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Protein

Metallothionein-A

Gene

MTA

Organism
Strongylocentrotus purpuratus (Purple sea urchin)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Metallothioneins have a high content of cysteine residues that bind various heavy metals.

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Metal-thiolate cluster

Names & Taxonomyi

Protein namesi
Recommended name:
Metallothionein-A
Short name:
MTA
Gene namesi
Name:MTA
OrganismiStrongylocentrotus purpuratus (Purple sea urchin)
Taxonomic identifieri7668 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaEchinoidaStrongylocentrotidaeStrongylocentrotus
Proteomesi
  • UP000007110 Componenti: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001973471 – 64Metallothionein-AAdd BLAST64

Proteomic databases

PRIDEiP04734

Expressioni

Inductioni

By heavy metals.

Structurei

Secondary structure

164
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP04734
SMRiP04734
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP04734

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiView protein in InterPro
IPR017980 Metalthion_4_echinoid/annelid
IPR001396 Metalthion_4_echinoidea
IPR017854 Metalthion_dom_sf
PfamiView protein in Pfam
PF05522 Metallothio_6, 1 hit
PRINTSiPR00873 MTECHINOIDEA
SUPFAMiSSF57868 SSF57868, 2 hits

Sequencei

Sequence statusi: Complete.

P04734-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPDVKCVCCK EGKECACFGQ DCCKTGECCK DGTCCGICTN AACKCANGCK
60
CGSGCSCTEG NCAC
Length:64
Mass (Da):6,445
Last modified:April 1, 1990 - v2
Checksum:i66F0AA7A4991E3E6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti10K → T in AAA30061 (PubMed:3860837).Curated1
Sequence conflicti24K → V in AAA30061 (PubMed:3860837).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M30606 Genomic DNA Translation: AAA30067.1
K02464 mRNA Translation: AAA30061.1
PIRiA25775
A33825
RefSeqiNP_999742.1, NM_214577.1
UniGeneiSpu.96

Genome annotation databases

GeneIDi373380
KEGGispu:373380

Similar proteinsi

Entry informationi

Entry nameiMTA_STRPU
AccessioniPrimary (citable) accession number: P04734
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: April 1, 1990
Last modified: May 23, 2018
This is version 90 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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