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Protein

Major capsid protein VP1

Gene
N/A
Organism
JC polyomavirus (JCPyV) (JCV)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Forms an icosahedral capsid with a T=7 symmetry and a 40 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins. Interacts with a N-linked glycoprotein containing terminal alpha2-6-linked sialic acids on the cell surface to provide virion attachment to target cell. The serotonergic receptor 5HT2AR also acts as a cellular receptor for JCV on human glial cells. Once attached, the virions enter predominantly by a ligand-inducible clathrin-dependent pathway and traffic to the ER. Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating. Next, the virion uses the endoplasmic reticulum-associated degradation machinery to probably translocate in the cytosol before reaching the nucleus. Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2/Vp3 nuclear localization signal. In late phase of infection, neo-synthesized VP1 encapsulates replicated genomic DNA at nuclear domains called promyelocytic leukemia (PML) bodies, and participates in rearranging nucleosomes around the viral DNA.1 Publication2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processClathrin-mediated endocytosis of virus by host, Host-virus interaction, Viral attachment to host cell, Viral penetration into host cytoplasm, Virus endocytosis by host, Virus entry into host cell

Protein family/group databases

UniLectin database of carbohydrate-binding proteins

More...
UniLectini
P03089

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Major capsid protein VP1
Alternative name(s):
Major structural protein VP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiJC polyomavirus (JCPyV) (JCV)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10632 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePolyomaviridae
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiHomo sapiens (Human) [TaxID: 9606]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008478 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Capsid protein, Host nucleus, T=7 icosahedral capsid protein, Virion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001150211 – 354Major capsid protein VP1Add BLAST354

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi97Interchain (with C-97)By similarity
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei330Phosphothreonine; by hostBy similarity1

Keywords - PTMi

Disulfide bond, Phosphoprotein

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Keywords - Developmental stagei

Late protein

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homomultimer; disulfide-linked. The virus capsid is composed of 72 icosahedral units, each one composed of five disulfide-linked copies of VP1. Interacts with minor capsid proteins VP2 and VP3 (By similarity). Interacts with host 5HT2AR.By similarity2 Publications

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1354
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
P03089

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P03089

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P03089

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni294 – 354Intrinsically disorderedBy similarityAdd BLAST61

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The intrinsically disordered C-terminal region interacts with neighboring pentamers. The unstructured nature of this region allows to make different interactions depending on the structural context: pentamers present at the 12 icosahedral fivefold axes bind five pentamers, when pentamers present at the 60 icosahedral six-fold axes interacts with six pentamers.By similarity

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

KEGG Orthology (KO)

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KOi
K19248

Database of Orthologous Groups

More...
OrthoDBi
VOG090000AE

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.175.10, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR000662 Capsid_VP1_Polyomavir
IPR011222 dsDNA_vir_gr_I_capsid
IPR036931 Polyomavir_VP1_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00718 Polyoma_coat, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF003376 Capsid_VP1_Polyomavir, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF88648 SSF88648, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing and alternative initiation. AlignAdd to basket
Isoform VP1 (identifier: P03089-1) [UniParc]FASTAAdd to basket
Also known as: Major capsid protein VP1

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAPTKRKGER KDPVQVPKLL IRGGVEVLEV KTGVDSITEV ECFLTPEMGD
60 70 80 90 100
PDEHLRGFSK SISISDTFES DSPNRDMLPC YSVARIPLPN LNEDLTCGNI
110 120 130 140 150
LMWEAVTLKT EVIGVTSLMN VHSNGQATHD NGAGKPVQGT SFHFFSVGGE
160 170 180 190 200
ALELQGVLFN YRTKYPDGTI FPKNATVQSQ VMNTEHKAYL DKNKAYPVEC
210 220 230 240 250
WVPDPTRNEN TRYFGTLTGG ENVPPVLHIT NTATTVLLDE FGVGPLCKGD
260 270 280 290 300
NLYLSAVDVC GMFTNRSGSQ QWRGLSRYFK VQLRKRRVKN PYPISFLLTD
310 320 330 340 350
LINRRTPRVD GQPMYGMDAQ VEEVRVFEGT EELPGDPDMM RYVDKYGQLQ

