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Protein

Putative COX1/OXI3 intron 1 protein

Gene

AI1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Miscellaneous

This protein is coded in group-II intron 1 of OXI3 (COX1).

GO - Molecular functioni

  • RNA-directed DNA polymerase activity Source: SGD

GO - Biological processi

  • homing of group II introns Source: SGD
  • mitochondrial mRNA processing Source: GO_Central
  • mRNA processing Source: SGD
  • oxidation-reduction process Source: InterPro
  • RNA-dependent DNA biosynthetic process Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-34372-MONOMER

Protein family/group databases

REBASEi2622 I-SceIII

Names & Taxonomyi

Protein namesi
Recommended name:
Putative COX1/OXI3 intron 1 protein
Gene namesi
Name:AI1
Ordered Locus Names:Q0050
Encoded oniMitochondrion
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Mitochondrion

Organism-specific databases

SGDiS000007261 AI1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001968801 – 834Putative COX1/OXI3 intron 1 proteinAdd BLAST834

Proteomic databases

MaxQBiP03875
PaxDbiP03875
PRIDEiP03875

Interactioni

Protein-protein interaction databases

BioGridi34785, 7 interactors
DIPiDIP-8242N
IntActiP03875, 1 interactor
MINTiP03875
STRINGi4932.Q0050

Structurei

3D structure databases

ProteinModelPortaliP03875
SMRiP03875
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini296 – 577Reverse transcriptasePROSITE-ProRule annotationAdd BLAST282

Phylogenomic databases

GeneTreeiENSGT00840000130858
HOGENOMiHOG000172601
InParanoidiP03875
OMAiTYQQEYR
OrthoDBiEOG092C47G1

Family and domain databases

CDDicd00085 HNHc, 1 hit
Gene3Di1.20.210.10, 1 hit
InterProiView protein in InterPro
IPR036927 Cyt_c_oxase-like_su1_sf
IPR024937 Domain_X
IPR003615 HNH_nuc
IPR000477 RT_dom
PfamiView protein in Pfam
PF01348 Intron_maturas2, 1 hit
PF00078 RVT_1, 1 hit
SMARTiView protein in SMART
SM00507 HNHc, 1 hit
SUPFAMiSSF81442 SSF81442, 1 hit
PROSITEiView protein in PROSITE
PS50878 RT_POL, 1 hit

Sequencei

Sequence statusi: Complete.

P03875-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVQRWLYSTN AKDIAVLYFM LAIFSGMAGT AMSLIIRLEL AAPGSQYLHG
60 70 80 90 100
NSQLFNGAPT SAYISLMRTA LVLWIINRYL KHMTNSVGAN FTGTMACHKT
110 120 130 140 150
PMISVGGVKC YMVRLTNFLQ VFIRITISSY HLDMVKQVWL FYVEVIRLWF
160 170 180 190 200
IVLDSTGSVK KMKDTNNTKG NTKSEGSTER GNSGVDRGMV VPNTQMKMRF
210 220 230 240 250
LNQVRYYSVN NNLKMGKDTN IELSKDTSTS DLLEFEKLVM DNMNEENMNN
260 270 280 290 300
NLLSIMKNVD MLMLAYNRIK SKPGNMTPGT TLETLDGMNM MYLNKLSNEL
310 320 330 340 350
GTGKFKFKPM RMVNIPKPKG GMRPLSVGNP RDKIVQEVMR MILDTIFDKK
360 370 380 390 400
MSTHSHGFRK NMSCQTAIWE VRNMFGGSNW FIEVDLKKCF DTISHDLIIK
410 420 430 440 450
ELKRYISDKG FIDLVYKLLR AGYIDEKGTY HKPMLGLPQG SLISPILCNI
460 470 480 490 500
VMTLVDNWLE DYINLYNKGK VKKQHPTYKK LSRMIAKAKM FSTRLKLHKE
510 520 530 540 550
RAKGPTFIYN DPNFKRMKYV RYADDILIGV LGSKNDCKMI KRDLNNFLNS
560 570 580 590 600
LGLTMNEEKT LITCATETPA RFLGYNISIT PLKRMPTVTK TIRGKTIRSR
610 620 630 640 650
NTTRPIINAP IRDIINKLAT NGYCKHNKNG RMGVPTRVGR WTYEEPRTII
660 670 680 690 700
NNYKALGRGI LNYYKLATNY KRLRERIYYV LYYSCVLTLA SKYRLKTMSK
710 720 730 740 750
TIKKFGYNLN IIENDKLIAN FPRNTFDNIK KIENHGMFMY MSEAKVTDPF
760 770 780 790 800
EYIDSIKYML PTAKANFNKP CSICNSTIDV EMHHVKQLHR GMLKATKDYI
810 820 830
TGRMITMNRK QIPLCKQCHI KTHKNKFKNM GPGM
Length:834
Mass (Da):96,079
Last modified:December 20, 2005 - v2
Checksum:iBFB64B6F36416A5A
GO

Sequence cautioni

The sequence CAA24071 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti118F → N (PubMed:6254986).Curated1
Sequence conflicti118F → N (PubMed:3549452).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00694 Genomic DNA Translation: CAA24071.1 Different initiation.
L36897 Genomic DNA Translation: AAA67532.1
KP263414 Genomic DNA Translation: AIZ98886.1
PIRiA04508 QXBY31
S78642
RefSeqiNP_009310.1, NC_001224.1

Genome annotation databases

EnsemblFungiiQ0050; Q0050; Q0050
GeneIDi854593
KEGGisce:Q0050

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00694 Genomic DNA Translation: CAA24071.1 Different initiation.
L36897 Genomic DNA Translation: AAA67532.1
KP263414 Genomic DNA Translation: AIZ98886.1
PIRiA04508 QXBY31
S78642
RefSeqiNP_009310.1, NC_001224.1

3D structure databases

ProteinModelPortaliP03875
SMRiP03875
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34785, 7 interactors
DIPiDIP-8242N
IntActiP03875, 1 interactor
MINTiP03875
STRINGi4932.Q0050

Protein family/group databases

REBASEi2622 I-SceIII

Proteomic databases

MaxQBiP03875
PaxDbiP03875
PRIDEiP03875

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiQ0050; Q0050; Q0050
GeneIDi854593
KEGGisce:Q0050

Organism-specific databases

SGDiS000007261 AI1

Phylogenomic databases

GeneTreeiENSGT00840000130858
HOGENOMiHOG000172601
InParanoidiP03875
OMAiTYQQEYR
OrthoDBiEOG092C47G1

Enzyme and pathway databases

BioCyciYEAST:G3O-34372-MONOMER

Miscellaneous databases

PROiPR:P03875

Family and domain databases

CDDicd00085 HNHc, 1 hit
Gene3Di1.20.210.10, 1 hit
InterProiView protein in InterPro
IPR036927 Cyt_c_oxase-like_su1_sf
IPR024937 Domain_X
IPR003615 HNH_nuc
IPR000477 RT_dom
PfamiView protein in Pfam
PF01348 Intron_maturas2, 1 hit
PF00078 RVT_1, 1 hit
SMARTiView protein in SMART
SM00507 HNHc, 1 hit
SUPFAMiSSF81442 SSF81442, 1 hit
PROSITEiView protein in PROSITE
PS50878 RT_POL, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiAI1M_YEAST
AccessioniPrimary (citable) accession number: P03875
Secondary accession number(s): A0A0A7NYG1, Q9ZZX5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: December 20, 2005
Last modified: November 7, 2018
This is version 148 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
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Main funding by: National Institutes of Health

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