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Protein

PDGF-related-transforming protein sis

Gene

V-SIS

Organism
Woolly monkey sarcoma virus (WMSV) (Smian sarcoma-associated virus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionGrowth factor

Names & Taxonomyi

Protein namesi
Recommended name:
PDGF-related-transforming protein sis
Alternative name(s):
p28sis
Gene namesi
Name:V-SIS
OrganismiWoolly monkey sarcoma virus (WMSV) (Smian sarcoma-associated virus)
Taxonomic identifieri11970 [NCBI]
Taxonomic lineageiVirusesOrterviralesRetroviridaeOrthoretrovirinaeGammaretrovirus
Virus hostiLagothrix (woolly monkeys) [TaxID: 9518]
Proteomesi
  • UP000203831 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Keywords - Diseasei

Oncogene

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001623601 – 226PDGF-related-transforming protein sisAdd BLAST226

Proteomic databases

PRIDEiP01128

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliP01128
SMRiP01128
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PDGF/VEGF growth factor family.Curated

Phylogenomic databases

KOiK17386

Family and domain databases

CDDicd00135 PDGF, 1 hit
Gene3Di2.10.90.10, 1 hit
InterProiView protein in InterPro
IPR029034 Cystine-knot_cytokine
IPR023581 PD_growth_factor_CS
IPR000072 PDGF/VEGF_dom
IPR006782 PDGF_N
IPR015583 PDGF_suB
PANTHERiPTHR11633:SF2 PTHR11633:SF2, 1 hit
PfamiView protein in Pfam
PF00341 PDGF, 1 hit
PF04692 PDGF_N, 1 hit
SMARTiView protein in SMART
SM00141 PDGF, 1 hit
SUPFAMiSSF57501 SSF57501, 1 hit
PROSITEiView protein in PROSITE
PS00249 PDGF_1, 1 hit
PS50278 PDGF_2, 1 hit

Sequencei

Sequence statusi: Complete.

P01128-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTLTWQGDPI PEELYKMLSG HSIRSFDDLQ RLLQGDSGKE DGAELDLNMT
60 70 80 90 100
RSHSGGELES LARGKRSLGS LSVAEPAMIA ECKTRTEVFE ISRRLIDRTN
110 120 130 140 150
ANFLVWPPCV EVQRCSGCCN NRNVQCRPTQ VQLRPVQVRK IEIVRKKPIF
160 170 180 190 200
KKATVTLEDH LACKCEIVAA ARAVTRSPGT SQEQRAKTTQ SRVTIRTVRV
210 220
RRPPKGKHRK CKHTHDKTAL KETLGA
Length:226
Mass (Da):25,411
Last modified:July 21, 1986 - v1
Checksum:iA16813ABB95B90C5
GO

Sequence cautioni

The sequence CAA24516 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V01201 Genomic DNA Translation: CAA24516.1 Different initiation.
PIRiA01381 TVMVSS
RefSeqiYP_001165471.2, NC_009424.4
YP_003580185.1, NC_009424.4

Genome annotation databases

GeneIDi5176147
KEGGivg:5176147

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V01201 Genomic DNA Translation: CAA24516.1 Different initiation.
PIRiA01381 TVMVSS
RefSeqiYP_001165471.2, NC_009424.4
YP_003580185.1, NC_009424.4

3D structure databases

ProteinModelPortaliP01128
SMRiP01128
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP01128

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5176147
KEGGivg:5176147

Phylogenomic databases

KOiK17386

Family and domain databases

CDDicd00135 PDGF, 1 hit
Gene3Di2.10.90.10, 1 hit
InterProiView protein in InterPro
IPR029034 Cystine-knot_cytokine
IPR023581 PD_growth_factor_CS
IPR000072 PDGF/VEGF_dom
IPR006782 PDGF_N
IPR015583 PDGF_suB
PANTHERiPTHR11633:SF2 PTHR11633:SF2, 1 hit
PfamiView protein in Pfam
PF00341 PDGF, 1 hit
PF04692 PDGF_N, 1 hit
SMARTiView protein in SMART
SM00141 PDGF, 1 hit
SUPFAMiSSF57501 SSF57501, 1 hit
PROSITEiView protein in PROSITE
PS00249 PDGF_1, 1 hit
PS50278 PDGF_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTSIS_WMSV
AccessioniPrimary (citable) accession number: P01128
Secondary accession number(s): O41283
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: June 20, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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