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Entry version 171 (03 Jul 2019)
Sequence version 1 (21 Jul 1986)
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Protein

Lactose permease

Gene

lacY

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D-galactopyranoside (TMG), but not sucrose or fructose (PubMed:1848449, PubMed:18177889, PubMed:22106930). The substrate specificity is directed toward the galactopyranosyl moiety of the substrate (PubMed:22106930).3 Publications

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=0.62 mM for lactose1 Publication
  2. KM=0.24 mM for melibiose1 Publication
  3. KM=0.24 mM for lactulose1 Publication
  4. KM=0.54 mM for TMG1 Publication
  1. Vmax=191 nmol/min/mg enzyme with lactose as substrate1 Publication
  2. Vmax=105 nmol/min/mg enzyme with melibiose as substrate1 Publication
  3. Vmax=49 nmol/min/mg enzyme with lactulose as substrate1 Publication
  4. Vmax=180 nmol/min/mg enzyme with TMG as substrate1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei126Substrate binding1 Publication1
Sitei144Substrate binding1 Publication1
Sitei269Substrate binding and proton translocation1 Publication1
Sitei302Proton translocation1 Publication1
Sitei322Proton translocation1 Publication1
Sitei325Proton translocation1 Publication1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processSugar transport, Symport, Transport

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
EcoCyc:LACY-MONOMER
ECOL316407:JW0334-MONOMER
MetaCyc:LACY-MONOMER

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.1.5.1 the major facilitator superfamily (mfs)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Lactose permease1 Publication
Alternative name(s):
Lactose-proton symport
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:lacY1 Publication
Ordered Locus Names:b0343, JW0334
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

Escherichia coli strain K12 genome database

More...
EcoGenei
EG10526 lacY

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 7Cytoplasmic1 Publication7
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei8 – 34Helical; Name=1Add BLAST27
Topological domaini35 – 41Periplasmic1 Publication7
Transmembranei42 – 70Helical; Name=2Add BLAST29
Topological domaini71 – 74Cytoplasmic1 Publication4
Transmembranei75 – 100Helical; Name=3Add BLAST26
Topological domaini101 – 104Periplasmic1 Publication4
Transmembranei105 – 129Helical; Name=4Add BLAST25
Topological domaini130 – 140Cytoplasmic1 PublicationAdd BLAST11
Transmembranei141 – 163Helical; Name=5Add BLAST23
Topological domaini164 – 166Periplasmic1 Publication3
Transmembranei167 – 186Helical; Name=6Add BLAST20
Topological domaini187 – 220Cytoplasmic1 PublicationAdd BLAST34
Transmembranei221 – 249Helical; Name=7Add BLAST29
Topological domaini250 – 253Periplasmic1 Publication4
Transmembranei254 – 278Helical; Name=8Add BLAST25
Topological domaini279 – 288Cytoplasmic1 Publication10
Transmembranei289 – 308Helical; Name=9Add BLAST20
Topological domaini309 – 311Periplasmic1 Publication3
Transmembranei312 – 334Helical; Name=10Add BLAST23
Topological domaini335 – 346Cytoplasmic1 PublicationAdd BLAST12
Transmembranei347 – 374Helical; Name=11Add BLAST28
Topological domaini375 – 377Periplasmic1 Publication3
Transmembranei378 – 398Helical; Name=12Add BLAST21
Topological domaini399 – 417Cytoplasmic2 PublicationsAdd BLAST19

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi65L → V: No change in transport activity. 1 Publication1
Mutagenesisi96G → A: No change in transport activity. 1 Publication1
Mutagenesisi122A → S: No change in transport activity. 1 Publication1
Mutagenesisi237D → N or G: Loss of activity. 1 Publication1
Mutagenesisi264V → A: No change in transport activity. 1 Publication1
Mutagenesisi279A → S: No change in transport activity. 1 Publication1
Mutagenesisi355C → Q: No change in transport activity. 1 Publication1
Mutagenesisi358K → T: Loss of activity. 1 Publication1
Mutagenesisi367V → A: Increases transport of melibiose and impairs transport of TMG. 1 Publication1

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB04396 Thiodigalactoside

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001961841 – 417Lactose permeaseAdd BLAST417

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-formylmethionine; partial1 Publication1

Keywords - PTMi

Formylation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P02920

PRoteomics IDEntifications database

More...
PRIDEi
P02920

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
4263185, 8 interactors

Database of interacting proteins

More...
DIPi
DIP-10080N

STRING: functional protein association networks

More...
STRINGi
511145.b0343

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1417
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P02920

Database of comparative protein structure models

More...
ModBasei
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P02920

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105U0F Bacteria
ENOG410XQTD LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000114363

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P02920

KEGG Orthology (KO)

More...
KOi
K02532

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P02920

Family and domain databases

Conserved Domains Database

More...
CDDi
cd06174 MFS, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000576 LacY/RafB_perm_fam
IPR018457 LacY/RafB_perm_fam_CS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01306 LacY_symp, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00174 LACYSMPORT

