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Protein

Putative racemase YgeA

Gene

ygeA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • amino-acid racemase activity Source: EcoCyc

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIsomerase

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

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BioCyci
EcoCyc:EG11157-MONOMER
MetaCyc:EG11157-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative racemase YgeA (EC:5.-.-.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ygeA
Ordered Locus Names:b2840, JW2808
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

Escherichia coli strain K12 genome database

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EcoGenei
EG11157 ygeA

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000955371 – 230Putative racemase YgeAAdd BLAST230

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
P03813

PRoteomics IDEntifications database

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PRIDEi
P03813

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
nudGP777882EBI-545190,EBI-545184

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
4262310, 16 interactors

Database of interacting proteins

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DIPi
DIP-12147N

Protein interaction database and analysis system

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IntActi
P03813, 2 interactors

STRING: functional protein association networks

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STRINGi
316385.ECDH10B_3012

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
P03813

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P03813

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG4105CG9 Bacteria
COG1794 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000262146

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P03813

Database for complete collections of gene phylogenies

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PhylomeDBi
P03813

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR015942 Asp/Glu/hydantoin_racemase
IPR001920 Asp/Glu_race
IPR018187 Asp/Glu_racemase_AS_1
IPR033134 Asp/Glu_racemase_AS_2
IPR004380 Asp_race

The PANTHER Classification System

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PANTHERi
PTHR21198:SF7 PTHR21198:SF7, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF01177 Asp_Glu_race, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF53681 SSF53681, 2 hits

TIGRFAMs; a protein family database

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TIGRFAMsi
TIGR00035 asp_race, 1 hit

PROSITE; a protein domain and family database

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PROSITEi
View protein in PROSITE
PS00923 ASP_GLU_RACEMASE_1, 1 hit
PS00924 ASP_GLU_RACEMASE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P03813-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKTIGLLGGM SWESTIPYYR LINEGIKQRL GGLHSAQVLL HSVDFHEIEE
60 70 80 90 100
CQRRGEWDKT GDILAEAALG LQRAGAEGIV LCTNTMHKVA DAIESRCTLP
110 120 130 140 150
FLHIADATGR AITGAGMTRV ALLGTRYTME QDFYRGRLTE QFSINCLIPE
160 170 180 190 200
ADERAKINQI IFEELCLGQF TEASRAYCAQ VIARLAEQGA QGVIFGCTEI
210 220 230
GLLVPEERSV LPVFDTAAIH AEDAVAFMLS
Length:230
Mass (Da):25,248
Last modified:July 21, 1986 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i370E9549BD37FF61
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
J03732 Genomic DNA Translation: AAA23470.1
J01614 Genomic DNA Translation: AAA83863.1
U29581 Genomic DNA Translation: AAB40487.1
U00096 Genomic DNA Translation: AAC75879.1
AP009048 Genomic DNA Translation: BAE76909.1

Protein sequence database of the Protein Information Resource

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PIRi
A04438 QQECK

NCBI Reference Sequences

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RefSeqi
NP_417317.1, NC_000913.3
WP_000848659.1, NZ_LN832404.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC75879; AAC75879; b2840
BAE76909; BAE76909; BAE76909

Database of genes from NCBI RefSeq genomes

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GeneIDi
947348

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
ecj:JW2808
eco:b2840

Pathosystems Resource Integration Center (PATRIC)

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PATRICi
fig|511145.12.peg.2938

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J03732 Genomic DNA Translation: AAA23470.1
J01614 Genomic DNA Translation: AAA83863.1
U29581 Genomic DNA Translation: AAB40487.1
U00096 Genomic DNA Translation: AAC75879.1
AP009048 Genomic DNA Translation: BAE76909.1
PIRiA04438 QQECK
RefSeqiNP_417317.1, NC_000913.3
WP_000848659.1, NZ_LN832404.1

3D structure databases

ProteinModelPortaliP03813
SMRiP03813
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262310, 16 interactors
DIPiDIP-12147N
IntActiP03813, 2 interactors
STRINGi316385.ECDH10B_3012

Proteomic databases

PaxDbiP03813
PRIDEiP03813

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75879; AAC75879; b2840
BAE76909; BAE76909; BAE76909
GeneIDi947348
KEGGiecj:JW2808
eco:b2840
PATRICifig|511145.12.peg.2938

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB1146
EcoGeneiEG11157 ygeA

Phylogenomic databases

eggNOGiENOG4105CG9 Bacteria
COG1794 LUCA
HOGENOMiHOG000262146
InParanoidiP03813
PhylomeDBiP03813

Enzyme and pathway databases

BioCyciEcoCyc:EG11157-MONOMER
MetaCyc:EG11157-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P03813

Family and domain databases

InterProiView protein in InterPro
IPR015942 Asp/Glu/hydantoin_racemase
IPR001920 Asp/Glu_race
IPR018187 Asp/Glu_racemase_AS_1
IPR033134 Asp/Glu_racemase_AS_2
IPR004380 Asp_race
PANTHERiPTHR21198:SF7 PTHR21198:SF7, 1 hit
PfamiView protein in Pfam
PF01177 Asp_Glu_race, 1 hit
SUPFAMiSSF53681 SSF53681, 2 hits
TIGRFAMsiTIGR00035 asp_race, 1 hit
PROSITEiView protein in PROSITE
PS00923 ASP_GLU_RACEMASE_1, 1 hit
PS00924 ASP_GLU_RACEMASE_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYGEA_ECOLI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P03813
Secondary accession number(s): Q2M9Z7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: November 7, 2018
This is version 136 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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