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Protein

Transcription factor 1

Gene

TF1

Organism
Bacillus phage SP01 (Bacteriophage SP01)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Selectively binds to and inhibits the transcription of hydroxymethyluracil-(hmUra)-containing DNA, such as SP01 DNA, by RNA polymerase in vitro.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi611
DNA bindingi93 – 94Sequence analysis2

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor 1
Gene namesi
Name:TF1
OrganismiBacillus phage SP01 (Bacteriophage SP01)
Taxonomic identifieri10685 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesMyoviridaeSpounavirinaeSpo1virus
Virus hostiBacillus subtilis [TaxID: 1423]

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001050821 – 99Transcription factor 1Add BLAST99

Interactioni

Subunit structurei

Homodimer.

Structurei

Secondary structure

199
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi5 – 14Combined sources10
Helixi21 – 38Combined sources18
Turni45 – 47Combined sources3
Beta strandi49 – 53Combined sources5
Beta strandi63 – 67Combined sources5
Beta strandi76 – 80Combined sources5
Helixi83 – 92Combined sources10
Helixi94 – 98Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1EXENMR-A/B1-99[»]
1WTUNMR-A/B1-99[»]
ProteinModelPortaliP04445
SMRiP04445
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP04445

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni52 – 77May be involved in preference for HM-URA DNAAdd BLAST26
Regioni90 – 99May be involved in preference for HM-URA DNA10

Sequence similaritiesi

Phylogenomic databases

KOiK03530

Family and domain databases

Gene3Di4.10.520.10, 1 hit
InterProiView protein in InterPro
IPR000119 Hist_DNA-bd
IPR020816 Histone-like_DNA-bd_CS
IPR010992 IHF-like_DNA-bd_dom_sf
PANTHERiPTHR33175 PTHR33175, 1 hit
PfamiView protein in Pfam
PF00216 Bac_DNA_binding, 1 hit
PRINTSiPR01727 DNABINDINGHU
SMARTiView protein in SMART
SM00411 BHL, 1 hit
SUPFAMiSSF47729 SSF47729, 1 hit
PROSITEiView protein in PROSITE
PS00045 HISTONE_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

P04445-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKTELIKAI AQDTELTQVS VSKMLASFEK ITTETVAKGD KVQLTGFLNI
60 70 80 90
KPVARQARKG FNPQTQEALE IAPSVGVSVK PGESLKKAAE GLKYEDFAK
Length:99
Mass (Da):10,737
Last modified:August 13, 1987 - v1
Checksum:i3F8CD237A46EFC37
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K02381 Genomic DNA Translation: AAA32599.1
PIRiA02693 DNBP11
RefSeqiYP_002300416.1, NC_011421.1

Genome annotation databases

GeneIDi7009134
KEGGivg:7009134

Similar proteinsi

Entry informationi

Entry nameiTF1_BPSP1
AccessioniPrimary (citable) accession number: P04445
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 13, 1987
Last sequence update: August 13, 1987
Last modified: November 22, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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