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Protein

Cytochrome c peroxidase, mitochondrial

Gene

CCP1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

Miscellaneous

Present with 6730 molecules/cell in log phase SD medium.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

heme bNote: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei115Transition state stabilizer1
<p>This subsection of the ‘Function’ section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei119Proton acceptor1
<p>This subsection of the ‘Function’ section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi242Iron (heme axial ligand)1
Active sitei258Tryptophan radical intermediate1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • cytochrome-c peroxidase activity Source: SGD
  • heme binding Source: InterPro
  • metal ion binding Source: UniProtKB-KW
  • peroxidase activity Source: GO_Central

GO - Biological processi

  • cellular response to oxidative stress Source: SGD
  • hydrogen peroxide catabolic process Source: GO_Central
  • response to reactive oxygen species Source: GO_Central

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductase, Peroxidase
Biological processHydrogen peroxide
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
YEAST:YKR066C-MONOMER

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
1.11.1.5 984

SABIO-RK: Biochemical Reaction Kinetics Database

More...
SABIO-RKi
P00431

Protein family/group databases

PeroxiBase, a peroxidase database

More...
PeroxiBasei
2361 SceCcP01

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cytochrome c peroxidase, mitochondrial (EC:1.11.1.5)
Short name:
CCP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCP1
Synonyms:CCP, CPO
Ordered Locus Names:YKR066C
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XI

Organism-specific databases

Saccharomyces Genome Database

More...
SGDi
S000001774 CCP1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi258W → F: Substantially diminished activity. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 67Mitochondrion1 PublicationAdd BLAST67
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000002363468 – 361Cytochrome c peroxidase, mitochondrialAdd BLAST294

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei220PhosphotyrosineCombined sources1

Keywords - PTMi

Organic radical, Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P00431

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P00431

PRoteomics IDEntifications database

More...
PRIDEi
P00431

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P00431

Miscellaneous databases

CutDB - Proteolytic event database

More...
PMAP-CutDBi
P00431

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms a one-to-one complex with cytochrome c.

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
CYC1P000444EBI-4389,EBI-5393

