Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 101 (13 Nov 2019)
Sequence version 1 (21 Jul 1986)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Sodium channel protein

Gene
N/A
Organism
Electrophorus electricus (Electric eel) (Gymnotus electricus)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.1 Publication

Miscellaneous

Available data suggest that activation and inactivation gates are located near the cytoplasmic surface of the membrane. It is hypothesized that residues 802-806, 847-857, 894-910, and 942-955 might, in conjunction with the positively charged residues of S4, act as a voltage sensor involved with the activation gate.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIon channel, Sodium channel, Voltage-gated channel
Biological processIon transport, Sodium transport, Transport
LigandSodium

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.A.1.10.19 the voltage-gated ion channel (vic) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sodium channel protein
Alternative name(s):
Na(+) channel
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiElectrophorus electricus (Electric eel) (Gymnotus electricus)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8005 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiGymnotiformesGymnotoideiGymnotidaeElectrophorus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000314983 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 117CytoplasmicCuratedAdd BLAST117
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei118 – 138Helical; Name=S1 of repeat IAdd BLAST21
Topological domaini139 – 149ExtracellularCuratedAdd BLAST11
Transmembranei150 – 171Helical; Name=S2 of repeat IAdd BLAST22
Topological domaini172 – 176CytoplasmicCurated5
Transmembranei177 – 197Helical; Name=S3 of repeat IAdd BLAST21
Topological domaini198 – 203ExtracellularCurated6
Transmembranei204 – 224Helical; Voltage-sensor; Name=S4 of repeat IAdd BLAST21
Topological domaini225 – 243CytoplasmicCuratedAdd BLAST19
Transmembranei244 – 264Helical; Name=S5 of repeat IAdd BLAST21
Topological domaini265 – 346ExtracellularCuratedAdd BLAST82
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a region that is buried within a membrane, but does not cross it.<p><a href='/help/intramem' target='_top'>More...</a></p>Intramembranei347 – 371Pore-formingBy similarityAdd BLAST25
Topological domaini372 – 378ExtracellularCurated7
Transmembranei379 – 402Helical; Name=S6 of repeat IAdd BLAST24
Topological domaini403 – 557CytoplasmicCuratedAdd BLAST155
Transmembranei558 – 578Helical; Name=S1 of repeat IIAdd BLAST21
Topological domaini579 – 599ExtracellularCuratedAdd BLAST21
Transmembranei600 – 620Helical; Name=S2 of repeat IIAdd BLAST21
Topological domaini621 – 625CytoplasmicCurated5
Transmembranei626 – 643Helical; Name=S3 of repeat IIAdd BLAST18
Topological domaini644 – 650ExtracellularCurated7
Transmembranei651 – 671Helical; Voltage-sensor; Name=S4 of repeat IIAdd BLAST21
Topological domaini672 – 690CytoplasmicCuratedAdd BLAST19
Transmembranei691 – 711Helical; Name=S5 of repeat IIAdd BLAST21
Topological domaini712 – 734ExtracellularCuratedAdd BLAST23
Intramembranei735 – 755Pore-formingBy similarityAdd BLAST21
Topological domaini756 – 766ExtracellularCuratedAdd BLAST11
Transmembranei767 – 790Helical; Name=S6 of repeat IIAdd BLAST24
Topological domaini791 – 1004CytoplasmicCuratedAdd BLAST214
Transmembranei1005 – 1025Helical; Name=S1 of repeat IIIAdd BLAST21
Topological domaini1026 – 1037ExtracellularCuratedAdd BLAST12
Transmembranei1038 – 1058Helical; Name=S2 of repeat IIIAdd BLAST21
Topological domaini1059 – 1065CytoplasmicCurated7
Transmembranei1066 – 1086Helical; Name=S3 of repeat IIIAdd BLAST21
Topological domaini1087 – 1091ExtracellularCurated5
Transmembranei1092 – 1112Helical; Voltage-sensor; Name=S4 of repeat IIIAdd BLAST21
Topological domaini1113 – 1131CytoplasmicCuratedAdd BLAST19
Transmembranei1132 – 1152Helical; Name=S5 of repeat IIIAdd BLAST21
Topological domaini1153 – 1199ExtracellularCuratedAdd BLAST47
Intramembranei1200 – 1221Pore-formingBy similarityAdd BLAST22
Topological domaini1222 – 1243ExtracellularCuratedAdd BLAST22
Transmembranei1244 – 1264Helical; Name=S6 of repeat IIIAdd BLAST21
Topological domaini1265 – 1320CytoplasmicCuratedAdd BLAST56
Transmembranei1321 – 1341Helical; Name=S1 of repeat IVAdd BLAST21
Topological domaini1342 – 1352ExtracellularCuratedAdd BLAST11
Transmembranei1353 – 1376Helical; Name=S2 of repeat IVAdd BLAST24
Topological domaini1377 – 1380CytoplasmicCurated4
Transmembranei1381 – 1398Helical; Name=S3 of repeat IVAdd BLAST18
Topological domaini1399 – 1416ExtracellularCuratedAdd BLAST18
Transmembranei1417 – 1437Helical; Voltage-sensor; Name=S4 of repeat IVAdd BLAST21
Topological domaini1438 – 1453CytoplasmicCuratedAdd BLAST16
Transmembranei1454 – 1474Helical; Name=S5 of repeat IVAdd BLAST21
Topological domaini1475 – 1490ExtracellularCuratedAdd BLAST16
Intramembranei1491 – 1513Pore-formingBy similarityAdd BLAST23
Topological domaini1514 – 1543ExtracellularCuratedAdd BLAST30
Transmembranei1544 – 1567Helical; Name=S6 of repeat IVAdd BLAST24
Topological domaini1568 – 1820CytoplasmicCuratedAdd BLAST253

