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UniProtKB - P01097 (ATIF_YEAST)
Protein
ATPase inhibitor, mitochondrial
Gene
INH1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Forms a one-to-one complex with ATPase to inhibit the enzyme activity completely.
Miscellaneous
Present with 981 molecules/cell in log phase SD medium.1 Publication
GO - Molecular functioni
- ATPase inhibitor activity Source: SGD
- enzyme inhibitor activity Source: SGD
GO - Biological processi
- negative regulation of ATP-dependent activity Source: SGD
Names & Taxonomyi
Protein namesi | Recommended name: ATPase inhibitor, mitochondrialCuratedAlternative name(s): ATP synthase F1 subunit epsilonBy similarity |
Gene namesi | Name:INH1 Ordered Locus Names:YDL181W ORF Names:D1305 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000002340, INH1 |
VEuPathDBi | FungiDB:YDL181W |
Subcellular locationi
Mitochondrion
Mitochondrion
- mitochondrion Source: SGD
Keywords - Cellular componenti
MitochondrionPathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 41 | K → Q or E: No loss of inhibitory activity. 1 Publication | 1 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 22 | Mitochondrion2 PublicationsAdd BLAST | 22 | |
ChainiPRO_0000002554 | 23 – 85 | ATPase inhibitor, mitochondrialAdd BLAST | 63 |
Proteomic databases
MaxQBi | P01097 |
PaxDbi | P01097 |
PRIDEi | P01097 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 31863, 100 interactors |
DIPi | DIP-2985N |
IntActi | P01097, 7 interactors |
MINTi | P01097 |
STRINGi | 4932.YDL181W |
Miscellaneous databases
RNActi | P01097, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
AlphaFoldDBi | P01097 |
SMRi | P01097 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 41 – 84 | Sequence analysisAdd BLAST | 44 |
Sequence similaritiesi
Belongs to the ATPase inhibitor family.Curated
Keywords - Domaini
Coiled coil, Transit peptidePhylogenomic databases
eggNOGi | ENOG502SCJG, Eukaryota |
GeneTreei | ENSGT00940000176616 |
HOGENOMi | CLU_145563_4_0_1 |
InParanoidi | P01097 |
OMAi | DAFTRRE |
Family and domain databases
DisProti | DP00995 |
InterProi | View protein in InterPro IPR007648, ATPase_inhibitor_mt |
Pfami | View protein in Pfam PF04568, IATP, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P01097-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLPRSALARS LQLQRGVAAR FYSEGSTGTP RGSGSEDSFV KRERATEDFF
60 70 80
VRQREKEQLR HLKEQLEKQR KKIDSLENKI DSMTK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D00443 Genomic DNA Translation: BAA00344.1 X83276 Genomic DNA Translation: CAA58265.1 Z74229 Genomic DNA Translation: CAA98755.1 AY558374 Genomic DNA Translation: AAS56700.1 BK006938 Genomic DNA Translation: DAA11681.1 |
PIRi | A35231, IWBY |
RefSeqi | NP_010100.1, NM_001180241.1 |
Genome annotation databases
EnsemblFungii | YDL181W_mRNA; YDL181W; YDL181W |
GeneIDi | 851347 |
KEGGi | sce:YDL181W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D00443 Genomic DNA Translation: BAA00344.1 X83276 Genomic DNA Translation: CAA58265.1 Z74229 Genomic DNA Translation: CAA98755.1 AY558374 Genomic DNA Translation: AAS56700.1 BK006938 Genomic DNA Translation: DAA11681.1 |
PIRi | A35231, IWBY |
RefSeqi | NP_010100.1, NM_001180241.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3ZIA | X-ray | 2.50 | J/T | 23-85 | [»] | |
AlphaFoldDBi | P01097 | |||||
SMRi | P01097 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 31863, 100 interactors |
DIPi | DIP-2985N |
IntActi | P01097, 7 interactors |
MINTi | P01097 |
STRINGi | 4932.YDL181W |
Proteomic databases
MaxQBi | P01097 |
PaxDbi | P01097 |
PRIDEi | P01097 |
Genome annotation databases
EnsemblFungii | YDL181W_mRNA; YDL181W; YDL181W |
GeneIDi | 851347 |
KEGGi | sce:YDL181W |
Organism-specific databases
SGDi | S000002340, INH1 |
VEuPathDBi | FungiDB:YDL181W |
Phylogenomic databases
eggNOGi | ENOG502SCJG, Eukaryota |
GeneTreei | ENSGT00940000176616 |
HOGENOMi | CLU_145563_4_0_1 |
InParanoidi | P01097 |
OMAi | DAFTRRE |
Miscellaneous databases
PROi | PR:P01097 |
RNActi | P01097, protein |
Family and domain databases
DisProti | DP00995 |
InterProi | View protein in InterPro IPR007648, ATPase_inhibitor_mt |
Pfami | View protein in Pfam PF04568, IATP, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ATIF_YEAST | |
Accessioni | P01097Primary (citable) accession number: P01097 Secondary accession number(s): D6VRH1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 21, 1986 |
Last sequence update: | August 1, 1990 | |
Last modified: | May 25, 2022 | |
This is version 180 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome IV
Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families