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UniProtKB - P01811 (HVM41_MOUSE)
Protein
Ig heavy chain V region UPC10
Gene
N/A
Organism
Mus musculus (Mouse)
Status
Functioni
Miscellaneous
This chain was isolated from an Ig gamma-2a myeloma protein binding 2,6-levan.
GO - Molecular functioni
- antigen binding Source: GO_Central
- immunoglobulin receptor binding Source: GO_Central
GO - Biological processi
- B cell receptor signaling pathway Source: GO_Central
- complement activation, classical pathway Source: GO_Central
- defense response to bacterium Source: GO_Central
- innate immune response Source: GO_Central
- phagocytosis, engulfment Source: GO_Central
- phagocytosis, recognition Source: GO_Central
- positive regulation of B cell activation Source: GO_Central
Keywordsi
Biological process | Adaptive immunity, Immunity |
Names & Taxonomyi
Protein namesi | Recommended name: Ig heavy chain V region UPC10 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Subcellular locationi
Extracellular region or secreted
- immunoglobulin complex, circulating Source: GO_Central
Plasma Membrane
- external side of plasma membrane Source: GO_Central
Keywords - Cellular componenti
ImmunoglobulinPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000059894 | 1 – ›117 | Ig heavy chain V region UPC10Add BLAST | ›117 |
Proteomic databases
MaxQBi | P01811 |
PRIDEi | P01811 |
Interactioni
GO - Molecular functioni
- immunoglobulin receptor binding Source: GO_Central
Miscellaneous databases
RNActi | P01811, protein |
Structurei
3D structure databases
SMRi | P01811 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P01811 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 116 | Ig-likeAdd BLAST | 116 |
Phylogenomic databases
OMAi | MGLEWIG |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR013106, Ig_V-set |
Pfami | View protein in Pfam PF07686, V-set, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 1 hit SM00406, IGv, 1 hit |
SUPFAMi | SSF48726, SSF48726, 1 hit |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit |
i Sequence
Sequence statusi: Complete.
P01811-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
EVKLLESGGG LVQPGGSLKL SCAASGFDFS GYWMSWVRQA PGKGLEWIGE
60 70 80 90 100
INPDSSTINY TPFLKDKFII SRDNAKNTLF LQMSKVRSED TALYFCARNW
110
DVGFDYWGQV TTLTVSS
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 117 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M36631 mRNA Translation: AAA38078.1 |
PIRi | A02081, G2MSU1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M36631 mRNA Translation: AAA38078.1 |
PIRi | A02081, G2MSU1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1UZ6 | X-ray | 2.05 | F/H/P/W | 1-117 | [»] | |
1UZ8 | X-ray | 1.80 | B/H | 1-117 | [»] | |
SMRi | P01811 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Proteomic databases
MaxQBi | P01811 |
PRIDEi | P01811 |
Phylogenomic databases
OMAi | MGLEWIG |
Miscellaneous databases
EvolutionaryTracei | P01811 |
RNActi | P01811, protein |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR013106, Ig_V-set |
Pfami | View protein in Pfam PF07686, V-set, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 1 hit SM00406, IGv, 1 hit |
SUPFAMi | SSF48726, SSF48726, 1 hit |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | HVM41_MOUSE | |
Accessioni | P01811Primary (citable) accession number: P01811 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 21, 1986 |
Last sequence update: | July 21, 1986 | |
Last modified: | February 23, 2022 | |
This is version 86 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references