UniProtKB - P03999 (OPSB_HUMAN)

BLAST

>sp|P03999|OPSB_HUMAN Short-wave-sensitive opsin 1 OS=Homo sapiens OX=9606 GN=OPN1SW PE=1 SV=1
MRKMSEEEFYLFKNISSVGPWDGPQYHIAPVWAFYLQAAFMGTVFLIGFPLNAMVLVATL
RYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVASCNGYFVFGRHVCALEGFLGTVAGLV
TGWSLAFLAFERYIVICKPFGNFRFSSKHALTVVLATWTIGIGVSIPPFFGWSRFIPEGL
QCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQQQESATT
QKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHGLDLRLVTIPSFFSKSACIYNP
IIYCFMNKQFQACIMKMVCGKAMTDESDTCSSQKTEVSTVSSTQVGPN

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History
Entry version 176 (07 Nov 2018)
Sequence version 1 (23 Oct 1986)
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Protein

Short-wave-sensitive opsin 1

Gene

OPN1SW

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

Absorptionⁱ

Abs(max)=420 nm

GO - Molecular functionⁱ

G protein-coupled photoreceptor activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
signaling receptor activity
Source: ProtInc
Traceable author statementⁱ
- 2937147

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cellular response to light stimulus
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
G protein-coupled receptor signaling pathway
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
phototransduction
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
protein-chromophore linkage Source: UniProtKB-KW
retinoid metabolic process Source: Reactome
signal transduction
Source: ProtInc
Traceable author statementⁱ
- 2937147
visual perception
Source: ProtInc
Traceable author statementⁱ
- 9089077

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer
Biological process	Sensory transduction, Vision
Ligand	Chromophore

Enzyme and pathway databases

Reactomeⁱ	R-HSA-2187335 The retinoid cycle in cones (daylight vision) R-HSA-2453864 Retinoid cycle disease events R-HSA-418594 G alpha (i) signalling events R-HSA-419771 Opsins

Reactomeⁱ

R-HSA-2187335 The retinoid cycle in cones (daylight vision)
R-HSA-2453864 Retinoid cycle disease events
R-HSA-418594 G alpha (i) signalling events
R-HSA-419771 Opsins

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Short-wave-sensitive opsin 1 Alternative name(s): Blue cone photoreceptor pigment Blue-sensitive opsin Short name: BOP
Gene namesⁱ	Name:OPN1SW Synonyms:BCP
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 7

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000128617.2
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:1012 OPN1SW
MIMⁱ	613522 gene
neXtProtⁱ	NX_P03999

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 33	ExtracellularSequence analysisAdd BLAST	33
Transmembraneⁱ	34 – 58	Helical; Name=1Sequence analysisAdd BLAST	25
Topological domainⁱ	59 – 70	CytoplasmicSequence analysisAdd BLAST	12
Transmembraneⁱ	71 – 96	Helical; Name=2Sequence analysisAdd BLAST	26
Topological domainⁱ	97 – 110	ExtracellularSequence analysisAdd BLAST	14
Transmembraneⁱ	111 – 130	Helical; Name=3Sequence analysisAdd BLAST	20
Topological domainⁱ	131 – 149	CytoplasmicSequence analysisAdd BLAST	19
Transmembraneⁱ	150 – 173	Helical; Name=4Sequence analysisAdd BLAST	24
Topological domainⁱ	174 – 199	ExtracellularSequence analysisAdd BLAST	26
Transmembraneⁱ	200 – 227	Helical; Name=5Sequence analysisAdd BLAST	28
Topological domainⁱ	228 – 249	CytoplasmicSequence analysisAdd BLAST	22
Transmembraneⁱ	250 – 273	Helical; Name=6Sequence analysisAdd BLAST	24
Topological domainⁱ	274 – 281	ExtracellularSequence analysis	8
Transmembraneⁱ	282 – 306	Helical; Name=7Sequence analysisAdd BLAST	25
Topological domainⁱ	307 – 348	CytoplasmicSequence analysisAdd BLAST	42

Keywords - Cellular componentⁱ

Membrane

Pathology & Biotechⁱ

Involvement in diseaseⁱ

Tritan color blindness (CBT)2 Publications

The disease is caused by mutations affecting the gene represented in this entry.

Disease descriptionA disorder of vision characterized by a selective deficiency of blue spectral sensitivity.

Keywords - Diseaseⁱ

Disease mutation

Organism-specific databases

DisGeNET More...DisGeNETⁱ	611
MalaCards human disease database More...MalaCardsⁱ	OPN1SW
MIMⁱ	190900 phenotype
Open Targets More...OpenTargetsⁱ	ENSG00000128617
Orphanetⁱ	88629 Tritanopia
PharmGKBⁱ	PA31938

Polymorphism and mutation databases

BioMutaⁱ	OPN1SW
DMDMⁱ	129203

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000197762	1 – 348	Short-wave-sensitive opsin 1Add BLAST		348

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Glycosylationⁱ	14	N-linked (GlcNAc...) asparagineCurated	1
Disulfide bondⁱ	107 ↔ 184	PROSITE-ProRule annotation
Modified residueⁱ	293	N6-(retinylidene)lysine	1

Post-translational modificationⁱ

Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.

