RPLP0

Functionⁱ

Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

GO - Molecular functionⁱ

large ribosomal subunit rRNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
RNA binding
Source: UniProtKB
Inferred from high throughput direct assayⁱ
- 22658674
- 22681889
structural constituent of ribosome
Source: GO_Central
Inferred from direct assayⁱ
- 3323886

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cytoplasmic translation
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
interleukin-12-mediated signaling pathway Source: Reactome
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Source: Reactome
ribosomal large subunit assembly
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
SRP-dependent cotranslational protein targeting to membrane Source: Reactome
translation
Source: UniProtKB
Non-traceable author statementⁱ
- 12962325
translational initiation Source: Reactome

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Ribonucleoprotein, Ribosomal protein

Molecular function

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactomeⁱ	R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156902 Peptide chain elongation R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane R-HSA-192823 Viral mRNA Translation R-HSA-2408557 Selenocysteine synthesis R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-72689 Formation of a pool of free 40S subunits R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72764 Eukaryotic Translation Termination R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-9010553 Regulation of expression of SLITs and ROBOs R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Reactomeⁱ

R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: 60S acidic ribosomal protein P0 Alternative name(s): 60S ribosomal protein L10E Large ribosomal subunit protein uL101 Publication
Gene namesⁱ	Name:RPLP0
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 12

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000089157.15
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:10371 RPLP0
MIMⁱ	180510 gene
neXtProtⁱ	NX_P05388

Keywords - Cellular componentⁱ

Cytoplasm, Nucleus

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	6175
Open Targets More...OpenTargetsⁱ	ENSG00000089157
PharmGKBⁱ	PA34772

Polymorphism and mutation databases

BioMutaⁱ	RPLP0
DMDMⁱ	133041

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000154758	1 – 317	60S acidic ribosomal protein P0Add BLAST		317

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	24	PhosphotyrosineBy similarity	1
Modified residueⁱ	59	PhosphothreonineCombined sources	1
Cross-linkⁱ	297	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateCombined sources
Cross-linkⁱ	297	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residueⁱ	304	PhosphoserineCombined sources	1
Modified residueⁱ	307	PhosphoserineCombined sources	1

Keywords - PTMⁱ

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDⁱ	P05388
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P05388
PaxDbⁱ	P05388
PeptideAtlas More...PeptideAtlasⁱ	P05388
PRIDEⁱ	P05388
ProteomicsDBⁱ	51833
TopDownProteomicsⁱ	P05388-1 [P05388-1]

2D gel databases

REPRODUCTION-2DPAGE More...REPRODUCTION-2DPAGEⁱ	P05388

REPRODUCTION-2DPAGEⁱ

P05388

PTM databases

iPTMnetⁱ	P05388
PhosphoSitePlusⁱ	P05388
SwissPalmⁱ	P05388

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000089157 Expressed in 88 organ(s), highest expression level in left adrenal gland
CleanExⁱ	HS_RPLP0
ExpressionAtlasⁱ	P05388 baseline and differential
Genevisibleⁱ	P05388 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA003512

HPAⁱ

HPA003512

Interactionⁱ

Subunit structureⁱ

P0 forms a pentameric complex by interaction with dimers of P1 and P2 (PubMed:3323886). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs (PubMed:17289661). Interacts with APEX1 (PubMed:19188445). Interacts with FMR1 isoform 6 (PubMed:24658146).4 Publications

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
CCNDBP1	O95273	3	EBI-354101,EBI-748961
STAU1	O95793	4	EBI-354101,EBI-358174

Protein-protein interaction databases

BioGridⁱ	112094, 219 interactors
CORUMⁱ	P05388
IntActⁱ	P05388, 56 interactors
Molecular INTeraction database More...MINTⁱ	P05388
STRINGⁱ	9606.ENSP00000339027

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P05388
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the universal ribosomal protein uL10 family.Curated

Phylogenomic databases

eggNOGⁱ	KOG0815 Eukaryota COG0244 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000017839
HOGENOMⁱ	HOG000210987
HOVERGENⁱ	HBG000711
InParanoidⁱ	P05388
KEGG Orthology (KO) More...KOⁱ	K02941
OMAⁱ	MAHVAEW
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0F47
PhylomeDBⁱ	P05388
TreeFamⁱ	TF300849

