UniProtKB - P01100 (FOS_HUMAN)
Proto-oncogene c-Fos
FOS
Functioni
GO - Molecular functioni
- chromatin binding Source: Ensembl
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: Ensembl
- DNA-binding transcription factor activity Source: BHF-UCL
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: NTNU_SB
- protein-containing complex binding Source: Ensembl
- RNA polymerase II activating transcription factor binding Source: CAFA
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- RNA polymerase II core promoter sequence-specific DNA binding Source: CAFA
- R-SMAD binding Source: BHF-UCL
- sequence-specific double-stranded DNA binding Source: ARUK-UCL
- transcription factor binding Source: ParkinsonsUK-UCL
- transcription regulatory region sequence-specific DNA binding Source: BHF-UCL
GO - Biological processi
- aging Source: Ensembl
- cellular response to cadmium ion Source: CAFA
- cellular response to calcium ion Source: Ensembl
- cellular response to extracellular stimulus Source: Ensembl
- cellular response to hormone stimulus Source: Ensembl
- cellular response to reactive oxygen species Source: BHF-UCL
- conditioned taste aversion Source: Ensembl
- cytokine-mediated signaling pathway Source: Reactome
- DNA methylation Source: ProtInc
- Fc-epsilon receptor signaling pathway Source: Reactome
- female pregnancy Source: Ensembl
- inflammatory response Source: ProtInc
- nervous system development Source: Ensembl
- positive regulation of neuron death Source: ARUK-UCL
- positive regulation of osteoclast differentiation Source: Ensembl
- positive regulation of pri-miRNA transcription by RNA polymerase II Source: BHF-UCL
- positive regulation of transcription, DNA-templated Source: BHF-UCL
- positive regulation of transcription by RNA polymerase II Source: CAFA
- regulation of DNA-binding transcription factor activity Source: Reactome
- regulation of transcription by RNA polymerase II Source: GO_Central
- response to cAMP Source: Ensembl
- response to cold Source: Ensembl
- response to corticosterone Source: Ensembl
- response to drug Source: Ensembl
- response to gravity Source: Ensembl
- response to immobilization stress Source: Ensembl
- response to light stimulus Source: Ensembl
- response to lipopolysaccharide Source: Ensembl
- response to muscle stretch Source: Ensembl
- response to progesterone Source: Ensembl
- response to toxic substance Source: Ensembl
- skeletal muscle cell differentiation Source: Ensembl
- sleep Source: Ensembl
- SMAD protein signal transduction Source: BHF-UCL
- transcription by RNA polymerase II Source: ProtInc
- transforming growth factor beta receptor signaling pathway Source: BHF-UCL
Keywordsi
Molecular function | DNA-binding |
Enzyme and pathway databases
PathwayCommonsi | P01100 |
Reactomei | R-HSA-2559580, Oxidative Stress Induced Senescence R-HSA-2559582, Senescence-Associated Secretory Phenotype (SASP) R-HSA-2871796, FCERI mediated MAPK activation R-HSA-450341, Activation of the AP-1 family of transcription factors R-HSA-6785807, Interleukin-4 and Interleukin-13 signaling R-HSA-6796648, TP53 Regulates Transcription of DNA Repair Genes R-HSA-9018519, Estrogen-dependent gene expression R-HSA-9031628, NGF-stimulated transcription R-HSA-9634638, Estrogen-dependent nuclear events downstream of ESR-membrane signaling |
SignaLinki | P01100 |
SIGNORi | P01100 |
Names & Taxonomyi
Protein namesi | Recommended name: Proto-oncogene c-FosAlternative name(s): Cellular oncogene fos G0/G1 switch regulatory protein 7 |
Gene namesi | Name:FOS Synonyms:G0S7 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000170345.9 |
HGNCi | HGNC:3796, FOS |
MIMi | 164810, gene |
neXtProti | NX_P01100 |
Subcellular locationi
Nucleus
Endoplasmic reticulum
Cytosol
Note: In quiescent cells, present in very small amounts in the cytosol. Following induction of cell growth, first localizes to the endoplasmic reticulum and only later to the nucleus. Localization at the endoplasmic reticulum requires dephosphorylation at Tyr-10 and Tyr-30.
