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Entry version 129 (07 Oct 2020)
Sequence version 1 (21 Jul 1986)
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Protein

RNA1 polyprotein

Gene
N/A
Organism
Cowpea mosaic virus (strain SB) (CPMV)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Thiol protease that cleaves the RNA1 and RNA2 polyproteins.3 Publications
Plays a role in RNA replication. It is covalently linked to the 5'terminus of both viral single-stranded RNA1 and RNA2 molecules.2 Publications
Down-regulates the RNA1 polyprotein processing and enhances trans-cleavage of RNA2 polyproteins (PubMed:1413528). The protease cofactor and the putative helicase seem to target the replication complexes to ER membranes. Their physical association causes the membrane rearrangement of host ER that may result in formation of the small membranous vesicles that are the site of viral RNA synthesis (PubMed:12021362).2 Publications
The protease cofactor and the putative helicase seem to target the replication complexes to ER membranes. Their physical association causes the membrane rearrangement of host ER that may result in formation of the small membranous vesicles that are the site of viral RNA synthesis.1 Publication
Replicates the viral genome.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei987For picornain 3C-like protease activityPROSITE-ProRule annotation1 Publication1
Active sitei1023For picornain 3C-like protease activityPROSITE-ProRule annotation1 Publication1
Active sitei1113For picornain 3C-like protease activityPROSITE-ProRule annotation1 Publication1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi494 – 501ATPPROSITE-ProRule annotation1 Publication8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHelicase, Hydrolase, Nucleotidyltransferase, Protease, RNA-directed RNA polymerase, Thiol protease, Transferase
Biological processViral RNA replication
LigandATP-binding, Nucleotide-binding

Protein family/group databases

MEROPS protease database

More...
MEROPSi
C03.003

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RNA1 polyprotein
Alternative name(s):
B RNA polyprotein
Bottom component polyprotein
Genome polyprotein B
P1
Cleaved into the following 5 chains:
Alternative name(s):
32 kDa protein
Putative helicase (EC:3.6.4.-)
Alternative name(s):
58 kDa protein
Membrane-binding protein
NTP-binding protein
Short name:
NTB
Alternative name(s):
VPg
Picornain 3C-like protease (EC:3.4.22.-1 Publication)
Short name:
3C-like protease
Alternative name(s):
24 kDa protein
RNA-directed RNA polymerasePROSITE-ProRule annotation (EC:2.7.7.48PROSITE-ProRule annotation1 Publication)
Alternative name(s):
87 kDa protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCowpea mosaic virus (strain SB) (CPMV)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri928299 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesRiboviriaOrthornaviraePisuviricotaPisoniviricetesPicornaviralesSecoviridaeComovirinaeComovirus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiCajanus cajan (Pigeon pea) (Cajanus indicus) [TaxID: 3821]
Crotalaria juncea (Sunn hemp) [TaxID: 3829]
Vigna unguiculata (Cowpea) [TaxID: 3917]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei897 – 917HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasm, Host endoplasmic reticulum, Host membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi500K → T: Complete loss of viral replication; reduced ATP-binding by the RNA-directed RNA polymerase; no effect on polyprotein processing. 1 Publication1
Mutagenesisi545D → P: Complete loss of viral replication; no effect on polyprotein processing. 1 Publication1
Mutagenesisi920 – 922SRK → GRS: Increased efficiency of cleavage between the putative helicase and VPg. Complete loss of infectivity. 1 Publication3
Mutagenesisi920 – 921SR → YG: Slightly decreased efficiency of cleavage between the putative helicase and VPg. Complete loss of infectivity. 2
Mutagenesisi920S → T: Decreased efficiency of cleavage between the putative helicase and VPg. Complete loss of infectivity. 1
Mutagenesisi928 – 929MQ → VA: No effect on infectivity. 1 Publication2
Mutagenesisi934 – 936NNV → RNI: 80% decrease of infectivity. 1 Publication3
Mutagenesisi939 – 942KRRV → RKRN: Complete loss of infectivity. 1 Publication4
Mutagenesisi945 – 946DA → EG: 50% decrease of infectivity. Replicative proteins display a uniform cytoplasmic distribution, instead of the normal accumulation near the nucleus. 1 Publication2
Mutagenesisi947Q → H: Strongly decreased efficiency of cleavage between VPg and 3C-like protease. Complete loss of infectivity. 1 Publication1
Mutagenesisi1113C → S: Reduced protease activity. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved1 Publication
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004458342 – 1866RNA1 polyproteinAdd BLAST1865
ChainiPRO_00000370062 – 326Protease cofactorAdd BLAST325
ChainiPRO_0000037007327 – 919Putative helicaseAdd BLAST593
ChainiPRO_0000037008920 – 947Viral genome-linked proteinAdd BLAST28
ChainiPRO_0000037009948 – 1155Picornain 3C-like proteaseAdd BLAST208
ChainiPRO_00000370101156 – 1866RNA-directed RNA polymeraseAdd BLAST711

