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Entry version 177 (22 Apr 2020)
Sequence version 3 (23 Apr 2003)
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Protein

Cytochrome b

Gene

COB

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c (Probable). Cytochrome b is a catalytic core subunit containing 2 b-type hemes BL and BH topographically segregated in the quinone reduction (Qi) and quinol oxidation (Q0) sites on opposite sides of the membrane (PubMed:18390544).3 Publications1 Publication

Miscellaneous

Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

heme4 PublicationsNote: Binds 2 heme b groups non-covalently per subunit.4 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei16Ubiquinone1 Publication1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi82Iron 1 (heme b562 axial ligand); via tele nitrogenCombined sources4 Publications1
Metal bindingi96Iron 2 (heme b566 axial ligand); via tele nitrogenCombined sources4 Publications1
Metal bindingi183Iron 1 (heme b562 axial ligand); via tele nitrogenCombined sources4 Publications1
Metal bindingi197Iron 2 (heme b566 axial ligand); via tele nitrogenCombined sources4 Publications1
Binding sitei202UbiquinoneBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTranslocase
Biological processElectron transport, Respiratory chain, Transport
LigandHeme, Iron, Metal-binding, Ubiquinone

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
YEAST:Q0105-MONOMER

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SCE-611105 Respiratory electron transport

Protein family/group databases

Transport Classification Database

More...
TCDBi
3.D.3.3.1 the proton-translocating quinol:cytochrome c reductase (qcr) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cytochrome b (EC:7.1.1.82 Publications)
Alternative name(s):
Complex III subunit 3
Complex III subunit CYTB
Complex III subunit III
Cytochrome b-c1 complex subunit 3
Cytochrome b-c1 complex subunit CYTB
Ubiquinol-cytochrome c oxidoreductase complex cytochrome b subunit
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:COB
Synonyms:CYTB
Ordered Locus Names:Q0105
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates if the gene coding for the protein originates from the hydrogenosome, the mitochondrion, the nucleomorph, different plastids or a plasmid. The absence of this section means that the gene is located in one of the main chromosomal element(s).<p><a href='/help/encoded_on' target='_top'>More...</a></p>Encoded oniMitochondrion
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Mitochondrion

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:Q0105

Saccharomyces Genome Database

More...
SGDi
S000007270 COB

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 27Mitochondrial matrix1 Publication2 PublicationsAdd BLAST27
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei28 – 51HelicalCombined sources4 PublicationsAdd BLAST24
Topological domaini52 – 74Mitochondrial intermembrane1 Publication2 PublicationsAdd BLAST23
Transmembranei75 – 102HelicalCombined sources4 PublicationsAdd BLAST28
Topological domaini103 – 110Mitochondrial matrix1 Publication2 Publications8
Transmembranei111 – 135HelicalCombined sources4 PublicationsAdd BLAST25
Topological domaini136 – 172Mitochondrial intermembrane1 Publication2 PublicationsAdd BLAST37
Transmembranei173 – 204HelicalCombined sources4 PublicationsAdd BLAST32
Topological domaini205 – 223Mitochondrial matrix1 Publication2 PublicationsAdd BLAST19
Transmembranei224 – 246HelicalCombined sources4 PublicationsAdd BLAST23
Topological domaini247 – 287Mitochondrial intermembrane1 Publication2 PublicationsAdd BLAST41
Transmembranei288 – 308HelicalCombined sources4 PublicationsAdd BLAST21
Topological domaini309 – 319Mitochondrial matrix1 Publication2 PublicationsAdd BLAST11
Transmembranei320 – 340HelicalCombined sources4 PublicationsAdd BLAST21
Topological domaini341 – 347Mitochondrial intermembrane1 Publication2 Publications7
Transmembranei348 – 364HelicalCombined sources4 PublicationsAdd BLAST17
Topological domaini365 – 385Mitochondrial matrix1 Publication2 PublicationsAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000617691 – 385Cytochrome bAdd BLAST385

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P00163

PRoteomics IDEntifications database

More...
PRIDEi
P00163

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P00163

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 10 subunits. The complex is composed of 3 respiratory subunits cytochrome b (COB), cytochrome c1 (CYT1) and Rieske protein (RIP1), 2 core protein subunits COR1 and QCR2, and 5 low-molecular weight protein subunits QCR6, QCR7, QCR8, QCR9 and QCR10 (PubMed:10873857, PubMed:11880631, PubMed:8031140, PubMed:30598554). The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with a monomer or a dimer of cytochrome c oxidase (complex IV, CIV), resulting in 2 different assemblies (supercomplexes III2IV and III2IV2) (PubMed:10775262, PubMed:10764779, PubMed:30598556, PubMed:30598554).

7 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
34779, 37 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-567 Mitochondrial electron transport complex III

Protein interaction database and analysis system

More...
IntActi
P00163, 3 interactors

STRING: functional protein association networks

More...
STRINGi
4932.Q0105

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P00163 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1385
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P00163

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P00163

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the cytochrome b family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_031114_3_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P00163

KEGG Orthology (KO)

More...
KOi
K00412

Identification of Orthologs from Complete Genome Data

More...
OMAi
HETGSNN

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00290 cytochrome_b_C, 1 hit
cd00284 Cytochrome_b_N, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.810.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005798 Cyt_b/b6_C
IPR036150 Cyt_b/b6_C_sf
IPR005797 Cyt_b/b6_N
IPR027387 Cytb/b6-like_sf
IPR030689 Cytochrome_b
IPR016174 Di-haem_cyt_TM

