Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Elastin

Gene

ELN

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Elastin
Alternative name(s):
Tropoelastin
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ELN
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBos taurus (Bovine)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9913 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000009136 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Extracellular matrix, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 26By similarityAdd BLAST26
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000002116127 – 747ElastinAdd BLAST721

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei344-hydroxyprolineBy similarity1
Modified residuei654-hydroxyprolineBy similarity1
Modified residuei874-hydroxyprolineBy similarity1
Modified residuei105Allysine1 Publication1
Modified residuei109Allysine1 Publication1
Modified residuei1654-hydroxyprolineBy similarity1
Modified residuei1784-hydroxyprolineBy similarity1
Modified residuei1814-hydroxyprolineBy similarity1
Modified residuei188HydroxyprolineBy similarity1
Modified residuei2014-hydroxyprolineBy similarity1
Modified residuei252Allysine1 Publication1
Modified residuei271Allysine1 Publication1
Modified residuei275Allysine1 Publication1
Modified residuei2984-hydroxyprolineBy similarity1
Modified residuei3024-hydroxyprolineBy similarity1
Modified residuei324Allysine1 Publication1
Modified residuei327Allysine1 Publication1
Modified residuei3354-hydroxyprolineBy similarity1
Modified residuei3654-hydroxyprolineBy similarity1
Modified residuei3704-hydroxyprolineBy similarity1
Modified residuei3754-hydroxyprolineBy similarity1
Modified residuei3804-hydroxyprolineBy similarity1
Modified residuei3854-hydroxyprolineBy similarity1
Modified residuei400Allysine1 Publication1
Modified residuei404Allysine1 Publication1
Modified residuei407Allysine1 Publication1
Modified residuei445Allysine1 Publication1
Modified residuei448Allysine1 Publication1
Modified residuei4624-hydroxyprolineBy similarity1
Modified residuei4784-hydroxyprolineBy similarity1
Modified residuei489Allysine1 Publication1
Modified residuei493Allysine1 Publication1
Modified residuei5134-hydroxyprolineBy similarity1
Modified residuei544Allysine1 Publication1
Modified residuei548Allysine1 Publication1
Modified residuei552Allysine1 Publication1
Modified residuei5664-hydroxyprolineBy similarity1
Modified residuei5754-hydroxyprolineBy similarity1
Modified residuei5844-hydroxyprolineBy similarity1
Modified residuei5934-hydroxyprolineBy similarity1
Modified residuei5994-hydroxyprolineBy similarity1
Modified residuei606Allysine1 Publication1
Modified residuei609Allysine1 Publication1
Modified residuei6304-hydroxyprolineBy similarity1
Modified residuei645Allysine1 Publication1
Modified residuei649Allysine1 Publication1
Modified residuei685Allysine1 Publication1
Modified residuei688Allysine1 Publication1
Modified residuei7194-hydroxyprolineBy similarity1
Modified residuei7334-hydroxyprolineBy similarity1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi737 ↔ 7421 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Elastin is formed through the cross-linking of its soluble precursor tropoelastin. Cross-linking is initiated through the action of lysyl oxidase on exposed lysines to form allysine. Subsequent spontaneous condensation reactions with other allysine or unmodified lysine residues result in various bi-, tri-, and tetrafunctional cross-links. The most abundant cross-links in mature elastin fibers are lysinonorleucine, allysine aldol, desmosine, and isodesmosine.
Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.By similarity

Keywords - PTMi

Disulfide bond, Hydroxylation

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
P04985

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

The polymeric elastin chains are cross-linked together into an extensible 3D network. Forms a ternary complex with BGN and MFAP2. Interacts with MFAP2 via divalent cations (calcium > magnesium > manganese) in a dose-dependent and saturating manner (PubMed:11723132). Interacts with FBLN5 and FBN1. Forms a ternary complex with FBN1 and FBLN2 or FBLN5 (By similarity). Interacts with MFAP4 in a Ca (2+)-dependent manner; this interaction promotes ELN self-assembly (PubMed:26601954).By similarity2 Publications

Protein-protein interaction databases

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
P04985

Database of interacting proteins

More...
DIPi
DIP-35453N

Protein interaction database and analysis system

More...
IntActi
P04985, 4 interactors

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the elastin family.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P04985

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003979 Tropoelastin

The PANTHER Classification System

More...
PANTHERi
PTHR24018 PTHR24018, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01500 TROPOELASTIN

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (7)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 7 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: P04985-1) [UniParc]FASTAAdd to basket
Also known as: A