Cytosol
- cytosol Source: UniProtKB-SubCell
Endoplasmic reticulum
- endoplasmic reticulum Source: UniProtKB-SubCell
Nucleus
- nuclear chromatin Source: NTNU_SB
- nucleoplasm Source: HPA
- nucleus Source: BHF-UCL
Other locations
- membrane Source: Ensembl
- neuron projection Source: Ensembl
- protein-DNA complex Source: CAFA
- transcription factor AP-1 complex Source: CAFA
Keywords - Cellular componenti
Cytoplasm, Endoplasmic reticulum, NucleusPathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 10 | Y → E: Loss of activation of phospholipid synthesis; when associated with E-30. 2 Publications | 1 | |
Mutagenesisi | 10 | Y → F: Overall loss of Tyr-phosphorylation, including that of Y-30 phosphorylation. Localizes to the endoplasmic reticulum in quiescent cells. Activates phospholipid synthesis in growing cells. 2 Publications | 1 | |
Mutagenesisi | 30 | Y → E: Loss of activation of phospholipid synthesis; when associated with E-10. 2 Publications | 1 | |
Mutagenesisi | 30 | Y → F: Overall loss of Tyr-phosphorylation, including that of Y-10 phosphorylation. Localizes to the endoplasmic reticulum in quiescent cells. Activates phospholipid synthesis in growing cells. 2 Publications | 1 | |
Mutagenesisi | 106 | Y → F: No effect on Tyr-phosphorylation. Loss of endoplasmic reticulum localization in quiescent cells. 1 Publication | 1 | |
Mutagenesisi | 128 | K → R: No change in sumoylation. 1 Publication | 1 | |
Mutagenesisi | 192 | K → R: No change in sumoylation. 1 Publication | 1 | |
Mutagenesisi | 232 | T → D: Decreased sumoylation levels. | 1 | |
Mutagenesisi | 265 | K → R: Abolishes sumoylation. No change in nuclear location nor on protein stability. Increased AP1 transactivation activity when heterodimerized with cJUN. 1 Publication | 1 | |
Mutagenesisi | 325 | T → D: No change in sumoylation levels. 1 Publication | 1 | |
Mutagenesisi | 331 | T → D: No change in sumoylation levels. 1 Publication | 1 | |
Mutagenesisi | 337 | Y → F: No effect on Tyr-phosphorylation. Loss of endoplasmic reticulum localization in quiescent cells. 1 Publication | 1 | |
Mutagenesisi | 362 | S → A: Loss of protein stability. Reduced MOS/MAPK-mediated transforming ability; when associated with A-374. 2 Publications | 1 | |
Mutagenesisi | 362 | S → D: Increased protein stability. Increased MOS/MAPK-mediated transforming ability and no change in sumoylation levels; when associated with D-374. 2 Publications | 1 | |
Mutagenesisi | 374 | S → A: No change in sumoylation levels. Loss of protein stability. Reduced MOS/MAPK-mediated transforming ability; when associated with A-362. 2 Publications | 1 | |
Mutagenesisi | 374 | S → D: Increased protein stability. Increased MOS/MAPK-mediated transforming ability and no change in sumoylation levels; when associated with D-362. 2 Publications | 1 |
Keywords - Diseasei
Proto-oncogeneOrganism-specific databases
DisGeNETi | 2353 |
MalaCardsi | FOS |
OpenTargetsi | ENSG00000170345 |
Orphaneti | 528, Berardinelli-Seip congenital lipodystrophy |
PharmGKBi | PA28212 |
Miscellaneous databases
Pharosi | P01100, Tbio |
Chemistry databases
ChEMBLi | CHEMBL2111421 |
DrugBanki | DB08813, Nadroparin DB00852, Pseudoephedrine |
Polymorphism and mutation databases
BioMutai | FOS |
DMDMi | 120470 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000076465 | 1 – 380 | Proto-oncogene c-FosAdd BLAST | 380 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 10 | Phosphotyrosine; by SRC2 Publications | 1 | |
Modified residuei | 30 | Phosphotyrosine; by SRC2 Publications | 1 | |
Cross-linki | 113 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Cross-linki | 128 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Modified residuei | 232 | PhosphothreonineBy similarity | 1 | |
Cross-linki | 265 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Modified residuei | 325 | Phosphothreonine; by MAPK1 and MAPK31 Publication | 1 | |
Modified residuei | 331 | Phosphothreonine; by MAPK1 and MAPK31 Publication | 1 | |
Modified residuei | 362 | Phosphoserine; by MAPK1, MAPK3 and RPS6KA31 Publication | 1 | |
Modified residuei | 374 | Phosphoserine; by MAPK1 and MAPK32 Publications | 1 |
Post-translational modificationi
Keywords - PTMi
Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | P01100 |
jPOSTi | P01100 |
MassIVEi | P01100 |
PaxDbi | P01100 |
PeptideAtlasi | P01100 |
PRIDEi | P01100 |
ProteomicsDBi | 1860 4848 51317 [P01100-1] |
PTM databases
GlyGeni | P01100, 1 site, 1 O-linked glycan (1 site) |
iPTMneti | P01100 |
PhosphoSitePlusi | P01100 |
Expressioni
Developmental stagei
Gene expression databases
Bgeei | ENSG00000170345, Expressed in mucosa of stomach and 250 other tissues |
ExpressionAtlasi | P01100, baseline and differential |
Genevisiblei | P01100, HS |
Organism-specific databases
HPAi | ENSG00000170345, Low tissue specificity |
Interactioni
Subunit structurei
Heterodimer; with JUN (By similarity).
