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Entry version 165 (10 Feb 2021)
Sequence version 2 (10 May 2004)
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Protein

Cyclin-T

Gene

CycT

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II).

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionCyclin
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-112382, Formation of RNA Pol II elongation complex
R-DME-2173796, SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
R-DME-674695, RNA Polymerase II Pre-transcription Events
R-DME-6796648, TP53 Regulates Transcription of DNA Repair Genes
R-DME-6807505, RNA polymerase II transcribes snRNA genes
R-DME-75955, RNA Polymerase II Transcription Elongation
R-DME-9018519, Estrogen-dependent gene expression

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
O96433

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cyclin-T
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CycT
ORF Names:CG6292
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0025455, CycT

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000804981 – 1097Cyclin-TAdd BLAST1097

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei916Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O96433

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O96433

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0025455, Expressed in imaginal disc and 42 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O96433, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O96433, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the super elongation complex (SEC), at least composed of Ell, Cdk9, cyclin-T (CycT), lilli and ear. Associates with CDK9 to form P-TEFb.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
65249, 11 interactors

Database of interacting proteins

More...
DIPi
DIP-29892N

Protein interaction database and analysis system

More...
IntActi
O96433, 4 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0305335

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O96433

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi15 – 21Poly-Ser7
Compositional biasi382 – 390Poly-Ser9
Compositional biasi426 – 429Poly-Ser4
Compositional biasi441 – 449Poly-Ser9
Compositional biasi553 – 556Poly-Pro4
Compositional biasi598 – 603Poly-Gln6
Compositional biasi872 – 880Poly-Lys9
Compositional biasi993 – 998Poly-Gly6

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the cyclin family. Cyclin C subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0834, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000170249

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_283750_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O96433

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O96433

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00043, CYCLIN, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028863, CCNT1
IPR013763, Cyclin-like
IPR036915, Cyclin-like_sf
IPR043198, Cyclin/Ssn8
IPR006671, Cyclin_N

The PANTHER Classification System

More...
PANTHERi
PTHR10026, PTHR10026, 1 hit
PTHR10026:SF131, PTHR10026:SF131, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00134, Cyclin_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00385, CYCLIN, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47954, SSF47954, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform B (identifier: O96433-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSLLATPMPQ AATASSSSSA SAAASASGIP ITANNNLPFE KDKIWYFSND
60 70 80 90 100
QLANSPSRRC GIKGDDELQY RQMTAYLIQE MGQRLQVSQL CINTAIVYMH
110 120 130 140 150
RFYAFHSFTH FHRNSMASAS LFLAAKVEEQ PRKLEHVIRA ANKCLPPTTE
160 170 180 190 200
QNYAELAQEL VFNENVLLQT LGFDVAIDHP HTHVVRTCQL VKACKDLAQT
210 220 230 240 250
SYFLASNSLH LTSMCLQYRP TVVACFCIYL ACKWSRWEIP QSTEGKHWFY
260 270 280 290 300
YVDKTVSLDL LKQLTDEFIA IYEKSPARLK SKLNSIKAIA QGASNRTANS
310 320 330 340 350
KDKPKEDWKI TEMMKGYHSN ITTPPELLNG NDSRDRDRDR ERERERERDP
360 370 380 390 400
SSLLPPPAMV PQQRRQDGGH QRSSSVSGVP GSSSSSSSSS HKMPNYPGGM
410 420 430 440 450
PPDAHTDHKS KQPGYNNRMP SSHQRSSSSG LGSSGSGSQR SSSSSSSSSQ
460 470 480 490 500
QPGRPSMPVD YHKSSRGMPP VGVGMPPHGS HKMTSGSKPQ QPQQQPVPHP
510 520 530 540 550
SASNSSASGM SSKDKSQSNK MYPNAPPPYS NSAPQNPLMS RGGYPGASNG
560 570 580 590 600
SQPPPPAGYG GHRSKSGSTV HGMPPFEQQL PYSQSQSYGH MQQQPVPQSQ
610 620 630 640 650
QQQMPPEASQ HSLQSKNSLF SPEWPDIKKE PMSQSQPQPF NGLLPPPAPP
660 670 680 690 700
GHDYKLNSHP RDKESPKKER LTPTKKDKHR PVMPPVGSGN SSSGSGSSKP
710 720 730 740 750
MLPPHKKQIP HGGDLLTNPG ESGSLKRPNE ISGSQYGLNK LDEIDNSNMP
760 770 780 790 800
REKLRKLDTT TGLPTYPNYE EKHTPLNMSN GIETTPDLVR SLLKESLCPS
810 820 830 840 850
NASLLKPDAL TMPGLKPPAE LLEPMPAPAT IKKEQGITPM TSLASGPAPM
860 870 880 890 900
DLEVPTKQAG EIKEESSSKS EKKKKKDKHK HKEKDKSKDK TEKEERKKHK
910 920 930 940 950
KDKQKDRSGS GGSKDSSLPN EPLKMVIKNP NGSLQAGASA PIKLKISKNK
960 970 980 990 1000
VEPNNYSAAA GLPGAIGYGL PPTTATTTSA SIGAAAPVLP PYGAGGGGYS
1010 1020 1030 1040 1050
SSGGSSSGGS SKKKHSDRDR DKESKKNKSQ DYAKYNGAGG GIFNPLGGAG
1060 1070 1080 1090
AAPNMSGGMG APMSTAVPPS MLLAPTGAVP PSAAGLAPPP MPVYNKK
Length:1,097
Mass (Da):118,269
Last modified:May 10, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0E0E71B8A674FC5B
GO
Isoform A (identifier: O96433-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-213: Missing.