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
34197, 69 interactors

Database of interacting proteins

More...
DIPi
DIP-6251N

Protein interaction database and analysis system

More...
IntActi
P00431, 5 interactors

Molecular INTeraction database

More...
MINTi
P00431

STRING: functional protein association networks

More...
STRINGi
4932.YKR066C

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1361
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1A2FX-ray2.10A71-361[»]
1A2GX-ray2.10A71-361[»]
1AA4X-ray2.10A71-361[»]
1AC4X-ray2.10A71-361[»]
1AC8X-ray2.10A71-361[»]
1AEBX-ray2.10A71-361[»]
1AEDX-ray2.10A71-361[»]
1AEEX-ray2.10A71-361[»]
1AEFX-ray2.10A71-361[»]
1AEGX-ray2.10A71-361[»]
1AEHX-ray2.10A71-361[»]
1AEJX-ray2.10A71-361[»]
1AEKX-ray2.10A71-361[»]
1AEMX-ray2.10A71-361[»]
1AENX-ray2.10A71-361[»]
1AEOX-ray2.10A71-361[»]
1AEQX-ray2.10A71-361[»]
1AESX-ray2.10A71-361[»]
1AETX-ray2.10A71-361[»]
1AEUX-ray2.10A71-361[»]
1AEVX-ray2.10A71-361[»]
1BEJX-ray2.40A71-361[»]
1BEKX-ray2.20A71-361[»]
1BEMX-ray2.20A71-361[»]
1BEPX-ray2.20A71-361[»]
1BEQX-ray2.16A71-361[»]
1BESX-ray2.00A71-361[»]
1BJ9X-ray2.20A71-361[»]
1BVAX-ray1.89A71-361[»]
1CCAX-ray1.80A68-361[»]
1CCBX-ray2.10A68-361[»]
1CCCX-ray2.00A68-361[»]
1CCEX-ray2.30A71-361[»]
1CCGX-ray2.10A71-361[»]
1CCIX-ray2.40A71-361[»]
1CCJX-ray2.10A71-361[»]
1CCKX-ray2.10A71-361[»]
1CCLX-ray2.00A71-361[»]
1CCPX-ray2.20A68-361[»]
1CMPX-ray1.90A71-361[»]
1CMQX-ray2.30A71-361[»]
1CMTX-ray2.10A71-361[»]
1CMUX-ray2.10A71-361[»]
1CPDX-ray2.20A68-361[»]
1CPEX-ray2.20A68-361[»]
1CPFX-ray2.20A68-361[»]
1CPGX-ray2.20A71-361[»]
1CYFX-ray2.35A68-361[»]
1DCCX-ray2.20A68-361[»]
1DJ1X-ray1.93A71-361[»]
1DJ5X-ray1.93A71-361[»]
1DS4X-ray2.02A71-361[»]
1DSEX-ray2.00A71-361[»]
1DSGX-ray2.56A71-361[»]
1DSOX-ray2.03A71-361[»]
1DSPX-ray2.03A71-361[»]
1EBEX-ray2.20A68-361[»]
1JCIX-ray1.90A68-361[»]
1JDRX-ray1.50A68-361[»]
1KOKX-ray1.70A68-361[»]
1KRJX-ray2.00A68-361[»]
1KXMX-ray1.74A71-361[»]
1KXNX-ray1.80A71-361[»]
1MK8X-ray1.65A68-361[»]
1MKQX-ray1.64A68-361[»]
1MKRX-ray1.58A68-361[»]
1ML2X-ray1.65A68-361[»]
1RYCX-ray1.80A71-361[»]
1S6VX-ray1.88A/C68-361[»]
1S73X-ray1.53A68-361[»]
1SBMX-ray1.69A68-361[»]
1SDQX-ray1.69A68-361[»]
1SOGX-ray1.85A68-361[»]
1STQX-ray1.82A68-361[»]
1U74X-ray2.40A/C68-361[»]
1U75X-ray2.55A/C68-361[»]
1Z53X-ray1.13A68-361[»]
1ZBYX-ray1.20A68-361[»]
1ZBZX-ray1.29A68-361[»]
2ANZX-ray1.75A71-361[»]
2AQDX-ray1.35A71-361[»]
2AS1X-ray1.55A71-361[»]
2AS2X-ray1.45A71-361[»]
2AS3X-ray1.40A71-361[»]
2AS4X-ray1.30A71-361[»]
2AS6X-ray1.45A71-361[»]
2B0ZX-ray2.70A68-361[»]
2B10X-ray2.80A/C68-361[»]
2B11X-ray2.30A/C68-361[»]
2B12X-ray3.02A68-361[»]
2BCNX-ray1.70A/C68-361[»]
2CCPX-ray2.20A68-361[»]
2CEPX-ray2.20A68-361[»]
2CYPX-ray1.70A68-361[»]
2EUNX-ray1.70A71-361[»]
2EUOX-ray1.45A71-361[»]
2EUPX-ray1.40A71-361[»]
2EUQX-ray1.30A71-361[»]
2EURX-ray1.39A71-361[»]
2EUSX-ray1.55A71-361[»]
2EUTX-ray1.12A71-361[»]
2EUUX-ray1.45A71-361[»]
2GB8NMR-A68-361[»]
2IA8X-ray1.48A71-361[»]
2ICVX-ray1.60A71-361[»]
2JTINMR-A68-361[»]
2N18NMR-A68-361[»]
2PCBX-ray2.80A/C68-361[»]
2PCCX-ray2.30A/C68-361[»]
2RBTX-ray1.24X71-361[»]
2RBUX-ray1.80X71-361[»]
2RBVX-ray1.39X71-361[»]
2RBWX-ray1.50X71-361[»]
2RBXX-ray1.50X71-361[»]
2RBYX-ray1.50X71-361[»]
2RBZX-ray1.80X71-361[»]
2RC0X-ray1.50X71-361[»]
2RC1X-ray2.49X71-361[»]
2RC2X-ray1.50X71-361[»]
2V23X-ray1.80A68-361[»]
2V2EX-ray1.68A71-361[»]
2X07X-ray1.86A69-361[»]
2X08X-ray2.01A69-361[»]
2XILX-ray1.68A71-361[»]
2XJ5X-ray1.69A71-361[»]
2XJ8X-ray1.69A71-361[»]
2Y5AX-ray1.25A71-361[»]
2YCGX-ray1.81A68-361[»]
3CCPX-ray2.20A68-361[»]
3CCXX-ray2.30A71-361[»]
3E2NX-ray1.30A68-96[»]
A110-361[»]
3E2OX-ray1.06A68-361[»]
3EXBX-ray1.60A68-361[»]
3M23X-ray1.40A71-361[»]
3M25X-ray1.40A71-361[»]
3M26X-ray1.40A71-361[»]
3M27X-ray1.40A71-361[»]
3M28X-ray1.40A71-361[»]
3M29X-ray1.40A71-361[»]
3M2AX-ray1.40A71-361[»]
3M2BX-ray1.40A71-361[»]
3M2CX-ray1.40A71-361[»]
3M2DX-ray1.40A71-361[»]
3M2EX-ray1.40A71-361[»]
3M2FX-ray1.40A71-361[»]
3M2GX-ray1.40A71-361[»]
3M2HX-ray1.40A71-361[»]
3M2IX-ray1.40A71-361[»]
3R98Other2.40A69-361[»]
3R99Other2.40A69-361[»]
4A6ZX-ray1.61A68-361[»]
4A71X-ray1.61A68-361[»]
4A78X-ray2.01A68-361[»]
4A7MX-ray1.71A68-361[»]
4CCPX-ray2.20A68-361[»]
4CCXX-ray1.90A71-361[»]
4CVIOther2.10A70-361[»]
4CVJOther2.18A71-361[»]
4JB4X-ray2.39A/C68-361[»]
4NFGX-ray2.11A71-361[»]
4P4QX-ray2.01A/C68-361[»]
4XV4X-ray1.69A71-361[»]
4XV5X-ray1.65A71-361[»]
4XV6X-ray1.55A71-361[»]
4XV7X-ray1.62A71-361[»]
4XV8X-ray1.57A71-361[»]
4XVAX-ray2.66A/C/E/G69-361[»]
5CCPX-ray2.20A68-361[»]
5CIBX-ray3.01A/C68-361[»]
5CICX-ray2.10A/C68-361[»]
5CIDX-ray2.76A/C68-361[»]
5CIEX-ray2.60A/C68-361[»]
5CIFX-ray2.01A/C68-361[»]
5CIGX-ray2.06A/C68-361[»]
5CIHX-ray2.60A/C68-361[»]
5D6MX-ray1.65A71-361[»]
5EJTX-ray1.55A68-361[»]
5EJXX-ray1.50A68-361[»]
6CCPX-ray2.20A68-361[»]
7CCPX-ray2.20A68-361[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P00431

