UniProtKB - P02621 (PRVB_MERMR)
Protein
Parvalbumin beta
Gene
N/A
Organism
Merlangius merlangus (Whiting) (Gadus merlangus)
Status
Functioni
In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.
Miscellaneous
This parvalbumin has an isoelectric point of 4.50.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 51 | Calcium 1Combined sources1 Publication | 1 | |
Metal bindingi | 53 | Calcium 1Combined sources1 Publication | 1 | |
Metal bindingi | 55 | Calcium 1Combined sources1 Publication | 1 | |
Metal bindingi | 57 | Calcium 1; via carbonyl oxygenCombined sources1 Publication | 1 | |
Metal bindingi | 59 | Calcium 1Combined sources1 Publication | 1 | |
Metal bindingi | 62 | Calcium 1Combined sources1 Publication | 1 | |
Metal bindingi | 90 | Calcium 2Combined sources1 Publication | 1 | |
Metal bindingi | 92 | Calcium 2Combined sources1 Publication | 1 | |
Metal bindingi | 94 | Calcium 2Combined sources1 Publication | 1 | |
Metal bindingi | 96 | Calcium 2; via carbonyl oxygenCombined sources1 Publication | 1 | |
Metal bindingi | 101 | Calcium 2Combined sources1 Publication | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Calcium bindingi | 51 – 62 | 1PROSITE-ProRule annotationCombined sources1 PublicationAdd BLAST | 12 | |
Calcium bindingi | 90 – 101 | 2PROSITE-ProRule annotationCombined sources1 PublicationAdd BLAST | 12 |
GO - Molecular functioni
- calcium ion binding Source: InterPro
Keywordsi
Molecular function | Muscle protein |
Ligand | Calcium, Metal-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Parvalbumin beta |
Organismi | Merlangius merlangus (Whiting) (Gadus merlangus) |
Taxonomic identifieri | 8058 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Neoteleostei › Acanthomorphata › Zeiogadaria › Gadariae › Gadiformes › Gadoidei › Gadidae › Merlangius |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000073615 | 1 – 108 | Parvalbumin betaAdd BLAST | 108 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1 | N-acetylalanine1 Publication | 1 | |
Disulfide bondi | 11 ↔ 33 | Combined sources1 Publication |
Keywords - PTMi
Acetylation, Disulfide bondPTM databases
iPTMneti | P02621 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P02621 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P02621 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 38 – 73 | EF-hand 1PROSITE-ProRule annotationAdd BLAST | 36 | |
Domaini | 77 – 108 | EF-hand 2PROSITE-ProRule annotationAdd BLAST | 32 |
Sequence similaritiesi
Belongs to the parvalbumin family.Curated
Keywords - Domaini
RepeatFamily and domain databases
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom IPR008080, Parvalbumin |
PANTHERi | PTHR11653, PTHR11653, 1 hit |
Pfami | View protein in Pfam PF13499, EF-hand_7, 1 hit |
SMARTi | View protein in SMART SM00054, EFh, 2 hits |
SUPFAMi | SSF47473, SSF47473, 1 hit |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 2 hits PS50222, EF_HAND_2, 2 hits |
i Sequence
Sequence statusi: Complete.
P02621-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
AFAGILADAD CAAAVKACEA ADSFSYKAFF AKCGLSGKSA DDIKKAFVFI
60 70 80 90 100
DQDKSGFIEE DELKLFLQVF KAGARALTDA ETKAFLKAGD SDGDGAIGVE
EWVALVKA
Sequence databases
PIRi | A03056, PVWI |
Similar proteinsi
Cross-referencesi
Sequence databases
PIRi | A03056, PVWI |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1A75 | X-ray | 1.90 | A/B | 1-108 | [»] | |
SMRi | P02621 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
PTM databases
iPTMneti | P02621 |
Miscellaneous databases
EvolutionaryTracei | P02621 |
Family and domain databases
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom IPR008080, Parvalbumin |
PANTHERi | PTHR11653, PTHR11653, 1 hit |
Pfami | View protein in Pfam PF13499, EF-hand_7, 1 hit |
SMARTi | View protein in SMART SM00054, EFh, 2 hits |
SUPFAMi | SSF47473, SSF47473, 1 hit |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 2 hits PS50222, EF_HAND_2, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PRVB_MERMR | |
Accessioni | P02621Primary (citable) accession number: P02621 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 21, 1986 |
Last sequence update: | July 15, 1998 | |
Last modified: | December 11, 2019 | |
This is version 110 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencingDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families