Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 163 (12 Aug 2020)
Sequence version 2 (01 Jul 1989)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Statherin

Gene

STATH

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Salivary protein that stabilizes saliva supersaturated with calcium salts by inhibiting the precipitation of calcium phosphate salts. It also modulates hydroxyapatite crystal formation on the tooth surface.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processBiomineralization

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
P02808

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.C.79.1.2, the channel-forming histatin antimicrobial peptide (histatin) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Statherin
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:STATH
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000126549.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:11369, STATH

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
184470, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P02808

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
6779

Open Targets

More...
OpenTargetsi
ENSG00000126549

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA36187

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P02808, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
STATH

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 191 PublicationAdd BLAST19
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000002242220 – 62StatherinAdd BLAST43

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei21Phosphoserine1 Publication1
Modified residuei22Phosphoserine1 Publication1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki25 ↔ 58Isoglutamyl lysine isopeptide (Lys-Gln); in form cyclo-statherin Q-39
Cross-linki25 ↔ 56Isoglutamyl lysine isopeptide (Lys-Gln); in form cyclo-statherin Q-37

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Substrate for transglutaminase-2. More than 95% of the cyclized peptide is cyclo-statherin Q-37, and less than 5% is cyclo-statherin Q-39. Cyclized forms account for about 1% of total statherin in saliva.1 Publication
Sulfated on tyrosine residues.1 Publication

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Sulfation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P02808

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P02808

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P02808

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P02808

PeptideAtlas

More...
PeptideAtlasi
P02808

PRoteomics IDEntifications database

More...
PRIDEi
P02808

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
1407
51602 [P02808-1]

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P02808-1 [P02808-1]
P02808-2 [P02808-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P02808

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P02808

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Secreted by parotid and submandibular glands.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000126549, Expressed in saliva-secreting gland and 116 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P02808, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000126549, Tissue enriched (salivary)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni20 – 25Hydroxyapatite-binding; inhibits crystal growth6
Regioni38 – 62Hydrophobic; inhibits precipitation of calcium phosphate saltsAdd BLAST25

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the histatin/statherin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502TD50, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164572

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_208169_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P02808

KEGG Orthology (KO)

More...
KOi
K13914

Identification of Orthologs from Complete Genome Data

More...
OMAi
SSEEYAY

Database of Orthologous Groups

More...
OrthoDBi
1640595at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P02808

TreeFam database of animal gene trees

More...
TreeFami
TF341588

Family and domain databases

Database of protein disorder

More...
DisProti
DP02207

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR030773, Histatin/statherin
IPR005575, Statherin

The PANTHER Classification System

More...
PANTHERi
PTHR15057, PTHR15057, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03875, Statherin, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002565, Statherin, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Note: Both isoforms can occur with the Phe-62 deletion.
Isoform 1 (identifier: P02808-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKFLVFAFIL ALMVSMIGAD SSEEKFLRRI GRFGYGYGPY QPVPEQPLYP
60
QPYQPQYQQY TF
Length:62
Mass (Da):7,304
Last modified:July 1, 1989 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCFE32EC235CA3A22
GO
Isoform 2 (identifier: P02808-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     25-34: Missing.

Show »
Length:52
Mass (Da):6,073
Checksum:iC94F2FE112DAA733
GO

<p>This subsection of the 'Sequence' section reports information derived from mass spectrometry experiments done on the entire protein or on biologically active derived peptide(s).<p><a href='/help/mass_spectrometry' target='_top'>More...</a></p>Mass spectrometryi

Molecular mass is 5380.0±0.3 Da. Determined by ESI. With phosphorylated Ser-21 and Ser-22.1 Publication
Molecular mass is 5363.0±0.3 Da. Determined by ESI. With phosphorylated Ser-21 and Ser-22 and transglutamine cross-link.1 Publication

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_06906562Missing 1 Publication1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04574425 – 34Missing in isoform 2. Curated10

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M18078 mRNA Translation: AAA60594.1
M18371 mRNA Translation: AAA60600.1
M32639 Genomic DNA Translation: AAA60593.1
AK311812 mRNA Translation: BAG34755.1
AC063956 Genomic DNA No translation available.
CH471057 Genomic DNA Translation: EAX05604.1
CH471057 Genomic DNA Translation: EAX05605.1
BC067219 mRNA Translation: AAH67219.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS33998.1 [P02808-2]
CCDS3533.1 [P02808-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
JH0153, SBHUP