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P00431

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P00431

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000189824

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P00431

KEGG Orthology (KO)

More...
KOi
K00428

Identification of Orthologs from Complete Genome Data

More...
OMAi
SLMMLPT

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002016 Haem_peroxidase
IPR010255 Haem_peroxidase_sf
IPR002207 Peroxidase_I
IPR019794 Peroxidases_AS
IPR019793 Peroxidases_heam-ligand_BS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00141 peroxidase, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00459 ASPEROXIDASE
PR00458 PEROXIDASE

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48113 SSF48113, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00435 PEROXIDASE_1, 1 hit
PS00436 PEROXIDASE_2, 1 hit
PS50873 PEROXIDASE_4, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P00431-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTAVRLLPS LGRTAHKRSL YLFSAAAAAA AAATFAYSQS QKRSSSSPGG
60 70 80 90 100
GSNHGWNNWG KAAALASTTP LVHVASVEKG RSYEDFQKVY NAIALKLRED
110 120 130 140 150
DEYDNYIGYG PVLVRLAWHT SGTWDKHDNT GGSYGGTYRF KKEFNDPSNA
160 170 180 190 200
GLQNGFKFLE PIHKEFPWIS SGDLFSLGGV TAVQEMQGPK IPWRCGRVDT
210 220 230 240 250
PEDTTPDNGR LPDADKDADY VRTFFQRLNM NDREVVALMG AHALGKTHLK
260 270 280 290 300
NSGYEGPWGA ANNVFTNEFY LNLLNEDWKL EKNDANNEQW DSKSGYMMLP
310 320 330 340 350
TDYSLIQDPK YLSIVKEYAN DQDKFFKDFS KAFEKLLENG ITFPKDAPSP
360
FIFKTLEEQG L
Length:361
Mass (Da):40,353
Last modified:June 1, 1994 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA5D26385DA6F0A0B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti41Q → H in AAA88709 (PubMed:8196765).Curated1
Sequence conflicti62A → P in AAA88709 (PubMed:8196765).Curated1
Sequence conflicti145 – 146ND → DN AA sequence (PubMed:6257176).Curated2
Sequence conflicti231Missing AA sequence (PubMed:6257176).Curated1
Sequence conflicti273L → M in AAS56247 (PubMed:17322287).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti33A → AA in allele 2. 1
Natural varianti120T → I in allele 2. 1
Natural varianti219D → G in allele 2. 1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
J01468 Genomic DNA Translation: AAA88709.1
X62422 Genomic DNA Translation: CAA44288.1
Z28291 Genomic DNA Translation: CAA82145.1
AY557921 Genomic DNA Translation: AAS56247.1
J01321 Genomic DNA Translation: AAA88710.1
BK006944 Genomic DNA Translation: DAA09217.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S19064 OPBYC

NCBI Reference Sequences

More...
RefSeqi
NP_012992.1, NM_001179856.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YKR066C_mRNA; YKR066C_mRNA; YKR066C

