Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
We will be switching to the new UniProt website soon. Please explore and share your feedback. Take me to the new website.

UniProtKB - P00582 (DPO1_ECOLI)

Entry version 211 (23 Feb 2022)
Sequence version 1 (21 Jul 1986)
Previous versions | rss
Add a publicationFeedback
Protein

DNA polymerase I

Gene

polA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • 3'-5' exonuclease activity Source: EcoCyc
  • 5'-3' exonuclease activity Source: EcoCyc
  • DNA binding Source: EcoCyc
  • DNA-directed DNA polymerase activity Source: EcoCyc
Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, DNA-directed DNA polymerase, Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, Transferase
Biological processDNA damage, DNA repair, DNA replication

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		EcoCyc:EG10746-MONOMER

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		2.7.7.7, 2026

SABIO-RK: Biochemical Reaction Kinetics Database

More...SABIO-RKi		P00582

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA polymerase I (EC:2.7.7.7)
Short name:
POL I
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:polA
Synonyms:resA
Ordered Locus Names:b3863, JW3835
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL4298

Drug and drug target database

More...DrugBanki		DB00548, Azelaic acid
DB08432, THYMIDINE-5'-THIOPHOSPHATE

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001012391 – 928DNA polymerase IAdd BLAST928

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P00582

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P00582

PRoteomics IDEntifications database

More...PRIDEi		P00582

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...SWISS-2DPAGEi		P00582

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Single-chain monomer with multiple functions.

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		4262182, 125 interactors

Database of interacting proteins

More...DIPi		DIP-10524N

Protein interaction database and analysis system

More...IntActi		P00582, 33 interactors

STRING: functional protein association networks

More...STRINGi		511145.b3863

Chemistry databases

BindingDB database of measured binding affinities

More...BindingDBi		P00582

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1928
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P00582

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P00582

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 3235'-3' exonucleaseAdd BLAST323
Domaini324 – 5173'-5' exonucleaseAdd BLAST194

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni324 – 928Klenow fragmentAdd BLAST605
Regioni521 – 928PolymeraseAdd BLAST408

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DNA polymerase type-A family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG0258, Bacteria
COG0749, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_004675_0_1_6

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P00582

Database for complete collections of gene phylogenies

More...PhylomeDBi		P00582

Family and domain databases

Conserved Domains Database

More...CDDi		cd09898, H3TH_53EXO, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.420.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR002562, 3'-5'_exonuclease_dom
IPR020046, 5-3_exonucl_a-hlix_arch_N
IPR002421, 5-3_exonuclease
IPR036279, 5-3_exonuclease_C_sf
IPR019760, DNA-dir_DNA_pol_A_CS
IPR001098, DNA-dir_DNA_pol_A_palm_dom
IPR043502, DNA/RNA_pol_sf
IPR020045, DNA_polI_H3TH
IPR018320, DNA_polymerase_1
IPR002298, DNA_polymerase_A
IPR008918, HhH2
IPR029060, PIN-like_dom_sf
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf

The PANTHER Classification System

More...PANTHERi		PTHR10133, PTHR10133, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01367, 5_3_exonuc, 1 hit
PF02739, 5_3_exonuc_N, 1 hit
PF00476, DNA_pol_A, 1 hit
PF01612, DNA_pol_A_exo1, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00868, DNAPOLI

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00474, 35EXOc, 1 hit
SM00475, 53EXOc, 1 hit
SM00279, HhH2, 1 hit
SM00482, POLAc, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47807, SSF47807, 1 hit
SSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit
SSF88723, SSF88723, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00593, pola, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00447, DNA_POLYMERASE_A, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P00582-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVQIPQNPLI LVDGSSYLYR AYHAFPPLTN SAGEPTGAMY GVLNMLRSLI 
        60         70         80         90        100
MQYKPTHAAV VFDAKGKTFR DELFEHYKSH RPPMPDDLRA QIEPLHAMVK 
       110        120        130        140        150
AMGLPLLAVS GVEADDVIGT LAREAEKAGR PVLISTGDKD MAQLVTPNIT 
       160        170        180        190        200
LINTMTNTIL GPEEVVNKYG VPPELIIDFL ALMGDSSDNI PGVPGVGEKT 
       210        220        230        240        250
AQALLQGLGG LDTLYAEPEK IAGLSFRGAK TMAAKLEQNK EVAYLSYQLA 
       260        270        280        290        300
TIKTDVELEL TCEQLEVQQP AAEELLGLFK KYEFKRWTAD VEAGKWLQAK 
       310        320        330        340        350
GAKPAAKPQE TSVADEAPEV TATVISYDNY VTILDEETLK AWIAKLEKAP 
       360        370        380        390        400
VFAFDTETDS LDNISANLVG LSFAIEPGVA AYIPVAHDYL DAPDQISRER 
       410        420        430        440        450
ALELLKPLLE DEKALKVGQN LKYDRGILAN YGIELRGIAF DTMLESYILN 
       460        470        480        490        500
SVAGRHDMDS LAERWLKHKT ITFEEIAGKG KNQLTFNQIA LEEAGRYAAE 
       510        520        530        540        550
DADVTLQLHL KMWPDLQKHK GPLNVFENIE MPLVPVLSRI ERNGVKIDPK 
       560        570        580        590        600
VLHNHSEELT LRLAELEKKA HEIAGEEFNL SSTKQLQTIL FEKQGIKPLK 
       610        620        630        640        650
KTPGGAPSTS EEVLEELALD YPLPKVILEY RGLAKLKSTY TDKLPLMINP 
       660        670        680        690        700
KTGRVHTSYH QAVTATGRLS STDPNLQNIP VRNEEGRRIR QAFIAPEDYV 
       710        720        730        740        750
IVSADYSQIE LRIMAHLSRD KGLLTAFAEG KDIHRATAAE VFGLPLETVT 
       760        770        780        790        800
SEQRRSAKAI NFGLIYGMSA FGLARQLNIP RKEAQKYMDL YFERYPGVLE 
       810        820        830        840        850
YMERTRAQAK EQGYVETLDG RRLYLPDIKS SNGARRAAAE RAAINAPMQG 
       860        870        880        890        900
TAADIIKRAM IAVDAWLQAE QPRVRMIMQV HDELVFEVHK DDVDAVAKQI 
       910        920 
HQLMENCTRL DVPLLVEVGS GENWDQAH
Length:928
Mass (Da):103,118
Last modified:July 21, 1986 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDAAE1C448A59030C
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
V00317 Genomic DNA Translation: CAA23607.1
L19201 Genomic DNA Translation: AAB02998.1
U00096 Genomic DNA Translation: AAC76861.1
AP009048 Genomic DNA Translation: BAE77445.1
J01663 Genomic DNA Translation: AAA24402.1
J01664 Genomic DNA Translation: AAA24404.1

