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Protein

Myoglobin

Gene

MB

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi65Iron (heme distal ligand)1 Publication1
Metal bindingi94Iron (heme proximal ligand)Combined sources1 Publication1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMuscle protein
Biological processOxygen transport, Transport
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-8981607 Intracellular oxygen transport

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.A.107.1.3 the pore-forming globin (globin) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Myoglobin
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MB
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000198125.12

Human Gene Nomenclature Database

More...
HGNCi
HGNC:6915 MB

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
160000 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P02144

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
4151

Open Targets

More...
OpenTargetsi
ENSG00000198125

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA30658

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL2406892

Drug and drug target database

More...
DrugBanki
DB02671 1-Methylimidazole
DB03385 4-Methylimidazole
DB02379 Beta-D-Glucose
DB02073 Biliverdine Ix Alpha
DB03399 Ethyl Isocyanide
DB04337 Methyl Isocyanide
DB02396 Methylethylamine
DB01826 N-Butyl Isocyanide
DB04050 N-Propyl Isocyanide
DB02646 Nitrosoethane
DB01710 Porphyrin Fe(Iii)
DB02528 Tetrazolyl Histidine

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MB

Domain mapping of disease mutations (DMDM)

More...
DMDMi
127661

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved2 Publications
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000533032 – 154MyoglobinAdd BLAST153

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei4PhosphoserineBy similarity1
Modified residuei68PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P02144

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P02144

PeptideAtlas

More...
PeptideAtlasi
P02144

PRoteomics IDEntifications database

More...
PRIDEi
P02144

ProteomicsDB human proteome resource

More...
ProteomicsDBi
12686
51517

2D gel databases

University College Dublin 2-DE Proteome Database

More...
UCD-2DPAGEi
P02144

PTM databases

CarbonylDB database of protein carbonylation sites

More...
CarbonylDBi
P02144

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P02144

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P02144

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000198125 Expressed in 152 organ(s), highest expression level in heart right ventricle

CleanEx database of gene expression profiles

More...
CleanExi
HS_MB

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P02144 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P02144 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB000060
HPA003123

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
110321, 7 interactors

Protein interaction database and analysis system

More...
IntActi
P02144, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000352835

Chemistry databases

BindingDB database of measured binding affinities

More...
BindingDBi
P02144

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1154
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P02144

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P02144

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3378 Eukaryota
COG1018 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160809

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000070111

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG107340

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P02144

KEGG Orthology (KO)

More...
KOi
K21892

Identification of Orthologs from Complete Genome Data

More...
OMAi
LFRNDIA

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0OAO

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P02144

TreeFam database of animal gene trees

More...
TreeFami
TF332967

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.490.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
IPR002335 Myoglobin

The PANTHER Classification System

More...
PANTHERi
PTHR11442:SF5 PTHR11442:SF5, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00042 Globin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00613 MYOGLOBIN

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46458 SSF46458, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01033 GLOBIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

P02144-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGLSDGEWQL VLNVWGKVEA DIPGHGQEVL IRLFKGHPET LEKFDKFKHL
60 70 80 90 100
KSEDEMKASE DLKKHGATVL TALGGILKKK GHHEAEIKPL AQSHATKHKI
110 120 130 140 150
PVKYLEFISE CIIQVLQSKH PGDFGADAQG AMNKALELFR KDMASNYKEL

GFQG
Length:154
Mass (Da):17,184
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF6A41F19A525F09C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B0QYF8B0QYF8_HUMAN
Myoglobin
MB
143Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B0QYF7B0QYF7_HUMAN
Myoglobin
MB
74Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F2Z337F2Z337_HUMAN
Myoglobin
MB
77Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8WVH6Q8WVH6_HUMAN
Myoglobin
MB
99Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F2Z2F1F2Z2F1_HUMAN
Myoglobin
MB
106Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti106E → Q in AAX84516 (Ref. 5) Curated1
Sequence conflicti129Q → E in AAA59595 (PubMed:2989088).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_00318055E → K1 PublicationCorresponds to variant dbSNP:rs145465287Ensembl.1
Natural variantiVAR_003181134K → N1 PublicationCorresponds to variant dbSNP:rs766095327Ensembl.1
Natural variantiVAR_003182140R → Q1 PublicationCorresponds to variant dbSNP:rs142225854Ensembl.1
Natural variantiVAR_003183140R → W1 PublicationCorresponds to variant dbSNP:rs767663245Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X00371, X00372, X00373 Genomic DNA Translation: CAA25109.1
M14603, M10090, M14602 Genomic DNA Translation: AAA59595.1
CR456516 mRNA Translation: CAG30402.1
CR541949 mRNA Translation: CAG46747.1
DQ003030 Genomic DNA Translation: AAX84516.1
AL022334, AL049747 Genomic DNA Translation: CAI21837.1
BC014547 mRNA Translation: AAH14547.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13917.1

