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Protein

Thaumatin I

Gene
N/A
Organism
Thaumatococcus daniellii (Katemfe) (Phrynium daniellii)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Taste-modifying protein; intensely sweet-tasting. It is 100000 times sweeter than sucrose on a molar basis.1 Publication

Keywordsi

Molecular functionTaste-modifying protein

Names & Taxonomyi

Protein namesi
Recommended name:
Thaumatin I1 Publication
Alternative name(s):
Thaumatin-1Curated
OrganismiThaumatococcus daniellii (Katemfe) (Phrynium daniellii)
Taxonomic identifieri4621 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaZingiberalesMarantaceaeThaumatococcus

Subcellular locationi

Keywords - Cellular componenti

Cytoplasmic vesicle

Pathology & Biotechi

Protein family/group databases

Allergomei9233 Tha da TLP

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 221 PublicationAdd BLAST22
ChainiPRO_000009622123 – 229Thaumatin I1 PublicationAdd BLAST207
PropeptideiPRO_0000443721230 – 235Removed in mature form1 Publication6

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi31 ↔ 226PROSITE-ProRule annotationCombined sources3 Publications
Disulfide bondi78 ↔ 88PROSITE-ProRule annotationCombined sources3 Publications
Disulfide bondi93 ↔ 99PROSITE-ProRule annotationCombined sources3 Publications
Disulfide bondi143 ↔ 215PROSITE-ProRule annotationCombined sources3 Publications
Disulfide bondi148 ↔ 199PROSITE-ProRule annotationCombined sources3 Publications
Disulfide bondi156 ↔ 167PROSITE-ProRule annotationCombined sources3 Publications
Disulfide bondi171 ↔ 180PROSITE-ProRule annotationCombined sources3 Publications
Disulfide bondi181 ↔ 186PROSITE-ProRule annotationCombined sources3 Publications

Keywords - PTMi

Disulfide bond

Proteomic databases

PRIDEiP02883

Structurei

Secondary structure

1235
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP02883
SMRiP02883
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP02883

