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Protein

Cytochrome P450 1A1

Gene

CYP1A1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Catalytic activityi

RH + [reduced NADPH--hemoprotein reductase] + O2 = ROH + [oxidized NADPH--hemoprotein reductase] + H2O.

Cofactori

heme1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei224Substrate1 Publication1
Metal bindingi457Iron (heme axial ligand)1 Publication1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMonooxygenase, Oxidoreductase
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-HSA-1989781 PPARA activates gene expression
R-HSA-211981 Xenobiotics
R-HSA-2142670 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
R-HSA-2142816 Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
R-HSA-9018681 Biosynthesis of protectins
SABIO-RKiP04798
SIGNORiP04798

Chemistry databases

SwissLipidsiSLP:000001329

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome P450 1A1 (EC:1.14.14.1)
Alternative name(s):
CYPIA1
Cytochrome P450 form 6
Cytochrome P450-C
Cytochrome P450-P1
Gene namesi
Name:CYP1A1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000140465.13
HGNCiHGNC:2595 CYP1A1
MIMi108330 gene
neXtProtiNX_P04798

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane, Microsome

Pathology & Biotechi

Organism-specific databases

DisGeNETi1543
OpenTargetsiENSG00000140465
PharmGKBiPA27092

Chemistry databases

ChEMBLiCHEMBL2231
DrugBankiDB02342 2-Methoxyestradiol
DB00316 Acetaminophen
DB00518 Albendazole
DB01118 Amiodarone
DB00381 Amlodipine
DB00613 Amodiaquine
DB01169 Arsenic trioxide
DB00972 Azelastine
DB04957 Azimilide
DB04975 Banoxantrone
DB06770 Benzyl alcohol
DB01393 Bezafibrate
DB00201 Caffeine
DB01136 Carvedilol
DB00608 Chloroquine
DB00356 Chlorzoxazone
DB00169 Cholecalciferol
DB00568 Cinnarizine
DB01407 Clenbuterol
DB01013 Clobetasol propionate
DB00636 Clofibrate
DB00882 Clomifene
DB00575 Clonidine
DB00363 Clozapine
DB00851 Dacarbazine
DB06292 Dapagliflozin
DB01254 Dasatinib
DB00694 Daunorubicin
DB04840 Debrisoquin
DB01234 Dexamethasone
DB00633 Dexmedetomidine
DB00586 Diclofenac
DB00804 Dicyclomine
DB00470 Dronabinol
DB08846 Ellagic Acid
DB00530 Erlotinib
DB00783 Estradiol
DB00655 Estrone
DB00898 Ethanol
DB04841 Flunarizine
DB00693 Fluorescein
DB00499 Flutamide
DB01095 Fluvastatin
DB00176 Fluvoxamine
DB00317 Gefitinib
DB00889 Granisetron
DB00502 Haloperidol
DB01064 Isoprenaline
DB01167 Itraconazole
DB01026 Ketoconazole
DB00448 Lansoprazole
DB04871 Lorcaserin
DB00643 Mebendazole
DB01065 Melatonin
DB00170 Menadione
DB00553 Methoxsalen
DB01388 Mibefradil
DB00184 Nicotine
DB01115 Nifedipine
DB00325 Nitroprusside
DB01059 Norfloxacin
DB00338 Omeprazole
DB01092 Ouabain
DB00526 Oxaliplatin
DB00738 Pentamidine
DB03783 Phenacetin
DB01174 Phenobarbital
DB00466 Picrotoxin
DB00457 Prazosin
DB01087 Primaquine
DB00396 Progesterone
DB00818 Propofol
DB00571 Propranolol
DB00165 Pyridoxine
DB00908 Quinidine
DB00468 Quinine
DB01129 Rabeprazole
DB02709 Resveratrol
DB00740 Riluzole
DB08931 Riociguat
DB06176 Romidepsin
DB00203 Sildenafil
DB00428 Streptozocin
DB00605 Sulindac
DB00675 Tamoxifen
DB04905 Tesmilifene
DB00624 Testosterone
DB01041 Thalidomide
DB00277 Theophylline
DB00730 Thiabendazole
DB00208 Ticlopidine
DB00539 Toremifene
DB00755 Tretinoin
DB00197 Troglitazone
DB00162 Vitamin A
DB00682 Warfarin
GuidetoPHARMACOLOGYi1318

