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UniProtKB - P02633 (S100G_BOVIN)
Protein
Protein S100-G
Gene
S100G
Organism
Bos taurus (Bovine)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 26 | Calcium 1; low affinityCurated | 1 | |
Metal bindingi | 31 | Calcium 1; low affinityCurated | 1 | |
Metal bindingi | 58 | Calcium 2; high affinityPROSITE-ProRule annotation | 1 | |
Metal bindingi | 60 | Calcium 2; high affinityPROSITE-ProRule annotation | 1 | |
Metal bindingi | 62 | Calcium 2; high affinityPROSITE-ProRule annotation | 1 | |
Metal bindingi | 64 | Calcium 2; high affinityPROSITE-ProRule annotation | 1 | |
Metal bindingi | 69 | Calcium 2; high affinityPROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- calcium-dependent protein binding Source: GO_Central
- calcium ion binding Source: GO_Central
- vitamin D binding Source: UniProtKB-KW
Keywordsi
Ligand | Calcium, Metal-binding, Vitamin D |
Names & Taxonomyi
Protein namesi | Recommended name: Protein S100-GAlternative name(s): Calbindin-D9k S100 calcium-binding protein G Vitamin D-dependent calcium-binding protein, intestinal Short name: CABP |
Gene namesi | Name:S100G Synonyms:CALB3, S100D |
Organismi | Bos taurus (Bovine) |
Taxonomic identifieri | 9913 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Artiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | HostDB:ENSBTAG00000017020 |
VGNCi | VGNC:34249, S100G |
Subcellular locationi
Extracellular region or secreted
- extracellular space Source: GO_Central
Plasma Membrane
- apical plasma membrane Source: Ensembl
- basolateral plasma membrane Source: Ensembl
Other locations
- cytoplasm Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | Removed | |||
ChainiPRO_0000144026 | 2 – 79 | Protein S100-GAdd BLAST | 78 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylserine1 Publication | 1 | |
Modified residuei | 42 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
PaxDbi | P02633 |
PTM databases
iPTMneti | P02633 |
Expressioni
Gene expression databases
Bgeei | ENSBTAG00000017020, Expressed in placenta and 87 other tissues |
Interactioni
GO - Molecular functioni
- calcium-dependent protein binding Source: GO_Central
Protein-protein interaction databases
STRINGi | 9913.ENSBTAP00000022630 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
AlphaFoldDBi | P02633 |
BMRBi | P02633 |
SMRi | P02633 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P02633 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 13 – 48 | EF-hand 1CuratedAdd BLAST | 36 | |
Domaini | 45 – 79 | EF-hand 2PROSITE-ProRule annotationAdd BLAST | 35 |
Sequence similaritiesi
Belongs to the S-100 family.Curated
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | ENOG502T3Z3, Eukaryota |
GeneTreei | ENSGT00530000064238 |
HOGENOMi | CLU_138624_4_0_1 |
InParanoidi | P02633 |
OMAi | QKYAAKE |
OrthoDBi | 1558629at2759 |
TreeFami | TF332727 |
Family and domain databases
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom IPR001751, S100/CaBP7/8-like_CS IPR013787, S100_Ca-bd_sub IPR028489, S100G |
PANTHERi | PTHR11639:SF73, PTHR11639:SF73, 1 hit |
Pfami | View protein in Pfam PF00036, EF-hand_1, 1 hit PF01023, S_100, 1 hit |
SMARTi | View protein in SMART SM00054, EFh, 1 hit SM01394, S_100, 1 hit |