Protein sequence database of the Protein Information Resource

More...PIRi		A92360, DJECI

NCBI Reference Sequences

More...RefSeqi		NP_418300.1, NC_000913.3
WP_000250006.1, NZ_SSZK01000026.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAC76861; AAC76861; b3863
BAE77445; BAE77445; BAE77445

Database of genes from NCBI RefSeq genomes

More...GeneIDi		66672231
948356

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecj:JW3835
eco:b3863

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|1411691.4.peg.2851

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00317 Genomic DNA Translation: CAA23607.1
L19201 Genomic DNA Translation: AAB02998.1
U00096 Genomic DNA Translation: AAC76861.1
AP009048 Genomic DNA Translation: BAE77445.1
J01663 Genomic DNA Translation: AAA24402.1
J01664 Genomic DNA Translation: AAA24404.1
PIRiA92360, DJECI
RefSeqiNP_418300.1, NC_000913.3
WP_000250006.1, NZ_SSZK01000026.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1D8YX-ray2.08A324-928[»]
1D9DX-ray2.18A324-928[»]
1D9FX-ray3.00A324-928[»]
1DPIX-ray2.80A324-928[»]
1KFDX-ray3.90A324-928[»]
1KFSX-ray2.10A324-928[»]
1KLNX-ray3.20A324-928[»]
1KRPX-ray2.20A324-928[»]
1KSPX-ray2.30A324-928[»]
1QSLX-ray2.20A324-928[»]
2KFNX-ray2.03A324-928[»]
2KFZX-ray2.03A324-928[»]
2KZMX-ray2.60A324-928[»]
2KZZX-ray2.25A324-928[»]
SMRiP00582
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi4262182, 125 interactors
DIPiDIP-10524N
IntActiP00582, 33 interactors
STRINGi511145.b3863

Chemistry databases

BindingDBiP00582
ChEMBLiCHEMBL4298
DrugBankiDB00548, Azelaic acid
DB08432, THYMIDINE-5'-THIOPHOSPHATE

2D gel databases

SWISS-2DPAGEiP00582

Proteomic databases

jPOSTiP00582
PaxDbiP00582
PRIDEiP00582

Genome annotation databases

EnsemblBacteriaiAAC76861; AAC76861; b3863
BAE77445; BAE77445; BAE77445
GeneIDi66672231
948356
KEGGiecj:JW3835
eco:b3863
PATRICifig|1411691.4.peg.2851

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...EchoBASEi		EB0739

Phylogenomic databases

eggNOGiCOG0258, Bacteria
COG0749, Bacteria
HOGENOMiCLU_004675_0_1_6
InParanoidiP00582
PhylomeDBiP00582

Enzyme and pathway databases

BioCyciEcoCyc:EG10746-MONOMER
BRENDAi2.7.7.7, 2026
SABIO-RKiP00582

Miscellaneous databases

EvolutionaryTraceiP00582

Protein Ontology

More...PROi		PR:P00582

Family and domain databases

CDDicd09898, H3TH_53EXO, 1 hit
Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR002562, 3'-5'_exonuclease_dom
IPR020046, 5-3_exonucl_a-hlix_arch_N
IPR002421, 5-3_exonuclease
IPR036279, 5-3_exonuclease_C_sf
IPR019760, DNA-dir_DNA_pol_A_CS
IPR001098, DNA-dir_DNA_pol_A_palm_dom
IPR043502, DNA/RNA_pol_sf
IPR020045, DNA_polI_H3TH
IPR018320, DNA_polymerase_1
IPR002298, DNA_polymerase_A
IPR008918, HhH2
IPR029060, PIN-like_dom_sf
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf
PANTHERiPTHR10133, PTHR10133, 1 hit
PfamiView protein in Pfam
PF01367, 5_3_exonuc, 1 hit
PF02739, 5_3_exonuc_N, 1 hit
PF00476, DNA_pol_A, 1 hit
PF01612, DNA_pol_A_exo1, 1 hit
PRINTSiPR00868, DNAPOLI
SMARTiView protein in SMART
SM00474, 35EXOc, 1 hit
SM00475, 53EXOc, 1 hit
SM00279, HhH2, 1 hit
SM00482, POLAc, 1 hit
SUPFAMiSSF47807, SSF47807, 1 hit
SSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit
SSF88723, SSF88723, 1 hit
TIGRFAMsiTIGR00593, pola, 1 hit
PROSITEiView protein in PROSITE
PS00447, DNA_POLYMERASE_A, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDPO1_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P00582
Secondary accession number(s): Q2M8G1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: February 23, 2022
This is version 211 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again