Polymorphism and mutation databases

BioMutaiCYP1A1
DMDMi117139

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000516271 – 512Cytochrome P450 1A1Add BLAST512

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi67O-linked (GlcNAc) serineBy similarity1

Keywords - PTMi

Glycoprotein

Proteomic databases

EPDiP04798
MaxQBiP04798
PaxDbiP04798
PeptideAtlasiP04798
PRIDEiP04798
ProteomicsDBi51744

PTM databases

iPTMnetiP04798
PhosphoSitePlusiP04798

Expressioni

Tissue specificityi

Lung, lymphocytes and placenta.

Inductioni

By 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

Gene expression databases

BgeeiENSG00000140465 Expressed in 111 organ(s), highest expression level in liver
CleanExiHS_CYP1A1
ExpressionAtlasiP04798 baseline and differential
GenevisibleiP04798 HS

Organism-specific databases

HPAiCAB018654

Interactioni

Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

BioGridi107923, 76 interactors
IntActiP04798, 1 interactor
STRINGi9606.ENSP00000369050

Chemistry databases

BindingDBiP04798

Structurei

Secondary structure

1512
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP04798
SMRiP04798
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.Curated

Phylogenomic databases

eggNOGiKOG0156 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00900000140831
HOGENOMiHOG000036991
HOVERGENiHBG106944
InParanoidiP04798
KOiK07408
OMAiWEKCLVE
OrthoDBiEOG091G0BT8
PhylomeDBiP04798
TreeFamiTF105095

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR008066 Cyt_P450_E_grp-I_CYP1
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR01683 EP450ICYP1A
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequences (3+)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P04798-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLFPISMSAT EFLLASVIFC LVFWVIRASR PQVPKGLKNP PGPWGWPLIG
60 70 80 90 100
HMLTLGKNPH LALSRMSQQY GDVLQIRIGS TPVVVLSGLD TIRQALVRQG
110 120 130 140 150
DDFKGRPDLY TFTLISNGQS MSFSPDSGPV WAARRRLAQN GLKSFSIASD
160 170 180 190 200
PASSTSCYLE EHVSKEAEVL ISTLQELMAG PGHFNPYRYV VVSVTNVICA
210 220 230 240 250
ICFGRRYDHN HQELLSLVNL NNNFGEVVGS GNPADFIPIL RYLPNPSLNA
260 270 280 290 300
FKDLNEKFYS FMQKMVKEHY KTFEKGHIRD ITDSLIEHCQ EKQLDENANV
310 320 330 340 350
QLSDEKIINI VLDLFGAGFD TVTTAISWSL MYLVMNPRVQ RKIQEELDTV
360 370 380 390 400
IGRSRRPRLS DRSHLPYMEA FILETFRHSS FVPFTIPHST TRDTSLKGFY
410 420 430 440 450
IPKGRCVFVN QWQINHDQKL WVNPSEFLPE RFLTPDGAID KVLSEKVIIF
460 470 480 490 500
GMGKRKCIGE TIARWEVFLF LAILLQRVEF SVPLGVKVDM TPIYGLTMKH
510
ACCEHFQMQL RS
Length:512
Mass (Da):58,165
Last modified:April 1, 1988 - v1
Checksum:i3C62366044148EFD
GO
Isoform 2 (identifier: P04798-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     189-189: Y → T
     190-512: Missing.

Note: No experimental confirmation available.
Show »
Length:189
Mass (Da):20,788
Checksum:i6F774C4E9FC85427
GO
Isoform 3 (identifier: P04798-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-261: Missing.
     419-512: Missing.