Keywords - PTMⁱ

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbⁱ	P03999
PeptideAtlas More...PeptideAtlasⁱ	P03999
PRIDEⁱ	P03999
ProteomicsDBⁱ	51629

PTM databases

iPTMnetⁱ	P03999
PhosphoSitePlusⁱ	P03999

Expressionⁱ

Tissue specificityⁱ

The three color pigments are found in the cone photoreceptor cells.

Gene expression databases

Bgeeⁱ	ENSG00000128617 Expressed in 93 organ(s), highest expression level in lower esophagus
CleanExⁱ	HS_OPN1SW
ExpressionAtlasⁱ	P03999 baseline and differential
Genevisibleⁱ	P03999 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA013562 HPA014083

HPAⁱ

HPA013562
HPA014083

Interactionⁱ

Protein-protein interaction databases

IntActⁱ	P03999, 1 interactor
STRINGⁱ	9606.ENSP00000249389

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P03999
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.PROSITE-ProRule annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG3656 Eukaryota ENOG410XRW9 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118977
HOGENOMⁱ	HOG000253932
HOVERGENⁱ	HBG107442
InParanoidⁱ	P03999
KEGG Orthology (KO) More...KOⁱ	K04252
OMAⁱ	ACIMEMV
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0BDA
PhylomeDBⁱ	P03999
TreeFamⁱ	TF324998

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR001760 Opsin IPR001521 Opsin_blue IPR027430 Retinal_BS
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN PR00238 OPSIN PR00574 OPSINBLUE
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit PS00238 OPSIN, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P03999-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MRKMSEEEFY LFKNISSVGP WDGPQYHIAP VWAFYLQAAF MGTVFLIGFP 
        60         70         80         90        100
LNAMVLVATL RYKKLRQPLN YILVNVSFGG FLLCIFSVFP VFVASCNGYF 
       110        120        130        140        150
VFGRHVCALE GFLGTVAGLV TGWSLAFLAF ERYIVICKPF GNFRFSSKHA 
       160        170        180        190        200
LTVVLATWTI GIGVSIPPFF GWSRFIPEGL QCSCGPDWYT VGTKYRSESY 
       210        220        230        240        250
TWFLFIFCFI VPLSLICFSY TQLLRALKAV AAQQQESATT QKAEREVSRM 
       260        270        280        290        300
VVVMVGSFCV CYVPYAAFAM YMVNNRNHGL DLRLVTIPSF FSKSACIYNP 
       310        320        330        340 
IIYCFMNKQF QACIMKMVCG KAMTDESDTC SSQKTEVSTV SSTQVGPN

Length:348

Mass (Da):39,135

Last modified:October 23, 1986 - v1

Checksum:ⁱ83FAB2E7111CB581

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	308 – 310	KQF → VKL (PubMed:2565599).Curated		3

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_004838	79	G → R in CBT. 1 PublicationCorresponds to variant dbSNP:rs104894031EnsemblClinVar.	1
Natural variantⁱVAR_004839	214	S → P in CBT. 1 PublicationCorresponds to variant dbSNP:rs104894032EnsemblClinVar.	1
Natural variantⁱVAR_004840	264	P → S in CBT. 2 PublicationsCorresponds to variant dbSNP:rs104894033EnsemblClinVar.	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M13299 , M13295, M13296, M13297, M13298 Genomic DNA Translation: AAB05207.1 U53874 Genomic DNA Translation: AAC51334.1 L32835 Genomic DNA Translation: AAL31362.1 M26172 mRNA Translation: AAA35608.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS5806.1
PIRⁱ	A03156 OOHUB
NCBI Reference Sequences More...RefSeqⁱ	NP_001699.1, NM_001708.2
UniGeneⁱ	Hs.656404

Genome annotation databases

Ensemblⁱ	ENST00000249389; ENSP00000249389; ENSG00000128617
GeneIDⁱ	611
KEGGⁱ	hsa:611

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P03999	Short-wave-sensitive opsin 1		PANPA		348	UniRef100_P03999
Short-wave-sensitive opsin 1		PANTR		348
Opsin 1 (Cone pigments), short-wave-sensitive (Color blindness, tritan)		HUMAN		348
OPN1SW isoform 1		PANTR		348

