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UniProtKB - P00282 (AZUR_PSEAE)
Protein
Azurin
Gene
azu
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Functioni
Transfers electrons from cytochrome c551 to cytochrome oxidase.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 66 | Copper1 Publication | 1 | |
Metal bindingi | 132 | Copper1 Publication | 1 | |
Metal bindingi | 137 | Copper1 Publication | 1 | |
Metal bindingi | 141 | Copper | 1 |
GO - Molecular functioni
- copper ion binding Source: PseudoCAP
- electron transfer activity Source: InterPro
- identical protein binding Source: IntAct
- transition metal ion binding Source: PseudoCAP
- zinc ion binding Source: PseudoCAP
Keywordsi
Biological process | Electron transport, Transport |
Ligand | Copper, Metal-binding |
Enzyme and pathway databases
SABIO-RKi | P00282 |
Names & Taxonomyi
Protein namesi | Recommended name: Azurin |
Gene namesi | Name:azu Ordered Locus Names:PA4922 |
Organismi | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
Taxonomic identifieri | 208964 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › |
Proteomesi |
|
Organism-specific databases
PseudoCAPi | PA4922 |
Subcellular locationi
Other locations
Other locations
- periplasmic space Source: UniProtKB-SubCell
Keywords - Cellular componenti
PeriplasmPathology & Biotechi
Chemistry databases
DrugBanki | DB06968, 1,1'-HEXANE-1,6-DIYLBIS(1H-IMIDAZOLE) DB02586, 4,7-Dimethyl-[1,10]Phenanthroline DB04085, Bis(N-maleimidomethyl)ether DB03492, lambda-bis(2,2'-bipyridine)imidazole osmium (II) DB03871, lambda-bis(2,2'-bipyridine)imidazole ruthenium (II) DB01915, S-Hydroxycysteine DB04231, Tetra(imidazole)diaquacopper (I) DB03840, Tetra(Imidazole)Diaquacopper (Ii) DB04100, Tricarbonyl(1,10-phenanthroline)rhenium(1+) DB03570, Tris-Hydroxymethyl-Methyl-Ammonium |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 20 | 2 PublicationsAdd BLAST | 20 | |
ChainiPRO_0000002863 | 21 – 148 | AzurinAdd BLAST | 128 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 23 ↔ 46 |
Keywords - PTMi
Disulfide bondProteomic databases
PaxDbi | P00282 |
Interactioni
Binary interactionsi
P00282
With | #Exp. | IntAct |
---|---|---|
itself | 2 | EBI-8599567,EBI-8599567 |
oprC [G3XD89] | 3 | EBI-8599567,EBI-26358478 |
GO - Molecular functioni
- identical protein binding Source: IntAct
Protein-protein interaction databases
DIPi | DIP-48787N |
IntActi | P00282, 6 interactors |
MINTi | P00282 |
STRINGi | 287.DR97_2273 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
AlphaFoldDBi | P00282 |
BMRBi | P00282 |
PCDDBi | P00282 |
SMRi | P00282 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P00282 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 21 – 148 | Plastocyanin-likeAdd BLAST | 128 |
Keywords - Domaini
SignalPhylogenomic databases