Note: No experimental confirmation available.
Show »
Length:157
Mass (Da):18,441
Checksum:iD0AE3E0EEA55B854
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5J9B1Q5J9B1_HUMAN
Cytochrome P450
CYP1A1
484Annotation score:
E7EMT5E7EMT5_HUMAN
Cytochrome P450
CYP1A1
483Annotation score:
A4F3V8A4F3V8_HUMAN
Cytochrome P450 1A1
CYP1A1
175Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti26I → M in AAA52139 (PubMed:3838385).Curated1
Sequence conflicti235D → E in AAA52139 (PubMed:3838385).Curated1
Sequence conflicti381F → L in CAA26458 (PubMed:2989797).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_02319445G → D3 PublicationsCorresponds to variant dbSNP:rs4646422Ensembl.1
Natural variantiVAR_03381766M → V. Corresponds to variant dbSNP:rs35035798Ensembl.1
Natural variantiVAR_02319578I → T2 PublicationsCorresponds to variant dbSNP:rs17861094Ensembl.1
Natural variantiVAR_02470693R → W1 PublicationCorresponds to variant dbSNP:rs2229150Ensembl.1
Natural variantiVAR_024707173T → R1 PublicationCorresponds to variant dbSNP:rs28399427Ensembl.1
Natural variantiVAR_009280279R → W1 PublicationCorresponds to variant dbSNP:rs34260157Ensembl.1
Natural variantiVAR_020122286I → T. Corresponds to variant dbSNP:rs4987133Ensembl.1
Natural variantiVAR_016937331M → I in allele CYP1A1*6. 1 PublicationCorresponds to variant dbSNP:rs56313657Ensembl.1
Natural variantiVAR_016938448I → N in allele CYP1A1*8. 1 PublicationCorresponds to variant dbSNP:rs72547509Ensembl.1
Natural variantiVAR_008342461T → N in allele CYP1A1*4. 3 PublicationsCorresponds to variant dbSNP:rs1799814Ensembl.1
Natural variantiVAR_001243462I → V in allele CYP1A1*2B and allele CYP1A1*2C. 2 PublicationsCorresponds to variant dbSNP:rs1048943Ensembl.1
Natural variantiVAR_016939464R → C in allele CYP1A1*9. 1 PublicationCorresponds to variant dbSNP:rs41279188Ensembl.1
Natural variantiVAR_016940464R → S in allele CYP1A1*5. 1 PublicationCorresponds to variant dbSNP:rs41279188Ensembl.1
Natural variantiVAR_033818470F → V. Corresponds to variant dbSNP:rs36121583Ensembl.1
Natural variantiVAR_016941477R → W in allele CYP1A1*10. 2 PublicationsCorresponds to variant dbSNP:rs56240201Ensembl.1
Natural variantiVAR_024708482V → M1 PublicationCorresponds to variant dbSNP:rs28399429Ensembl.1
Natural variantiVAR_016942492P → R in allele CYP1A1*11. 2 PublicationsCorresponds to variant dbSNP:rs28399430Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0533631 – 261Missing in isoform 3. 1 PublicationAdd BLAST261
Alternative sequenceiVSP_053364189Y → T in isoform 2. 1 Publication1
Alternative sequenceiVSP_053365190 – 512Missing in isoform 2. 1 PublicationAdd BLAST323
Alternative sequenceiVSP_053366419 – 512Missing in isoform 3. 1 PublicationAdd BLAST94

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X02612 Genomic DNA Translation: CAA26458.1
K03191 mRNA Translation: AAA52139.1
X04300 Genomic DNA Translation: CAA27843.1
AF253322 Genomic DNA Translation: AAK25727.1
AM233518 mRNA Translation: CAJ80721.1
AM233519 mRNA Translation: CAJ80722.1
AM233520 mRNA Translation: CAJ80723.1
AK223113 mRNA Translation: BAD96833.1
AC091230 Genomic DNA No translation available.
BC023019 mRNA Translation: AAH23019.1
M12079 mRNA Translation: AAA52152.1
AF040259 mRNA Translation: AAD10199.1
CCDSiCCDS10268.1 [P04798-1]
PIRiA24797 O4HU6
RefSeqiNP_000490.1, NM_000499.4 [P04798-1]
NP_001306145.1, NM_001319216.1
NP_001306146.1, NM_001319217.1 [P04798-1]
UniGeneiHs.72912

