflicti105L → K AA sequence (PubMed:3421901).Curated1
Sequence conflicti125C → S AA sequence (PubMed:3421901).Curated1
Sequence conflicti130E → Q AA sequence (PubMed:2266954).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_06116553K → R. Corresponds to variant dbSNP:rs2228194Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X56549 mRNA Translation: CAA39889.1
Y10255 mRNA Translation: CAA71305.1
U57623 Genomic DNA Translation: AAB02555.1
AK314122 mRNA Translation: BAG36813.1
U17081 Genomic DNA Translation: AAC99800.1
S67314 mRNA Translation: AAB29294.1
BT006727 mRNA Translation: AAP35373.1
AL451070 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX07619.1
BC007021 mRNA Translation: AAH07021.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS342.1

Protein sequence database of the Protein Information Resource

More...PIRi		S15432, FZHUC

NCBI Reference Sequences

More...RefSeqi		NP_004093.1, NM_004102.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000373713; ENSP00000362817; ENSG00000121769

Database of genes from NCBI RefSeq genomes

More...GeneIDi		2170

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:2170

UCSC genome browser

More...UCSCi		uc001bss.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56549 mRNA Translation: CAA39889.1
Y10255 mRNA Translation: CAA71305.1
U57623 Genomic DNA Translation: AAB02555.1
AK314122 mRNA Translation: BAG36813.1
U17081 Genomic DNA Translation: AAC99800.1
S67314 mRNA Translation: AAB29294.1
BT006727 mRNA Translation: AAP35373.1
AL451070 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX07619.1
BC007021 mRNA Translation: AAH07021.1
CCDSiCCDS342.1
PIRiS15432, FZHUC
RefSeqiNP_004093.1, NM_004102.4

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1G5WNMR-A2-133[»]
1HMRX-ray1.40A2-133[»]
1HMSX-ray1.40A2-133[»]
1HMTX-ray1.40A2-133[»]
2HMBX-ray2.10A2-133[»]
3RSWX-ray2.60A/B1-133[»]
3WBGX-ray2.15A/B/C/D1-133[»]
3WVMX-ray0.88A1-133[»]
3WXQX-ray1.60A1-133[»]
4TJZX-ray0.87A1-133[»]
4TKBX-ray0.86A1-133[»]
4TKHX-ray0.93A1-133[»]
4TKJX-ray0.87A1-133[»]
4WBKX-ray1.37A1-133[»]
5B27X-ray1.02A1-133[»]
5B28X-ray0.90A1-133[»]
5B29X-ray1.28A2-133[»]
5CE4Other0.98A1-132[»]
5HZ9X-ray2.30A/B/C/D/E/F/G/H1-133[»]
6AQ1X-ray1.40A/B1-133[»]
SMRiP05413
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi108468, 28 interactors
IntActiP05413, 13 interactors
MINTiP05413
STRINGi9606.ENSP00000362817

Chemistry databases

BindingDBiP05413
ChEMBLiCHEMBL3344
DrugBankiDB04224, Oleic Acid
DB03796, Palmitic Acid
DB03193, Stearic acid
DrugCentraliP05413
GuidetoPHARMACOLOGYi2533
SwissLipidsiSLP:000001521

PTM databases

CarbonylDBiP05413
iPTMnetiP05413
PhosphoSitePlusiP05413
SwissPalmiP05413

Genetic variation databases

BioMutaiFABP3
DMDMi119802

2D gel databases

REPRODUCTION-2DPAGEiIPI00219684
UCD-2DPAGEiP05413

Proteomic databases

EPDiP05413
jPOSTiP05413
MassIVEiP05413
MaxQBiP05413
PaxDbiP05413
PeptideAtlasiP05413
PRIDEiP05413
ProteomicsDBi12633
51837

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		4505, 1135 antibodies

The DNASU plasmid repository

More...DNASUi		2170

Genome annotation databases

EnsembliENST00000373713; ENSP00000362817; ENSG00000121769
GeneIDi2170
KEGGihsa:2170
UCSCiuc001bss.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		2170
DisGeNETi2170

GeneCards: human genes, protein and diseases

More...GeneCardsi		FABP3
HGNCiHGNC:3557, FABP3
HPAiENSG00000121769, Group enriched (heart muscle, skeletal muscle)
MIMi134651, gene
neXtProtiNX_P05413
OpenTargetsiENSG00000121769
PharmGKBiPA27958
VEuPathDBiHostDB:ENSG00000121769.7

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4015, Eukaryota
GeneTreeiENSGT00940000155104
InParanoidiP05413
OMAiTHGSVVC
OrthoDBi1417203at2759
PhylomeDBiP05413
TreeFamiTF316894

Enzyme and pathway databases

PathwayCommonsiP05413
ReactomeiR-HSA-163560, Triglyceride catabolism

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		2170, 7 hits in 978 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		FABP3, human
EvolutionaryTraceiP05413

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		Heart-type_fatty_acid_binding_protein

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		2170
PharosiP05413, Tchem

Protein Ontology

More...PROi		PR:P05413
RNActiP05413, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000121769, Expressed in heart left ventricle and 205 other tissues
ExpressionAtlasiP05413, baseline and differential
GenevisibleiP05413, HS

Family and domain databases

Gene3Di2.40.128.20, 1 hit
InterProiView protein in InterPro
IPR012674, Calycin
IPR000463, Fatty_acid-bd
IPR031259, ILBP
IPR000566, Lipocln_cytosolic_FA-bd_dom
PANTHERiPTHR11955, PTHR11955, 1 hit
PfamiView protein in Pfam
PF00061, Lipocalin, 1 hit
PRINTSiPR00178, FATTYACIDBP
SUPFAMiSSF50814, SSF50814, 1 hit
PROSITEiView protein in PROSITE
PS00214, FABP, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFABPH_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P05413
Secondary accession number(s): B2RAB6, Q5VV93, Q99957
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: January 23, 2007
Last modified: June 2, 2021
This is version 201 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families
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