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Protein

Ig kappa chain V-V region L7

Gene

Gm10881

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

There appears to be two possible splice junctions at the 3' end of the intron. The alternate would code for a protein lacking residues 17-19.

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Ig kappa chain V-V region L7
Gene namesi
Name:Gm10881
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:3642817 Gm10881

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Add BLAST20
ChainiPRO_000001519621 – ›115Ig kappa chain V-V region L7Add BLAST›95

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi43 ↔ 108PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

MaxQBiP01642
PeptideAtlasiP01642
PRIDEiP01642

Expressioni

Gene expression databases

BgeeiENSMUSG00000076563
ExpressionAtlasiP01642 baseline and differential

Structurei

Secondary structure

1115
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi24 – 27Combined sources4
Beta strandi29 – 33Combined sources5
Beta strandi39 – 47Combined sources9
Beta strandi53 – 58Combined sources6
Beta strandi65 – 69Combined sources5
Turni70 – 72Combined sources3
Beta strandi82 – 87Combined sources6
Beta strandi90 – 97Combined sources8
Helixi100 – 102Combined sources3
Beta strandi104 – 110Combined sources7
Beta strandi112 – 115Combined sources4

3D structure databases

ProteinModelPortaliP01642
SMRiP01642
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP01642

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 43Framework-1Add BLAST23
Regioni44 – 54Complementarity-determining-1Add BLAST11
Regioni55 – 69Framework-2Add BLAST15
Regioni70 – 76Complementarity-determining-27
Regioni77 – 108Framework-3Add BLAST32
Regioni109 – ›115Complementarity-determining-3›7

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region, Signal

Phylogenomic databases

GeneTreeiENSGT00920000149150
HOGENOMiHOG000059537
HOVERGENiHBG018013
InParanoidiP01642
OMAiLWVPASK

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR013106 Ig_V-set
PfamiView protein in Pfam
PF07686 V-set, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00408 IGc2, 1 hit
SM00406 IGv, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

P01642-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSTPQFLVF LLFWIPASRG DILLTQSPAI LSVSPGERVS FSCRASQSIG
60 70 80 90 100
TSIHWYQQRT NGSPRLLIKY ASESISGIPS RFSGSGSGTD FTLSINSVES
110
EDIADYYCQQ SNSWP
Length:115
Mass (Da):12,615
Last modified:July 21, 1986 - v1
Checksum:iC17BEC758C577E00
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1151

Sequence databases

PIRiA01925 KVMSL7

Genome annotation databases

EnsembliENSMUST00000103364; ENSMUSP00000100165; ENSMUSG00000076563

Similar proteinsi

Entry informationi

Entry nameiKV5A9_MOUSE
AccessioniPrimary (citable) accession number: P01642
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: June 20, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

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