Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Major spike protein G

Gene

G

Organism
Enterobacteria phage phiX174 (Isolate Sanger) (Bacteriophage phi-X174)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Attaches the circulating virion to the bacterial lipopolysaccharides which serve as receptor for the virus. Determines the phage host-range. Probably triggers with protein H the injection of the phage DNA into the host cytoplasm upon conformational changes induced by the interaction with host lipopolysaccharides.2 Publications

GO - Biological processi

Keywordsi

Biological processHost-virus interaction, Viral attachment to host cell, Viral genome ejection through host cell envelope, Viral penetration into host cytoplasm, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Major spike protein G
Alternative name(s):
G protein
GPG
Gene namesi
Name:G
OrganismiEnterobacteria phage phiX174 (Isolate Sanger) (Bacteriophage phi-X174)
Taxonomic identifieri1217068 [NCBI]
Taxonomic lineageiVirusesssDNA virusesMicroviridaeBullavirinaePhix174microvirus
Virus hostiEscherichia coli C [TaxID: 498388]
Proteomesi
  • UP000005893 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Capsid protein, Host cytoplasm, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001648951 – 175Major spike protein GAdd BLAST175

Interactioni

Subunit structurei

Pentamerizes and interacts with H protein, F and B pentamers to form 12S pre-assembly complex. Joining of twelve 12S complex form the procapsid.

Protein-protein interaction databases

DIPiDIP-6199N
IntActiP03643, 1 interactor

Structurei

Secondary structure

1175
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi13 – 17Combined sources5
Beta strandi26 – 28Combined sources3
Beta strandi30 – 33Combined sources4
Beta strandi36 – 49Combined sources14
Beta strandi51 – 61Combined sources11
Beta strandi69 – 83Combined sources15
Beta strandi88 – 98Combined sources11
Beta strandi108 – 110Combined sources3
Beta strandi115 – 117Combined sources3
Beta strandi120 – 130Combined sources11
Beta strandi134 – 137Combined sources4
Beta strandi139 – 150Combined sources12
Beta strandi152 – 163Combined sources12

3D structure databases

ProteinModelPortaliP03643
SMRiP03643
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP03643

Family & Domainsi

Sequence similaritiesi

Belongs to the microvirus G protein family.Curated

Phylogenomic databases

OrthoDBiVOG090000UM

Family and domain databases

Gene3Di2.60.120.20, 1 hit
InterProiView protein in InterPro
IPR016184 Capsid/spike_ssDNA_virus
IPR003515 Spike_G
IPR029053 Viral_coat
PfamiView protein in Pfam
PF02306 Phage_G, 1 hit
PIRSFiPIRSF004159 Spike_G, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD013365 Spike_G, 1 hit
SUPFAMiSSF88645 SSF88645, 1 hit

Sequencei

Sequence statusi: Complete.

P03643-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFQTFISRHN SNFFSDKLVL TSVTPASSAP VLQTPKATSS TLYFDSLTVN
60 70 80 90 100
AGNGGFLHCI QMDTSVNAAN QVVSVGADIA FDADPKFFAC LVRFESSSVP
110 120 130 140 150
TTLPTAYDVY PLNGRHDGGY YTVKDCVTID VLPRTPGNNV YVGFMVWSNF
160 170
TATKCRGLVS LNQVIKEIIC LQPLK
Length:175
Mass (Da):19,047
Last modified:July 21, 1986 - v1
Checksum:iAA2418CD82666A7C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J02482 Genomic DNA Translation: AAA32579.1
PIRiC93185 ZGBPF4

Similar proteinsi

Entry informationi

Entry nameiG_BPPHS
AccessioniPrimary (citable) accession number: P03643
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: March 28, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health