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Entry version 179 (16 Oct 2019)
Sequence version 2 (23 Jan 2007)
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Protein

Hemoglobin subunit beta-1

Gene

Hbb-b1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in oxygen transport from the lung to the various peripheral tissues.

Miscellaneous

The D-major sequence is shown. See also the entry for the beta D and P-minor chain.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi64Iron (heme distal ligand)By similarity1
Metal bindingi93Iron (heme proximal ligand)Combined sources1 Publication1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processOxygen transport, Transport
LigandHeme, Iron, Metal-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Hemoglobin subunit beta-1
Alternative name(s):
Beta-1-globin
Hemoglobin beta-1 chain
Hemoglobin beta-major chain
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Hbb-b1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:96021 Hbb-b1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000530242 – 147Hemoglobin subunit beta-1Add BLAST146

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylvalineBy similarity1
Modified residuei18N6-succinyllysineCombined sources1
Modified residuei21PhosphoserineCombined sources1
Modified residuei45PhosphoserineBy similarity1
Modified residuei51PhosphoserineBy similarity1
Modified residuei60N6-succinyllysineBy similarity1
Modified residuei105Asymmetric dimethylarginineBy similarity1
Modified residuei124PhosphothreonineBy similarity1

Keywords - PTMi

Acetylation, Methylation, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P02088

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P02088

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P02088

PeptideAtlas

More...
PeptideAtlasi
P02088

PRoteomics IDEntifications database

More...
PRIDEi
P02088

2D gel databases

REPRODUCTION-2DPAGE

More...
REPRODUCTION-2DPAGEi
IPI00553333
P02088

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...
SWISS-2DPAGEi
P02088

PTM databases

CarbonylDB database of protein carbonylation sites

More...
CarbonylDBi
P02088

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P02088

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P02088

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P02088

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Red blood cells.

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Heterotetramer of two alpha chains and two beta chains.

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
1639840, 1 interactor
200219, 5 interactors
3405151, 1 interactor

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-2922 Hemoglobin HbA complex, variant HBB1

Protein interaction database and analysis system

More...
IntActi
P02088, 11 interactors

Molecular INTeraction database

More...
MINTi
P02088

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000095794

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1147
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P02088

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P02088

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3378 Eukaryota
COG1018 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P02088

KEGG Orthology (KO)

More...
KOi
K13823

Database of Orthologous Groups

More...
OrthoDBi
1370439at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P02088

Family and domain databases

Conserved Domains Database

More...
CDDi
cd08925 Hb-beta_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.490.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
IPR002337 Haemoglobin_b

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00042 Globin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00814 BETAHAEM

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46458 SSF46458, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01033 GLOBIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P02088-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVHLTDAEKA AVSCLWGKVN SDEVGGEALG RLLVVYPWTQ RYFDSFGDLS
60 70 80 90 100
SASAIMGNAK VKAHGKKVIT AFNDGLNHLD SLKGTFASLS ELHCDKLHVD
110 120 130 140
PENFRLLGNM IVIVLGHHLG KDFTPAAQAA FQKVVAGVAT ALAHKYH
Length:147
Mass (Da):15,840
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8190EAEEFD9036A3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti15L → Q in BAB27362 (PubMed:16141072).Curated1
Sequence conflicti39T → A in BAB29299 (PubMed:16141072).Curated1
Sequence conflicti63A → T in BAB27237 (PubMed:16141072).Curated1
Sequence conflicti91E → Q (PubMed:482942).Curated1
Sequence conflicti109N → S in BAB29299 (PubMed:16141072).Curated1

<p>This subsection of the ‘Sequence’ section provides information on polymorphic variants. If the variant is associated with a disease state, the description of the latter can be found in the <a href="http://www.uniprot.org/manual/involvement_in_disease">'Involvement in disease'</a> subsection.<p><a href='/help/polymorphism' target='_top'>More...</a></p>Polymorphismi

Inbred mouse strains possess 1 of 4 alleles at the HBB locus: D (diffuse), S (single), P and W1. The D and P alleles are actually closely linked doublets that coordinately express a major and a minor chain, the minor chain being slightly different in the two alleles. The S allele produces only 1 chain, it is characteristic of North American wild mice. The W1 allele is observed mainly in Northwestern China.3 Publications