Family and domain databases

InterProⁱ	View protein in InterPro IPR030670 L10E_eukaryotes IPR001790 Ribosomal_L10P
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00466 Ribosomal_L10, 1 hit
PIRSFⁱ	PIRSF039087 L10E, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 12 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: P05388-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MPREDRATWK SNYFLKIIQL LDDYPKCFIV GADNVGSKQM QQIRMSLRGK 
        60         70         80         90        100
AVVLMGKNTM MRKAIRGHLE NNPALEKLLP HIRGNVGFVF TKEDLTEIRD 
       110        120        130        140        150
MLLANKVPAA ARAGAIAPCE VTVPAQNTGL GPEKTSFFQA LGITTKISRG 
       160        170        180        190        200
TIEILSDVQL IKTGDKVGAS EATLLNMLNI SPFSFGLVIQ QVFDNGSIYN 
       210        220        230        240        250
PEVLDITEET LHSRFLEGVR NVASVCLQIG YPTVASVPHS IINGYKRVLA 
       260        270        280        290        300
LSVETDYTFP LAEKVKAFLA DPSAFVAAAP VAAATTAAPA AAAAPAKVEA 
       310 
KEESEESDED MGFGLFD

Length:317

Mass (Da):34,274

Last modified:November 1, 1988 - v1

Checksum:ⁱ255AD25571C51199

GO

Isoform 2 (identifier: P05388-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
156-217: Missing.

« Hide

        10         20         30         40         50
MPREDRATWK SNYFLKIIQL LDDYPKCFIV GADNVGSKQM QQIRMSLRGK 
        60         70         80         90        100
AVVLMGKNTM MRKAIRGHLE NNPALEKLLP HIRGNVGFVF TKEDLTEIRD 
       110        120        130        140        150
MLLANKVPAA ARAGAIAPCE VTVPAQNTGL GPEKTSFFQA LGITTKISRG 
       160        170        180        190        200
TIEILGVRNV ASVCLQIGYP TVASVPHSII NGYKRVLALS VETDYTFPLA 
       210        220        230        240        250
EKVKAFLADP SAFVAAAPVA AATTAAPAAA AAPAKVEAKE ESEESDEDMG 

FGLFD

Note: No experimental confirmation available.

Show »

Length:255

Mass (Da):27,436

Checksum:ⁱB10D4073AAA5990A

GO

Computationally mapped potential isoform sequencesⁱ

There are 12 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name	Protein names	Gene names	Length	Annotation

	F8VWS0	F8VWS0_HUMAN	60S acidic ribosomal protein P0 60S acidic ribosomal protein P0	RPLP0	281	Annotation score:
	F8VPE8	F8VPE8_HUMAN	60S acidic ribosomal protein P0 60S acidic ribosomal protein P0	RPLP0	153	Annotation score:
	F8VWV4	F8VWV4_HUMAN	60S acidic ribosomal protein P0 60S acidic ribosomal protein P0	RPLP0	111	Annotation score:
	F8VW21	F8VW21_HUMAN	60S acidic ribosomal protein P0 60S acidic ribosomal protein P0	RPLP0	244	Annotation score:
	F8VU65	F8VU65_HUMAN	60S acidic ribosomal protein P0 60S acidic ribosomal protein P0	RPLP0	247	Annotation score:
	F8VS58	F8VS58_HUMAN	60S acidic ribosomal protein P0 60S acidic ribosomal protein P0	RPLP0	121	Annotation score:
	F8VRK7	F8VRK7_HUMAN	60S acidic ribosomal protein P0 60S acidic ribosomal protein P0	RPLP0	156	Annotation score:
	F8VZS0	F8VZS0_HUMAN	60S acidic ribosomal protein P0 60S acidic ribosomal protein P0	RPLP0	246	Annotation score:
	F8VQY6	F8VQY6_HUMAN	60S acidic ribosomal protein P0 60S acidic ribosomal protein P0	RPLP0	142	Annotation score:
	G3V210	G3V210_HUMAN	60S acidic ribosomal protein P0 60S acidic ribosomal protein P0 (Ribosomal protein, large, P0, isoform CRA_c)	RPLP0 hCG_2016152	166	Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	246	K → E in AAH01127 (PubMed:15489334).Curated		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_055867	156 – 217	Missing in isoform 2. 1 PublicationAdd BLAST		62