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
853940

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YKR066C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J01468 Genomic DNA Translation: AAA88709.1
X62422 Genomic DNA Translation: CAA44288.1
Z28291 Genomic DNA Translation: CAA82145.1
AY557921 Genomic DNA Translation: AAS56247.1
J01321 Genomic DNA Translation: AAA88710.1
BK006944 Genomic DNA Translation: DAA09217.1
PIRiS19064 OPBYC
RefSeqiNP_012992.1, NM_001179856.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1A2FX-ray2.10A71-361[»]
1A2GX-ray2.10A71-361[»]
1AA4X-ray2.10A71-361[»]
1AC4X-ray2.10A71-361[»]
1AC8X-ray2.10A71-361[»]
1AEBX-ray2.10A71-361[»]
1AEDX-ray2.10A71-361[»]
1AEEX-ray2.10A71-361[»]
1AEFX-ray2.10A71-361[»]
1AEGX-ray2.10A71-361[»]
1AEHX-ray2.10A71-361[»]
1AEJX-ray2.10A71-361[»]
1AEKX-ray2.10A71-361[»]
1AEMX-ray2.10A71-361[»]
1AENX-ray2.10A71-361[»]
1AEOX-ray2.10A71-361[»]
1AEQX-ray2.10A71-361[»]
1AESX-ray2.10A71-361[»]
1AETX-ray2.10A71-361[»]
1AEUX-ray2.10A71-361[»]
1AEVX-ray2.10A71-361[»]
1BEJX-ray2.40A71-361[»]
1BEKX-ray2.20A71-361[»]
1BEMX-ray2.20A71-361[»]
1BEPX-ray2.20A71-361[»]
1BEQX-ray2.16A71-361[»]
1BESX-ray2.00A71-361[»]
1BJ9X-ray2.20A71-361[»]
1BVAX-ray1.89A71-361[»]
1CCAX-ray1.80A68-361[»]
1CCBX-ray2.10A68-361[»]
1CCCX-ray2.00A68-361[»]
1CCEX-ray2.30A71-361[»]
1CCGX-ray2.10A71-361[»]
1CCIX-ray2.40A71-361[»]
1CCJX-ray2.10A71-361[»]
1CCKX-ray2.10A71-361[»]
1CCLX-ray2.00A71-361[»]
1CCPX-ray2.20A68-361[»]
1CMPX-ray1.90A71-361[»]
1CMQX-ray2.30A71-361[»]
1CMTX-ray2.10A71-361[»]
1CMUX-ray2.10A71-361[»]
1CPDX-ray2.20A68-361[»]
1CPEX-ray2.20A68-361[»]
1CPFX-ray2.20A68-361[»]
1CPGX-ray2.20A71-361[»]
1CYFX-ray2.35A68-361[»]
1DCCX-ray2.20A68-361[»]
1DJ1X-ray1.93A71-361[»]
1DJ5X-ray1.93A71-361[»]
1DS4X-ray2.02A71-361[»]
1DSEX-ray2.00A71-361[»]
1DSGX-ray2.56A71-361[»]
1DSOX-ray2.03A71-361[»]
1DSPX-ray2.03A71-361[»]
1EBEX-ray2.20A68-361[»]
1JCIX-ray1.90A68-361[»]
1JDRX-ray1.50A68-361[»]
1KOKX-ray1.70A68-361[»]
1KRJX-ray2.00A68-361[»]
1KXMX-ray1.74A71-361[»]
1KXNX-ray1.80A71-361[»]
1MK8X-ray1.65A68-361[»]
1MKQX-ray1.64A68-361[»]
1MKRX-ray1.58A68-361[»]
1ML2X-ray1.65A68-361[»]
1RYCX-ray1.80A71-361[»]
1S6VX-ray1.88A/C68-361[»]
1S73X-ray1.53A68-361[»]
1SBMX-ray1.69A68-361[»]
1SDQX-ray1.69A68-361[»]
1SOGX-ray1.85A68-361[»]
1STQX-ray1.82A68-361[»]
1U74X-ray2.40A/C68-361[»]
1U75X-ray2.55A/C68-361[»]
1Z53X-ray1.13A68-361[»]
1ZBYX-ray1.20A68-361[»]
1ZBZX-ray1.29A68-361[»]
2ANZX-ray1.75A71-361[»]
2AQDX-ray1.35A71-361[»]
2AS1X-ray1.55A71-361[»]
2AS2X-ray1.45A71-361[»]