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRSLTAAARR PEVLLLLLCI LQPSQPGGVP GAVPGGVPGG VFFPGAGLGG
60 70 80 90 100
LGVGGLGPGV KPAKPGVGGL VGPGLGAEGS ALPGAFPGGF FGAGGGAAGA
110 120 130 140 150
AAAYKAAAKA GAAGLGVGGI GGVGGLGVST GAVVPQLGAG VGAGVKPGKV
160 170 180 190 200
PGVGLPGVYP GGVLPGAGAR FPGIGVLPGV PTGAGVKPKA QVGAGAFAGI
210 220 230 240 250
PGVGPFGGQQ PGLPLGYPIK APKLPAGYGL PYKTGKLPYG FGPGGVAGSA
260 270 280 290 300
GKAGYPTGTG VGPQAAAAAA KAAAKLGAGG AGVLPGVGVG GPGIPGAPGA
310 320 330 340 350
IPGIGGIAGV GAPDAAAAAA AAAKAAKFGA AGGLPGVGVP GVGVPGVGVP
360 370 380 390 400
GVGVPGVGVP GVGVPGVGVP GVGVPGVGVP GVGVPGVGVP GALSPAATAK
410 420 430 440 450
AAAKAAKFGA RGAVGIGGIP TFGLGPGGFP GIGDAAAAPA AAAAKAAKIG
460 470 480 490 500
AGGVGALGGV VPGAPGAIPG LPGVGGVPGV GIPAAAAAKA AAKAAQFGLG
510 520 530 540 550
PGVGVAPGVG VVPGVGVVPG VGVAPGIGLG PGGVIGAGVP AAAKSAAKAA
560 570 580 590 600
AKAQFRAAAG LPAGVPGLGV GAGVPGLGVG AGVPGLGVGA GVPGPGAVPG
610 620 630 640 650
TLAAAKAAKF GPGGVGALGG VGDLGGAGIP GGVAGVVPAA AAAAKAAAKA
660 670 680 690 700
AQFGLGGVGG LGVGGLGAVP GAVGLGGVSP AAAAKAAKFG AAGLGGVLGA
710 720 730 740
GQPFPIGGGA GGLGVGGKPP KPFGGALGAL GFPGGACLGK SCGRKRK
Length:747
Mass (Da):64,229
Last modified:August 13, 1987 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i633C03E411643D83
GO
Isoform 2 (identifier: P04985-2) [UniParc]FASTAAdd to basket
Also known as: B

The sequence of this isoform differs from the canonical sequence as follows:
     226-239: Missing.

Show »
Length:733
Mass (Da):62,719
Checksum:i80632AC1522BE148
GO
Isoform 3 (identifier: P04985-3) [UniParc]FASTAAdd to basket
Also known as: C

The sequence of this isoform differs from the canonical sequence as follows:
     226-259: Missing.

Show »
Length:713
Mass (Da):61,028
Checksum:i0544AAD9E999FC98
GO
Isoform 4 (identifier: P04985-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     708-708: G → GVAARPGFGLSPIFPG

Show »
Length:762
Mass (Da):65,697
Checksum:iD54BB492D60EDBEE
GO
Isoform 5 (identifier: P04985-5) [UniParc]FASTAAdd to basket
Also known as: Elastin-cBEL2

The sequence of this isoform differs from the canonical sequence as follows:
     598-610: Missing.

Show »
Length:734
Mass (Da):63,003
Checksum:i97CAD6B881E3AC43
GO
Isoform 6 (identifier: P04985-6) [UniParc]FASTAAdd to basket
Also known as: Elastin-cBEL3

The sequence of this isoform differs from the canonical sequence as follows:
     226-259: Missing.
     499-499: L → LALLAFAGL

Show »
Length:721
Mass (Da):61,785
Checksum:i15C6786E94469984
GO
Isoform 7 (identifier: P04985-7) [UniParc]FASTAAdd to basket
Also known as: Elastin-cBEL1

The sequence of this isoform differs from the canonical sequence as follows:
     226-259: Missing.
     654-676: Missing.
     708-708: G → GVAARPGFGLSPIFPG