Genome annotation databases

EnsembliENST00000379727; ENSP00000369050; ENSG00000140465 [P04798-1]
ENST00000395048; ENSP00000378488; ENSG00000140465 [P04798-1]
ENST00000562201; ENSP00000455340; ENSG00000140465 [P04798-2]
ENST00000564596; ENSP00000457668; ENSG00000140465 [P04798-3]
ENST00000567032; ENSP00000456585; ENSG00000140465 [P04798-1]
ENST00000569630; ENSP00000455051; ENSG00000140465 [P04798-2]
GeneIDi1543
KEGGihsa:1543
UCSCiuc002ayp.4 human [P04798-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Similar proteinsi

Cross-referencesi

Web resourcesi

Cytochrome P450 Allele Nomenclature Committee

CYP1A1 alleles

SHMPD

The Singapore human mutation and polymorphism database

Wikipedia

CYP1A1 entry

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X02612 Genomic DNA Translation: CAA26458.1
K03191 mRNA Translation: AAA52139.1
X04300 Genomic DNA Translation: CAA27843.1
AF253322 Genomic DNA Translation: AAK25727.1
AM233518 mRNA Translation: CAJ80721.1
AM233519 mRNA Translation: CAJ80722.1
AM233520 mRNA Translation: CAJ80723.1
AK223113 mRNA Translation: BAD96833.1
AC091230 Genomic DNA No translation available.
BC023019 mRNA Translation: AAH23019.1
M12079 mRNA Translation: AAA52152.1
AF040259 mRNA Translation: AAD10199.1
CCDSiCCDS10268.1 [P04798-1]
PIRiA24797 O4HU6
RefSeqiNP_000490.1, NM_000499.4 [P04798-1]
NP_001306145.1, NM_001319216.1
NP_001306146.1, NM_001319217.1 [P04798-1]
UniGeneiHs.72912

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4I8VX-ray2.60A/B/C/D35-512[»]
ProteinModelPortaliP04798
SMRiP04798
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi107923, 76 interactors
IntActiP04798, 1 interactor
STRINGi9606.ENSP00000369050

Chemistry databases

BindingDBiP04798
ChEMBLiCHEMBL2231
DrugBankiDB02342 2-Methoxyestradiol
DB00316 Acetaminophen
DB00518 Albendazole
DB01118 Amiodarone
DB00381 Amlodipine
DB00613 Amodiaquine
DB01169 Arsenic trioxide
DB00972 Azelastine
DB04957 Azimilide
DB04975 Banoxantrone
DB06770 Benzyl alcohol
DB01393 Bezafibrate
DB00201 Caffeine
DB01136 Carvedilol
DB00608 Chloroquine
DB00356 Chlorzoxazone
DB00169 Cholecalciferol
DB00568 Cinnarizine
DB01407 Clenbuterol
DB01013 Clobetasol propionate
DB00636 Clofibrate
DB00882 Clomifene
DB00575 Clonidine
DB00363 Clozapine
DB00851 Dacarbazine
DB06292 Dapagliflozin
DB01254 Dasatinib
DB00694 Daunorubicin
DB04840 Debrisoquin
DB01234 Dexamethasone
DB00633 Dexmedetomidine
DB00586 Diclofenac
DB00804 Dicyclomine
DB00470 Dronabinol
DB08846 Ellagic Acid
DB00530 Erlotinib
DB00783 Estradiol
DB00655 Estrone
DB00898 Ethanol
DB04841 Flunarizine
DB00693 Fluorescein
DB00499 Flutamide
DB01095 Fluvastatin
DB00176 Fluvoxamine
DB00317 Gefitinib
DB00889 Granisetron
DB00502 Haloperidol
DB01064 Isoprenaline
DB01167 Itraconazole
DB01026 Ketoconazole
DB00448 Lansoprazole
DB04871 Lorcaserin
DB00643 Mebendazole
DB01065 Melatonin
DB00170 Menadione
DB00553 Methoxsalen
DB01388 Mibefradil
DB00184 Nicotine
DB01115 Nifedipine
DB00325 Nitroprusside
DB01059 Norfloxacin
DB00338 Omeprazole
DB01092 Ouabain
DB00526 Oxaliplatin
DB00738 Pentamidine
DB03783 Phenacetin
DB01174 Phenobarbital
DB00466 Picrotoxin
DB00457 Prazosin
DB01087 Primaquine
DB00396 Progesterone
DB00818 Propofol
DB00571 Propranolol
DB00165 Pyridoxine
DB00908 Quinidine
DB00468 Quinine
DB01129 Rabeprazole
DB02709 Resveratrol
DB00740 Riluzole
DB08931 Riociguat
DB06176 Romidepsin
DB00203 Sildenafil
DB00428 Streptozocin
DB00605 Sulindac
DB00675 Tamoxifen
DB04905 Tesmilifene
DB00624 Testosterone
DB01041 Thalidomide
DB00277 Theophylline
DB00730 Thiabendazole
DB00208 Ticlopidine
DB00539 Toremifene
DB00755 Tretinoin
DB00197 Troglitazone
DB00162 Vitamin A
DB00682 Warfarin
GuidetoPHARMACOLOGYi1318
SwissLipidsiSLP:000001329