2AS3X-ray1.40A71-361[»]
2AS4X-ray1.30A71-361[»]
2AS6X-ray1.45A71-361[»]
2B0ZX-ray2.70A68-361[»]
2B10X-ray2.80A/C68-361[»]
2B11X-ray2.30A/C68-361[»]
2B12X-ray3.02A68-361[»]
2BCNX-ray1.70A/C68-361[»]
2CCPX-ray2.20A68-361[»]
2CEPX-ray2.20A68-361[»]
2CYPX-ray1.70A68-361[»]
2EUNX-ray1.70A71-361[»]
2EUOX-ray1.45A71-361[»]
2EUPX-ray1.40A71-361[»]
2EUQX-ray1.30A71-361[»]
2EURX-ray1.39A71-361[»]
2EUSX-ray1.55A71-361[»]
2EUTX-ray1.12A71-361[»]
2EUUX-ray1.45A71-361[»]
2GB8NMR-A68-361[»]
2IA8X-ray1.48A71-361[»]
2ICVX-ray1.60A71-361[»]
2JTINMR-A68-361[»]
2N18NMR-A68-361[»]
2PCBX-ray2.80A/C68-361[»]
2PCCX-ray2.30A/C68-361[»]
2RBTX-ray1.24X71-361[»]
2RBUX-ray1.80X71-361[»]
2RBVX-ray1.39X71-361[»]
2RBWX-ray1.50X71-361[»]
2RBXX-ray1.50X71-361[»]
2RBYX-ray1.50X71-361[»]
2RBZX-ray1.80X71-361[»]
2RC0X-ray1.50X71-361[»]
2RC1X-ray2.49X71-361[»]
2RC2X-ray1.50X71-361[»]
2V23X-ray1.80A68-361[»]
2V2EX-ray1.68A71-361[»]
2X07X-ray1.86A69-361[»]
2X08X-ray2.01A69-361[»]
2XILX-ray1.68A71-361[»]
2XJ5X-ray1.69A71-361[»]
2XJ8X-ray1.69A71-361[»]
2Y5AX-ray1.25A71-361[»]
2YCGX-ray1.81A68-361[»]
3CCPX-ray2.20A68-361[»]
3CCXX-ray2.30A71-361[»]
3E2NX-ray1.30A68-96[»]
A110-361[»]
3E2OX-ray1.06A68-361[»]
3EXBX-ray1.60A68-361[»]
3M23X-ray1.40A71-361[»]
3M25X-ray1.40A71-361[»]
3M26X-ray1.40A71-361[»]
3M27X-ray1.40A71-361[»]
3M28X-ray1.40A71-361[»]
3M29X-ray1.40A71-361[»]
3M2AX-ray1.40A71-361[»]
3M2BX-ray1.40A71-361[»]
3M2CX-ray1.40A71-361[»]
3M2DX-ray1.40A71-361[»]
3M2EX-ray1.40A71-361[»]
3M2FX-ray1.40A71-361[»]
3M2GX-ray1.40A71-361[»]
3M2HX-ray1.40A71-361[»]
3M2IX-ray1.40A71-361[»]
3R98Other2.40A69-361[»]
3R99Other2.40A69-361[»]
4A6ZX-ray1.61A68-361[»]
4A71X-ray1.61A68-361[»]
4A78X-ray2.01A68-361[»]
4A7MX-ray1.71A68-361[»]
4CCPX-ray2.20A68-361[»]
4CCXX-ray1.90A71-361[»]
4CVIOther2.10A70-361[»]
4CVJOther2.18A71-361[»]
4JB4X-ray2.39A/C68-361[»]
4NFGX-ray2.11A71-361[»]
4P4QX-ray2.01A/C68-361[»]
4XV4X-ray1.69A71-361[»]
4XV5X-ray1.65A71-361[»]
4XV6X-ray1.55A71-361[»]
4XV7X-ray1.62A71-361[»]
4XV8X-ray1.57A71-361[»]
4XVAX-ray2.66A/C/E/G69-361[»]
5CCPX-ray2.20A68-361[»]
5CIBX-ray3.01A/C68-361[»]
5CICX-ray2.10A/C68-361[»]
5CIDX-ray2.76A/C68-361[»]
5CIEX-ray2.60A/C68-361[»]
5CIFX-ray2.01A/C68-361[»]
5CIGX-ray2.06A/C68-361[»]
5CIHX-ray2.60A/C68-361[»]
5D6MX-ray1.65A71-361[»]
5EJTX-ray1.55A68-361[»]
5EJXX-ray1.50A68-361[»]
6CCPX-ray2.20A68-361[»]
7CCPX-ray2.20A68-361[»]
ProteinModelPortaliP00431
SMRiP00431
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34197, 69 interactors
DIPiDIP-6251N
IntActiP00431, 5 interactors
MINTiP00431
STRINGi4932.YKR066C