Interacts with MAFB (By similarity).
Component of the SMAD3/SMAD4/JUN/FOS complex required for synergistic TGF-beta-mediated transcription at the AP1 promoter site.
Interacts with SMAD3; the interaction is weak even on TGF-beta activation.
Interacts with MAFB.
Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.
Interacts with CDS1 and PI4K2A (By similarity).
By similarityBinary interactionsi
Hide detailsP01100
GO - Molecular functioni
- RNA polymerase II activating transcription factor binding Source: CAFA
- R-SMAD binding Source: BHF-UCL
- transcription factor binding Source: ParkinsonsUK-UCL
Protein-protein interaction databases
BioGRIDi | 108636, 151 interactors |
ComplexPortali | CPX-480, AP-1 transcription factor complex FOS-JUN-NFATC2 CPX-486, AP-1 transcription factor complex FOS-JUN |
CORUMi | P01100 |
DIPi | DIP-1047N |
ELMi | P01100 |
IntActi | P01100, 147 interactors |
MINTi | P01100 |
STRINGi | 9606.ENSP00000306245 |
Chemistry databases
BindingDBi | P01100 |
Miscellaneous databases
RNActi | P01100, protein |
Structurei
Secondary structure
3D structure databases
SMRi | P01100 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P01100 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 137 – 200 | bZIPPROSITE-ProRule annotationAdd BLAST | 64 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 139 – 159 | Basic motif; required for the activation of phospholipid synthesis, but not for CDS1-bindingAdd BLAST | 21 | |
Regioni | 165 – 193 | Leucine-zipperPROSITE-ProRule annotationAdd BLAST | 29 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG1414, Eukaryota |
GeneTreei | ENSGT00940000159276 |
HOGENOMi | CLU_049742_2_0_1 |
InParanoidi | P01100 |
OMAi | FTYPEAE |
PhylomeDBi | P01100 |
TreeFami | TF326301 |
Family and domain databases
DisProti | DP00078 |
IDEALi | IID00436 |
InterProi | View protein in InterPro IPR000837, AP-1 IPR004827, bZIP IPR029816, c-Fos/v-Fos |
PANTHERi | PTHR23351, PTHR23351, 1 hit PTHR23351:SF4, PTHR23351:SF4, 1 hit |
Pfami | View protein in Pfam PF00170, bZIP_1, 1 hit |
PRINTSi | PR00042, LEUZIPPRFOS |
SMARTi | View protein in SMART SM00338, BRLZ, 1 hit |
PROSITEi | View protein in PROSITE PS50217, BZIP, 1 hit PS00036, BZIP_BASIC, 1 hit |
s (3+)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MMFSGFNADY EASSSRCSSA SPAGDSLSYY HSPADSFSSM GSPVNAQDFC
60 70 80 90 100
TDLAVSSANF IPTVTAISTS PDLQWLVQPA LVSSVAPSQT RAPHPFGVPA
110 120 130 140 150
PSAGAYSRAG VVKTMTGGRA QSIGRRGKVE QLSPEEEEKR RIRRERNKMA
160 170 180 190 200
AAKCRNRRRE LTDTLQAETD QLEDEKSALQ TEIANLLKEK EKLEFILAAH
210 220 230 240 250
RPACKIPDDL GFPEEMSVAS LDLTGGLPEV ATPESEEAFT LPLLNDPEPK
260 270 280 290 300
PSVEPVKSIS SMELKTEPFD DFLFPASSRP SGSETARSVP DMDLSGSFYA
310 320 330 340 350
ADWEPLHSGS LGMGPMATEL EPLCTPVVTC TPSCTAYTSS FVFTYPEADS
360 370 380
FPSCAAAHRK GSSSNEPSSD SLSSPTLLAL
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketG3V2V7 | G3V2V7_HUMAN | Cellular oncogene fos | FOS | 232 | Annotation score: | ||
G3V5J9 | G3V5J9_HUMAN | Cellular oncogene fos | FOS | 176 | Annotation score: | ||
G3V5N7 | G3V5N7_HUMAN | Cellular oncogene fos | FOS | 142 | Annotation score: | ||