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti14C → G in allele S and allele W1. 3 Publications1
Natural varianti21S → A in allele S. 2 Publications1
Natural varianti74D → E in allele W1. 2 Publications1
Natural varianti135V → M in allele W1. 2 Publications1
Natural varianti140T → A in allele S. 2 Publications1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X14061 Genomic DNA Translation: CAA32224.1
J00413 Genomic DNA Translation: AAA37791.1
AB020013 mRNA Translation: BAA77353.1
AB020015 mRNA Translation: BAA77355.1
AK002258 mRNA Translation: BAB21971.1
AK002394 mRNA Translation: BAB22067.1
AK003096 mRNA Translation: BAB22562.1
AK003472 mRNA Translation: BAB22806.1
AK005442 mRNA Translation: BAB24036.1
AK005490 mRNA Translation: BAB24075.1
AK005496 mRNA Translation: BAB24080.1
AK010873 mRNA Translation: BAB27237.1
AK010902 mRNA Translation: BAB27255.1
AK010980 mRNA Translation: BAB27302.1
AK010981 mRNA Translation: BAB27303.1
AK010991 mRNA Translation: BAB27310.1
AK010993 mRNA Translation: BAB27312.1
AK011006 mRNA Translation: BAB27325.1
AK011013 mRNA Translation: BAB27331.1
AK011016 mRNA Translation: BAB27334.1
AK011027 mRNA Translation: BAB27343.1
AK011033 mRNA Translation: BAB27347.1
AK011050 mRNA Translation: BAB27360.1
AK011052 mRNA Translation: BAB27361.1
AK011053 mRNA Translation: BAB27362.1
AK011057 mRNA Translation: BAB27365.1
AK011067 mRNA Translation: BAB27374.1
AK011069 mRNA Translation: BAB27376.1
AK011075 mRNA Translation: BAB27380.1
AK011077 mRNA Translation: BAB27382.1
AK011083 mRNA Translation: BAB27387.1
AK011102 mRNA Translation: BAB27399.1
AK012551 mRNA Translation: BAB28311.1
AK014364 mRNA Translation: BAB29299.1
AK027903 mRNA Translation: BAC25655.1
AK027904 mRNA Translation: BAC25656.1
AK028067 mRNA Translation: BAC25734.1
AK088149 mRNA Translation: BAC40173.1
AK133714 mRNA Translation: BAE21794.1
AK147001 mRNA Translation: BAE27598.1
AK160629 mRNA Translation: BAE35926.1
AK161021 mRNA Translation: BAE36152.1
AK165490 mRNA Translation: BAE38217.1
AK167615 mRNA Translation: BAE39668.1
AK168412 mRNA Translation: BAE40327.1
AK168477 mRNA Translation: BAE40366.1
AK168562 mRNA Translation: BAE40435.1
AK168584 mRNA Translation: BAE40453.1
AK168819 mRNA Translation: BAE40646.1
AK168826 mRNA Translation: BAE40653.1
AK168846 mRNA Translation: BAE40669.1
M19236 mRNA Translation: AAA37788.1
M10828 Genomic DNA Translation: AAA37786.1
M10830, M10829 Genomic DNA Translation: AAA37787.1
M10688 Genomic DNA Translation: AAA37790.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A90790 HBMS

NCBI Reference Sequences

More...
RefSeqi
NP_001188320.1, NM_001201391.1
NP_001265090.1, NM_001278161.1
NP_032246.2, NM_008220.5

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100503605
101488143
15129

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:100503605
mmu:101488143
mmu:15129