Protein	Similar proteins		Species	Score	Length	Source
P03999	Short-wave-sensitive opsin 1		PANPA		348	UniRef90_P03999
Short-wave-sensitive opsin 1		PANTR		348
Short-wave-sensitive opsin 1		SAIBB		349
Opsin 1 (Cone pigments), short-wave-sensitive (Color blindness, tritan)		HUMAN		348
Uncharacterized protein		CALJA		350
+23

Protein	Similar proteins		Species	Score	Length	Source
P03999	Short-wave-sensitive opsin 1		PANPA		348	UniRef50_P03999
Short-wave-sensitive opsin 1		PANTR		348
Short-wave-sensitive opsin 1		SAIBB		349
Short-wave-sensitive opsin 1		BOVIN		349
Short-wave-sensitive opsin 1		RAT		346
+701

Cross-referencesⁱ

Web resourcesⁱ

Mutations of the color pigment genes

Retina International's Scientific Newsletter

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M13299 , M13295, M13296, M13297, M13298 Genomic DNA Translation: AAB05207.1 U53874 Genomic DNA Translation: AAC51334.1 L32835 Genomic DNA Translation: AAL31362.1 M26172 mRNA Translation: AAA35608.1
CCDSⁱ	CCDS5806.1
PIRⁱ	A03156 OOHUB
RefSeqⁱ	NP_001699.1, NM_001708.2
UniGeneⁱ	Hs.656404

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	1KPN	model	-	A	1-348	[»]
ProteinModelPortalⁱ	P03999
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	P03999, 1 interactor
STRINGⁱ	9606.ENSP00000249389

Protein family/group databases

GPCRDBⁱ	Search...

GPCRDBⁱ

Search...

PTM databases

iPTMnetⁱ	P03999
PhosphoSitePlusⁱ	P03999

Polymorphism and mutation databases

BioMutaⁱ	OPN1SW
DMDMⁱ	129203

Proteomic databases

PaxDbⁱ	P03999
PeptideAtlasⁱ	P03999
PRIDEⁱ	P03999
ProteomicsDBⁱ	51629

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	611
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000249389; ENSP00000249389; ENSG00000128617
GeneIDⁱ	611
KEGGⁱ	hsa:611

Organism-specific databases

CTDⁱ	611
DisGeNETⁱ	611
EuPathDBⁱ	HostDB:ENSG00000128617.2
GeneCardsⁱ	OPN1SW
H-InvDBⁱ	HIX0167900
HGNCⁱ	HGNC:1012 OPN1SW
HPAⁱ	HPA013562 HPA014083
MalaCardsⁱ	OPN1SW
MIMⁱ	190900 phenotype 613522 gene
neXtProtⁱ	NX_P03999
OpenTargetsⁱ	ENSG00000128617
Orphanetⁱ	88629 Tritanopia
PharmGKBⁱ	PA31938
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG3656 Eukaryota ENOG410XRW9 LUCA
GeneTreeⁱ	ENSGT00760000118977
HOGENOMⁱ	HOG000253932
HOVERGENⁱ	HBG107442
InParanoidⁱ	P03999
KOⁱ	K04252
OMAⁱ	ACIMEMV
OrthoDBⁱ	EOG091G0BDA
PhylomeDBⁱ	P03999
TreeFamⁱ	TF324998

Enzyme and pathway databases

Reactomeⁱ	R-HSA-2187335 The retinoid cycle in cones (daylight vision) R-HSA-2453864 Retinoid cycle disease events R-HSA-418594 G alpha (i) signalling events R-HSA-419771 Opsins

Reactomeⁱ

R-HSA-2187335 The retinoid cycle in cones (daylight vision)
R-HSA-2453864 Retinoid cycle disease events
R-HSA-418594 G alpha (i) signalling events
R-HSA-419771 Opsins

Miscellaneous databases

GeneWikiⁱ	OPN1SW
GenomeRNAiⁱ	611
Protein Ontology More...PROⁱ	PR:P03999
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000128617 Expressed in 93 organ(s), highest expression level in lower esophagus
CleanExⁱ	HS_OPN1SW
ExpressionAtlasⁱ	P03999 baseline and differential
Genevisibleⁱ	P03999 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR001760 Opsin IPR001521 Opsin_blue IPR027430 Retinal_BS
Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN PR00238 OPSIN PR00574 OPSINBLUE
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit PS00238 OPSIN, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	OPSB_HUMAN
Accessionⁱ	P03999Primary (citable) accession number: P03999 Secondary accession number(s): Q13877
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 23, 1986
	Last sequence update:	October 23, 1986
	Last modified:	November 7, 2018
	This is version 176 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
Human chromosome 7
Human chromosome 7: entries, gene names and cross-references to MIM
7-transmembrane G-linked receptors
List of 7-transmembrane G-linked receptor entries

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UniProtKB - P03999 (OPSB_HUMAN)

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Short-wave-sensitive opsin 1

OPN1SW

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Absorptioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Keywords - Diseasei

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

Absorptionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

Keywords - Diseaseⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Web resourcesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