HOGENOMi | CLU_112845_1_0_6 |
InParanoidi | P00282 |
OMAi | MGHNFVL |
PhylomeDBi | P00282 |
Family and domain databases
CDDi | cd13922, Azurin, 1 hit |
Gene3Di | 2.60.40.420, 1 hit |
InterProi | View protein in InterPro IPR014068, Azurin IPR000923, BlueCu_1 IPR028871, BlueCu_1_BS IPR008972, Cupredoxin |
Pfami | View protein in Pfam PF00127, Copper-bind, 1 hit |
SUPFAMi | SSF49503, SSF49503, 1 hit |
TIGRFAMsi | TIGR02695, azurin, 1 hit |
PROSITEi | View protein in PROSITE PS00196, COPPER_BLUE, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P00282-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLRKLAAVSL LSLLSAPLLA AECSVDIQGN DQMQFNTNAI TVDKSCKQFT
60 70 80 90 100
VNLSHPGNLP KNVMGHNWVL STAADMQGVV TDGMASGLDK DYLKPDDSRV
110 120 130 140
IAHTKLIGSG EKDSVTFDVS KLKEGEQYMF FCTFPGHSAL MKGTLTLK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X07317 Genomic DNA Translation: CAA30279.1 M30389 Genomic DNA Translation: AAA25730.1 AE004091 Genomic DNA Translation: AAG08307.1 |
PIRi | JQ0644, AZPSCA |
RefSeqi | NP_253609.1, NC_002516.2 WP_003095591.1, NZ_QZGE01000002.1 |
Genome annotation databases
EnsemblBacteriai | AAG08307; AAG08307; PA4922 |
GeneIDi | 878046 |
KEGGi | pae:PA4922 |
PATRICi | fig|208964.12.peg.5155 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X07317 Genomic DNA Translation: CAA30279.1 M30389 Genomic DNA Translation: AAA25730.1 AE004091 Genomic DNA Translation: AAG08307.1 |
PIRi | JQ0644, AZPSCA |
RefSeqi | NP_253609.1, NC_002516.2 WP_003095591.1, NZ_QZGE01000002.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1AG0 | X-ray | 2.40 | A/B | 20-148 | [»] | |
1AZN | X-ray | 2.60 | A/B/C/D | 21-148 | [»] | |
1AZR | X-ray | 2.40 | A/B/C/D | 21-148 | [»] | |
1AZU | X-ray | 2.70 | A | 21-148 | [»] | |
1BEX | X-ray | 2.30 | A/B | 21-148 | [»] | |
1CC3 | X-ray | 1.65 | A/B | 21-148 | [»] | |
1E5Y | X-ray | 2.00 | A/B/C/D | 21-148 | [»] | |
1E5Z | X-ray | 2.00 | A/B/C/D | 21-148 | [»] | |
1E65 | X-ray | 1.85 | A/B/C/D | 21-148 | [»] | |
1E67 | X-ray | 2.14 | A/B/C/D | 21-148 | [»] | |
1ETJ | X-ray | 2.30 | A/B/C/D | 21-148 | [»] | |
1EZL | X-ray | 2.00 | A/B/C/D | 21-148 | [»] | |
1GR7 | X-ray | 1.80 | A/B/C/D | 21-148 | [»] | |
1I53 | X-ray | 1.80 | A/B | 21-148 | [»] | |
1ILS | X-ray | 2.20 | A/B/C/D | 21-148 | [»] | |
1ILU | X-ray | 2.30 | A/B/C/D/E/F/G/H/I/K/L/M | 21-148 | [»] | |
1JVL | X-ray | 2.00 | A/B | 21-148 | [»] | |
1JVO | X-ray | 2.75 | A/B/C/D/E/F/G/H/I/J/K/L | 21-148 | [»] | |
1JZE | X-ray | 1.60 | A | 21-148 | [»] | |
1JZF | X-ray | 1.50 | A | 21-148 | [»] | |
1JZG | X-ray | 1.40 | A | 21-148 | [»] | |
1JZH | X-ray | 1.70 | A | 21-148 | [»] | |
1JZI | X-ray | 1.62 | A/B | 21-148 | [»] | |
1JZJ | X-ray | 1.80 | A/B | 21-148 | [»] | |
1NZR | X-ray | 2.20 | A/B/C/D | 21-148 | [»] | |
1R1C | X-ray | 1.90 | A/B/C/D | 21-148 | [»] | |
