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Entry version 171 (31 Jul 2019)
Sequence version 2 (01 Jul 1993)
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Protein

Protein TonB

Gene

tonB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates such as cobalamin, and various iron compounds (such as iron dicitrate, enterochelin, aerobactin, etc.). In the absence of TonB these receptors bind their substrates but do not carry out active transport. TonB also interacts with some colicins and is involved in the energy-dependent, irreversible steps of bacteriophages phi 80 and T1 infection. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Implicated in hydroxy radical-mediated cell death induced by hydroxyurea treatment (PubMed:20005847).1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processBacteriocin transport, Protein transport, Transport

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
EcoCyc:EG11012-MONOMER
ECOL316407:JW5195-MONOMER
MetaCyc:EG11012-MONOMER

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.C.1.1.1 the tonb-exbb-exbd/tola-tolq-tolr outer membrane receptor energizers and stabilizers (tonb/tola) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein TonB
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:tonB
Synonyms:exbA
Ordered Locus Names:b1252, JW5195
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

Escherichia coli strain K12 genome database

More...
EcoGenei
EG11012 tonB

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1 – 32Helical; Signal-anchorCuratedAdd BLAST32
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini33 – 239Periplasmic1 PublicationAdd BLAST207

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Cells missing tonB survive hydroxyurea treatment better than wild-type; further disruption of mazE-mazF and relE-relB yields even better survival (PubMed:20005847).1 Publication

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB02767 3-Hydroxy-Myristic Acid
DB03017 Lauric Acid
DB04147 Lauryl Dimethylamine-N-Oxide
DB08231 MYRISTIC ACID

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001961941 – 239Protein TonBAdd BLAST239

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P02929

PRoteomics IDEntifications database

More...
PRIDEi
P02929

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

2-fold by hydroxyurea treatment.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

Forms a complex with the accessory proteins ExbB and ExbD.

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
4262996, 186 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-1083 Vitamin B12 outer membrane transporter complex
CPX-2843 Ferrichrome outer membrane transporter complex
CPX-3576 Ferric-citrate outer membrane transporter complex
CPX-3577 Ferric-catecholate outer membrane transporter complex
CPX-3578 Ferric-enterobactin outer membrane transporter complex
CPX-3579 Ferric-coprogen outer membrane transporter complex
CPX-3580 fiu outer membrane transporter complex
CPX-3585 Uncharacterized yncD-DHBS outer membrane transporter complex

Database of interacting proteins

More...
DIPi
DIP-48111N

Protein interaction database and analysis system

More...
IntActi
P02929, 7 interactors

STRING: functional protein association networks

More...
STRINGi
511145.b1252

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1239
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P02929

Database of comparative protein structure models

More...
ModBasei
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P02929

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati70 – 711-12
Repeati72 – 731-22
Repeati74 – 751-32
Repeati76 – 771-42
Repeati78 – 791-5; approximate2
Repeati80 – 811-62
Repeati91 – 922-12
Repeati93 – 942-22
Repeati95 – 962-32
Repeati97 – 982-42
Repeati99 – 1002-52
Repeati101 – 1022-62

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni70 – 816 X 2 AA approximate tandem repeats of E-PAdd BLAST12
Regioni91 – 1026 X 2 AA tandem repeats of K-PAdd BLAST12

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TonB family.Curated

Keywords - Domaini

Repeat, Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410822N Bacteria
COG0810 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P02929

KEGG Orthology (KO)

More...
KOi
K03832

Family and domain databases

Database of protein disorder

More...
DisProti
DP00043

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003538 TonB
IPR006260 TonB/TolA_C
IPR037682 TonB_C

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03544 TonB_C, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01374 TONBPROTEIN

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01352 tonB_Cterm, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P02929-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTLDLPRRFP WPTLLSVCIH GAVVAGLLYT SVHQVIELPA PAQPISVTMV
60 70 80 90 100
TPADLEPPQA VQPPPEPVVE PEPEPEPIPE PPKEAPVVIE KPKPKPKPKP
110 120 130 140 150
KPVKKVQEQP KRDVKPVESR PASPFENTAP ARLTSSTATA ATSKPVTSVA
160 170 180 190 200
SGPRALSRNQ PQYPARAQAL RIEGQVKVKF DVTPDGRVDN VQILSAKPAN
210 220 230
MFEREVKNAM RRWRYEPGKP GSGIVVNILF KINGTTEIQ
Length:239
Mass (Da):26,094
Last modified:July 1, 1993 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3B59F39D791AE815
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAB59066 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAB60069 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAB60077 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAB60085 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAB60093 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAB60101 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAB60109 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAB60117 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAB60125 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAB60133 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAB60141 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAB60149 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAB60157 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti51T → A in strain: ECOR 28, ECOR 31, ECOR 37, ECOR 46, ECOR 50, ECOR 52, ECOR 60 and ECOR 71. 1
Natural varianti70E → K in strain: ECOR 31. 1
Natural varianti87V → A in strain: ECOR 37 and ECOR 71. 1
Natural varianti102P → PKP in strain: ECOR 50. 1
Natural varianti107Missing in strain: ECOR 52 and ECOR 60. 1
Natural varianti114V → I in strain: ECOR 28. 1
Natural varianti133L → P in strain: ECOR 16, ECOR 31, ECOR 46, ECOR 50, ECOR 52 and ECOR 60. 1
Natural varianti176V → I in strain: ECOR 60. 1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
K00431 Genomic DNA Translation: AAB59066.1 Different initiation.
U24195 Genomic DNA Translation: AAB60069.1 Different initiation.
U24196 Genomic DNA Translation: AAB60077.1 Different initiation.
U24197 Genomic DNA Translation: AAB60085.1 Different initiation.
U24198 Genomic DNA Translation: AAB60093.1 Different initiation.
U24199 Genomic DNA Translation: AAB60101.1 Different initiation.
U24200 Genomic DNA Translation: AAB60109.1 Different initiation.
U24201 Genomic DNA Translation: AAB60117.1 Different initiation.
U24202 Genomic DNA Translation: AAB60125.1 Different initiation.
U24203 Genomic DNA Translation: AAB60133.1 Different initiation.
U24204 Genomic DNA Translation: AAB60141.1 Different initiation.
U24205 Genomic DNA Translation: AAB60149.1 Different initiation.
U24206 Genomic DNA Translation: AAB60157.1 Different initiation.
U00096 Genomic DNA Translation: AAC74334.1
AP009048 Genomic DNA Translation: BAA14784.2

