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Entry version 197 (08 May 2019)
Sequence version 2 (01 Nov 1995)
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Protein

Heterochromatin protein 1

Gene

Su(var)205

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression.2 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei24Histone H3K9me21
Binding sitei45Histone H3K9me21
Binding sitei48Histone H3K9me21

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-73772 RNA Polymerase I Promoter Escape
R-DME-8953750 Transcriptional Regulation by E2F6
R-DME-983231 Factors involved in megakaryocyte development and platelet production

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
P05205

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Heterochromatin protein 1
Short name:
HP1
Alternative name(s):
Non-histone chromosomal protein C1A9 antigen
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Su(var)205
Synonyms:HP1
ORF Names:CG8409
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0003607 Su(var)205

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi26V → M: Impairs chromo domain folding and histone H3 binding. Does not affect piwi binding. 2 Publications1
Mutagenesisi191I → E: Abolishes piwi binding. 1 Publication1
Mutagenesisi200W → A: Abolishes piwi binding. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000801971 – 206Heterochromatin protein 1Add BLAST206

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei11Phosphoserine1 Publication1
Modified residuei15Phosphoserine2 Publications1
Modified residuei102Phosphoserine1 Publication1
Modified residuei103Phosphoserine1 Publication1
Modified residuei113Phosphoserine1 Publication1
Modified residuei127Phosphothreonine1 Publication1
Modified residuei128Phosphothreonine2 Publications1
Modified residuei134Phosphothreonine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P05205

PRoteomics IDEntifications database

More...
PRIDEi
P05205

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P05205

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0003607 Expressed in 43 organ(s), highest expression level in embryo

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P05205 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer; probably associates with Su(var)3-9. Interacts with Mcm10. Interacts (via chromoshadow domain) with piwi (via N-terminal region).3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
60248, 117 interactors

Database of interacting proteins

More...
DIPi
DIP-21869N

The Eukaryotic Linear Motif resource for Functional Sites in Proteins

More...
ELMi
P05205

Protein interaction database and analysis system

More...
IntActi
P05205, 31 interactors

Molecular INTeraction database

More...
MINTi
P05205

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0079251

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1206
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1KNAX-ray2.10A17-76[»]
1KNEX-ray2.40A17-76[»]
1Q3LX-ray1.64A17-76[»]
3P7JX-ray2.30A/B131-206[»]
6ASZX-ray1.52A17-76[»]
6AT0X-ray1.28A17-76[»]

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P05205

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P05205

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini24 – 82Chromo 1PROSITE-ProRule annotationAdd BLAST59
Domaini147 – 205Chromo 2PROSITE-ProRule annotationAdd BLAST59

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni95 – 206Binds to Su(var)39Add BLAST112

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi18 – 23Poly-Glu6

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1911 Eukaryota
ENOG4111JKD LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154152

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P05205

KEGG Orthology (KO)

More...
KOi
K11587

Identification of Orthologs from Complete Genome Data

More...
OMAi
QDTIPVS

Database of Orthologous Groups

More...
OrthoDBi
1628171at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P05205

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00024 CHROMO, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016197 Chromo-like_dom_sf
IPR000953 Chromo/chromo_shadow_dom
IPR017984 Chromo_dom_subgr
IPR023780 Chromo_domain
IPR008251 Chromo_shadow_dom
IPR023779 Chromodomain_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00385 Chromo, 1 hit
PF01393 Chromo_shadow, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00504 CHROMODOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00298 CHROMO, 2 hits
SM00300 ChSh, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54160 SSF54160, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00598 CHROMO_1, 1 hit
PS50013 CHROMO_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P05205-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKKIDNPES SAKVSDAEEE EEEYAVEKII DRRVRKGKVE YYLKWKGYPE
60 70 80 90 100
TENTWEPENN LDCQDLIQQY EASRKDEEKS AASKKDRPSS SAKAKETQGR
110 120 130 140 150
ASSSTSTASK RKSEEPTAPS GNKSKRTTDA EQDTIPVSGS TGFDRGLEAE
160 170 180 190 200
KILGASDNNG RLTFLIQFKG VDQAEMVPSS VANEKIPRMV IHFYEERLSW

