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UniProtKB - P02662 (CASA1_BOVIN)

Entry version 161 (23 Feb 2022)
Sequence version 2 (01 Nov 1990)
Previous versions | rss
Add a publicationFeedback
Protein

Alpha-S1-casein

Gene

CSN1S1

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Important role in the capacity of milk to transport calcium phosphate.

1 Publication

Antioxidant peptide has 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity.

1 Publication

Miscellaneous

The B variant sequence is shown.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAntioxidant, Milk protein

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Alpha-S1-casein
Alternative name(s):
Allergen: Bos d 8
Cleaved into the following chain:
Antioxidant peptide
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CSN1S1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBos taurus (Bovine)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9913 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Artiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000009136 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSBTAG00000007695

Vertebrate Gene Nomenclature Database

More...VGNCi		VGNC:27763, CSN1S1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section is used for proteins that cause an allergic reaction in mammals. We usually specify in which species the protein is allergenic.<p><a href='/help/allergenic_properties' target='_top'>More...</a></p>Allergenic propertiesi

Causes an allergic reaction in human. Has six major and 3 minor IgE-binding regions and 5 major and 1 minor IgG-binding regions. Is a cause of cow's milk allergy (CMA).2 Publications

Keywords - Diseasei

Allergen

Protein family/group databases

Allergome; a platform for allergen knowledge

More...Allergomei		10197, Bos d 9.0101
167, Bos d 8
2734, Bos d 9

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 152 PublicationsAdd BLAST15
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000444616 – 214Alpha-S1-caseinAdd BLAST199
<p>This subsection of the 'PTM / Processing' section describes the position and length of an active peptide in the mature protein.<p><a href='/help/peptide' target='_top'>More...</a></p>PeptideiPRO_000033157895 – 105Antioxidant peptideAdd BLAST11

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei56Phosphoserine2 Publications1
Modified residuei61Phosphoserine1 Publication1
Modified residuei63Phosphoserine1 Publication1
Modified residuei79Phosphoserine1 Publication1
Modified residuei81Phosphoserine1 Publication1
Modified residuei82Phosphoserine1 Publication1
Modified residuei83Phosphoserine1 Publication1
Modified residuei90Phosphoserine1 Publication1
Modified residuei130Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P02662

PeptideAtlas

More...PeptideAtlasi		P02662

PRoteomics IDEntifications database

More...PRIDEi		P02662

PTM databases

CarbonylDB database of protein carbonylation sites

More...CarbonylDBi		P02662

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P02662

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Mammary gland specific. Secreted in milk.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSBTAG00000007695, Expressed in milk and 34 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P02662, baseline

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		159482, 3 interactors

Database of interacting proteins

More...DIPi		DIP-29917N

Protein interaction database and analysis system

More...IntActi		P02662, 3 interactors

Molecular INTeraction database

More...MINTi		P02662

STRING: functional protein association networks

More...STRINGi		9913.ENSBTAP00000010119

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati85 – 99Add BLAST15
Repeati125 – 140Add BLAST16

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni195 – 214DisorderedSequence analysisAdd BLAST20

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the alpha-casein family.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502TEWT, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000017378

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_126070_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P02662

Identification of Orthologs from Complete Genome Data

More...OMAi		WYYPPQV

Database of Orthologous Groups

More...OrthoDBi		1478191at2759

TreeFam database of animal gene trees

More...TreeFami		TF340763

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR026999, Alpha-s1_casein
IPR001588, Casein
IPR031305, Casein_CS

The PANTHER Classification System

More...PANTHERi		PTHR10240, PTHR10240, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00363, Casein, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00306, CASEIN_ALPHA_BETA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

P02662-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKLLILTCLV AVALARPKHP IKHQGLPQEV LNENLLRFFV APFPEVFGKE 
        60         70         80         90        100
KVNELSKDIG SESTEDQAME DIKQMEAESI SSSEEIVPNS VEQKHIQKED 
       110        120        130        140        150
VPSERYLGYL EQLLRLKKYK VPQLEIVPNS AEERLHSMKE GIHAQQKEPM 
       160        170        180        190        200
IGVNQELAYF YPELFRQFYQ LDAYPSGAWY YVPLGTQYTD APSFSDIPNP 
       210 
IGSENSEKTT MPLW
Length:214
Mass (Da):24,529
Last modified:November 1, 1990 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF066B5C8AE55828B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A3Q1MJE5A0A3Q1MJE5_BOVIN
Alpha-S1-casein
CSN1S1
200Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q1NG86A0A3Q1NG86_BOVIN
Alpha-S1-casein
CSN1S1
206Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti11 – 12AV → SA in ABW98943 (PubMed:19454699).Curated2
Sequence conflicti42P → L in AAA30429 (PubMed:3022833).Curated1
Sequence conflicti44P → S in ABW98945 (PubMed:19454699).Curated1
Sequence conflicti95H → Q in AAA30478 (PubMed:6897774).Curated1
Sequence conflicti99E → D in ABQ88318 (Ref. 14) Curated1
Sequence conflicti143H → D in AAA30429 (PubMed:3022833).Curated1
Sequence conflicti171L → P in ABW98953 (PubMed:19454699).Curated1
Sequence conflicti203S → L in AAA62707 (PubMed:3838718).Curated1
Sequence conflicti211 – 212MP → IS in AAA30429 (PubMed:3022833).Curated2