Protein sequence database of the Protein Information Resource

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PIRi
G64872 BVEC

NCBI Reference Sequences

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RefSeqi
NP_415768.1, NC_000913.3
WP_001360141.1, NZ_SSZK01000031.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC74334; AAC74334; b1252
BAA14784; BAA14784; BAA14784

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
945843

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ecj:JW5195
eco:b1252

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|511145.12.peg.1302

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K00431 Genomic DNA Translation: AAB59066.1 Different initiation.
U24195 Genomic DNA Translation: AAB60069.1 Different initiation.
U24196 Genomic DNA Translation: AAB60077.1 Different initiation.
U24197 Genomic DNA Translation: AAB60085.1 Different initiation.
U24198 Genomic DNA Translation: AAB60093.1 Different initiation.
U24199 Genomic DNA Translation: AAB60101.1 Different initiation.
U24200 Genomic DNA Translation: AAB60109.1 Different initiation.
U24201 Genomic DNA Translation: AAB60117.1 Different initiation.
U24202 Genomic DNA Translation: AAB60125.1 Different initiation.
U24203 Genomic DNA Translation: AAB60133.1 Different initiation.
U24204 Genomic DNA Translation: AAB60141.1 Different initiation.
U24205 Genomic DNA Translation: AAB60149.1 Different initiation.
U24206 Genomic DNA Translation: AAB60157.1 Different initiation.
U00096 Genomic DNA Translation: AAC74334.1
AP009048 Genomic DNA Translation: BAA14784.2
PIRiG64872 BVEC
RefSeqiNP_415768.1, NC_000913.3
WP_001360141.1, NZ_SSZK01000031.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1IHRX-ray1.55A/B164-239[»]
1QXXX-ray2.70A164-239[»]
1U07X-ray1.13A/B150-239[»]
1XX3NMR-A103-239[»]
2GRXX-ray3.30C/D31-239[»]
2GSKX-ray2.10B153-233[»]
SMRiP02929
ModBaseiSearch...

Protein-protein interaction databases

BioGridi4262996, 186 interactors
ComplexPortaliCPX-1083 Vitamin B12 outer membrane transporter complex
CPX-2843 Ferrichrome outer membrane transporter complex
CPX-3576 Ferric-citrate outer membrane transporter complex
CPX-3577 Ferric-catecholate outer membrane transporter complex
CPX-3578 Ferric-enterobactin outer membrane transporter complex
CPX-3579 Ferric-coprogen outer membrane transporter complex
CPX-3580 fiu outer membrane transporter complex
CPX-3585 Uncharacterized yncD-DHBS outer membrane transporter complex
DIPiDIP-48111N
IntActiP02929, 7 interactors
STRINGi511145.b1252

Chemistry databases

DrugBankiDB02767 3-Hydroxy-Myristic Acid
DB03017 Lauric Acid
DB04147 Lauryl Dimethylamine-N-Oxide
DB08231 MYRISTIC ACID

Protein family/group databases

TCDBi2.C.1.1.1 the tonb-exbb-exbd/tola-tolq-tolr outer membrane receptor energizers and stabilizers (tonb/tola) family

Proteomic databases

PaxDbiP02929
PRIDEiP02929

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74334; AAC74334; b1252
BAA14784; BAA14784; BAA14784
GeneIDi945843
KEGGiecj:JW5195
eco:b1252
PATRICifig|511145.12.peg.1302

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB1005
EcoGeneiEG11012 tonB

Phylogenomic databases

eggNOGiENOG410822N Bacteria
COG0810 LUCA
InParanoidiP02929
KOiK03832

Enzyme and pathway databases

BioCyciEcoCyc:EG11012-MONOMER
ECOL316407:JW5195-MONOMER
MetaCyc:EG11012-MONOMER

Miscellaneous databases

EvolutionaryTraceiP02929

Protein Ontology

More...
PROi
PR:P02929

Family and domain databases

DisProtiDP00043
InterProiView protein in InterPro
IPR003538 TonB
IPR006260 TonB/TolA_C
IPR037682 TonB_C
PfamiView protein in Pfam
PF03544 TonB_C, 1 hit
PRINTSiPR01374 TONBPROTEIN
TIGRFAMsiTIGR01352 tonB_Cterm, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTONB_ECOLI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P02929
Secondary accession number(s): P76831
, P94719, P94722, P94726, P94728, P94732, P94736, P94739, P97239
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 1, 1993
Last modified: July 31, 2019
This is version 171 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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