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Protein

Small ubiquitin-related modifier

Gene

smt3

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular protein modification process Source: FlyBase
  • cellular response to transforming growth factor beta stimulus Source: FlyBase
  • central nervous system projection neuron axonogenesis Source: FlyBase
  • dendritic spine morphogenesis Source: FlyBase
  • dorsal appendage formation Source: FlyBase
  • lipid homeostasis Source: FlyBase
  • mitotic spindle organization Source: FlyBase
  • positive regulation of MAP kinase activity Source: FlyBase
  • positive regulation of MyD88-dependent toll-like receptor signaling pathway Source: FlyBase
  • positive regulation of protein localization to plasma membrane Source: FlyBase
  • positive regulation of Ras protein signal transduction Source: FlyBase
  • protein desumoylation Source: FlyBase
  • protein import into nucleus Source: FlyBase
  • protein sumoylation Source: FlyBase
  • pupariation Source: FlyBase
  • syncytial blastoderm mitotic cell cycle Source: FlyBase
  • tricarboxylic acid cycle Source: FlyBase

Keywordsi

Biological processUbl conjugation pathwayUniRule annotation

Enzyme and pathway databases

ReactomeiR-DME-196791 Vitamin D (calciferol) metabolism
R-DME-3065679 SUMO is proteolytically processed
R-DME-3108214 SUMOylation of DNA damage response and repair proteins
R-DME-3232118 SUMOylation of transcription factors
R-DME-4551638 SUMOylation of chromatin organization proteins
R-DME-4570464 SUMOylation of RNA binding proteins
R-DME-4615885 SUMOylation of DNA replication proteins
R-DME-5696395 Formation of Incision Complex in GG-NER

Names & Taxonomyi

Protein namesi
Recommended name:
Small ubiquitin-related modifierUniRule annotation
Short name:
SUMOUniRule annotation
Gene namesi
Name:smt3Imported
Synonyms:anon-EST:Posey240Imported, Dm0342Imported, Dmel\CG4494Imported, DmSmt3Imported, Dmsmt3Imported, DmSUMO-1Imported, dSmt3Imported, dsmt3Imported, l(2)04493Imported, l(2)SH0182Imported, l(2)SH2 0182Imported, SMT3Imported, Smt3Imported, SUMOImported, SumoImported, sumoImported
ORF Names:CG4494Imported, Dmel_CG4494Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0264922 smt3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotation

Expressioni

Gene expression databases

BgeeiFBgn0264922

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0078984

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2K1FNMR-A1-88[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 88Ubiquitin-likeInterPro annotationAdd BLAST78

Sequence similaritiesi

Belongs to the ubiquitin family. SUMO subfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG1769 Eukaryota
COG5227 LUCA
GeneTreeiENSGT00390000018808
KOiK12160
OMAiNDTIDVM
OrthoDBiEOG091G10ZQ

Family and domain databases

CDDicd01763 Sumo, 1 hit
InterProiView protein in InterPro
IPR022617 Rad60/SUMO-like_dom
IPR033950 Sumo
IPR029071 Ubiquitin-like_domsf
IPR000626 Ubiquitin_dom
PfamiView protein in Pfam
PF11976 Rad60-SLD, 1 hit
SMARTiView protein in SMART
SM00213 UBQ, 1 hit
SUPFAMiSSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50053 UBIQUITIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

O97102-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDEKKGGET EHINLKVLGQ DNAVVQFKIK KHTPLRKLMN AYCDRAGLSM
60 70 80 90
QVVRFRFDGQ PINENDTPTS LEMEEGDTIE VYQQQTGGAP
Length:90
Mass (Da):10,124
Last modified:May 1, 1999 - v1
Checksum:iE49DA04C24A13CA5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei90Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF053083 mRNA Translation: AAD19219.1
AF218862 mRNA Translation: AAF31702.1
AE014134 Genomic DNA Translation: AAF52470.1
AY061090 mRNA Translation: AAL28638.1
AE014134 Genomic DNA Translation: ALI30198.1
KX531939 mRNA Translation: ANY27749.1
RefSeqiNP_001303312.1, NM_001316383.1
NP_477411.1, NM_058063.4
UniGeneiDm.6873

Genome annotation databases

EnsemblMetazoaiFBtr0079356; FBpp0078984; FBgn0264922
FBtr0346716; FBpp0312327; FBgn0264922
GeneIDi33981
KEGGidme:Dmel_CG4494
UCSCiCG4494-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiO97102_DROME
AccessioniPrimary (citable) accession number: O97102
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: June 20, 2018
This is version 159 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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