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Protein

Metallothionein

Gene

cmt

Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

The seven cysteines bind six copper (cuprous) ions.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi4Copper1
Metal bindingi6Copper1
Metal bindingi12Copper1
Metal bindingi14Copper1
Metal bindingi18Copper1
Metal bindingi20Copper1
Metal bindingi23Copper1

GO - Molecular functioni

Keywordsi

LigandCopper, Metal-binding, Metal-thiolate cluster

Names & Taxonomyi

Protein namesi
Recommended name:
Metallothionein
Short name:
MT
Gene namesi
Name:cmt
Synonyms:ccg-12
ORF Names:NCU05561
OrganismiNeurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Taxonomic identifieri367110 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora
Proteomesi
  • UP000001805 Componenti: Chromosome 5, Linkage Group VI

Organism-specific databases

EuPathDBiFungiDB:NCU05561

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
PeptideiPRO_00001973642 – 26MetallothioneinAdd BLAST25

Expressioni

Inductioni

By copper.

Structurei

Secondary structure

126
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SMRiP02807
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP02807

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiView protein in InterPro
IPR017854 Metalthion_dom_sf
SUPFAMiSSF57868 SSF57868, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P02807-1 [UniParc]FASTAAdd to basket
« Hide
        10         20 
MGDCGCSGAS SCNCGSGCSC SNCGSK
Length:26
Mass (Da):2,366
Last modified:January 23, 2007 - v2
Checksum:i252562AE5FD422FC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti22N → T in AAA33594 (PubMed:2148862).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X03009 Genomic DNA Translation: CAA26793.1
M59836 Genomic DNA Translation: AAA33594.1
M27709 Genomic DNA Translation: AAA33595.1
CM002241 Genomic DNA Translation: ESA42185.1
PIRiA24641 SMNC
RefSeqiXP_011394960.1, XM_011396658.1

Genome annotation databases

EnsemblFungiiESA42185; ESA42185; NCU05561
GeneIDi23568444
KEGGincr:NCU05561

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X03009 Genomic DNA Translation: CAA26793.1
M59836 Genomic DNA Translation: AAA33594.1
M27709 Genomic DNA Translation: AAA33595.1
CM002241 Genomic DNA Translation: ESA42185.1
PIRiA24641 SMNC
RefSeqiXP_011394960.1, XM_011396658.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1T2YNMR-A2-26[»]
SMRiP02807
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiESA42185; ESA42185; NCU05561
GeneIDi23568444
KEGGincr:NCU05561

Organism-specific databases

EuPathDBiFungiDB:NCU05561

Miscellaneous databases

EvolutionaryTraceiP02807

Family and domain databases

InterProiView protein in InterPro
IPR017854 Metalthion_dom_sf
SUPFAMiSSF57868 SSF57868, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMT_NEUCR
AccessioniPrimary (citable) accession number: P02807
Secondary accession number(s): Q7S702, V5ILF3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 100 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Metallothioneins
    Classification of metallothioneins and list of entries
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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Main funding by: National Institutes of Health

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