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000485131 – 1820Sodium channel proteinAdd BLAST1820

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi271 ↔ 324By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi278N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi288N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi317N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi591N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi757 ↔ 766By similarity
Glycosylationi1160N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1174N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
P02719

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P02719

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P02719

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati108 – 410ICuratedAdd BLAST303
Repeati548 – 811IICuratedAdd BLAST264
Repeati988 – 1295IIICuratedAdd BLAST308
Repeati1304 – 1602IVCuratedAdd BLAST299

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni285 – 342Non-homologous region of repeat IAdd BLAST58
Regioni1172 – 1194Non-homologous region of repeat IIIAdd BLAST23
Regioni1490 – 1505Non-homologous region of repeat IVAdd BLAST16

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The sequence contains 4 internal repeats, each with 5 hydrophobic segments (S1, S2, S3, S5, S6) and one positively charged segment (S4). Segments S4 are probably the voltage-sensors and are characterized by a series of positively charged amino acids at every third position.1 Publication

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.120.350, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005821 Ion_trans_dom
IPR001696 Na_channel_asu
IPR010526 Na_trans_assoc
IPR027359 Volt_channel_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00520 Ion_trans, 4 hits
PF06512 Na_trans_assoc, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00170 NACHANNEL

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P02719-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARKFSSARP EMFRRFTPDS LEEIEAFTEL KKSCTLEKKE PESTPRIDLE
60 70 80 90 100
AGKPLPMIYG DPPEDLLNIP LEDLDPFYKT QKTFIVISKG NIINRFNAER
110 120 130 140 150
ALYIFSPFNP IRRGAIRVFV NSAFNFFIMF TIFSNCIFMT ISNPPAWSKI
160 170 180 190 200
VEYTFTGIYT FEVIVKVLSR GFCIGHFTFL RDPWNWLDFS VVTMTYITEF
210 220 230 240 250
IDLRNVSALR TFRVLRALKT ITIFPGLKTI VRALIESMKQ MGDVVILTVF
260 270 280 290 300
SLAVFTLAGM QLFMGNLRHK CIRWPISNVT LDYESAYNTT FDFTAYIENE
310 320 330 340 350
ENQYFLDGAL DALLCGNNSD AGKCPEGYTC MKAGRNPNYG YTNYDNFAWT
360 370 380 390 400
FLCLFRLMLQ DYWENLYQMT LRAAGKSYMV FFIMVIFLGS FYLINLILAV
410 420 430 440 450
VAMAYEEQNQ ATLAEAQEKE AEFQRAVEQL RIQQEQINDE RKASLASQLT
460 470 480 490 500
QNQEAEITDD GDDAIKECNG KAFPLANIRE PSSVKLSTEE QRSDSKSMDS
510 520 530 540 550
KHSVDKPSLK HKAASTMSVF TLEDLEAARR PCPPVWYKFA GFVFKWNCCG
560 570 580 590 600
PWVFLKKWVH FVMMDPFTDL FITLCIILNT LFMSIEHHPM NESFQSLLSA
610 620 630 640 650
GNLVFTTIFA AEMVLKIIAL DPYYYFQQTW NIFDSIIVSL SLLELGLSNM
660 670 680 690 700
QGMSVLRSLR LLRIFKLAKS WPTLNILIKI ICNSVGALGN LTIVLAIIVF
710 720 730 740 750