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei920O-(5'-phospho-RNA)-serine1 Publication1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Specific enzymatic cleavages by picornain 3C-like protease in vivo yield mature proteins (PubMed:16789216, PubMed:16789257, PubMed:7964626, PubMed:1431806). Picornain 3C-like protease is autocatalytically processed.4 Publications
Uridylylated by the polymerase and is covalently linked to the 5'-end of genomic RNA. This uridylylated form acts as a nucleotide-peptide primer for the polymerase.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei326 – 327Cleavage; by viral protease1 Publication2
Sitei919 – 920Cleavage; by viral protease1 Publication2
Sitei947 – 948Cleavage; by viral protease1 Publication2
Sitei1155 – 1156Cleavage; by viral protease1 Publication2

Keywords - PTMi

Covalent protein-RNA linkage, Phosphoprotein

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
P03600

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Biological Magnetic Resonance Data Bank

More...
BMRBi
P03600

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini462 – 633SF3 helicasePROSITE-ProRule annotationAdd BLAST172
Domaini945 – 1150Peptidase C3PROSITE-ProRule annotationAdd BLAST206
Domaini1429 – 1559RdRp catalyticPROSITE-ProRule annotationAdd BLAST131

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.10.10, 1 hit
3.30.70.270, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR004004, Helic/Pol/Pept_Calicivir-typ
IPR000605, Helicase_SF3_ssDNA/RNA_vir
IPR014759, Helicase_SF3_ssRNA_vir
IPR000199, Peptidase_C3A/C3B_picornavir
IPR009003, Peptidase_S1_PA
IPR043504, Peptidase_S1_PA_chymotrypsin
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR001205, RNA-dir_pol_C
IPR007094, RNA-dir_pol_PSvirus

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00548, Peptidase_C3, 1 hit
PF00680, RdRP_1, 1 hit
PF00910, RNA_helicase, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00918, CALICVIRUSNS

