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UniProtKB - P03013 (HIN_SALTY)
Protein
DNA-invertase hin
Gene
hin
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Functioni
A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB. The orientation of the inversion region controls expression of fljB. The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 10 | O-(5'-phospho-DNA)-serine intermediatePROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 162 – 181 | H-T-H motifAdd BLAST | 20 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- DNA strand exchange activity Source: GO_Central
GO - Biological processi
- DNA integration Source: UniProtKB-KW
- DNA recombination Source: GO_Central
Keywordsi
Molecular function | DNA invertase, DNA-binding |
Biological process | DNA integration, DNA recombination |
Names & Taxonomyi
Protein namesi | Recommended name: DNA-invertase hin |
Gene namesi | Name:hin Ordered Locus Names:STM2772 |
Organismi | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) |
Taxonomic identifieri | 99287 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Salmonella › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000196359 | 1 – 190 | DNA-invertase hinAdd BLAST | 190 |
Proteomic databases
PaxDbi | P03013 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P03013 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P03013 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 2 – 135 | Resolvase/invertase-type recombinase catalyticPROSITE-ProRule annotationAdd BLAST | 134 |
Sequence similaritiesi
Belongs to the site-specific recombinase resolvase family.Curated
Phylogenomic databases
HOGENOMi | CLU_010686_8_0_6 |
OMAi | EQIRFAY |
PhylomeDBi | P03013 |
Family and domain databases
Gene3Di | 3.40.50.1390, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR006118, Recombinase_CS IPR006119, Resolv_N IPR036162, Resolvase-like_N_sf IPR006120, Resolvase_HTH_dom |
Pfami | View protein in Pfam PF02796, HTH_7, 1 hit PF00239, Resolvase, 1 hit |
SMARTi | View protein in SMART SM00857, Resolvase, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit SSF53041, SSF53041, 1 hit |
PROSITEi | View protein in PROSITE PS00397, RECOMBINASES_1, 1 hit PS00398, RECOMBINASES_2, 1 hit PS51736, RECOMBINASES_3, 1 hit |
i Sequence
Sequence statusi: Complete.
P03013-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MATIGYIRVS TIDQNIDLQR NALTSANCDR IFEDRISGKI ANRPGLKRAL
60 70 80 90 100
KYVNKGDTLV VWKLDRLGRS VKNLVALISE LHERGAHFHS LTDSIDTSSA
110 120 130 140 150
MGRFFFHVMS ALAEMERELI VERTLAGLAA ARAQGRLGGR PRAINKHEQE
160 170 180 190
QISRLLEKGH PRQQLAIIFG IGVSTLYRYF PASRIKKRMN
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 184 | R → S (PubMed:6933466).Curated | 1 | |
Sequence conflicti | 184 | R → S (PubMed:6271461).Curated | 1 | |
Sequence conflicti | 184 | R → S (PubMed:6251543).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | J01801 Genomic DNA Translation: AAA27073.1 V01370 Genomic DNA Translation: CAA24654.1 M12292 Genomic DNA Translation: AAA27140.1 AE006468 Genomic DNA Translation: AAL21658.1 |
PIRi | A03544, JWEBT |
RefSeqi | NP_461699.1, NC_003197.2 WP_000190912.1, NC_003197.2 |
Genome annotation databases
EnsemblBacteriai | AAL21658; AAL21658; STM2772 |
GeneIDi | 1254295 |
KEGGi | stm:STM2772 |
PATRICi | fig|99287.12.peg.2924 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | J01801 Genomic DNA Translation: AAA27073.1 V01370 Genomic DNA Translation: CAA24654.1 M12292 Genomic DNA Translation: AAA27140.1 AE006468 Genomic DNA Translation: AAL21658.1 |
PIRi | A03544, JWEBT |
RefSeqi | NP_461699.1, NC_003197.2 WP_000190912.1, NC_003197.2 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1HCR | X-ray | 2.30 | A | 139-190 | [»] | |
1IJW | X-ray | 2.40 | C | 139-190 | [»] | |
1JJ6 | X-ray | 2.30 | C | 139-190 | [»] | |
1JJ8 | X-ray | 2.75 | C | 139-190 | [»] | |
1JKO | X-ray | 2.24 | C | 139-190 | [»] | |
1JKP | X-ray | 2.80 | C | 139-190 | [»] | |
1JKQ | X-ray | 2.86 | C | 139-190 | [»] | |
1JKR | X-ray | 2.28 | C | 139-190 | [»] | |
SMRi | P03013 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 99287.STM2772 |
Proteomic databases
PaxDbi | P03013 |
Genome annotation databases
EnsemblBacteriai | AAL21658; AAL21658; STM2772 |
GeneIDi | 1254295 |
KEGGi | stm:STM2772 |
PATRICi | fig|99287.12.peg.2924 |
Phylogenomic databases
HOGENOMi | CLU_010686_8_0_6 |
OMAi | EQIRFAY |
PhylomeDBi | P03013 |
Miscellaneous databases
EvolutionaryTracei | P03013 |
Family and domain databases
Gene3Di | 3.40.50.1390, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR006118, Recombinase_CS IPR006119, Resolv_N IPR036162, Resolvase-like_N_sf IPR006120, Resolvase_HTH_dom |
Pfami | View protein in Pfam PF02796, HTH_7, 1 hit PF00239, Resolvase, 1 hit |
SMARTi | View protein in SMART SM00857, Resolvase, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit SSF53041, SSF53041, 1 hit |
PROSITEi | View protein in PROSITE PS00397, RECOMBINASES_1, 1 hit PS00398, RECOMBINASES_2, 1 hit PS51736, RECOMBINASES_3, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | HIN_SALTY | |
Accessioni | P03013Primary (citable) accession number: P03013 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 21, 1986 |
Last sequence update: | January 23, 2002 | |
Last modified: | February 23, 2022 | |
This is version 146 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families