G3V5N9 | G3V5N9_HUMAN | Cellular oncogene fos | FOS | 137 | Annotation score: | ||
G3V289 | G3V289_HUMAN | Cellular oncogene fos | FOS | 170 | Annotation score: | ||
H0YJM3 | H0YJM3_HUMAN | Proto-oncogene c-Fos | FOS | 83 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 133 – 144 | SPEEE…RRIRR → ISRRRREKENPK no nucleotide entry (PubMed:15489334).CuratedAdd BLAST | 12 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_055560 | 1 – 114 | Missing in isoform 2. 1 PublicationAdd BLAST | 114 | |
Alternative sequenceiVSP_055561 | 132 – 167 | Missing in isoform 3. 1 PublicationAdd BLAST | 36 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | V01512 Genomic DNA Translation: CAA24756.1 K00650 Genomic DNA Translation: AAA52471.1 AY212879 Genomic DNA Translation: AAO21129.1 AK097379 mRNA Translation: BAG53458.1 AK290907 mRNA Translation: BAF83596.1 AK298659 mRNA Translation: BAG60827.1 AF111167 Genomic DNA Translation: AAC98315.1 CH471061 Genomic DNA Translation: EAW81229.1 BC004490 mRNA Translation: AAH04490.1 S65138 mRNA Translation: AAB20306.1 |
CCDSi | CCDS9841.1 [P01100-1] |
PIRi | A01342, TVHUF1 E34223 |
RefSeqi | NP_005243.1, NM_005252.3 [P01100-1] |
Genome annotation databases
Ensembli | ENST00000303562; ENSP00000306245; ENSG00000170345 [P01100-1] ENST00000535987; ENSP00000442268; ENSG00000170345 [P01100-3] ENST00000555686; ENSP00000452590; ENSG00000170345 [P01100-2] |
GeneIDi | 2353 |
KEGGi | hsa:2353 |
UCSCi | uc010asi.4, human [P01100-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Web resourcesi
NIEHS-SNPs |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | V01512 Genomic DNA Translation: CAA24756.1 K00650 Genomic DNA Translation: AAA52471.1 AY212879 Genomic DNA Translation: AAO21129.1 AK097379 mRNA Translation: BAG53458.1 AK290907 mRNA Translation: BAF83596.1 AK298659 mRNA Translation: BAG60827.1 AF111167 Genomic DNA Translation: AAC98315.1 CH471061 Genomic DNA Translation: EAW81229.1 BC004490 mRNA Translation: AAH04490.1 S65138 mRNA Translation: AAB20306.1 |
CCDSi | CCDS9841.1 [P01100-1] |
PIRi | A01342, TVHUF1 E34223 |
RefSeqi | NP_005243.1, NM_005252.3 [P01100-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1A02 | X-ray | 2.70 | F | 138-193 | [»] | |
1FOS | X-ray | 3.05 | E/G | 139-200 | [»] | |
1S9K | X-ray | 3.10 | D | 140-192 | [»] | |
SMRi | P01100 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 108636, 151 interactors |
ComplexPortali | CPX-480, AP-1 transcription factor complex FOS-JUN-NFATC2 CPX-486, AP-1 transcription factor complex FOS-JUN |
CORUMi | P01100 |
DIPi | DIP-1047N |
ELMi | P01100 |
IntActi | P01100, 147 interactors |
MINTi | P01100 |
STRINGi | 9606.ENSP00000306245 |
Chemistry databases
BindingDBi | P01100 |
ChEMBLi | CHEMBL2111421 |
DrugBanki | DB08813, Nadroparin DB00852, Pseudoephedrine |
PTM databases
GlyGeni | P01100, 1 site, 1 O-linked glycan (1 site) |
iPTMneti | P01100 |
PhosphoSitePlusi | P01100 |
Polymorphism and mutation databases
BioMutai | FOS |
DMDMi | 120470 |
Proteomic databases
EPDi | P01100 |
jPOSTi | P01100 |
MassIVEi | P01100 |
PaxDbi | P01100 |
PeptideAtlasi | P01100 |
PRIDEi | P01100 |