YSDNED
Length:206
Mass (Da):23,185
Last modified:November 1, 1995 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6A5B204C487526B7
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti105T → A in strain: NC322, NC358 and NC359. 1 Publication1
Natural varianti126R → C in strain: NC390. 1 Publication1
Natural varianti134T → S in strain: MW25. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M57574 Genomic DNA Translation: AAA28620.1
M14131 mRNA Translation: AAA28402.1 Sequence problems.
FJ218607 Genomic DNA Translation: ACI96755.1
FJ218612 Genomic DNA Translation: ACI96760.1
FJ218613 Genomic DNA Translation: ACI96761.1
FJ218614 Genomic DNA Translation: ACI96762.1
FJ218615 Genomic DNA Translation: ACI96763.1
FJ218616 Genomic DNA Translation: ACI96764.1
FJ218617 Genomic DNA Translation: ACI96765.1
FJ218618 Genomic DNA Translation: ACI96766.1
FJ218619 Genomic DNA Translation: ACI96767.1
FJ218620 Genomic DNA Translation: ACI96768.1
FJ218621 Genomic DNA Translation: ACI96769.1
FJ218622 Genomic DNA Translation: ACI96770.1
FJ218623 Genomic DNA Translation: ACI96771.1
FJ218624 Genomic DNA Translation: ACI96772.1
FJ218625 Genomic DNA Translation: ACI96773.1
FJ218626 Genomic DNA Translation: ACI96774.1
FJ218627 Genomic DNA Translation: ACI96775.1
FJ218628 Genomic DNA Translation: ACI96776.1
FJ218629 Genomic DNA Translation: ACI96777.1
FJ218630 Genomic DNA Translation: ACI96778.1
FJ218631 Genomic DNA Translation: ACI96779.1
FJ218632 Genomic DNA Translation: ACI96780.1
FJ218633 Genomic DNA Translation: ACI96781.1
FJ218634 Genomic DNA Translation: ACI96782.1
FJ218635 Genomic DNA Translation: ACI96783.1
FJ218636 Genomic DNA Translation: ACI96784.1
FJ218637 Genomic DNA Translation: ACI96785.1
FJ218638 Genomic DNA Translation: ACI96786.1
FJ218639 Genomic DNA Translation: ACI96787.1
AE014134 Genomic DNA Translation: AAF52618.1
AE014134 Genomic DNA Translation: AAN11156.1
AY061119 mRNA Translation: AAL28667.1

Protein sequence database of the Protein Information Resource

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PIRi
A39268

NCBI Reference Sequences

More...
RefSeqi
NP_476755.1, NM_057407.4
NP_723361.1, NM_164799.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0079635; FBpp0079251; FBgn0003607
FBtr0079636; FBpp0079252; FBgn0003607