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti29 – 41Missing in variant A. Add BLAST13
Natural varianti68A → T in variant D. 1
Natural varianti207E → G in variant C. 1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X00564 mRNA Translation: CAB57792.1
M33123 mRNA Translation: AAA30428.1
M38641 mRNA Translation: AAA30429.1
X59856 Genomic DNA Translation: CAA42516.1
EU221551 Genomic DNA Translation: ABW98936.1
EU221552 Genomic DNA Translation: ABW98937.1
EU221553 Genomic DNA Translation: ABW98938.1
EU221554 Genomic DNA Translation: ABW98939.1
EU221555 Genomic DNA Translation: ABW98940.1
EU221556 Genomic DNA Translation: ABW98941.1
EU221557 Genomic DNA Translation: ABW98942.1
EU221558 Genomic DNA Translation: ABW98943.1
EU221559 Genomic DNA Translation: ABW98944.1
EU221560 Genomic DNA Translation: ABW98945.1
EU221561 Genomic DNA Translation: ABW98946.1
EU221562 Genomic DNA Translation: ABW98947.1
EU221563 Genomic DNA Translation: ABW98948.1
EU221564 Genomic DNA Translation: ABW98949.1
EU221565 Genomic DNA Translation: ABW98950.1
EU221566 Genomic DNA Translation: ABW98951.1
EU221567 Genomic DNA Translation: ABW98952.1
EU221568 Genomic DNA Translation: ABW98953.1
EU221569 Genomic DNA Translation: ABW98954.1
EU221570 Genomic DNA Translation: ABW98955.1
EU221571 Genomic DNA Translation: ABW98956.1
EU221572 Genomic DNA Translation: ABW98957.1
EU221573 Genomic DNA Translation: ABW98958.1
EU221574 Genomic DNA Translation: ABW98959.1
EU221575 Genomic DNA Translation: ABW98960.1
EU221576 Genomic DNA Translation: ABW98961.1
EU221577 Genomic DNA Translation: ABW98962.1
EU221578 Genomic DNA Translation: ABW98963.1
EU221579 Genomic DNA Translation: ABW98964.1
EU221580 Genomic DNA Translation: ABW98965.1
EU221581 Genomic DNA Translation: ABW98966.1
BC109618 mRNA Translation: AAI09619.1
K01084 mRNA Translation: AAA30478.1
EF538766 Genomic DNA Translation: ABQ88318.1
M38658 mRNA Translation: AAA62707.1
AH007360 Genomic DNA Translation: AAD14099.1
D00412 mRNA Translation: BAA00313.1

Protein sequence database of the Protein Information Resource

More...PIRi		S22575, KABOSB
S72220

NCBI Reference Sequences

More...RefSeqi		NP_851372.1, NM_181029.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSBTAT00000010119; ENSBTAP00000010119; ENSBTAG00000007695
ENSBTAT00000084279; ENSBTAP00000071217; ENSBTAG00000007695

Database of genes from NCBI RefSeq genomes

More...GeneIDi		282208

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		bta:282208

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Worthington enzyme manual
Protein Spotlight