ProteomicsDBi | 1860 4848 51317 [P01100-1] |
Protocols and materials databases
ABCDi | P01100, 10 sequenced antibodies |
Antibodypediai | 4375, 1765 antibodies |
CPTCi | P01100, 4 antibodies |
DNASUi | 2353 |
Genome annotation databases
Ensembli | ENST00000303562; ENSP00000306245; ENSG00000170345 [P01100-1] ENST00000535987; ENSP00000442268; ENSG00000170345 [P01100-3] ENST00000555686; ENSP00000452590; ENSG00000170345 [P01100-2] |
GeneIDi | 2353 |
KEGGi | hsa:2353 |
UCSCi | uc010asi.4, human [P01100-1] |
Organism-specific databases
CTDi | 2353 |
DisGeNETi | 2353 |
EuPathDBi | HostDB:ENSG00000170345.9 |
GeneCardsi | FOS |
HGNCi | HGNC:3796, FOS |
HPAi | ENSG00000170345, Low tissue specificity |
MalaCardsi | FOS |
MIMi | 164810, gene |
neXtProti | NX_P01100 |
OpenTargetsi | ENSG00000170345 |
Orphaneti | 528, Berardinelli-Seip congenital lipodystrophy |
PharmGKBi | PA28212 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1414, Eukaryota |
GeneTreei | ENSGT00940000159276 |
HOGENOMi | CLU_049742_2_0_1 |
InParanoidi | P01100 |
OMAi | FTYPEAE |
PhylomeDBi | P01100 |
TreeFami | TF326301 |
Enzyme and pathway databases
PathwayCommonsi | P01100 |
Reactomei | R-HSA-2559580, Oxidative Stress Induced Senescence R-HSA-2559582, Senescence-Associated Secretory Phenotype (SASP) R-HSA-2871796, FCERI mediated MAPK activation R-HSA-450341, Activation of the AP-1 family of transcription factors R-HSA-6785807, Interleukin-4 and Interleukin-13 signaling R-HSA-6796648, TP53 Regulates Transcription of DNA Repair Genes R-HSA-9018519, Estrogen-dependent gene expression R-HSA-9031628, NGF-stimulated transcription R-HSA-9634638, Estrogen-dependent nuclear events downstream of ESR-membrane signaling |
SignaLinki | P01100 |
SIGNORi | P01100 |
Miscellaneous databases
BioGRID-ORCSi | 2353, 6 hits in 867 CRISPR screens |
ChiTaRSi | FOS, human |
EvolutionaryTracei | P01100 |
GeneWikii | C-Fos |
GenomeRNAii | 2353 |
Pharosi | P01100, Tbio |
PROi | PR:P01100 |
RNActi | P01100, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000170345, Expressed in mucosa of stomach and 250 other tissues |
ExpressionAtlasi | P01100, baseline and differential |
Genevisiblei | P01100, HS |
Family and domain databases
DisProti | DP00078 |
IDEALi | IID00436 |
InterProi | View protein in InterPro IPR000837, AP-1 IPR004827, bZIP IPR029816, c-Fos/v-Fos |
PANTHERi | PTHR23351, PTHR23351, 1 hit PTHR23351:SF4, PTHR23351:SF4, 1 hit |
Pfami | View protein in Pfam PF00170, bZIP_1, 1 hit |
PRINTSi | PR00042, LEUZIPPRFOS |
SMARTi | View protein in SMART SM00338, BRLZ, 1 hit |
PROSITEi | View protein in PROSITE PS50217, BZIP, 1 hit PS00036, BZIP_BASIC, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | FOS_HUMAN | |
Accessioni | P01100Primary (citable) accession number: P01100 Secondary accession number(s): A8K4E2, B4DQ65, P18849 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 21, 1986 |
Last sequence update: | July 21, 1986 | |
Last modified: | December 2, 2020 | |
This is version 233 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human chromosome 14
Human chromosome 14: entries, gene names and cross-references to MIM