Show »
Length:884
Mass (Da):94,591
Checksum:iD465DED0CBFA2B81
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M9PFT9M9PFT9_DROME
Cyclin T, isoform C
CycT anon-74EFc, CycT-RB, Dmcyclin T, Dmel\CG6292, dT
1,097Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9PI89M9PI89_DROME
Cyclin T, isoform D
CycT anon-74EFc, Dmcyclin T, Dmel\CG6292, dT, ORE-14
884Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti55S → L in AAC73052 (PubMed:9593731).Curated1
Sequence conflicti403D → E in AAC73052 (PubMed:9593731).Curated1
Sequence conflicti406T → P in AAC73052 (PubMed:9593731).Curated1
Sequence conflicti440R → H in AAC73052 (PubMed:9593731).Curated1
Sequence conflicti575P → H in AAC73052 (PubMed:9593731).Curated1
Sequence conflicti639P → L in AAC73052 (PubMed:9593731).Curated1
Sequence conflicti686V → M in AAC73052 (PubMed:9593731).Curated1
Sequence conflicti901K → R in AAC73052 (PubMed:9593731).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0102901 – 213Missing in isoform A. CuratedAdd BLAST213

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF051933 mRNA Translation: AAC73052.1
AE014296 Genomic DNA Translation: AAF49325.1
AE014296 Genomic DNA Translation: AAS64974.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T13033

NCBI Reference Sequences

More...
RefSeqi
NP_001261992.1, NM_001275063.2 [O96433-1]
NP_001261993.1, NM_001275064.2 [O96433-2]
NP_524127.2, NM_079403.4 [O96433-1]
NP_996117.1, NM_206395.3 [O96433-2]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0075205; FBpp0074968; FBgn0025455 [O96433-1]
FBtr0075206; FBpp0089275; FBgn0025455 [O96433-2]
FBtr0333124; FBpp0305335; FBgn0025455 [O96433-1]
FBtr0333125; FBpp0305336; FBgn0025455 [O96433-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
39961

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG6292

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF051933 mRNA Translation: AAC73052.1
AE014296 Genomic DNA Translation: AAF49325.1
AE014296 Genomic DNA Translation: AAS64974.1
PIRiT13033
RefSeqiNP_001261992.1, NM_001275063.2 [O96433-1]
NP_001261993.1, NM_001275064.2 [O96433-2]
NP_524127.2, NM_079403.4 [O96433-1]
NP_996117.1, NM_206395.3 [O96433-2]

3D structure databases

SMRiO96433
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi65249, 11 interactors
DIPiDIP-29892N
IntActiO96433, 4 interactors
STRINGi7227.FBpp0305335

PTM databases

iPTMnetiO96433

Proteomic databases

PaxDbiO96433

Genome annotation databases

EnsemblMetazoaiFBtr0075205; FBpp0074968; FBgn0025455 [O96433-1]
FBtr0075206; FBpp0089275; FBgn0025455 [O96433-2]
FBtr0333124; FBpp0305335; FBgn0025455 [O96433-1]
FBtr0333125; FBpp0305336; FBgn0025455 [O96433-2]
GeneIDi39961
KEGGidme:Dmel_CG6292

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
13067
FlyBaseiFBgn0025455, CycT

Phylogenomic databases

eggNOGiKOG0834, Eukaryota
GeneTreeiENSGT00940000170249
HOGENOMiCLU_283750_0_0_1
InParanoidiO96433
PhylomeDBiO96433

Enzyme and pathway databases

ReactomeiR-DME-112382, Formation of RNA Pol II elongation complex
R-DME-2173796, SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
R-DME-674695, RNA Polymerase II Pre-transcription Events
R-DME-6796648, TP53 Regulates Transcription of DNA Repair Genes
R-DME-6807505, RNA polymerase II transcribes snRNA genes
R-DME-75955, RNA Polymerase II Transcription Elongation
R-DME-9018519, Estrogen-dependent gene expression
SignaLinkiO96433

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
39961, 0 hits in 3 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
39961

Protein Ontology

More...
PROi
PR:O96433

Gene expression databases

BgeeiFBgn0025455, Expressed in imaginal disc and 42 other tissues
ExpressionAtlasiO96433, baseline and differential
GenevisibleiO96433, DM

Family and domain databases

CDDicd00043, CYCLIN, 1 hit
InterProiView protein in InterPro
IPR028863, CCNT1
IPR013763, Cyclin-like
IPR036915, Cyclin-like_sf
IPR043198, Cyclin/Ssn8
IPR006671, Cyclin_N
PANTHERiPTHR10026, PTHR10026, 1 hit
PTHR10026:SF131, PTHR10026:SF131, 1 hit
PfamiView protein in Pfam
PF00134, Cyclin_N, 1 hit
SMARTiView protein in SMART
SM00385, CYCLIN, 2 hits
SUPFAMiSSF47954, SSF47954, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCCNT_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O96433
Secondary accession number(s): Q9VVI6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 10, 2004
Last modified: February 10, 2021
This is version 165 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
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