UniProtKB - P00335 (RIDH_KLEAE)
Protein
Ribitol 2-dehydrogenase
Gene
rbtD
Organism
Klebsiella aerogenes (Enterobacter aerogenes)
Status
Functioni
Miscellaneous
The sequence shown is that of strain A.
Catalytic activityi
- EC:1.1.1.56
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 160 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 20 – 43 | NADBy similarityAdd BLAST | 24 |
GO - Molecular functioni
- ribitol 2-dehydrogenase activity Source: UniProtKB-EC
Keywordsi
Molecular function | Oxidoreductase |
Ligand | NAD |
Enzyme and pathway databases
BioCyci | MetaCyc:MONOMER-12237 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:rbtD |
Organismi | Klebsiella aerogenes (Enterobacter aerogenes) |
Taxonomic identifieri | 548 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Klebsiella |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000054756 | 1 – 249 | Ribitol 2-dehydrogenaseAdd BLAST | 249 |
Interactioni
Subunit structurei
Homotetramer.
Family & Domainsi
Sequence similaritiesi
Belongs to the short-chain dehydrogenases/reductases (SDR) family.Curated
Family and domain databases
InterProi | View protein in InterPro IPR036291, NAD(P)-bd_dom_sf IPR020904, Sc_DH/Rdtase_CS IPR002347, SDR_fam |
Pfami | View protein in Pfam PF00106, adh_short, 1 hit |
PRINTSi | PR00081, GDHRDH |
SUPFAMi | SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00061, ADH_SHORT, 1 hit |
i Sequence
Sequence statusi: Complete.
P00335-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKHSVSSMNT SLSGKVAAIT GAASGIGLEC ARTLLGAGAK VVLIDREGEK
60 70 80 90 100
LNKLVAELGE NAFALQVDLM QADQVDNLLQ GILQLTGRLD IFHANAGAYI
110 120 130 140 150
GGPVAEGDPD VWDRVLHLNI NAAFRCVRSV LPHLIAQKSG DIIFTAVIAG
160 170 180 190 200
VVPVIWEPVY TASKFAVQAF VHTTRRQVAQ YGVRVGAVLP GPVVTALLDD
210 220 230 240
WPKAKMDEAL ANGSLMQPIE VAESVLFMVT RSKNVTVRDI VILPNSVDL
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 146 – 147 | AV → SS in AAA25140 (PubMed:2933028).Curated | 2 | |
Sequence conflicti | 212 | N → D AA sequence (PubMed:3904726).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural varianti | 196 | A → P in strain: D. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M25606 Genomic DNA Translation: AAA25140.1 X02448 Genomic DNA Translation: CAA26292.1 |
PIRi | A94585, DEKBR S07134 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M25606 Genomic DNA Translation: AAA25140.1 X02448 Genomic DNA Translation: CAA26292.1 |
PIRi | A94585, DEKBR S07134 |
3D structure databases
SMRi | P00335 |
ModBasei | Search... |
Enzyme and pathway databases
BioCyci | MetaCyc:MONOMER-12237 |
Family and domain databases
InterProi | View protein in InterPro IPR036291, NAD(P)-bd_dom_sf IPR020904, Sc_DH/Rdtase_CS IPR002347, SDR_fam |
Pfami | View protein in Pfam PF00106, adh_short, 1 hit |
PRINTSi | PR00081, GDHRDH |
SUPFAMi | SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00061, ADH_SHORT, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RIDH_KLEAE | |
Accessioni | P00335Primary (citable) accession number: P00335 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 21, 1986 |
Last sequence update: | August 1, 1988 | |
Last modified: | December 11, 2019 | |
This is version 103 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencingDocuments
- SIMILARITY comments
Index of protein domains and families