NCBI Reference Sequences

More...
RefSeqi
NP_001009181.1, NM_001009181.1 [P02808-2]
NP_003145.1, NM_003154.2 [P02808-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000246895; ENSP00000246895; ENSG00000126549 [P02808-1]
ENST00000381060; ENSP00000370448; ENSG00000126549 [P02808-2]
ENST00000615994; ENSP00000484341; ENSG00000126549 [P02808-1]
ENST00000634727; ENSP00000489107; ENSG00000282891 [P02808-2]
ENST00000635437; ENSP00000489569; ENSG00000282891 [P02808-1]
ENST00000635686; ENSP00000489243; ENSG00000282891 [P02808-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
6779

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:6779

UCSC genome browser

More...
UCSCi
uc003heu.2, human [P02808-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M18078 mRNA Translation: AAA60594.1
M18371 mRNA Translation: AAA60600.1
M32639 Genomic DNA Translation: AAA60593.1
AK311812 mRNA Translation: BAG34755.1
AC063956 Genomic DNA No translation available.
CH471057 Genomic DNA Translation: EAX05604.1
CH471057 Genomic DNA Translation: EAX05605.1
BC067219 mRNA Translation: AAH67219.1
CCDSiCCDS33998.1 [P02808-2]
CCDS3533.1 [P02808-1]
PIRiJH0153, SBHUP
RefSeqiNP_001009181.1, NM_001009181.1 [P02808-2]
NP_003145.1, NM_003154.2 [P02808-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi112656, 5 interactors
IntActiP02808, 25 interactors
STRINGi9606.ENSP00000246895

Protein family/group databases

TCDBi1.C.79.1.2, the channel-forming histatin antimicrobial peptide (histatin) family

PTM databases

iPTMnetiP02808
PhosphoSitePlusiP02808

Polymorphism and mutation databases

BioMutaiSTATH

Proteomic databases

EPDiP02808
MassIVEiP02808
MaxQBiP02808
PaxDbiP02808
PeptideAtlasiP02808
PRIDEiP02808
ProteomicsDBi1407
51602 [P02808-1]
TopDownProteomicsiP02808-1 [P02808-1]
P02808-2 [P02808-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
44306, 59 antibodies

Genome annotation databases

EnsembliENST00000246895; ENSP00000246895; ENSG00000126549 [P02808-1]
ENST00000381060; ENSP00000370448; ENSG00000126549 [P02808-2]
ENST00000615994; ENSP00000484341; ENSG00000126549 [P02808-1]
ENST00000634727; ENSP00000489107; ENSG00000282891 [P02808-2]
ENST00000635437; ENSP00000489569; ENSG00000282891 [P02808-1]
ENST00000635686; ENSP00000489243; ENSG00000282891 [P02808-1]
GeneIDi6779
KEGGihsa:6779
UCSCiuc003heu.2, human [P02808-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6779
DisGeNETi6779
EuPathDBiHostDB:ENSG00000126549.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
STATH
HGNCiHGNC:11369, STATH
HPAiENSG00000126549, Tissue enriched (salivary)
MIMi184470, gene
neXtProtiNX_P02808
OpenTargetsiENSG00000126549
PharmGKBiPA36187

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502TD50, Eukaryota
GeneTreeiENSGT00940000164572
HOGENOMiCLU_208169_0_0_1
InParanoidiP02808
KOiK13914
OMAiSSEEYAY
OrthoDBi1640595at2759
PhylomeDBiP02808
TreeFamiTF341588

Enzyme and pathway databases

PathwayCommonsiP02808

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
6779, 5 hits in 864 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
STATH, human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
STATH

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
6779
PharosiP02808, Tbio

Protein Ontology

More...
PROi
PR:P02808
RNActiP02808, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000126549, Expressed in saliva-secreting gland and 116 other tissues
GenevisibleiP02808, HS

Family and domain databases

DisProtiDP02207
InterProiView protein in InterPro
IPR030773, Histatin/statherin
IPR005575, Statherin
PANTHERiPTHR15057, PTHR15057, 1 hit
PfamiView protein in Pfam
PF03875, Statherin, 1 hit
PIRSFiPIRSF002565, Statherin, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSTAT_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P02808
Secondary accession number(s): A6NKE9, B2R4F8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 1, 1989
Last modified: August 12, 2020
This is version 163 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again