TRGV3

Functionⁱ

GO - Molecular functionⁱ

MHC protein binding
Source: UniProtKB
Non-traceable author statementⁱ
- 3458221
peptide antigen binding
Source: UniProtKB
Non-traceable author statementⁱ
- 3458221

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

immune response
Source: UniProtKB
Non-traceable author statementⁱ
- 3458221

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Receptor

Molecular function

Receptor

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: T cell receptor gamma variable 3Imported Alternative name(s): T-cell receptor gamma V-gamma-1.1 region1 Publication
Gene namesⁱ	Name:TRGV3Imported Synonyms:TCRB, TCRGV3Imported
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 7

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000211699.2
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:12288 TRGV3
neXtProtⁱ	NX_P03979

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	6976
Open Targets More...OpenTargetsⁱ	ENSG00000211699

Chemistry databases

ChEMBLⁱ	CHEMBL3580506

ChEMBLⁱ

CHEMBL3580506

Polymorphism and mutation databases

DMDMⁱ	136506

DMDMⁱ

136506

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 17	Sequence analysisAdd BLAST		17
ChainⁱPRO_0000033611	18 – 118	T cell receptor gamma variable 3Sequence analysisAdd BLAST		101

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Disulfide bondⁱ	41 ↔ 113	PROSITE-ProRule annotation
Glycosylationⁱ	106	N-linked (GlcNAc...) asparagineSequence analysis		1

Keywords - PTMⁱ

Disulfide bond, Glycoprotein

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	P03979
PRIDEⁱ	P03979
ProteomicsDBⁱ	51626

PTM databases

iPTMnetⁱ	P03979
PhosphoSitePlusⁱ	P03979

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000211699

Bgeeⁱ

ENSG00000211699

Interactionⁱ

GO - Molecular functionⁱ

MHC protein binding
Source: UniProtKB
Non-traceable author statementⁱ
- 3458221

View the complete GO annotation on QuickGO ...

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P03979
SMRⁱ	P03979
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	18 – ›118	Ig-likePROSITE-ProRule annotationAdd BLAST		›101

Keywords - Domainⁱ

Immunoglobulin domain, Signal

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00440000034436
HOGENOMⁱ	HOG000169587
HOVERGENⁱ	HBG007785
InParanoidⁱ	P03979
OMAⁱ	RWSWILR
PhylomeDBⁱ	P03979

Family and domain databases

Gene3Dⁱ	2.60.40.10, 1 hit
InterProⁱ	View protein in InterPro IPR007110 Ig-like_dom IPR036179 Ig-like_dom_sf IPR013783 Ig-like_fold IPR013106 Ig_V-set
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF07686 V-set, 1 hit
SUPFAMⁱ	SSF48726 SSF48726, 1 hit
PROSITEⁱ	View protein in PROSITE PS50835 IG_LIKE, 1 hit

Sequenceⁱ

Sequence statusⁱ: Fragment.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

P03979-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MRWALLVLLA FLSPASQKSS NLEGRTKSVT RQTGSSAEIT CDLTVTNTFY 
        60         70         80         90        100
IHWYLHQEGK APQRLLYYDV STARDVLESG LSPGKYYTHT PRRWSWILRL 
       110 
QNLIENDSGV YYCATWDR

Length:118

Mass (Da):13,664

Last modified:July 6, 2016 - v2

Checksum:ⁱ2C30297BFA6C584A

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	118			1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M13231 mRNA No translation available. AC007245 Genomic DNA No translation available. X04038 Genomic DNA Translation: CAA27672.1
PIRⁱ	A02017 RWHUGV
UniGeneⁱ	Hs.731375

Genome annotation databases

Ensemblⁱ	ENST00000390346; ENSP00000374869; ENSG00000211699
UCSC genome browser More...UCSCⁱ	uc064cyb.1 human

Protein	Similar proteins		Species	Score	Length
P03979	T-cell gamma protein (Fragment)	)	HUMAN		133
TRGV3 isoform 1 (Fragment)		PANTR		118
TRGV2 isoform 1 (Fragment)		PONAB		118
T cell receptor gamma variable 5 (Fragment)		HUMAN		118
TRGV4 isoform 1 (Fragment)		PANTR		118

Protein	Similar proteins		Species	Score	Length
P03979	T-cell gamma protein (Fragment)	)	HUMAN		133
TRGV2 isoform 1 (Fragment)		PONAB		118
TRGV4 isoform 1 (Fragment)		PANTR		118
Uncharacterized protein		HORSE		119
Uncharacterized protein (Fragment)		MACFA		117
+21

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M13231 mRNA No translation available. AC007245 Genomic DNA No translation available. X04038 Genomic DNA Translation: CAA27672.1
PIRⁱ	A02017 RWHUGV
UniGeneⁱ	Hs.731375

3D structure databases

ProteinModelPortalⁱ	P03979
SMRⁱ	P03979
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Chemistry databases

ChEMBLⁱ	CHEMBL3580506

ChEMBLⁱ

CHEMBL3580506

PTM databases

iPTMnetⁱ	P03979
PhosphoSitePlusⁱ	P03979

Polymorphism and mutation databases

DMDMⁱ	136506

DMDMⁱ

136506

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	P03979
PRIDEⁱ	P03979
ProteomicsDBⁱ	51626

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000390346; ENSP00000374869; ENSG00000211699
UCSC genome browser More...UCSCⁱ	uc064cyb.1 human

Organism-specific databases

DisGeNET More...DisGeNETⁱ	6976
EuPathDBⁱ	HostDB:ENSG00000211699.2
GeneCardsⁱ	TRGV3
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:12288 TRGV3
neXtProtⁱ	NX_P03979
Open Targets More...OpenTargetsⁱ	ENSG00000211699
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00440000034436
HOGENOMⁱ	HOG000169587
HOVERGENⁱ	HBG007785
InParanoidⁱ	P03979
OMAⁱ	RWSWILR
PhylomeDBⁱ	P03979

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P03979

PROⁱ

PR:P03979

Gene expression databases

Bgeeⁱ	ENSG00000211699

Bgeeⁱ

ENSG00000211699

Family and domain databases

Gene3Dⁱ	2.60.40.10, 1 hit
InterProⁱ	View protein in InterPro IPR007110 Ig-like_dom IPR036179 Ig-like_dom_sf IPR013783 Ig-like_fold IPR013106 Ig_V-set
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF07686 V-set, 1 hit
SUPFAMⁱ	SSF48726 SSF48726, 1 hit
PROSITEⁱ	View protein in PROSITE PS50835 IG_LIKE, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	TRGV3_HUMAN
Accessionⁱ	P03979Primary (citable) accession number: P03979 Secondary accession number(s): A0A075B6L3
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 23, 1986
	Last sequence update:	July 6, 2016
	Last modified:	June 20, 2018
	This is version 126 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 7
Human chromosome 7: entries, gene names and cross-references to MIM

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P03979 (TRGV3_HUMAN)

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T cell receptor gamma variable 3

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Chemistry databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