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Protein

Protein S100-G

Gene

S100G

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi18 – 311; low affinityAdd BLAST14
Calcium bindingi58 – 692; high affinityAdd BLAST12

GO - Molecular functioni

Keywordsi

LigandCalcium, Metal-binding, Vitamin D

Names & Taxonomyi

Protein namesi
Recommended name:
Protein S100-G
Alternative name(s):
Calbindin-D9k
S100 calcium-binding protein G
Vitamin D-dependent calcium-binding protein, intestinal
Short name:
CABP
Cleaved into the following chain:
Gene namesi
Name:S100G
Synonyms:CALB3, S100D
OrganismiSus scrofa (Pig)
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome X

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001440292 – 79Protein S100-GAdd BLAST78
ChainiPRO_00002758993 – 79Protein S100-G, minor isoformAdd BLAST77

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserine1 Publication1
Modified residuei3N-acetylalanine; in Protein S100-G, minor isoform1 Publication1
Modified residuei42PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiP02632
PeptideAtlasiP02632
PRIDEiP02632

PTM databases

iPTMnetiP02632

Expressioni

Gene expression databases

ExpressionAtlasiP02632 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000012930

Structurei

Secondary structure

179
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi7 – 18Combined sources12
Beta strandi21 – 23Combined sources3
Helixi29 – 39Combined sources11
Helixi52 – 56Combined sources5
Beta strandi61 – 66Combined sources6
Helixi67 – 77Combined sources11

3D structure databases

ProteinModelPortaliP02632
SMRiP02632
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP02632

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 48EF-hand 1PROSITE-ProRule annotationAdd BLAST36
Domaini45 – 79EF-hand 2PROSITE-ProRule annotationAdd BLAST35

Sequence similaritiesi

Belongs to the S-100 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG410J1CR Eukaryota
ENOG4111C34 LUCA
GeneTreeiENSGT00530000064238
HOGENOMiHOG000246968
HOVERGENiHBG001479
InParanoidiP02632
KOiK14734

Family and domain databases

CDDicd00213 S-100, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR034325 S-100_dom
IPR001751 S100/CaBP-9k_CS
IPR013787 S100_Ca-bd_sub
IPR028489 S100G
PANTHERiPTHR11639:SF73 PTHR11639:SF73, 1 hit
PfamiView protein in Pfam
PF00036 EF-hand_1, 1 hit
PF01023 S_100, 1 hit
SMARTiView protein in SMART
SM00054 EFh, 1 hit
SM01394 S_100, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 1 hit
PS00303 S100_CABP, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P02632-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAQKSPAEL KSIFEKYAAK EGDPNQLSKE ELKQLIQAEF PSLLKGPRTL
60 70
DDLFQELDKN GDGEVSFEEF QVLVKKISQ
Length:79
Mass (Da):8,929
Last modified:January 23, 2007 - v3
Checksum:iE8AB53BF23BD2D57
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti62D → N AA sequence (PubMed:476518).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L13068 mRNA Translation: AAA81524.1
PIRiA56802 KLPGI
RefSeqiNP_999305.1, NM_214140.2
UniGeneiSsc.429

Genome annotation databases

EnsembliENSSSCT00000049484; ENSSSCP00000044898; ENSSSCG00000012147
GeneIDi397265
KEGGissc:397265

Similar proteinsi

Entry informationi

Entry nameiS100G_PIG
AccessioniPrimary (citable) accession number: P02632
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 139 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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