TKML
Note: Produced by alternative splicing of the late mRNA.
Length:354
Mass (Da):39,609
Last modified:July 21, 1986 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i33CDA3DD93026ED0
GO
Isoform VP2 (identifier: P03095-1) [UniParc]FASTAAdd to basket
Also known as: Minor capsid protein VP2
The sequence of this isoform can be found in the external entry P03095.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Produced by alternative splicing of the late mRNA.
Length:344
Mass (Da):37,368
GO
Isoform VP3 (identifier: P03095-2) [UniParc]FASTAAdd to basket
Also known as: Minor capsid protein VP3
The sequence of this isoform can be found in the external entry P03095.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Produced by alternative initiation at Met-120 of isoform VP2.
Length:225
Mass (Da):25,745
GO
Isoform VP4 (identifier: P03095-3) [UniParc]FASTAAdd to basket
Also known as: Viroporin VP4
The sequence of this isoform can be found in the external entry P03095.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Produced by alternative initiation at Met-229 of isoform VP2.
Length:116
Mass (Da):12,988
GO
Isoform Agno (identifier: P03086-1) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry P03086.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Produced by alternative initiation of the late mRNA.
Length:71
Mass (Da):8,081
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti66D → H in strain: Isolate MAD11-BR. 1
Natural varianti74N → S in strain: Isolate NY-1B, Isolate N1 and Isolate G3. 1
Natural varianti75R → K in strain: Isolate YI, Isolate TKY-2A, Isolate MAD8-BR, Isolate HER1-BR, Isolate NY-1B, Isolate N1, Isolate N4, Isolate G3, Isolate C1, Isolate CY, Isolate MY, Isolate AIC-1A and Isolate Tokyo-1. 1
Natural varianti113I → L in strain: Isolate YI, Isolate C1, Isolate AIC-1A and Isolate Tokyo-1. 1
Natural varianti117S → T in strain: Isolate YI, Isolate TKY-2A, Isolate MAD8-BR, Isolate N4, Isolate C1, Isolate CY, Isolate MY, Isolate AIC-1A and Isolate Tokyo-1. 1
Natural varianti128T → A in strain: Isolate MAD8-BR, Isolate NY-1B, Isolate N1, Isolate G3 and Isolate N4. 1
Natural varianti158L → V in strain: Isolate YI, Isolate TKY-2A, Isolate MAD8-BR, Isolate NY-1B, Isolate N1, Isolate N4, Isolate G3, Isolate C1, Isolate CY, Isolate MY, Isolate AIC-1A and Isolate Tokyo-1. 1
Natural varianti267S → L in strain: Isolate HER1-BR. 1
Natural varianti269S → F in strain: Isolate MAD8-BR. 1
Natural varianti269S → T in strain: Isolate YI. 1
Natural varianti269S → Y in strain: Isolate TKY-2A. 1
Natural varianti321V → I in strain: Isolate C1. 1
Natural varianti345K → R in strain: Isolate YI, Isolate TKY-2A, Isolate MAD8-BR, Isolate N1, Isolate N4, Isolate G4, Isolate C1, Isolate CY, Isolate MY, Isolate AIC-1A and Isolate Tokyo-1. 1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
J02226 Genomic DNA Translation: AAA82101.1
D11356 Genomic DNA Translation: BAA01958.1
D11357 Genomic DNA Translation: BAA01959.1
D11358 Genomic DNA Translation: BAA01960.1
D11359 Genomic DNA Translation: BAA01961.1
D11360 Genomic DNA Translation: BAA01962.1
D11361 Genomic DNA Translation: BAA01963.1
D11362 Genomic DNA Translation: BAA01964.1
D11363 Genomic DNA Translation: BAA01965.1
D11364 Genomic DNA Translation: BAA01966.1
D11365 Genomic DNA Translation: BAA01967.1
D11366 Genomic DNA Translation: BAA01968.1
D11368 Genomic DNA Translation: BAA01970.1
D26589 Genomic DNA Translation: BAA05636.1
D26591 Genomic DNA Translation: BAA05638.1
D26592 Genomic DNA Translation: BAA05639.1

Protein sequence database of the Protein Information Resource

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PIRi
A03626 VVVP1J

NCBI Reference Sequences

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RefSeqi
NP_043511.1, NC_001699.1 [P03089-1]

Genome annotation databases

Database of genes from NCBI RefSeq genomes

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GeneIDi
1489518

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
vg:1489518

Keywords - Coding sequence diversityi

Alternative initiation, Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J02226 Genomic DNA Translation: AAA82101.1
D11356 Genomic DNA Translation: BAA01958.1
D11357 Genomic DNA Translation: BAA01959.1
D11358 Genomic DNA Translation: BAA01960.1
D11359 Genomic DNA Translation: BAA01961.1
D11360 Genomic DNA Translation: BAA01962.1
D11361 Genomic DNA Translation: BAA01963.1
D11362 Genomic DNA Translation: BAA01964.1
D11363 Genomic DNA Translation: BAA01965.1
D11364 Genomic DNA Translation: BAA01966.1
D11365 Genomic DNA Translation: BAA01967.1
D11366 Genomic DNA Translation: BAA01968.1
D11368 Genomic DNA Translation: BAA01970.1
D26589 Genomic DNA Translation: BAA05636.1
D26591 Genomic DNA Translation: BAA05638.1
D26592 Genomic DNA Translation: BAA05639.1
PIRiA03626 VVVP1J
RefSeqiNP_043511.1, NC_001699.1 [P03089-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3NXDX-ray2.00A/B/C/D/E23-290[»]
3NXGX-ray1.95A/B/C/D/E23-290[»]
4JCDX-ray2.00A/B/C/D/E23-290[»]
4JCEX-ray1.90A/B/C/D/E23-290[»]
4JCFX-ray2.20A/B/C/D/E23-290[»]
4WDYX-ray1.90A/B/C/D/E23-290[»]
4WDZX-ray1.80A/B/C/D/E23-290[»]
4WE0X-ray2.10A/B/C/D/E23-290[»]
4X14X-ray2.30A/B/C/D/E23-290[»]
4X15X-ray2.11A/B/C/D/E23-290[»]
4X16X-ray1.80A/B/C/D/E23-290[»]
4X17X-ray1.75A/B/C/D/E23-290[»]
ProteinModelPortaliP03089
SMRiP03089
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

UniLectiniP03089

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1489518
KEGGivg:1489518

Phylogenomic databases

KOiK19248
OrthoDBiVOG090000AE

Miscellaneous databases

EvolutionaryTraceiP03089

Family and domain databases

Gene3Di2.60.175.10, 1 hit
InterProiView protein in InterPro
IPR000662 Capsid_VP1_Polyomavir
IPR011222 dsDNA_vir_gr_I_capsid
IPR036931 Polyomavir_VP1_sf
PfamiView protein in Pfam
PF00718 Polyoma_coat, 1 hit
PIRSFiPIRSF003376 Capsid_VP1_Polyomavir, 1 hit
SUPFAMiSSF88648 SSF88648, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiVP1_POVJC
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P03089
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: December 5, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
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