Protein family/group databases

PeroxiBasei2361 SceCcP01

PTM databases

iPTMnetiP00431

Proteomic databases

MaxQBiP00431
PaxDbiP00431
PRIDEiP00431

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYKR066C_mRNA; YKR066C_mRNA; YKR066C
GeneIDi853940
KEGGisce:YKR066C

Organism-specific databases

SGDiS000001774 CCP1

Phylogenomic databases

HOGENOMiHOG000189824
InParanoidiP00431
KOiK00428
OMAiSLMMLPT

Enzyme and pathway databases

BioCyciYEAST:YKR066C-MONOMER
BRENDAi1.11.1.5 984
SABIO-RKiP00431

Miscellaneous databases

EvolutionaryTraceiP00431
PMAP-CutDBiP00431

Protein Ontology

More...
PROi
PR:P00431

Family and domain databases

InterProiView protein in InterPro
IPR002016 Haem_peroxidase
IPR010255 Haem_peroxidase_sf
IPR002207 Peroxidase_I
IPR019794 Peroxidases_AS
IPR019793 Peroxidases_heam-ligand_BS
PfamiView protein in Pfam
PF00141 peroxidase, 1 hit
PRINTSiPR00459 ASPEROXIDASE
PR00458 PEROXIDASE
SUPFAMiSSF48113 SSF48113, 1 hit
PROSITEiView protein in PROSITE
PS00435 PEROXIDASE_1, 1 hit
PS00436 PEROXIDASE_2, 1 hit
PS50873 PEROXIDASE_4, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCCPR_YEAST
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P00431
Secondary accession number(s): D6VXC7, Q6Q5M9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: June 1, 1994
Last modified: January 16, 2019
This is version 203 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XI
    Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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