1VLX | X-ray | 1.90 | A/B/C/D | 21-148 | [»] | |
1XB3 | X-ray | 1.50 | A/B | 21-148 | [»] | |
1XB6 | X-ray | 1.82 | A/B | 21-148 | [»] | |
1XB8 | X-ray | 2.00 | A/C | 21-148 | [»] | |
2AZU | X-ray | 1.90 | A/B/C/D | 21-148 | [»] | |
2FNW | X-ray | 1.40 | A/B | 21-148 | [»] | |
2FT6 | X-ray | 1.25 | A | 21-148 | [»] | |
2FT7 | X-ray | 1.40 | A | 21-148 | [»] | |
2FT8 | X-ray | 1.55 | A | 21-148 | [»] | |
2FTA | X-ray | 1.61 | A/B/C/D | 21-148 | [»] | |
2GHZ | X-ray | 1.60 | A/B | 21-148 | [»] | |
2GI0 | X-ray | 1.70 | A/B | 21-148 | [»] | |
2HX7 | X-ray | 1.55 | A/B | 21-148 | [»] | |
2HX8 | X-ray | 1.60 | A/B | 21-148 | [»] | |
2HX9 | X-ray | 1.70 | A/B | 21-148 | [»] | |
2HXA | X-ray | 2.21 | A/B | 21-148 | [»] | |
2I7O | X-ray | 1.50 | A | 21-148 | [»] | |
2I7S | X-ray | 1.35 | A/B/C/D | 21-148 | [»] | |
2IDF | X-ray | 2.25 | A/B | 21-148 | [»] | |
2IWE | X-ray | 2.83 | A/D/G/J | 21-148 | [»] | |
2OJ1 | X-ray | 2.30 | A/B | 21-148 | [»] | |
2TSA | X-ray | 2.20 | A/B/C/D | 21-148 | [»] | |
2TSB | X-ray | 2.30 | A/B/C/D | 21-148 | [»] | |
2XV0 | X-ray | 1.60 | A | 21-148 | [»] | |
2XV2 | X-ray | 1.60 | A | 21-148 | [»] | |
2XV3 | X-ray | 2.30 | A/B | 21-148 | [»] | |
3AZU | X-ray | 2.10 | A/B/C/D | 21-148 | [»] | |
3FPY | X-ray | 2.10 | A | 21-148 | [»] | |
3FQ1 | X-ray | 1.90 | A | 21-148 | [»] | |
3FQ2 | X-ray | 1.91 | A | 21-148 | [»] | |
3FQY | X-ray | 1.90 | A | 21-148 | [»] | |
3FS9 | X-ray | 1.05 | A | 21-148 | [»] | |
3FSA | X-ray | 0.98 | A | 21-148 | [»] | |
3FSV | X-ray | 2.30 | A | 21-148 | [»] | |
3FSW | X-ray | 2.00 | A/B/C/D | 21-148 | [»] | |
3FSZ | X-ray | 2.00 | A/B | 21-148 | [»] | |
3FT0 | X-ray | 1.80 | A/B | 21-148 | [»] | |
3IBO | X-ray | 1.45 | A/B/C/D | 21-148 | [»] | |
3IN0 | X-ray | 2.35 | A/B/C/D | 21-148 | [»] | |
3IN2 | X-ray | 2.60 | A | 21-148 | [»] | |
3JT2 | X-ray | 2.10 | A/B | 21-148 | [»] | |
3JTB | X-ray | 1.80 | A/B/C/D | 21-148 | [»] | |
3N2J | X-ray | 1.35 | A/B/C/D/E/F/G/H/I/J/K/L | 21-148 | [»] | |
3NP3 | X-ray | 2.10 | A | 21-148 | [»] | |
3NP4 | X-ray | 2.25 | A | 21-148 | [»] | |
3OQR | X-ray | 2.40 | A | 21-148 | [»] | |
3U25 | X-ray | 1.18 | A/B | 22-148 | [»] | |
3UGE | X-ray | 1.70 | A/B/C/D | 21-148 | [»] | |
4AZU | X-ray | 1.90 | A/B/C/D | 21-148 | [»] | |
4BWW | X-ray | 1.48 | A/B/C/D | 21-148 | [»] | |
4HHG | X-ray | 1.60 | A | 21-148 | [»] | |
4HHW | X-ray | 2.00 | A/B | 21-148 | [»] | |
4HIP | X-ray | 1.90 | A/B | 21-148 | [»] | |
4HZ1 | X-ray | 2.20 | A/B/C/D | 21-148 | [»] | |
4JKN | X-ray | 1.54 | A/B/C/D | 21-148 | [»] | |
4K9J | X-ray | 1.70 | A | 21-148 | [»] | |
4KO5 | X-ray | 1.79 | A/B | 21-148 | [»] | |
4KO6 | X-ray | 1.74 | A/B/C/D | 21-148 | [»] | |
4KO7 | X-ray | 2.07 | A/B/C/D | 21-148 | [»] | |
4KO9 | X-ray | 2.05 | A/B/C/D | 21-148 | [»] | |