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50494, SSF50494, 1 hit
SSF56672, SSF56672, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51874, PCV_3C_PRO, 1 hit
PS50507, RDRP_SSRNA_POS, 1 hit
PS51218, SF3_HELICASE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P03600-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGLPEYEADS EALLSQLTIE FTPGMTVSSL LAQVTTNDFH SAIEFFAAEK
60 70 80 90 100
AVDIEGVHYN AYMQQIRKNP SLLRISVVAY AFHVSDMVAE TMSYDVYEFL
110 120 130 140 150
YKHYALFISN LVTRTLRFKE LLLFCKQQFL EKMQASIVWA PELEQYLQVE
160 170 180 190 200
GDAVAQGVSQ LLYKMVTWVP TFVRGAVDWS VDAILVSFRK HFEKMVQEYV
210 220 230 240 250
PMAHRVCSWL SQLWDKIVQW ISQASETMGW FLDGCRDLMT WGIATLATCS
260 270 280 290 300
ALSLVEKLLV AMGFLVEPFG LSGIFLRTGV VAAACYNYGT NSKGFAEMMA
310 320 330 340 350
LLSLAANCVS TVIVGGFFPG EKDNAQSSPV ILLEGLAGQM QNFCETTLVS
360 370 380 390 400
VGKTCTAVNA ISTCCGNLKA LAGRILGMLR DFIWKTLGFE TRFLADASLL
410 420 430 440 450
FGEDVDGWLK AISDLRDQFI AKSYCSQDEM MQILVLLEKG RQMRKSGLSK
460 470 480 490 500
GGISPAIINL ILKGINDLEQ LNRSCSVQGV RGVRKMPFTI FFQGKSRTGK
510 520 530 540 550
SLLMSQVTKD FQDHYGLGGE TVYSRNPCDQ YWSGYRRQPF VLMDDFAAVV
560 570 580 590 600
TEPSAEAQMI NLISSAPYPL NMAGLEEKGI CFDSQFVFVS TNFLEVSPEA
610 620 630 640 650
KVRDDEAFKN RRHVIVQVSN DPAKAYDAAN FASNQIYTIL AWKDGRYNTV
660 670 680 690 700
CVIEDYDELV AYLLTRSQQH AEEQEKNLAN MMKSATFESH FKSLVEVLEL
710 720 730 740 750
GSMISAGFDI IRPEKLPSEA KEKRVLYSIP YNGEYCNALI DDNYNVTCWF
760 770 780 790 800
GECVGNPEQL SKYSEKMLLG AYEFLLCSES LNVVIQAHLK EMVCPHHYDK
810 820 830 840 850
ELNFIGKIGE TYYHNQMVSN IGSMQKWHRA ILFGIGVLLG KEKEKTWYQV
860 870 880 890 900
QVANVKQALY DMYTKEIRDW PMPIKVTCGI VLAAIGGSAF WKVFQQLVGS
910 920 930 940 950
GNGPVLMGVA AGAFSAEPQS RKPNRFDMQQ YRYNNVPLKR RVWADAQMSL
960 970 980 990 1000
DQSSVAIMSK CRANLVFGGT NLQIVMVPGR RFLACKHFFT HIKTKLRVEI
1010 1020 1030 1040 1050
VMDGRRYYHQ FDPANIYDIP DSELVLYSHP SLEDVSHSCW DLFCWDPDKE
1060 1070 1080 1090 1100
LPSVFGADFL SCKYNKFGGF YEAQYADIKV RTKKECLTIQ SGNYVNKVSR
1110 1120 1130 1140 1150
YLEYEAPTIP EDCGSLVIAH IGGKHKIVGV HVAGIQGKIG CASLLPPLEP
1160 1170 1180 1190 1200
IAQAQGAEEY FDFLPAEENV SSGVAMVAGL KQGVYIPLPT KTALVETPSE
1210 1220 1230 1240 1250
WHLDTPCDKV PSILVPTDPR IPAQHEGYDP AKSGVSKYSQ PMSALDPELL
1260 1270 1280 1290 1300
GEVANDVLEL WHDCAVDWDD FGEVSLEEAL NGCEGVEYME RIPLATSEGF
1310 1320 1330 1340 1350
PHILSRNGKE KGKRRFVQGD DCVVSLIPGT TVAKAYEELE ASAHRFVPAL
1360 1370 1380 1390 1400
VGIECPKDEK LPMRKVFDKP KTRCFTILPM EYNLVVRRKF LNFVRFIMAN
1410 1420 1430 1440 1450
RHRLSCQVGI NPYSMEWSRL AARMKEKGND VLCCDYSSFD GLLSKQVMDV
1460 1470 1480 1490 1500
IASMINELCG GEDQLKNARR NLLMACCSRL AICKNTVWRV ECGIPSGFPM
1510 1520 1530 1540 1550
TVIVNSIFNE ILIRYHYKKL MREQQAPELM VQSFDKLIGL VTYGDDNLIS
1560 1570 1580 1590 1600
VNAVVTPYFD GKKLKQSLAQ GGVTITDGKD KTSLELPFRR LEECDFLKRT
1610 1620 1630 1640 1650
FVQRSSTIWD APEDKASLWS QLHYVNCNNC EKEVAYLTNV VNVLRELYMH
1660 1670 1680 1690 1700
SPREATEFRR KVLKKVSWIT SGDLPTLAQL QEFYEYQRQQ GGADNNDTCD
1710 1720 1730 1740 1750
LLTSVDLLGP PLSFEKEAMH GCKVSEEIVT KNLAYYDFKR KGEDEVVFLF
1760 1770 1780 1790 1800
NTLYPQSSLP DGCHSVTWSQ GSGRGGLPTQ SWMSYNISRK DSNINKIIRT
1810 1820 1830 1840 1850
AVSSKKRVIF CARDNMVPVN IVALLCAVRN KLMPTAVSNA TLVKVMENAK
1860
AFKFLPEEFN FAFSDV
Length:1,866
Mass (Da):209,810
Last modified:July 21, 1986 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0D4CD8A11C0B2976
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X00206 Genomic RNA Translation: CAA25029.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A04211, GNWE2C

NCBI Reference Sequences

More...
RefSeqi
NP_613283.1, NC_003549.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
956628

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
vg:956628

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X00206 Genomic RNA Translation: CAA25029.1
PIRiA04211, GNWE2C
RefSeqiNP_613283.1, NC_003549.1

3D structure databases

BMRBiP03600
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...

Protein family/group databases

MEROPSiC03.003

Proteomic databases

PRIDEiP03600

Genome annotation databases

GeneIDi956628
KEGGivg:956628

Family and domain databases

Gene3Di2.40.10.10, 1 hit
3.30.70.270, 1 hit
InterProiView protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR004004, Helic/Pol/Pept_Calicivir-typ
IPR000605, Helicase_SF3_ssDNA/RNA_vir
IPR014759, Helicase_SF3_ssRNA_vir
IPR000199, Peptidase_C3A/C3B_picornavir
IPR009003, Peptidase_S1_PA
IPR043504, Peptidase_S1_PA_chymotrypsin
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR001205, RNA-dir_pol_C
IPR007094, RNA-dir_pol_PSvirus
PfamiView protein in Pfam
PF00548, Peptidase_C3, 1 hit
PF00680, RdRP_1, 1 hit
PF00910, RNA_helicase, 1 hit
PRINTSiPR00918, CALICVIRUSNS
SUPFAMiSSF50494, SSF50494, 1 hit
SSF56672, SSF56672, 1 hit
PROSITEiView protein in PROSITE
PS51874, PCV_3C_PRO, 1 hit
PS50507, RDRP_SSRNA_POS, 1 hit
PS51218, SF3_HELICASE_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPOL1_CPMVS
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P03600
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: October 7, 2020
This is version 129 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome
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