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Protein

Secapin

Gene
N/A
Organism
Apis mellifera (Honeybee)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Nontoxic component of honeybee venom.

Names & Taxonomyi

Protein namesi
Recommended name:
Secapin
OrganismiApis mellifera (Honeybee)
Taxonomic identifieri7460 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaHymenopteraApocritaAculeataApoideaApidaeApis
Proteomesi
  • UP000005203 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 32Add BLAST32
PropeptideiPRO_000002229033 – 521 PublicationAdd BLAST20
PeptideiPRO_000002229153 – 77SecapinAdd BLAST25

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi61 ↔ 72

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom gland.

Family & Domainsi

Sequence similaritiesi

Belongs to the secapin family.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR020128 Secapin
PfamiView protein in Pfam
PF17521 Secapin, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD058010 Secapin, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P02852-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKNYSKNATH LITVLLFSFV VILLIIPSKC EAVSNDMQPL EARSADLVPE
60 70
PRYIIDVPPR CPPGSKFIKN RCRVIVP
Length:77
Mass (Da):8,664
Last modified:July 11, 2006 - v2
Checksum:i7FD5D7E72DA6B3EA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti37 – 39MQP → RQS in AAA27733 (PubMed:6548708).Curated3
Sequence conflicti75 – 77IVP → PV AA sequence (PubMed:631126).Curated3

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M12598 mRNA Translation: AAA27733.1
AY082691 mRNA Translation: AAL92482.1
PIRiA91139 WSHB
RefSeqiNP_001011618.1, NM_001011618.1
UniGeneiAme.3

Genome annotation databases

GeneIDi406145
KEGGiame:406145

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M12598 mRNA Translation: AAA27733.1
AY082691 mRNA Translation: AAL92482.1
PIRiA91139 WSHB
RefSeqiNP_001011618.1, NM_001011618.1
UniGeneiAme.3

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi406145
KEGGiame:406145

Family and domain databases

InterProiView protein in InterPro
IPR020128 Secapin
PfamiView protein in Pfam
PF17521 Secapin, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD058010 Secapin, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSECP_APIME
AccessioniPrimary (citable) accession number: P02852
Secondary accession number(s): Q8ISJ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 11, 2006
Last modified: July 5, 2017
This is version 66 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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