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Protein
Submitted name:

LD29223p

Gene

par-6

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • apical protein localization Source: FlyBase
  • asymmetric neuroblast division Source: FlyBase
  • border follicle cell migration Source: FlyBase
  • branching involved in open tracheal system development Source: FlyBase
  • establishment of neuroblast polarity Source: FlyBase
  • establishment or maintenance of epithelial cell apical/basal polarity Source: FlyBase
  • establishment or maintenance of neuroblast polarity Source: FlyBase
  • establishment or maintenance of polarity of embryonic epithelium Source: FlyBase
  • morphogenesis of a polarized epithelium Source: FlyBase
  • negative regulation of protein kinase activity Source: FlyBase
  • positive regulation of filopodium assembly Source: FlyBase
  • positive regulation of lamellipodium assembly Source: FlyBase
  • synapse assembly Source: FlyBase
  • terminal branching, open tracheal system Source: FlyBase
  • zonula adherens assembly Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-4608870 Asymmetric localization of PCP proteins

Names & Taxonomyi

Protein namesi
Submitted name:
LD29223pImported
Submitted name:
PAR-6Imported
Submitted name:
Par-6, isoform AImported
Submitted name:
Par-6, isoform BImported
Gene namesi
Name:par-6Imported
Synonyms:Dm-Par-6Imported, Dm-Par6Imported, Dmel\CG5884Imported, DmPAR-6Imported, DmPar-6Imported, dmPar-6Imported, DmPar6Imported, Dmpar6Imported, DPar-6Imported, dPAR-6Imported, dPar-6Imported, DPar6Imported, ParImported, parImported, PAR-6Imported, Par-6Imported, PAR6Imported, Par6Imported, par6Imported
ORF Names:CG5884Imported, Dmel_CG5884Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0026192 par-6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiO97111

Expressioni

Gene expression databases

BgeeiFBgn0026192

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

DIPiDIP-17759N
IntActiO97111, 19 interactors
STRINGi7227.FBpp0074229

Structurei

3D structure databases

SMRiO97111
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 101PB1InterPro annotationAdd BLAST83
Domaini160 – 253PDZInterPro annotationAdd BLAST94

Phylogenomic databases

eggNOGiKOG3606 Eukaryota
ENOG410XRJ3 LUCA
GeneTreeiENSGT00390000005255
KOiK06093
OMAiIQFLILY
OrthoDBiEOG091G0FFH

Family and domain databases

CDDicd06403 PB1_Par6, 1 hit
InterProiView protein in InterPro
IPR034874 PAR-6_G
IPR000270 PB1_dom
IPR034868 PB1_Par6
IPR001478 PDZ
IPR036034 PDZ_sf
PANTHERiPTHR14102:SF3 PTHR14102:SF3, 1 hit
PfamiView protein in Pfam
PF00564 PB1, 1 hit
PF00595 PDZ, 1 hit
SMARTiView protein in SMART
SM00666 PB1, 1 hit
SM00228 PDZ, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS51745 PB1, 1 hit
PS50106 PDZ, 1 hit

Sequencei

Sequence statusi: Complete.

O97111-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKNKINTTS ATAASDTNLI EVKSKFDAEF RRWSFKRNEA EQSFDKFASL
60 70 80 90 100
IEQLHKLTNI QFLILYIDPR DNDLLPINND DNFGRALKTA RPLLRVIVQR
110 120 130 140 150
KDDLNEYSGF GTMKPRNLIG SILMGHTPVK TKAPSISIPH DFRQVSAIID
160 170 180 190 200
VDIVPETHRR VRLLKHGSDK PLGFYIRDGT SVRVTASGLE KQPGIFISRL
210 220 230 240 250
VPGGLAESTG LLAVNDEVIE VNGIEVAGKT LDQVTDMMVA NSSNLIITVK
260 270 280 290 300
PANQRTLTST HRGSFSRNSQ LSSGSHHTNN TNTSDEIEHD DQDDIVDLTG
310 320 330 340 350
VTLDESPTST SAGNHNHQPP LSSSPSSHHQ QAASNASTIM ASDVKDGVLH

L
Length:351
Mass (Da):38,520
Last modified:May 1, 1999 - v1
Checksum:i3097047D5348C84C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF070969 mRNA Translation: AAD15927.1
AE014298 Genomic DNA Translation: AAF48757.1
AY061369 mRNA Translation: AAL28917.1
AE014298 Genomic DNA Translation: AAN09592.1
RefSeqiNP_573238.1, NM_133010.5
NP_728094.1, NM_167575.2
UniGeneiDm.3245

Genome annotation databases

EnsemblMetazoaiFBtr0074455; FBpp0074229; FBgn0026192
FBtr0074456; FBpp0074230; FBgn0026192
GeneIDi32752
KEGGidme:Dmel_CG5884
UCSCiCG5884-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiO97111_DROME
AccessioniPrimary (citable) accession number: O97111
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: July 18, 2018
This is version 162 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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