Of buttons, digestion and glue - Issue 16 of November 2001

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X00564 mRNA Translation: CAB57792.1
M33123 mRNA Translation: AAA30428.1
M38641 mRNA Translation: AAA30429.1
X59856 Genomic DNA Translation: CAA42516.1
EU221551 Genomic DNA Translation: ABW98936.1
EU221552 Genomic DNA Translation: ABW98937.1
EU221553 Genomic DNA Translation: ABW98938.1
EU221554 Genomic DNA Translation: ABW98939.1
EU221555 Genomic DNA Translation: ABW98940.1
EU221556 Genomic DNA Translation: ABW98941.1
EU221557 Genomic DNA Translation: ABW98942.1
EU221558 Genomic DNA Translation: ABW98943.1
EU221559 Genomic DNA Translation: ABW98944.1
EU221560 Genomic DNA Translation: ABW98945.1
EU221561 Genomic DNA Translation: ABW98946.1
EU221562 Genomic DNA Translation: ABW98947.1
EU221563 Genomic DNA Translation: ABW98948.1
EU221564 Genomic DNA Translation: ABW98949.1
EU221565 Genomic DNA Translation: ABW98950.1
EU221566 Genomic DNA Translation: ABW98951.1
EU221567 Genomic DNA Translation: ABW98952.1
EU221568 Genomic DNA Translation: ABW98953.1
EU221569 Genomic DNA Translation: ABW98954.1
EU221570 Genomic DNA Translation: ABW98955.1
EU221571 Genomic DNA Translation: ABW98956.1
EU221572 Genomic DNA Translation: ABW98957.1
EU221573 Genomic DNA Translation: ABW98958.1
EU221574 Genomic DNA Translation: ABW98959.1
EU221575 Genomic DNA Translation: ABW98960.1
EU221576 Genomic DNA Translation: ABW98961.1
EU221577 Genomic DNA Translation: ABW98962.1
EU221578 Genomic DNA Translation: ABW98963.1
EU221579 Genomic DNA Translation: ABW98964.1
EU221580 Genomic DNA Translation: ABW98965.1
EU221581 Genomic DNA Translation: ABW98966.1
BC109618 mRNA Translation: AAI09619.1
K01084 mRNA Translation: AAA30478.1
EF538766 Genomic DNA Translation: ABQ88318.1
M38658 mRNA Translation: AAA62707.1
AH007360 Genomic DNA Translation: AAD14099.1
D00412 mRNA Translation: BAA00313.1
PIRiS22575, KABOSB
S72220
RefSeqiNP_851372.1, NM_181029.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi159482, 3 interactors
DIPiDIP-29917N
IntActiP02662, 3 interactors
MINTiP02662
STRINGi9913.ENSBTAP00000010119

Protein family/group databases

Allergomei10197, Bos d 9.0101
167, Bos d 8
2734, Bos d 9

PTM databases

CarbonylDBiP02662
iPTMnetiP02662

Proteomic databases

PaxDbiP02662
PeptideAtlasiP02662
PRIDEiP02662

Genome annotation databases

EnsembliENSBTAT00000010119; ENSBTAP00000010119; ENSBTAG00000007695
ENSBTAT00000084279; ENSBTAP00000071217; ENSBTAG00000007695
GeneIDi282208
KEGGibta:282208

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		1446
VEuPathDBiHostDB:ENSBTAG00000007695
VGNCiVGNC:27763, CSN1S1

Phylogenomic databases

eggNOGiENOG502TEWT, Eukaryota
GeneTreeiENSGT00390000017378
HOGENOMiCLU_126070_0_0_1
InParanoidiP02662
OMAiWYYPPQV
OrthoDBi1478191at2759
TreeFamiTF340763

Miscellaneous databases

Protein Ontology

More...PROi		PR:P02662

Gene expression databases

BgeeiENSBTAG00000007695, Expressed in milk and 34 other tissues
ExpressionAtlasiP02662, baseline

Family and domain databases

InterProiView protein in InterPro
IPR026999, Alpha-s1_casein
IPR001588, Casein
IPR031305, Casein_CS
PANTHERiPTHR10240, PTHR10240, 1 hit
PfamiView protein in Pfam
PF00363, Casein, 1 hit
PROSITEiView protein in PROSITE
PS00306, CASEIN_ALPHA_BETA, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCASA1_BOVIN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P02662
Secondary accession number(s): A5YK80
, A8WCP1, A8WCP2, A8WCP3, A8WCP4, A8WCP5, A8WCP6, A8WCP7, A8WCP8, A8WCP9, A8WCQ0, A8WCQ1, A8WCQ2, A8WCQ3, A8WCQ4, A8WCQ5, A8WCQ6, A8WCQ7, A8WCQ8, A8WCQ9, A8WCR0, A8WCR1, A8WCR2, A8WCR3, A8WCR4, A8WCR5, A8WCR6, A8WCR7, A8WCR8, A8WCR9, A8WCS0, A8WCS1, Q28048, Q28069, Q32LE8, Q7M2U6, Q9TRH5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: November 1, 1990
Last modified: February 23, 2022
This is version 161 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
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