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UniProtKB - P01836 (KACA_RAT)
Protein
Ig kappa chain C region, A allele
Gene
N/A
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- antigen binding Source: GO_Central
- immunoglobulin receptor binding Source: GO_Central
GO - Biological processi
- adaptive immune response Source: RGD
- B cell differentiation Source: RGD
- B cell receptor signaling pathway Source: GO_Central
- complement activation, classical pathway Source: GO_Central
- defense response to bacterium Source: GO_Central
- innate immune response Source: GO_Central
- phagocytosis, engulfment Source: GO_Central
- phagocytosis, recognition Source: GO_Central
- positive regulation of B cell activation Source: GO_Central
Names & Taxonomyi
Protein namesi | Recommended name: Ig kappa chain C region, A allele |
Organismi | Rattus norvegicus (Rat) |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1562743, LOC500183 |
Subcellular locationi
Extracellular region or secreted
- immunoglobulin complex, circulating Source: GO_Central
Plasma Membrane
- external side of plasma membrane Source: GO_Central
Other locations
- IgG immunoglobulin complex Source: RGD
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000153604 | ‹1 – 106 | Ig kappa chain C region, A alleleAdd BLAST | ›106 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 26 ↔ 86 | PROSITE-ProRule annotation | ||
Disulfide bondi | 106 | Interchain (with a heavy chain)PROSITE-ProRule annotation |
Keywords - PTMi
Disulfide bondProteomic databases
PRIDEi | P01836 |
Structurei
3D structure databases
AlphaFoldDBi | P01836 |
SMRi | P01836 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P01836 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 5 – 102 | Ig-likeAdd BLAST | 98 |
Keywords - Domaini
Immunoglobulin domainPhylogenomic databases
InParanoidi | P01836 |
PhylomeDBi | P01836 |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003006, Ig/MHC_CS IPR003597, Ig_C1-set |
Pfami | View protein in Pfam PF07654, C1-set, 1 hit |
SMARTi | View protein in SMART SM00407, IGc1, 1 hit |
SUPFAMi | SSF48726, SSF48726, 1 hit |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit PS00290, IG_MHC, 1 hit |
i Sequence
Sequence statusi: Complete.
P01836-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
ADAAPTVSIF PPSMEQLTSG GATVVCFVNN FYPRDISVKW KIDGSEQRDG
60 70 80 90 100
VLDSVTDQDS KDSTYSMSST LSLTKVEYER HNLYTCEVVH KTSSSPVVKS
FNRNEC
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | 1 |
Sequence databases
PIRi | A02118, K1RTA |
Similar proteinsi
Cross-referencesi
Sequence databases
PIRi | A02118, K1RTA |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2ARJ | X-ray | 2.88 | A/L | 1-103 | [»] | |
3B9K | X-ray | 2.70 | C/L | 1-106 | [»] | |
AlphaFoldDBi | P01836 | |||||
SMRi | P01836 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Proteomic databases
PRIDEi | P01836 |
Organism-specific databases
RGDi | 1562743, LOC500183 |
Phylogenomic databases
InParanoidi | P01836 |
PhylomeDBi | P01836 |
Miscellaneous databases
EvolutionaryTracei | P01836 |
PROi | PR:P01836 |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003006, Ig/MHC_CS IPR003597, Ig_C1-set |
Pfami | View protein in Pfam PF07654, C1-set, 1 hit |
SMARTi | View protein in SMART SM00407, IGc1, 1 hit |
SUPFAMi | SSF48726, SSF48726, 1 hit |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit PS00290, IG_MHC, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | KACA_RAT | |
Accessioni | P01836Primary (citable) accession number: P01836 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 21, 1986 |
Last sequence update: | July 21, 1986 | |
Last modified: | May 25, 2022 | |
This is version 91 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references