Show »
Length:705
Mass (Da):60,723
Checksum:iD52D3EC4EFF2D5F3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1 – 3MRS → MAG (PubMed:2543440).Curated3
Sequence conflicti1 – 3MRS → MAG (PubMed:2031719).Curated3
Sequence conflicti12E → G (PubMed:2543440).Curated1
Sequence conflicti12E → G (PubMed:2031719).Curated1
Sequence conflicti78 – 80EGS → GLG (PubMed:2992576).Curated3
Sequence conflicti78 – 80EGS → GLG (PubMed:3665402).Curated3
Sequence conflicti89 – 97GFFGAGGGA → ALVPGGP (PubMed:2992576).Curated9
Sequence conflicti89 – 97GFFGAGGGA → ALVPGGP (PubMed:3665402).Curated9
Sequence conflicti191 – 194QVGA → PGGG (PubMed:2992576).Curated4
Sequence conflicti191 – 194QVGA → PGGG (PubMed:3665402).Curated4
Sequence conflicti213L → V (PubMed:2992576).Curated1
Sequence conflicti213L → V (PubMed:3665402).Curated1
Sequence conflicti292P → A (PubMed:2992576).Curated1
Sequence conflicti292P → A (PubMed:3665402).Curated1
Sequence conflicti334L → F (PubMed:2992576).Curated1
Sequence conflicti334L → F (PubMed:3665402).Curated1
Sequence conflicti393L → V (PubMed:2992576).Curated1
Sequence conflicti393L → V (PubMed:3665402).Curated1
Sequence conflicti398T → A (PubMed:2992576).Curated1
Sequence conflicti398T → A (PubMed:3665402).Curated1
Sequence conflicti413A → G (PubMed:2992576).Curated1
Sequence conflicti413A → G (PubMed:3665402).Curated1
Sequence conflicti424L → V (PubMed:2992576).Curated1
Sequence conflicti424L → V (PubMed:3665402).Curated1
Sequence conflicti439P → Q (PubMed:2992576).Curated1
Sequence conflicti439P → Q (PubMed:3665402).Curated1
Sequence conflicti460V → L (PubMed:2992576).Curated1
Sequence conflicti460V → L (PubMed:3665402).Curated1
Sequence conflicti471L → V (PubMed:2992576).Curated1
Sequence conflicti471L → V (PubMed:3665402).Curated1
Sequence conflicti572A → V (PubMed:2992576).Curated1
Sequence conflicti572A → V (PubMed:3665402).Curated1
Sequence conflicti581A → V (PubMed:2992576).Curated1
Sequence conflicti581A → V (PubMed:3665402).Curated1
Sequence conflicti595P → F (PubMed:2992576).Curated1
Sequence conflicti595P → F (PubMed:3665402).Curated1
Sequence conflicti637V → G (PubMed:2992576).Curated1
Sequence conflicti637V → G (PubMed:3665402).Curated1
Sequence conflicti681Missing (PubMed:6150137).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_004240226 – 259Missing in isoform 3, isoform 6 and isoform 7. CuratedAdd BLAST34
Alternative sequenceiVSP_004239226 – 239Missing in isoform 2. CuratedAdd BLAST14
Alternative sequenceiVSP_011940499L → LALLAFAGL in isoform 6. Curated1
Alternative sequenceiVSP_011941598 – 610Missing in isoform 5. CuratedAdd BLAST13
Alternative sequenceiVSP_011942654 – 676Missing in isoform 7. CuratedAdd BLAST23
Alternative sequenceiVSP_011943708G → GVAARPGFGLSPIFPG in isoform 4 and isoform 7. Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
J02717 mRNA Translation: AAA30503.1
K03505 mRNA Translation: AAA30505.1
K03506 mRNA Translation: AAA30506.1
J02855 Genomic DNA Translation: AAA30776.1
M58652 Genomic DNA Translation: AAA03519.2
M19372
, M11422, M19366, M19367, M19368, M19369, M19370, M19371, M22771, M22772, M22773, M22774, M22775, M22988, M23010 Genomic DNA Translation: AAA30498.1
M19372
, M11422, M19366, M19368, M19369, M19370, M19371, M22771, M22772, M22773, M22774, M22775, M22988, M23010 Genomic DNA Translation: AAA30499.1
M19372
, M11422, M19366, M19367, M19368, M19369, M19370, M19371, M22771, M22772, M22773, M22774, M22988 Genomic DNA Translation: AAA30500.1
M19372
, M11422, M19366, M19367, M19368, M19369, M19370, M19371, M22771, M22772, M22773, M22774, M22775, M22988 Genomic DNA Translation: AAA30501.1
M31898
, M31894, M31895, M31896, M31897 Genomic DNA Translation: AAA96417.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A31865 EABO

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Bt.5361

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J02717 mRNA Translation: AAA30503.1
K03505 mRNA Translation: AAA30505.1
K03506 mRNA Translation: AAA30506.1
J02855 Genomic DNA Translation: AAA30776.1
M58652 Genomic DNA Translation: AAA03519.2
M19372
, M11422, M19366, M19367, M19368, M19369, M19370, M19371, M22771, M22772, M22773, M22774, M22775, M22988, M23010 Genomic DNA Translation: AAA30498.1
M19372
, M11422, M19366, M19368, M19369, M19370, M19371, M22771, M22772, M22773, M22774, M22775, M22988, M23010 Genomic DNA Translation: AAA30499.1
M19372
, M11422, M19366, M19367, M19368, M19369, M19370, M19371, M22771, M22772, M22773, M22774, M22988 Genomic DNA Translation: AAA30500.1
M19372
, M11422, M19366, M19367, M19368, M19369, M19370, M19371, M22771, M22772, M22773, M22774, M22775, M22988 Genomic DNA Translation: AAA30501.1
M31898
, M31894, M31895, M31896, M31897 Genomic DNA Translation: AAA96417.1
PIRiA31865 EABO
UniGeneiBt.5361

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protein-protein interaction databases

CORUMiP04985
DIPiDIP-35453N
IntActiP04985, 4 interactors

Proteomic databases

PRIDEiP04985

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

InParanoidiP04985

Family and domain databases

InterProiView protein in InterPro
IPR003979 Tropoelastin
PANTHERiPTHR24018 PTHR24018, 3 hits
PRINTSiPR01500 TROPOELASTIN

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiELN_BOVIN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P04985
Secondary accession number(s): P04986
, P04987, Q28096, Q28097, Q28098, Q28099, Q28101, Q29421
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: August 13, 1987
Last modified: July 18, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again