Protein sequence database of the Protein Information Resource

More...
PIRi
I53991 MYHU

NCBI Reference Sequences

More...
RefSeqi
NP_005359.1, NM_005368.2
NP_976311.1, NM_203377.1
NP_976312.1, NM_203378.1
XP_005261662.1, XM_005261605.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.517586

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000359787; ENSP00000352835; ENSG00000198125
ENST00000397326; ENSP00000380489; ENSG00000198125
ENST00000397328; ENSP00000380491; ENSG00000198125
ENST00000406324; ENSP00000384239; ENSG00000198125

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4151

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:4151

UCSC genome browser

More...
UCSCi
uc003anz.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

NIEHS-SNPs

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X00371, X00372, X00373 Genomic DNA Translation: CAA25109.1
M14603, M10090, M14602 Genomic DNA Translation: AAA59595.1
CR456516 mRNA Translation: CAG30402.1
CR541949 mRNA Translation: CAG46747.1
DQ003030 Genomic DNA Translation: AAX84516.1
AL022334, AL049747 Genomic DNA Translation: CAI21837.1
BC014547 mRNA Translation: AAH14547.1
CCDSiCCDS13917.1
PIRiI53991 MYHU
RefSeqiNP_005359.1, NM_005368.2
NP_976311.1, NM_203377.1
NP_976312.1, NM_203378.1
XP_005261662.1, XM_005261605.2
UniGeneiHs.517586

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3RGKX-ray1.65A2-154[»]
ProteinModelPortaliP02144
SMRiP02144
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi110321, 7 interactors
IntActiP02144, 2 interactors
STRINGi9606.ENSP00000352835

Chemistry databases

BindingDBiP02144
ChEMBLiCHEMBL2406892
DrugBankiDB02671 1-Methylimidazole
DB03385 4-Methylimidazole
DB02379 Beta-D-Glucose
DB02073 Biliverdine Ix Alpha
DB03399 Ethyl Isocyanide
DB04337 Methyl Isocyanide
DB02396 Methylethylamine
DB01826 N-Butyl Isocyanide
DB04050 N-Propyl Isocyanide
DB02646 Nitrosoethane
DB01710 Porphyrin Fe(Iii)
DB02528 Tetrazolyl Histidine

Protein family/group databases

TCDBi1.A.107.1.3 the pore-forming globin (globin) family

PTM databases

CarbonylDBiP02144
iPTMnetiP02144
PhosphoSitePlusiP02144

Polymorphism and mutation databases

BioMutaiMB
DMDMi127661

2D gel databases

UCD-2DPAGEiP02144

Proteomic databases

MaxQBiP02144
PaxDbiP02144
PeptideAtlasiP02144
PRIDEiP02144
ProteomicsDBi12686
51517

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
4151
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000359787; ENSP00000352835; ENSG00000198125
ENST00000397326; ENSP00000380489; ENSG00000198125
ENST00000397328; ENSP00000380491; ENSG00000198125
ENST00000406324; ENSP00000384239; ENSG00000198125
GeneIDi4151
KEGGihsa:4151
UCSCiuc003anz.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
4151
DisGeNETi4151
EuPathDBiHostDB:ENSG00000198125.12

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MB
HGNCiHGNC:6915 MB
HPAiCAB000060
HPA003123
MIMi160000 gene
neXtProtiNX_P02144
OpenTargetsiENSG00000198125
PharmGKBiPA30658

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3378 Eukaryota
COG1018 LUCA
GeneTreeiENSGT00940000160809
HOGENOMiHOG000070111
HOVERGENiHBG107340
InParanoidiP02144
KOiK21892
OMAiLFRNDIA
OrthoDBiEOG091G0OAO
PhylomeDBiP02144
TreeFamiTF332967

Enzyme and pathway databases

ReactomeiR-HSA-8981607 Intracellular oxygen transport

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
MB human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
Myoglobin

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
4151

Protein Ontology

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PROi
PR:P02144

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000198125 Expressed in 152 organ(s), highest expression level in heart right ventricle
CleanExiHS_MB
ExpressionAtlasiP02144 baseline and differential
GenevisibleiP02144 HS

Family and domain databases

Gene3Di1.10.490.10, 1 hit
InterProiView protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
IPR002335 Myoglobin
PANTHERiPTHR11442:SF5 PTHR11442:SF5, 1 hit
PfamiView protein in Pfam
PF00042 Globin, 1 hit
PRINTSiPR00613 MYOGLOBIN
SUPFAMiSSF46458 SSF46458, 1 hit
PROSITEiView protein in PROSITE
PS01033 GLOBIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMYG_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P02144
Secondary accession number(s): Q52H51, Q5THY7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: December 5, 2018
This is version 181 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  6. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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