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103473 SSF103473, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00882 2A0105, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00896 LACY_1, 1 hit
PS00897 LACY_2, 1 hit
PS50850 MFS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P02920-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYYLKNTNFW MFGLFFFFYF FIMGAYFPFF PIWLHDINHI SKSDTGIIFA
60 70 80 90 100
AISLFSLLFQ PLFGLLSDKL GLRKYLLWII TGMLVMFAPF FIFIFGPLLQ
110 120 130 140 150
YNILVGSIVG GIYLGFCFNA GAPAVEAFIE KVSRRSNFEF GRARMFGCVG
160 170 180 190 200
WALCASIVGI MFTINNQFVF WLGSGCALIL AVLLFFAKTD APSSATVANA
210 220 230 240 250
VGANHSAFSL KLALELFRQP KLWFLSLYVI GVSCTYDVFD QQFANFFTSF
260 270 280 290 300
FATGEQGTRV FGYVTTMGEL LNASIMFFAP LIINRIGGKN ALLLAGTIMS
310 320 330 340 350
VRIIGSSFAT SALEVVILKT LHMFEVPFLL VGCFKYITSQ FEVRFSATIY
360 370 380 390 400
LVCFCFFKQL AMIFMSVLAG NMYESIGFQG AYLVLGLVAL GFTLISVFTL
410
SGPGPLSLLR RQVNEVA
Length:417
Mass (Da):46,503
Last modified:July 21, 1986 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i24A8062F628CDA32
GO

<p>This subsection of the ‘Sequence’ section reports information derived from mass spectrometry experiments done on the entire protein or on biologically active derived peptide(s).<p><a href='/help/mass_spectrometry' target='_top'>More...</a></p>Mass spectrometryi

Molecular mass is 47357 Da from positions 1 - 417. Determined by ESI. 1 Publication

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
J01636 Genomic DNA Translation: AAA24054.1
V00295 Genomic DNA Translation: CAA23571.1
X56095 Genomic DNA Translation: CAA39575.1
U73857 Genomic DNA Translation: AAB18067.1
U00096 Genomic DNA Translation: AAC73446.1
AP009048 Genomic DNA Translation: BAE76125.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A03418 GREC

NCBI Reference Sequences

More...
RefSeqi
NP_414877.1, NC_000913.3
WP_000291549.1, NZ_LN832404.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC73446; AAC73446; b0343
BAE76125; BAE76125; BAE76125

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
949083

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ecj:JW0334
eco:b0343

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1411691.4.peg.1934

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J01636 Genomic DNA Translation: AAA24054.1
V00295 Genomic DNA Translation: CAA23571.1
X56095 Genomic DNA Translation: CAA39575.1
U73857 Genomic DNA Translation: AAB18067.1
U00096 Genomic DNA Translation: AAC73446.1
AP009048 Genomic DNA Translation: BAE76125.1
PIRiA03418 GREC
RefSeqiNP_414877.1, NC_000913.3
WP_000291549.1, NZ_LN832404.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1M2Umodel-A1-417[»]
1PV6X-ray3.50A/B1-417[»]
1PV7X-ray3.60A/B1-417[»]
2CFPX-ray3.30A1-417[»]
2CFQX-ray2.95A1-417[»]
2V8NX-ray3.60A/B1-417[»]
2Y5YX-ray3.38A/B1-417[»]
4ZYRX-ray3.31A/B1-417[»]
5GXBX-ray3.30A1-417[»]
6C9WX-ray3.00A1-417[»]
SMRiP02920
ModBaseiSearch...

Protein-protein interaction databases

BioGridi4263185, 8 interactors
DIPiDIP-10080N
STRINGi511145.b0343

Chemistry databases

DrugBankiDB04396 Thiodigalactoside

Protein family/group databases

TCDBi2.A.1.5.1 the major facilitator superfamily (mfs)

Proteomic databases

PaxDbiP02920
PRIDEiP02920

Protocols and materials databases

ABCD curated depository of sequenced antibodies

More...
ABCDi
P02920
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73446; AAC73446; b0343
BAE76125; BAE76125; BAE76125
GeneIDi949083
KEGGiecj:JW0334
eco:b0343
PATRICifig|1411691.4.peg.1934

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB0521
EcoGeneiEG10526 lacY

Phylogenomic databases

eggNOGiENOG4105U0F Bacteria
ENOG410XQTD LUCA
HOGENOMiHOG000114363
InParanoidiP02920
KOiK02532
PhylomeDBiP02920

Enzyme and pathway databases

BioCyciEcoCyc:LACY-MONOMER
ECOL316407:JW0334-MONOMER
MetaCyc:LACY-MONOMER

Miscellaneous databases

EvolutionaryTraceiP02920

Protein Ontology

More...
PROi
PR:P02920

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR000576 LacY/RafB_perm_fam
IPR018457 LacY/RafB_perm_fam_CS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
PfamiView protein in Pfam
PF01306 LacY_symp, 1 hit
PRINTSiPR00174 LACYSMPORT
SUPFAMiSSF103473 SSF103473, 1 hit
TIGRFAMsiTIGR00882 2A0105, 1 hit
PROSITEiView protein in PROSITE
PS00896 LACY_1, 1 hit
PS00897 LACY_2, 1 hit
PS50850 MFS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLACY_ECOLI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P02920
Secondary accession number(s): Q2MC81
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: July 3, 2019
This is version 171 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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