IFALVGFQLF GKNYKEYVCK ISDDCELPRW HMNDFFHSFL IVFRALCGEW
760 770 780 790 800
IETMWDCMEV GGVPMCLAVY MMVIIIGNLV MLNLFLALLL SSFSSDNLSS
810 820 830 840 850
IEEDDEVNSL QVASERISRA KNWVKIFITG TVQALVLWIQ GKKPPSDDVV
860 870 880 890 900
GEEGDNEGKK DTLPLNYLDG EKIVDGITNC VESPTLNLPI VKGESEIEEE
910 920 930 940 950
GLVDSSDEED TNKKKHALND EDSSVCSTVD YSPSEQDPLA KEEEEEEEEE
960 970 980 990 1000
PEELESKDPE ACFTEKCIWR FPFLDVDITQ GKGKIWWNLR RTCYTIVEHD
1010 1020 1030 1040 1050
YFETFIIFMI LLSSGVLAFE DIYIWRRRVI KVILEYADKV FTYVFIVEML
1060 1070 1080 1090 1100
LKWVAYGFKR YFTDAWCWLD FVIVGASIMG ITSSLLGYEE LGAIKNLRTI
1110 1120 1130 1140 1150
RALRPLRALS RFEGMKVVVR ALLGAIPSIM NVLLVCLMFW LIFSIMGVNL
1160 1170 1180 1190 1200
FAGKFYRCIN TTTDEILPVE EVNNRSDCMA LMYTNEVRWV NLKVNYDNAG
1210 1220 1230 1240 1250
MGYLSLLQVS TFKGWMDIMY AAVDSREVED QPIYEINVYM YLYFVIFIVF
1260 1270 1280 1290 1300
GAFFTLNLFI GVIIDNFNRQ KQKLGGEDLF MTEEQKKYYN AMKKLGSKKA
1310 1320 1330 1340 1350
AKCIPRPSNV VQGVVYDIVT QPFTDIFIMA LICINMVAMM VESEDQSQVK
1360 1370 1380 1390 1400
KDILSQINVI FVIIFTVECL LKLLALRQYF FTVGWNVFDF AVVVISIIGL
1410 1420 1430 1440 1450
LLSDIIEKYF VSPTLFRVIR LARIARVLRL IRAAKGIRTL LFALMMSLPA
1460 1470 1480 1490 1500
LFNIGLLLFL IMFIFSIFGM SNFAYVKKQG GVDDIFNFET FGNSMICLFE
1510 1520 1530 1540 1550
ITTSAGWDGL LLPTLNTGPP DCDPDVENPG TDVRGNCGNP GKGITFFCSY
1560 1570 1580 1590 1600
IILSFLVVVN MYIAIILENF GVAQEESSDL LCEDDFVMFD ETWHKFDVHG
1610 1620 1630 1640 1650
TQFLDYNDLP RFVNALQEPM RIPNPNRHKL AKMDMYVVME DKISYLDVLL
1660 1670 1680 1690 1700
AVTQEVLGDT TEMEAMRLSI QAKFKKDNPS PTFFEPVVTT LRRKEEEWAS
1710 1720 1730 1740 1750
VVIQRAFRQY LLMRAVSHAS FLSQIKHMNE GPKDGVGSQD SLITQKMNAL
1760 1770 1780 1790 1800
YRGNPELTMP LEQQIKPMLD KPRMPSLSVP ETYPIQIPKE VTNEVILHSA
1810 1820
PMVRQNYSYS GAIVVRESIV
Length:1,820
Mass (Da):208,332
Last modified:July 21, 1986 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1B271F626E057864
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X01119 mRNA Translation: CAA25587.1
M22252 mRNA Translation: AAA79960.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A03178 CHEE

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X01119 mRNA Translation: CAA25587.1
M22252 mRNA Translation: AAA79960.1
PIRiA03178 CHEE

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5XSYelectron microscopy4.00A1-1820[»]
SMRiP02719
ModBaseiSearch...
PDBe-KBiSearch...

Protein family/group databases

TCDBi1.A.1.10.19 the voltage-gated ion channel (vic) superfamily

PTM databases

iPTMnetiP02719

Proteomic databases

PRIDEiP02719

Family and domain databases

Gene3Di1.20.120.350, 4 hits
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR001696 Na_channel_asu
IPR010526 Na_trans_assoc
IPR027359 Volt_channel_dom_sf
PfamiView protein in Pfam
PF00520 Ion_trans, 4 hits
PF06512 Na_trans_assoc, 1 hit
PRINTSiPR00170 NACHANNEL

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCNA_ELEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P02719
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: November 13, 2019
This is version 101 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again