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Protein

Ig gamma-2A chain C region, A allele

Gene

Ighg

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • antigen binding Source: GO_Central
  • immunoglobulin receptor binding Source: AgBase

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Ig gamma-2A chain C region, A allele
Alternative name(s):
Immunoglobulin heavy chain gamma polypeptide
Gene namesi
Name:Ighg
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:2144967 Ighg

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000153584‹1 – 330Ig gamma-2A chain C region, A alleleAdd BLAST›330

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi15Interchain (with a light chain)PROSITE-ProRule annotation1 Publication
Disulfide bondi27 ↔ 82PROSITE-ProRule annotation1 Publication
Disulfide bondi107Interchain (with a heavy chain)PROSITE-ProRule annotation1 Publication
Disulfide bondi110Interchain (with a heavy chain)PROSITE-ProRule annotation1 Publication
Disulfide bondi112Interchain (with a heavy chain)PROSITE-ProRule annotation1 Publication
Disulfide bondi144 ↔ 204PROSITE-ProRule annotation1 Publication
Glycosylationi180N-linked (GlcNAc...) asparagine1 Publication1
Disulfide bondi250 ↔ 308PROSITE-ProRule annotation1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MaxQBiP01863
PeptideAtlasiP01863
PRIDEiP01863

PTM databases

iPTMnetiP01863

Interactioni

GO - Molecular functioni

Structurei

Secondary structure

1330
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP01863
SMRiP01863
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01863

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 98Ig-like 1Add BLAST93
Domaini121 – 220Ig-like 2Add BLAST100
Domaini229 – 325Ig-like 3Add BLAST97

Keywords - Domaini

Immunoglobulin C region, Immunoglobulin domain, Repeat

Phylogenomic databases

HOVERGENiHBG005814
InParanoidiP01863

Family and domain databases

Gene3Di2.60.40.10, 3 hits
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003006 Ig/MHC_CS
IPR003597 Ig_C1-set
PfamiView protein in Pfam
PF07654 C1-set, 3 hits
SMARTiView protein in SMART
SM00407 IGc1, 3 hits
SUPFAMiSSF48726 SSF48726, 3 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 3 hits
PS00290 IG_MHC, 1 hit

Sequencei

Sequence statusi: Complete.

P01863-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
AKTTAPSVYP LAPVCGDTTG SSVTLGCLVK GYFPEPVTLT WNSGSLSSGV
60 70 80 90 100
HTFPAVLQSD LYTLSSSVTV TSSTWPSQSI TCNVAHPASS TKVDKKIEPR
110 120 130 140 150
GPTIKPCPPC KCPAPNLLGG PSVFIFPPKI KDVLMISLSP IVTCVVVDVS
160 170 180 190 200
EDDPDVQISW FVNNVEVHTA QTQTHREDYN STLRVVSALP IQHQDWMSGK
210 220 230 240 250
EFKCKVNNKD LPAPIERTIS KPKGSVRAPQ VYVLPPPEEE MTKKQVTLTC
260 270 280 290 300
MVTDFMPEDI YVEWTNNGKT ELNYKNTEPV LDSDGSYFMY SKLRVEKKNW
310 320 330
VERNSYSCSV VHEGLHNHHT TKSFSRTPGK
Length:330
Mass (Da):36,389
Last modified:July 21, 1986 - v1
Checksum:iB84361C5445A6864
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00798 mRNA Translation: CAA24178.1
PIRiA02152 G2MSA
UniGeneiMm.342177
Mm.436014

Similar proteinsi

Entry informationi

Entry nameiGCAA_MOUSE
AccessioniPrimary (citable) accession number: P01863
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: December 20, 2017
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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