SUPFAMi | SSF47473, SSF47473, 1 hit |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 1 hit PS50222, EF_HAND_2, 1 hit PS00303, S100_CABP, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P02633-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSAKKSPEEL KGIFEKYAAK EGDPNQLSKE ELKLLLQTEF PSLLKGPSTL
60 70
DELFEELDKN GDGEVSFEEF QVLVKKISQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M18344 mRNA Translation: AAA30420.1 BC118480 mRNA Translation: AAI18481.1 |
PIRi | A40151, KLBOI |
RefSeqi | NP_776682.1, NM_174257.3 |
Genome annotation databases
Ensembli | ENSBTAT00000022630; ENSBTAP00000022630; ENSBTAG00000017020 |
GeneIDi | 281658 |
KEGGi | bta:281658 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M18344 mRNA Translation: AAA30420.1 BC118480 mRNA Translation: AAI18481.1 |
PIRi | A40151, KLBOI |
RefSeqi | NP_776682.1, NM_174257.3 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1B1G | NMR | - | A | 5-79 | [»] | |
1BOC | NMR | - | A | 5-79 | [»] | |
1BOD | NMR | - | A | 5-79 | [»] | |
1CDN | NMR | - | A | 5-79 | [»] | |
1CLB | NMR | - | A | 5-79 | [»] | |
1D1O | NMR | - | A | 5-79 | [»] | |
1HT9 | X-ray | 1.76 | A/B | 5-79 | [»] | |
1IG5 | X-ray | 1.50 | A | 5-79 | [»] | |
1IGV | X-ray | 1.85 | A | 5-79 | [»] | |
1KCY | NMR | - | A | 5-79 | [»] | |
1KQV | NMR | - | A | 1-79 | [»] | |
1KSM | NMR | - | A | 1-79 | [»] | |
1N65 | NMR | - | A | 5-79 | [»] | |
1QX2 | X-ray | 1.44 | A/B | 5-79 | [»] | |
1RT0 | NMR | - | A | 58-69 | [»] | |
2BCA | NMR | - | A | 5-79 | [»] | |
2BCB | NMR | - | A | 5-79 | [»] | |
2MAZ | NMR | - | A | 5-79 | [»] | |
3ICB | X-ray | 2.30 | A | 5-79 | [»] | |
4ICB | X-ray | 1.60 | A | 5-79 | [»] | |
AlphaFoldDBi | P02633 | |||||
BMRBi | P02633 | |||||
SMRi | P02633 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 9913.ENSBTAP00000022630 |
PTM databases
iPTMneti | P02633 |
Proteomic databases
PaxDbi | P02633 |
Genome annotation databases
Ensembli | ENSBTAT00000022630; ENSBTAP00000022630; ENSBTAG00000017020 |
GeneIDi | 281658 |
KEGGi | bta:281658 |
Organism-specific databases
CTDi | 795 |
VEuPathDBi | HostDB:ENSBTAG00000017020 |
VGNCi | VGNC:34249, S100G |
Phylogenomic databases
eggNOGi | ENOG502T3Z3, Eukaryota |
GeneTreei | ENSGT00530000064238 |
HOGENOMi | CLU_138624_4_0_1 |
InParanoidi | P02633 |
OMAi | QKYAAKE |
OrthoDBi | 1558629at2759 |
TreeFami | TF332727 |
Miscellaneous databases
EvolutionaryTracei | P02633 |
Gene expression databases
Bgeei | ENSBTAG00000017020, Expressed in placenta and 87 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom IPR001751, S100/CaBP7/8-like_CS IPR013787, S100_Ca-bd_sub IPR028489, S100G |
PANTHERi | PTHR11639:SF73, PTHR11639:SF73, 1 hit |
Pfami | View protein in Pfam PF00036, EF-hand_1, 1 hit PF01023, S_100, 1 hit |
SMARTi | View protein in SMART SM00054, EFh, 1 hit SM01394, S_100, 1 hit |
SUPFAMi | SSF47473, SSF47473, 1 hit |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 1 hit PS50222, EF_HAND_2, 1 hit PS00303, S100_CABP, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | S100G_BOVIN | |
Accessioni | P02633Primary (citable) accession number: P02633 Secondary accession number(s): Q17Q94 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 21, 1986 |
Last sequence update: | January 23, 2007 | |
Last modified: | May 25, 2022 | |
This is version 157 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families