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00032 Cytochrom_B_C, 1 hit
PF00033 Cytochrome_B, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF038885 COB, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF81342 SSF81342, 1 hit
SSF81648 SSF81648, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51003 CYTB_CTER, 1 hit
PS51002 CYTB_NTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P00163-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAFRKSNVYL SLVNSYIIDS PQPSSINYWW NMGSLLGLCL VIQIVTGIFM
60 70 80 90 100
AMHYSSNIEL AFSSVEHIMR DVHNGYILRY LHANGASFFF MVMFMHMAKG
110 120 130 140 150
LYYGSYRSPR VTLWNVGVII FILTIATAFL GYCCVYGQMS HWGATVITNL
160 170 180 190 200
FSAIPFVGND IVSWLWGGFS VSNPTIQRFF ALHYLVPFII AAMVIMHLMA
210 220 230 240 250
LHIHGSSNPL GITGNLDRIP MHSYFIFKDL VTVFLFMLIL ALFVFYSPNT
260 270 280 290 300
LGHPDNYIPG NPLVTPASIV PEWYLLPFYA ILRSIPDKLL GVITMFAAIL
310 320 330 340 350
VLLVLPFTDR SVVRGNTFKV LSKFFFFIFV FNFVLLGQIG ACHVEVPYVL
360 370 380
MGQIATFIYF AYFLIIVPVI STIENVLFYI GRVNK
Length:385
Mass (Da):43,656
Last modified:April 23, 2003 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1B1B1616BBC2A798
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti122I → T in CAA58861 (PubMed:7737175).Curated1
Sequence conflicti122I → T in AAA32151 (PubMed:7004642).Curated1
Sequence conflicti269I → ID in CAA24073 (PubMed:6253454).Curated1
Sequence conflicti269I → ID no nucleotide entry (PubMed:6383504).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti131G → S in mutant W7 which is respiratory deficient. 1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
V00696 Genomic DNA Translation: CAA24073.2 Sequence problems.
X84042 mRNA Translation: CAA58861.1
KP263414 Genomic DNA Translation: AIZ98890.1
J01473, J01472 Genomic DNA Translation: AAA32151.2
J01475, J01474 Genomic DNA Translation: AAA32152.2

Protein sequence database of the Protein Information Resource

More...
PIRi
A00159 CBBY
S78660

NCBI Reference Sequences

More...
RefSeqi
NP_009315.1, NC_001224.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
Q0105_mRNA; Q0105; Q0105

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
854583

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:Q0105

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00696 Genomic DNA Translation: CAA24073.2 Sequence problems.
X84042 mRNA Translation: CAA58861.1
KP263414 Genomic DNA Translation: AIZ98890.1
J01473, J01472 Genomic DNA Translation: AAA32151.2
J01475, J01474 Genomic DNA Translation: AAA32152.2
PIRiA00159 CBBY
S78660
RefSeqiNP_009315.1, NC_001224.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1EZVX-ray2.30C1-385[»]
1KB9X-ray2.30C1-385[»]
1KYOX-ray2.97C/N1-385[»]
1P84X-ray2.50C1-385[»]
2IBZX-ray2.30C1-385[»]
3CX5X-ray1.90C/N1-385[»]
3CXHX-ray2.50C/N1-385[»]
4PD4X-ray3.04C1-385[»]
6GIQelectron microscopy3.23C/N1-385[»]
6HU9electron microscopy3.35C/N1-385[»]
SMRiP00163
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi34779, 37 interactors
ComplexPortaliCPX-567 Mitochondrial electron transport complex III
IntActiP00163, 3 interactors
STRINGi4932.Q0105

Protein family/group databases

TCDBi3.D.3.3.1 the proton-translocating quinol:cytochrome c reductase (qcr) superfamily

Proteomic databases

PaxDbiP00163
PRIDEiP00163
TopDownProteomicsiP00163

Genome annotation databases

EnsemblFungiiQ0105_mRNA; Q0105; Q0105
GeneIDi854583
KEGGisce:Q0105

Organism-specific databases

EuPathDBiFungiDB:Q0105
SGDiS000007270 COB

Phylogenomic databases

HOGENOMiCLU_031114_3_0_1
InParanoidiP00163
KOiK00412
OMAiHETGSNN

Enzyme and pathway databases

BioCyciYEAST:Q0105-MONOMER
ReactomeiR-SCE-611105 Respiratory electron transport

Miscellaneous databases

EvolutionaryTraceiP00163

Protein Ontology

More...
PROi
PR:P00163
RNActiP00163 protein

Family and domain databases

CDDicd00290 cytochrome_b_C, 1 hit
cd00284 Cytochrome_b_N, 1 hit
Gene3Di1.20.810.10, 1 hit
InterProiView protein in InterPro
IPR005798 Cyt_b/b6_C
IPR036150 Cyt_b/b6_C_sf
IPR005797 Cyt_b/b6_N
IPR027387 Cytb/b6-like_sf
IPR030689 Cytochrome_b
IPR016174 Di-haem_cyt_TM
PfamiView protein in Pfam
PF00032 Cytochrom_B_C, 1 hit
PF00033 Cytochrome_B, 1 hit
PIRSFiPIRSF038885 COB, 1 hit
SUPFAMiSSF81342 SSF81342, 1 hit
SSF81648 SSF81648, 1 hit
PROSITEiView protein in PROSITE
PS51003 CYTB_CTER, 1 hit
PS51002 CYTB_NTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCYB_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P00163
Secondary accession number(s): A0A0A7NYK0
, Q35802, Q35807, Q36301, Q9ZZW9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: April 23, 2003
Last modified: April 22, 2020
This is version 177 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. SIMILARITY comments
    Index of protein domains and families
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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