4KOB | X-ray | 1.87 | A/B/C/D | 21-148 | [»] | |
4KOC | X-ray | 1.46 | A | 21-148 | [»] | |
4MFH | X-ray | 1.54 | A/B/C | 21-148 | [»] | |
4QKT | X-ray | 1.64 | A/B | 21-148 | [»] | |
4QLW | X-ray | 2.00 | A/B/C/D | 21-148 | [»] | |
4WKX | X-ray | 1.94 | A/B | 21-148 | [»] | |
5AZU | X-ray | 1.90 | A/B/C/D | 21-148 | [»] | |
5I26 | X-ray | 1.89 | A/B/C/D | 21-148 | [»] | |
5I28 | X-ray | 1.95 | A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P | 21-148 | [»] | |
5SYD | X-ray | 2.40 | A/B | 63-148 | [»] | |
5YT7 | X-ray | 1.66 | A/B/C/D | 21-134 | [»] | |
6GYI | X-ray | 1.60 | A/B/C/D | 21-148 | [»] | |
6IAV | X-ray | 2.00 | A/B/C/D | 22-148 | [»] | |
6MJR | X-ray | 2.01 | A/B/C/D | 22-148 | [»] | |
6MJS | X-ray | 1.85 | A/B/C/D | 22-148 | [»] | |
6MJT | X-ray | 1.89 | A/B | 22-148 | [»] | |
AlphaFoldDBi | P00282 | |||||
BMRBi | P00282 | |||||
PCDDBi | P00282 | |||||
SMRi | P00282 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
DIPi | DIP-48787N |
IntActi | P00282, 6 interactors |
MINTi | P00282 |
STRINGi | 287.DR97_2273 |
Chemistry databases
DrugBanki | DB06968, 1,1'-HEXANE-1,6-DIYLBIS(1H-IMIDAZOLE) DB02586, 4,7-Dimethyl-[1,10]Phenanthroline DB04085, Bis(N-maleimidomethyl)ether DB03492, lambda-bis(2,2'-bipyridine)imidazole osmium (II) DB03871, lambda-bis(2,2'-bipyridine)imidazole ruthenium (II) DB01915, S-Hydroxycysteine DB04231, Tetra(imidazole)diaquacopper (I) DB03840, Tetra(Imidazole)Diaquacopper (Ii) DB04100, Tricarbonyl(1,10-phenanthroline)rhenium(1+) DB03570, Tris-Hydroxymethyl-Methyl-Ammonium |
Proteomic databases
PaxDbi | P00282 |
Protocols and materials databases
DNASUi | 878046 |
Genome annotation databases
EnsemblBacteriai | AAG08307; AAG08307; PA4922 |
GeneIDi | 878046 |
KEGGi | pae:PA4922 |
PATRICi | fig|208964.12.peg.5155 |
Organism-specific databases
PseudoCAPi | PA4922 |
Phylogenomic databases
HOGENOMi | CLU_112845_1_0_6 |
InParanoidi | P00282 |
OMAi | MGHNFVL |
PhylomeDBi | P00282 |
Enzyme and pathway databases
SABIO-RKi | P00282 |
Miscellaneous databases
EvolutionaryTracei | P00282 |
Family and domain databases
CDDi | cd13922, Azurin, 1 hit |
Gene3Di | 2.60.40.420, 1 hit |
InterProi | View protein in InterPro IPR014068, Azurin IPR000923, BlueCu_1 IPR028871, BlueCu_1_BS IPR008972, Cupredoxin |
Pfami | View protein in Pfam PF00127, Copper-bind, 1 hit |
SUPFAMi | SSF49503, SSF49503, 1 hit |
TIGRFAMsi | TIGR02695, azurin, 1 hit |
PROSITEi | View protein in PROSITE PS00196, COPPER_BLUE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | AZUR_PSEAE | |
Accessioni | P00282Primary (citable) accession number: P00282 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 21, 1986 |
Last sequence update: | July 1, 1989 | |
Last modified: | May 25, 2022 | |
This is version 177 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references