UCSC genome browser

More...
UCSCi
uc009iuq.3 mouse

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14061 Genomic DNA Translation: CAA32224.1
J00413 Genomic DNA Translation: AAA37791.1
AB020013 mRNA Translation: BAA77353.1
AB020015 mRNA Translation: BAA77355.1
AK002258 mRNA Translation: BAB21971.1
AK002394 mRNA Translation: BAB22067.1
AK003096 mRNA Translation: BAB22562.1
AK003472 mRNA Translation: BAB22806.1
AK005442 mRNA Translation: BAB24036.1
AK005490 mRNA Translation: BAB24075.1
AK005496 mRNA Translation: BAB24080.1
AK010873 mRNA Translation: BAB27237.1
AK010902 mRNA Translation: BAB27255.1
AK010980 mRNA Translation: BAB27302.1
AK010981 mRNA Translation: BAB27303.1
AK010991 mRNA Translation: BAB27310.1
AK010993 mRNA Translation: BAB27312.1
AK011006 mRNA Translation: BAB27325.1
AK011013 mRNA Translation: BAB27331.1
AK011016 mRNA Translation: BAB27334.1
AK011027 mRNA Translation: BAB27343.1
AK011033 mRNA Translation: BAB27347.1
AK011050 mRNA Translation: BAB27360.1
AK011052 mRNA Translation: BAB27361.1
AK011053 mRNA Translation: BAB27362.1
AK011057 mRNA Translation: BAB27365.1
AK011067 mRNA Translation: BAB27374.1
AK011069 mRNA Translation: BAB27376.1
AK011075 mRNA Translation: BAB27380.1
AK011077 mRNA Translation: BAB27382.1
AK011083 mRNA Translation: BAB27387.1
AK011102 mRNA Translation: BAB27399.1
AK012551 mRNA Translation: BAB28311.1
AK014364 mRNA Translation: BAB29299.1
AK027903 mRNA Translation: BAC25655.1
AK027904 mRNA Translation: BAC25656.1
AK028067 mRNA Translation: BAC25734.1
AK088149 mRNA Translation: BAC40173.1
AK133714 mRNA Translation: BAE21794.1
AK147001 mRNA Translation: BAE27598.1
AK160629 mRNA Translation: BAE35926.1
AK161021 mRNA Translation: BAE36152.1
AK165490 mRNA Translation: BAE38217.1
AK167615 mRNA Translation: BAE39668.1
AK168412 mRNA Translation: BAE40327.1
AK168477 mRNA Translation: BAE40366.1
AK168562 mRNA Translation: BAE40435.1
AK168584 mRNA Translation: BAE40453.1
AK168819 mRNA Translation: BAE40646.1
AK168826 mRNA Translation: BAE40653.1
AK168846 mRNA Translation: BAE40669.1
M19236 mRNA Translation: AAA37788.1
M10828 Genomic DNA Translation: AAA37786.1
M10830, M10829 Genomic DNA Translation: AAA37787.1
M10688 Genomic DNA Translation: AAA37790.1
PIRiA90790 HBMS
RefSeqiNP_001188320.1, NM_001201391.1
NP_001265090.1, NM_001278161.1
NP_032246.2, NM_008220.5

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1JEBX-ray2.10B/D2-147[»]
3HRWX-ray2.80B/D2-147[»]
SMRiP02088
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi1639840, 1 interactor
200219, 5 interactors
3405151, 1 interactor
ComplexPortaliCPX-2922 Hemoglobin HbA complex, variant HBB1
IntActiP02088, 11 interactors
MINTiP02088
STRINGi10090.ENSMUSP00000095794

PTM databases

CarbonylDBiP02088
iPTMnetiP02088
PhosphoSitePlusiP02088
SwissPalmiP02088

2D gel databases

REPRODUCTION-2DPAGEiIPI00553333
P02088
SWISS-2DPAGEiP02088

Proteomic databases

jPOSTiP02088
MaxQBiP02088
PaxDbiP02088
PeptideAtlasiP02088
PRIDEiP02088

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
15129

Genome annotation databases

GeneIDi100503605
101488143
15129
KEGGimmu:100503605
mmu:101488143
mmu:15129
UCSCiuc009iuq.3 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
100503605
101488143
15129
MGIiMGI:96021 Hbb-b1

Phylogenomic databases

eggNOGiKOG3378 Eukaryota
COG1018 LUCA
InParanoidiP02088
KOiK13823
OrthoDBi1370439at2759
PhylomeDBiP02088

Miscellaneous databases

EvolutionaryTraceiP02088

Protein Ontology

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PROi
PR:P02088

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Family and domain databases

CDDicd08925 Hb-beta_like, 1 hit
Gene3Di1.10.490.10, 1 hit
InterProiView protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
IPR002337 Haemoglobin_b
PfamiView protein in Pfam
PF00042 Globin, 1 hit
PRINTSiPR00814 BETAHAEM
SUPFAMiSSF46458 SSF46458, 1 hit
PROSITEiView protein in PROSITE
PS01033 GLOBIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiHBB1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P02088
Secondary accession number(s): Q54AI0
, Q91V86, Q9CRZ2, Q9CXH5, Q9CY12, Q9CY54, Q9R0S6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: October 16, 2019
This is version 179 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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