UniProtKB - P05167 (ALEU_HORVU)
Protein
Thiol protease aleurain
Gene
N/A
Organism
Hordeum vulgare (Barley)
Status
Functioni
Catalytic activityi
- Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving Arg-|-Xaa bonds) as well as an endopeptidase. EC:3.4.22.16
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 168 | By similarity | 1 | |
Active sitei | 308 | By similarity | 1 | |
Active sitei | 328 | By similarity | 1 |
GO - Molecular functioni
- cysteine-type endopeptidase activity Source: UniProtKB-EC
Keywordsi
Molecular function | Hydrolase, Protease, Thiol protease |
Biological process | Germination |
Protein family/group databases
MEROPSi | I29.003 |
Names & Taxonomyi
Protein namesi | |
Organismi | Hordeum vulgare (Barley) |
Taxonomic identifieri | 4513 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Pooideae › Triticodae › Triticeae › Hordeinae › Hordeum |
Subcellular locationi
Vacuole
Note: Vacuole-like subcellular compartment.
Vacuole
- vacuole Source: UniProtKB-SubCell
Keywords - Cellular componenti
VacuolePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 22 | Sequence analysisAdd BLAST | 22 | |
PropeptideiPRO_0000026416 | 23 – 143 | Activation peptideSequence analysisAdd BLAST | 121 | |
ChainiPRO_0000026417 | 144 – 362 | Thiol protease aleurainAdd BLAST | 219 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 165 ↔ 208 | By similarity | ||
Glycosylationi | 188 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 199 ↔ 241 | By similarity | ||
Glycosylationi | 257 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 299 ↔ 349 | By similarity |
Keywords - PTMi
Disulfide bond, Glycoprotein, ZymogenProteomic databases
PRIDEi | P05167 |
Expressioni
Inductioni
Aleurain is synthesized by the aleurone cells stimulated by gibberellic or abscisic acid.
Gene expression databases
ExpressionAtlasi | P05167, baseline and differential |
Family & Domainsi
Sequence similaritiesi
Belongs to the peptidase C1 family.PROSITE-ProRule annotation
Keywords - Domaini
SignalFamily and domain databases
CDDi | cd02248, Peptidase_C1A, 1 hit |
InterProi | View protein in InterPro IPR038765, Papain-like_cys_pep_sf IPR025661, Pept_asp_AS IPR000169, Pept_cys_AS IPR025660, Pept_his_AS IPR000668, Peptidase_C1A_C IPR039417, Peptidase_C1A_papain-like IPR013201, Prot_inhib_I29 |
Pfami | View protein in Pfam PF08246, Inhibitor_I29, 1 hit PF00112, Peptidase_C1, 1 hit |
PRINTSi | PR00705, PAPAIN |
SMARTi | View protein in SMART SM00848, Inhibitor_I29, 1 hit SM00645, Pept_C1, 1 hit |
SUPFAMi | SSF54001, SSF54001, 1 hit |
PROSITEi | View protein in PROSITE PS00640, THIOL_PROTEASE_ASN, 1 hit PS00139, THIOL_PROTEASE_CYS, 1 hit PS00639, THIOL_PROTEASE_HIS, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P05167-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAHARVLLLA LAVLATAAVA VASSSSFADS NPIRPVTDRA ASTLESAVLG
60 70 80 90 100
ALGRTRHALR FARFAVRYGK SYESAAEVRR RFRIFSESLE EVRSTNRKGL
110 120 130 140 150
PYRLGINRFS DMSWEEFQAT RLGAAQTCSA TLAGNHLMRD AAALPETKDW
160 170 180 190 200
REDGIVSPVK NQAHCGSCWT FSTTGALEAA YTQATGKNIS LSEQQLVDCA
210 220 230 240 250
GGFNNFGCNG GLPSQAFEYI KYNGGIDTEE SYPYKGVNGV CHYKAENAAV
260 270 280 290 300
QVLDSVNITL NAEDELKNAV GLVRPVSVAF QVIDGFRQYK SGVYTSDHCG
310 320 330 340 350
TTPDDVNHAV LAVGYGVENG VPYWLIKNSW GADWGDNGYF KMEMGKNMCA
360
IATCASYPVV AA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X05167 Genomic DNA Translation: CAA28804.1 |
PIRi | A25492, KHBH |
Genome annotation databases
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X05167 Genomic DNA Translation: CAA28804.1 |
PIRi | A25492, KHBH |
3D structure databases
SMRi | P05167 |
ModBasei | Search... |
Protein family/group databases
MEROPSi | I29.003 |
Proteomic databases
PRIDEi | P05167 |
Genome annotation databases
Gene expression databases
ExpressionAtlasi | P05167, baseline and differential |
Family and domain databases
CDDi | cd02248, Peptidase_C1A, 1 hit |
InterProi | View protein in InterPro IPR038765, Papain-like_cys_pep_sf IPR025661, Pept_asp_AS IPR000169, Pept_cys_AS IPR025660, Pept_his_AS IPR000668, Peptidase_C1A_C IPR039417, Peptidase_C1A_papain-like IPR013201, Prot_inhib_I29 |
Pfami | View protein in Pfam PF08246, Inhibitor_I29, 1 hit PF00112, Peptidase_C1, 1 hit |
PRINTSi | PR00705, PAPAIN |
SMARTi | View protein in SMART SM00848, Inhibitor_I29, 1 hit SM00645, Pept_C1, 1 hit |
SUPFAMi | SSF54001, SSF54001, 1 hit |
PROSITEi | View protein in PROSITE PS00640, THIOL_PROTEASE_ASN, 1 hit PS00139, THIOL_PROTEASE_CYS, 1 hit PS00639, THIOL_PROTEASE_HIS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ALEU_HORVU | |
Accessioni | P05167Primary (citable) accession number: P05167 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 13, 1987 |
Last sequence update: | August 13, 1987 | |
Last modified: | December 2, 2020 | |
This is version 109 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Documents
- SIMILARITY comments
Index of protein domains and families - Peptidase families
Classification of peptidase families and list of entries