PTM databases

iPTMnetiP04798
PhosphoSitePlusiP04798

Polymorphism and mutation databases

BioMutaiCYP1A1
DMDMi117139

Proteomic databases

EPDiP04798
MaxQBiP04798
PaxDbiP04798
PeptideAtlasiP04798
PRIDEiP04798
ProteomicsDBi51744

Protocols and materials databases

DNASUi1543
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000379727; ENSP00000369050; ENSG00000140465 [P04798-1]
ENST00000395048; ENSP00000378488; ENSG00000140465 [P04798-1]
ENST00000562201; ENSP00000455340; ENSG00000140465 [P04798-2]
ENST00000564596; ENSP00000457668; ENSG00000140465 [P04798-3]
ENST00000567032; ENSP00000456585; ENSG00000140465 [P04798-1]
ENST00000569630; ENSP00000455051; ENSG00000140465 [P04798-2]
GeneIDi1543
KEGGihsa:1543
UCSCiuc002ayp.4 human [P04798-1]

Organism-specific databases

CTDi1543
DisGeNETi1543
EuPathDBiHostDB:ENSG00000140465.13
GeneCardsiCYP1A1
HGNCiHGNC:2595 CYP1A1
HPAiCAB018654
MIMi108330 gene
neXtProtiNX_P04798
OpenTargetsiENSG00000140465
PharmGKBiPA27092
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0156 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00900000140831
HOGENOMiHOG000036991
HOVERGENiHBG106944
InParanoidiP04798
KOiK07408
OMAiWEKCLVE
OrthoDBiEOG091G0BT8
PhylomeDBiP04798
TreeFamiTF105095

Enzyme and pathway databases

ReactomeiR-HSA-1989781 PPARA activates gene expression
R-HSA-211981 Xenobiotics
R-HSA-2142670 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
R-HSA-2142816 Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
R-HSA-9018681 Biosynthesis of protectins
SABIO-RKiP04798
SIGNORiP04798

Miscellaneous databases

ChiTaRSiCYP1A1 human
GeneWikiiCytochrome_P450,_family_1,_member_A1
GenomeRNAii1543
PROiPR:P04798
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000140465 Expressed in 111 organ(s), highest expression level in liver
CleanExiHS_CYP1A1
ExpressionAtlasiP04798 baseline and differential
GenevisibleiP04798 HS

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR008066 Cyt_P450_E_grp-I_CYP1
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR01683 EP450ICYP1A
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCP1A1_HUMAN
AccessioniPrimary (citable) accession number: P04798
Secondary accession number(s): A4F3V9, A4F3W0, Q53G18
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: April 1, 1988
Last modified: November 7, 2018
This is version 206 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
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