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M17885 mRNA Translation: AAA36470.1 AC004263 Genomic DNA Translation: AAC05176.1 BC000087 mRNA Translation: AAH00087.1 BC000345 mRNA Translation: AAH00345.1 BC000752 mRNA Translation: AAH00752.1 BC001127 mRNA Translation: AAH01127.1 BC001834 mRNA Translation: AAH01834.1 BC003655 mRNA Translation: AAH03655.1 BC005863 mRNA Translation: AAH05863.1 BC008092 mRNA Translation: AAH08092.1 BC008594 mRNA Translation: AAH08594.1 BC009867 mRNA Translation: AAH09867.1 BC015173 mRNA Translation: AAH15173.1 BC015690 mRNA Translation: AAH15690.1 BC107717 mRNA Translation: AAI07718.1 AB007187 Genomic DNA Translation: BAA25845.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS9193.1 [P05388-1]
PIRⁱ	A27125 R5HUP0
NCBI Reference Sequences More...RefSeqⁱ	NP_000993.1, NM_001002.3 [P05388-1] NP_444505.1, NM_053275.3 [P05388-1]
UniGeneⁱ	Hs.546285

Genome annotation databases

Ensemblⁱ	ENST00000228306; ENSP00000339027; ENSG00000089157 [P05388-1] ENST00000313104; ENSP00000366471; ENSG00000089157 [P05388-2] ENST00000392514; ENSP00000376299; ENSG00000089157 [P05388-1] ENST00000551150; ENSP00000449328; ENSG00000089157 [P05388-1]
GeneIDⁱ	6175
KEGGⁱ	hsa:6175
UCSC genome browser More...UCSCⁱ	uc001txp.4 human [P05388-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P05388	60S acidic ribosomal protein P0		HUMAN		317	UniRef100_P05388
60S acidic ribosomal protein P0		PANTR		317
60S acidic ribosomal protein P0		PONAB		317
60S acidic ribosomal protein P0		PANPA		317
60S acidic ribosomal protein P0		NOMLE		317
+2
P05388-2	RPLP0 isoform 11		PANTR		255	UniRef100_A0A2I3TRK3
RPLP0 isoform 11		PONAB		255
Uncharacterized protein		FELCA		255
Uncharacterized protein		PANPA		255
Uncharacterized protein		NOMLE		255
+1

Protein	Similar proteins		Species	Score	Length	Source
P05388	60S acidic ribosomal protein P0	)	PIG		318	UniRef90_P05388
60S acidic ribosomal protein P0		BOVIN		318
60S acidic ribosomal protein P0-like		HUMAN		317
60S acidic ribosomal protein P0		MOUSE		317
60S acidic ribosomal protein P0		RAT		317
+183
P05388-2	Uncharacterized protein		MACMU		256	UniRef90_F6WUA2
Uncharacterized protein		COLAP		256
Uncharacterized protein		MANLE		256
Uncharacterized protein		MACFA		256
Uncharacterized protein		RHIBE		256
+25

Protein	Similar proteins		Species	Score	Length	Source
P05388	60S acidic ribosomal protein P0		BOVIN		318	UniRef50_P05388
60S acidic ribosomal protein P0	)	PIG		318
60S acidic ribosomal protein P0-like		HUMAN		317
60S acidic ribosomal protein P0		MOUSE		317
60S acidic ribosomal protein P0		RAT		317
+184
P05388-2	Uncharacterized protein		MACMU		253	UniRef50_F7GDL0
Uncharacterized protein		AOTNA		255
60S acidic ribosomal protein P0-like isoform X3		LIPVE		258
Uncharacterized protein		CERAT		256
Uncharacterized protein		COLAP		256
+34

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M17885 mRNA Translation: AAA36470.1 AC004263 Genomic DNA Translation: AAC05176.1 BC000087 mRNA Translation: AAH00087.1 BC000345 mRNA Translation: AAH00345.1 BC000752 mRNA Translation: AAH00752.1 BC001127 mRNA Translation: AAH01127.1 BC001834 mRNA Translation: AAH01834.1 BC003655 mRNA Translation: AAH03655.1 BC005863 mRNA Translation: AAH05863.1 BC008092 mRNA Translation: AAH08092.1 BC008594 mRNA Translation: AAH08594.1 BC009867 mRNA Translation: AAH09867.1 BC015173 mRNA Translation: AAH15173.1 BC015690 mRNA Translation: AAH15690.1 BC107717 mRNA Translation: AAI07718.1 AB007187 Genomic DNA Translation: BAA25845.1
CCDSⁱ	CCDS9193.1 [P05388-1]
PIRⁱ	A27125 R5HUP0
RefSeqⁱ	NP_000993.1, NM_001002.3 [P05388-1] NP_444505.1, NM_053275.3 [P05388-1]
UniGeneⁱ	Hs.546285