Family & Domainsi

Sequence similaritiesi

Belongs to the thaumatin family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.60.110.10, 1 hit
InterProiView protein in InterPro
IPR037176 Osmotin/thaumatin-like_sf
IPR001938 Thaumatin
IPR017949 Thaumatin_CS
PANTHERiPTHR31048 PTHR31048, 1 hit
PfamiView protein in Pfam
PF00314 Thaumatin, 1 hit
PIRSFiPIRSF002703 Thaumatin, 1 hit
PRINTSiPR00347 THAUMATIN
SMARTiView protein in SMART
SM00205 THN, 1 hit
SUPFAMiSSF49870 SSF49870, 1 hit
PROSITEiView protein in PROSITE
PS00316 THAUMATIN_1, 1 hit
PS51367 THAUMATIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P02883-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAATTCFFFL FPFLLLLTLS RAATFEIVNR CSYTVWAAAS KGDAALDAGG
60 70 80 90 100
RQLNSGESWT INVEPGTNGG KIWARTDCYF DDSGSGICKT GDCGGLLRCK
110 120 130 140 150
RFGRPPTTLA EFSLNQYGKD YIDISNIKGF NVPMDFSPTT RGCRGVRCAA
160 170 180 190 200
DIVGQCPAKL KAPGGGCNDA CTVFQTSEYC CTTGKCGPTE YSRFFKRLCP
210 220 230
DAFSYVLDKP TTVTCPGSSN YRVTFCPTAL ELEDE
Length:235
Mass (Da):25,440
Last modified:March 28, 2018 - v2
Checksum:i9E1A62D6B1EE8FEF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB265690 mRNA Translation: BAF44567.1
AF355098 mRNA Translation: AAL83964.1
PIRiA03377 QTTC1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB265690 mRNA Translation: BAF44567.1
AF355098 mRNA Translation: AAL83964.1
PIRiA03377 QTTC1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1LR2X-ray1.80A23-229[»]
1LR3X-ray1.80A23-229[»]
1LXZX-ray1.25A23-229[»]
1LY0X-ray1.36A23-229[»]
1PP3X-ray1.60A/B23-229[»]
1RQWX-ray1.05A23-229[»]
1THIX-ray3.20A23-229[»]
1THUX-ray2.60A23-229[»]
1THVX-ray1.75A23-229[»]
1THWX-ray1.75A23-229[»]
2A7IX-ray1.75X23-229[»]
2BLRX-ray1.40A23-228[»]
2BLUX-ray1.40A23-228[»]
2D8OX-ray2.38A23-229[»]
2D8PX-ray2.30A23-229[»]
2G4YX-ray1.98A23-229[»]
2OQNX-ray1.90A23-229[»]
2PE7X-ray1.46A23-229[»]
2VHKX-ray0.94A23-228[»]
2VHRX-ray0.95A23-229[»]
2VI1X-ray1.04A23-229[»]
2VI2X-ray1.08A23-229[»]
2VI3X-ray0.98A23-229[»]
2VI4X-ray1.10A23-229[»]
2VU6X-ray0.95A23-229[»]
2VU7X-ray1.08A23-229[»]
2WBZX-ray1.60A23-228[»]
3AL7X-ray1.10A23-229[»]
3ALDX-ray1.10A23-229[»]
3DZNX-ray1.51A23-229[»]
3DZPX-ray1.51A23-229[»]
3DZRX-ray1.51A23-229[»]
3E0AX-ray1.51A23-229[»]
3E3SX-ray1.73A23-229[»]
3N02X-ray1.50A23-228[»]
3N03X-ray1.50A23-228[»]
3QY5X-ray1.25A23-229[»]
3V7VX-ray2.30A23-229[»]
3V82X-ray2.30A23-229[»]
3V84X-ray2.30A23-229[»]
3V87X-ray2.30A23-229[»]
3V88X-ray2.30A23-229[»]
3V8AX-ray2.30A23-229[»]
3VCEX-ray2.30A23-229[»]
3VCGX-ray2.30A23-229[»]
3VCHX-ray2.30A23-229[»]
3VCIX-ray2.30A23-229[»]
3VCJX-ray2.30A23-229[»]
3VCKX-ray2.30A23-229[»]
3VHFX-ray1.39A23-229[»]
3VHGX-ray1.00A23-229[»]
3VJQX-ray1.00A23-229[»]
3WXSX-ray2.00A23-229[»]
3X3OX-ray1.48A23-229[»]
3X3PX-ray1.48A23-229[»]
3X3QX-ray1.50A23-229[»]
3X3RX-ray1.52A23-229[»]
3X3SX-ray1.46A23-229[»]
3X3TX-ray1.50A23-229[»]
3ZEJX-ray1.55A23-229[»]
4AXRX-ray1.38A23-229[»]
4AXUX-ray1.38A23-228[»]
4BALX-ray1.30A23-229[»]
4BARX-ray1.20A23-229[»]
4C3CX-ray1.80A23-229[»]
4DC5X-ray1.48A23-229[»]
4DC6X-ray1.48A23-229[»]
4DIYX-ray1.98A23-229[»]
4DIZX-ray1.98A23-229[»]
4DJ0X-ray1.98A23-229[»]
4DJ1X-ray1.98A23-229[»]
4EK0X-ray1.52A23-229[»]
4EKAX-ray1.55A23-229[»]
4EKBX-ray1.52A23-229[»]
4EKHX-ray1.75A23-229[»]
4EKOX-ray1.52A23-229[»]
4EKTX-ray1.75A23-229[»]
4EL2X-ray1.52A23-229[»]
4EL3X-ray1.95A23-229[»]
4EL7X-ray1.52A23-229[»]
4ELAX-ray2.00A23-229[»]
4TVTX-ray1.20A23-229[»]
4XVBX-ray1.52A23-229[»]
4ZG3X-ray1.20A23-229[»]
4ZXRX-ray1.92A23-229[»]
5A47X-ray1.20A23-229[»]
5AMZX-ray1.40A23-228[»]
5AVGX-ray0.95A23-228[»]
5FGTX-ray2.10A23-229[»]
5FGXX-ray2.13A23-229[»]
5GQPX-ray1.30A23-229[»]
5JVXX-ray1.70A23-229[»]
5K7Qelectron microscopy2.50A23-229[»]
5KVWX-ray1.59A23-229[»]
5KVXX-ray1.59A23-229[»]
5KVZX-ray1.59A23-229[»]
5KW0X-ray1.59A23-229[»]
5KW3X-ray1.55A23-229[»]
5KW4X-ray1.55A23-229[»]
5KW5X-ray1.55A23-229[»]
5KW7X-ray1.55A23-229[»]
5KW8X-ray1.55A23-229[»]
5L4RX-ray1.45A23-229[»]
5LH0X-ray1.88A23-229[»]
5LH1X-ray1.90A23-229[»]
5LH3X-ray1.64A23-229[»]
5LH5X-ray1.69A23-229[»]
5LH6X-ray2.16A23-229[»]
5LH7X-ray2.28A23-229[»]
5LMHX-ray1.96A23-229[»]
5LN0X-ray1.95A23-229[»]
5MJGX-ray2.10A23-229[»]
5SW0X-ray1.27A23-229[»]
5SW1X-ray1.10A23-229[»]
5SW2X-ray1.20A23-229[»]
5T3GX-ray1.55A23-229[»]
5TCLX-ray3.20A23-229[»]
5WR8X-ray1.55A23-229[»]
5X9LX-ray0.90A1-207[»]
5X9MX-ray0.93A1-207[»]
5YYPX-ray1.01A23-229[»]
5YYQX-ray1.07A23-229[»]
5YYRX-ray1.07A23-229[»]
6C5YX-ray2.50A23-229[»]
6C6WX-ray2.23A1-207[»]
6COAX-ray1.20A23-229[»]
6E0DX-ray2.24A1-235[»]
6FJ6X-ray1.08A1-207[»]
6FJ8X-ray1.50A1-207[»]
6FJ9X-ray1.50A1-207[»]
6G89X-ray2.36C23-228[»]
ProteinModelPortaliP02883
SMRiP02883
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei9233 Tha da TLP

Proteomic databases

PRIDEiP02883

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP02883

Family and domain databases

Gene3Di2.60.110.10, 1 hit
InterProiView protein in InterPro
IPR037176 Osmotin/thaumatin-like_sf
IPR001938 Thaumatin
IPR017949 Thaumatin_CS
PANTHERiPTHR31048 PTHR31048, 1 hit
PfamiView protein in Pfam
PF00314 Thaumatin, 1 hit
PIRSFiPIRSF002703 Thaumatin, 1 hit
PRINTSiPR00347 THAUMATIN
SMARTiView protein in SMART
SM00205 THN, 1 hit
SUPFAMiSSF49870 SSF49870, 1 hit
PROSITEiView protein in PROSITE
PS00316 THAUMATIN_1, 1 hit
PS51367 THAUMATIN_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTHM1_THADA
AccessioniPrimary (citable) accession number: P02883
Secondary accession number(s): A1IIJ1, Q8RVT0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: March 28, 2018
Last modified: November 7, 2018
This is version 119 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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Main funding by: National Institutes of Health

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