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
34119

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG8409

UCSC genome browser

More...
UCSCi
CG8409-RB d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M57574 Genomic DNA Translation: AAA28620.1
M14131 mRNA Translation: AAA28402.1 Sequence problems.
FJ218607 Genomic DNA Translation: ACI96755.1
FJ218612 Genomic DNA Translation: ACI96760.1
FJ218613 Genomic DNA Translation: ACI96761.1
FJ218614 Genomic DNA Translation: ACI96762.1
FJ218615 Genomic DNA Translation: ACI96763.1
FJ218616 Genomic DNA Translation: ACI96764.1
FJ218617 Genomic DNA Translation: ACI96765.1
FJ218618 Genomic DNA Translation: ACI96766.1
FJ218619 Genomic DNA Translation: ACI96767.1
FJ218620 Genomic DNA Translation: ACI96768.1
FJ218621 Genomic DNA Translation: ACI96769.1
FJ218622 Genomic DNA Translation: ACI96770.1
FJ218623 Genomic DNA Translation: ACI96771.1
FJ218624 Genomic DNA Translation: ACI96772.1
FJ218625 Genomic DNA Translation: ACI96773.1
FJ218626 Genomic DNA Translation: ACI96774.1
FJ218627 Genomic DNA Translation: ACI96775.1
FJ218628 Genomic DNA Translation: ACI96776.1
FJ218629 Genomic DNA Translation: ACI96777.1
FJ218630 Genomic DNA Translation: ACI96778.1
FJ218631 Genomic DNA Translation: ACI96779.1
FJ218632 Genomic DNA Translation: ACI96780.1
FJ218633 Genomic DNA Translation: ACI96781.1
FJ218634 Genomic DNA Translation: ACI96782.1
FJ218635 Genomic DNA Translation: ACI96783.1
FJ218636 Genomic DNA Translation: ACI96784.1
FJ218637 Genomic DNA Translation: ACI96785.1
FJ218638 Genomic DNA Translation: ACI96786.1
FJ218639 Genomic DNA Translation: ACI96787.1
AE014134 Genomic DNA Translation: AAF52618.1
AE014134 Genomic DNA Translation: AAN11156.1
AY061119 mRNA Translation: AAL28667.1
PIRiA39268
RefSeqiNP_476755.1, NM_057407.4
NP_723361.1, NM_164799.2

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1KNAX-ray2.10A17-76[»]
1KNEX-ray2.40A17-76[»]
1Q3LX-ray1.64A17-76[»]
3P7JX-ray2.30A/B131-206[»]
6ASZX-ray1.52A17-76[»]
6AT0X-ray1.28A17-76[»]
SMRiP05205
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi60248, 117 interactors
DIPiDIP-21869N
ELMiP05205
IntActiP05205, 31 interactors
MINTiP05205
STRINGi7227.FBpp0079251

PTM databases

iPTMnetiP05205

Proteomic databases

PaxDbiP05205
PRIDEiP05205

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0079635; FBpp0079251; FBgn0003607
FBtr0079636; FBpp0079252; FBgn0003607
GeneIDi34119
KEGGidme:Dmel_CG8409
UCSCiCG8409-RB d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
34119
FlyBaseiFBgn0003607 Su(var)205

Phylogenomic databases

eggNOGiKOG1911 Eukaryota
ENOG4111JKD LUCA
GeneTreeiENSGT00940000154152
InParanoidiP05205
KOiK11587
OMAiQDTIPVS
OrthoDBi1628171at2759
PhylomeDBiP05205

Enzyme and pathway databases

ReactomeiR-DME-73772 RNA Polymerase I Promoter Escape
R-DME-8953750 Transcriptional Regulation by E2F6
R-DME-983231 Factors involved in megakaryocyte development and platelet production
SignaLinkiP05205

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Su(var)205 fly
EvolutionaryTraceiP05205

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
34119

Protein Ontology

More...
PROi
PR:P05205

Gene expression databases

BgeeiFBgn0003607 Expressed in 43 organ(s), highest expression level in embryo
GenevisibleiP05205 DM

Family and domain databases

CDDicd00024 CHROMO, 1 hit
InterProiView protein in InterPro
IPR016197 Chromo-like_dom_sf
IPR000953 Chromo/chromo_shadow_dom
IPR017984 Chromo_dom_subgr
IPR023780 Chromo_domain
IPR008251 Chromo_shadow_dom
IPR023779 Chromodomain_CS
PfamiView protein in Pfam
PF00385 Chromo, 1 hit
PF01393 Chromo_shadow, 1 hit
PRINTSiPR00504 CHROMODOMAIN
SMARTiView protein in SMART
SM00298 CHROMO, 2 hits
SM00300 ChSh, 1 hit
SUPFAMiSSF54160 SSF54160, 2 hits
PROSITEiView protein in PROSITE
PS00598 CHROMO_1, 1 hit
PS50013 CHROMO_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiHP1_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P05205
Secondary accession number(s): A4V0F1
, B6UVR4, B6UVS1, B6UVS2, B6UVS3, B6UVT2, B6UVT6, B6UVT7, Q9VLR6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: November 1, 1995
Last modified: May 8, 2019
This is version 197 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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