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	4V6W	electron microscopy	6.00	q	5-227	[»]
	4V6X	electron microscopy	5.00	Cq	1-317	[»]
	5AJ0	electron microscopy	3.50	AK	1-317	[»]
ProteinModelPortalⁱ	P05388
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	112094, 219 interactors
CORUMⁱ	P05388
IntActⁱ	P05388, 56 interactors
MINTⁱ	P05388
STRINGⁱ	9606.ENSP00000339027

PTM databases

iPTMnetⁱ	P05388
PhosphoSitePlusⁱ	P05388
SwissPalmⁱ	P05388

Polymorphism and mutation databases

BioMutaⁱ	RPLP0
DMDMⁱ	133041

2D gel databases

REPRODUCTION-2DPAGEⁱ	P05388

REPRODUCTION-2DPAGEⁱ

P05388

Proteomic databases

EPDⁱ	P05388
MaxQBⁱ	P05388
PaxDbⁱ	P05388
PeptideAtlasⁱ	P05388
PRIDEⁱ	P05388
ProteomicsDBⁱ	51833
TopDownProteomicsⁱ	P05388-1 [P05388-1]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	6175
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000228306; ENSP00000339027; ENSG00000089157 [P05388-1] ENST00000313104; ENSP00000366471; ENSG00000089157 [P05388-2] ENST00000392514; ENSP00000376299; ENSG00000089157 [P05388-1] ENST00000551150; ENSP00000449328; ENSG00000089157 [P05388-1]
GeneIDⁱ	6175
KEGGⁱ	hsa:6175
UCSCⁱ	uc001txp.4 human [P05388-1]

Organism-specific databases

CTDⁱ	6175
DisGeNETⁱ	6175
EuPathDBⁱ	HostDB:ENSG00000089157.15
GeneCardsⁱ	RPLP0
HGNCⁱ	HGNC:10371 RPLP0
HPAⁱ	HPA003512
MIMⁱ	180510 gene
neXtProtⁱ	NX_P05388
OpenTargetsⁱ	ENSG00000089157
PharmGKBⁱ	PA34772
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0815 Eukaryota COG0244 LUCA
GeneTreeⁱ	ENSGT00390000017839
HOGENOMⁱ	HOG000210987
HOVERGENⁱ	HBG000711
InParanoidⁱ	P05388
KOⁱ	K02941
OMAⁱ	MAHVAEW
OrthoDBⁱ	EOG091G0F47
PhylomeDBⁱ	P05388
TreeFamⁱ	TF300849

Enzyme and pathway databases

Reactomeⁱ	R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156902 Peptide chain elongation R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane R-HSA-192823 Viral mRNA Translation R-HSA-2408557 Selenocysteine synthesis R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-72689 Formation of a pool of free 40S subunits R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72764 Eukaryotic Translation Termination R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-9010553 Regulation of expression of SLITs and ROBOs R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Reactomeⁱ

R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

ChiTaRSⁱ	RPLP0 human
GeneWikiⁱ	RPLP0
GenomeRNAiⁱ	6175
Protein Ontology More...PROⁱ	PR:P05388
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000089157 Expressed in 88 organ(s), highest expression level in left adrenal gland
CleanExⁱ	HS_RPLP0
ExpressionAtlasⁱ	P05388 baseline and differential
Genevisibleⁱ	P05388 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR030670 L10E_eukaryotes IPR001790 Ribosomal_L10P
Pfamⁱ	View protein in Pfam PF00466 Ribosomal_L10, 1 hit
PIRSFⁱ	PIRSF039087 L10E, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RLA0_HUMAN
Accessionⁱ	P05388Primary (citable) accession number: P05388 Secondary accession number(s): Q3B7A4, Q9BVK4
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 1, 1988
	Last sequence update:	November 1, 1988
	Last modified:	November 7, 2018
	This is version 208 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Ribosomal proteins
Ribosomal proteins families and list of entries
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
Human chromosome 12
Human chromosome 12: entries, gene names and cross-references to MIM

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P05388 (RLA0_HUMAN)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

60S acidic ribosomal protein P0

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Other locations

Cytosol

Endoplasmic reticulum

Extracellular region or secreted

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

2D gel databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

2D gel databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