Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
We will be switching to the new UniProt website soon. Please explore and share your feedback. Take me to the new website.

UniProtKB - O96015 (DNAL4_HUMAN)

Entry version 163 (23 Feb 2022)
Sequence version 1 (01 May 1999)
Previous versions | rss
Add a publicationFeedback
Protein

Dynein axonemal light chain 4

Gene

DNAL4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity).

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMotor protein

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		O96015

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-177504, Retrograde neurotrophin signalling

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		O96015

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Dynein axonemal light chain 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DNAL4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:2955, DNAL4

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		610565, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_O96015

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000100246

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton, Dynein, Microtubule

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Mirror movements 3 (MRMV3)1 Publication
The disease is caused by variants affecting the gene represented in this entry.
Disease descriptionA disorder characterized by contralateral involuntary movements that mirror voluntary ones. While mirror movements are occasionally found in young children, persistence beyond the age of 10 is abnormal. Mirror movements occur more commonly in the upper extremities.
Related information in OMIM

Organism-specific databases

DisGeNET

More...DisGeNETi		10126

MalaCards human disease database

More...MalaCardsi		DNAL4
MIMi616059, phenotype

Open Targets

More...OpenTargetsi		ENSG00000100246

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...Orphaneti		238722, Familial congenital mirror movements

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA27426

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		O96015, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		DNAL4

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001951361 – 105Dynein axonemal light chain 4Add BLAST105

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		O96015

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		O96015

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O96015

PeptideAtlas

More...PeptideAtlasi		O96015

PRoteomics IDEntifications database

More...PRIDEi		O96015

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		51197

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O96015

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O96015

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000100246, Expressed in left testis and 171 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		O96015, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O96015, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000100246, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Consists of at least two heavy chains and a number of intermediate and light chains.

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		115430, 39 interactors

Protein interaction database and analysis system

More...IntActi		O96015, 15 interactors

Molecular INTeraction database

More...MINTi		O96015

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000216068

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		O96015, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		O96015

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the dynein light chain family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3430, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000161265

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_070944_3_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O96015

Identification of Orthologs from Complete Genome Data

More...OMAi		YMFFGGN

Database of Orthologous Groups

More...OrthoDBi		1520814at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O96015

TreeFam database of animal gene trees

More...TreeFami		TF324136

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.740.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR037177, DLC_sf
IPR001372, Dynein_light_chain_typ-1/2

The PANTHER Classification System

More...PANTHERi		PTHR11886, PTHR11886, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01221, Dynein_light, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01375, Dynein_light, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54648, SSF54648, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

O96015-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGETEGKKDE ADYKRLQTFP LVRHSDMPEE MRVETMELCV TACEKFSNNN 
        60         70         80         90        100
ESAAKMIKET MDKKFGSSWH VVIGEGFGFE ITHEVKNLLY LYFGGTLAVC 

VWKCS
Length:105
Mass (Da):12,009
Last modified:May 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD0AE8929DEB2AC06
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B0QXZ5B0QXZ5_HUMAN
Dynein light chain
DNAL4
68Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti58K → N in CAG46992 (Ref. 6) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL035366 mRNA Translation: CAA23018.1
BT009847 mRNA Translation: AAP88849.1
AY453399 mRNA Translation: AAS47516.1
CR456487 mRNA Translation: CAG30373.1
AK290566 mRNA Translation: BAF83255.1
CR542177 mRNA Translation: CAG46974.1
CR542195 mRNA Translation: CAG46992.1
AL008583 Genomic DNA No translation available.
CH471095 Genomic DNA Translation: EAW60272.1
BC002968 mRNA Translation: AAH02968.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS13979.1

NCBI Reference Sequences

More...RefSeqi		NP_005731.1, NM_005740.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000216068; ENSP00000216068; ENSG00000100246

Database of genes from NCBI RefSeq genomes

More...GeneIDi		10126

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:10126

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000216068.9; ENSP00000216068.4; NM_005740.3; NP_005731.1

UCSC genome browser

More...UCSCi		uc003awj.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035366 mRNA Translation: CAA23018.1
BT009847 mRNA Translation: AAP88849.1
AY453399 mRNA Translation: AAS47516.1
CR456487 mRNA Translation: CAG30373.1
AK290566 mRNA Translation: BAF83255.1
CR542177 mRNA Translation: CAG46974.1
CR542195 mRNA Translation: CAG46992.1
AL008583 Genomic DNA No translation available.
CH471095 Genomic DNA Translation: EAW60272.1
BC002968 mRNA Translation: AAH02968.1
CCDSiCCDS13979.1
RefSeqiNP_005731.1, NM_005740.2

3D structure databases

SMRiO96015
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi115430, 39 interactors
IntActiO96015, 15 interactors
MINTiO96015
STRINGi9606.ENSP00000216068

PTM databases

iPTMnetiO96015
PhosphoSitePlusiO96015

Genetic variation databases

BioMutaiDNAL4

Proteomic databases

EPDiO96015
MassIVEiO96015
PaxDbiO96015
PeptideAtlasiO96015
PRIDEiO96015
ProteomicsDBi51197

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		329, 272 antibodies from 29 providers

The DNASU plasmid repository

More...DNASUi		10126

Genome annotation databases

EnsembliENST00000216068; ENSP00000216068; ENSG00000100246
GeneIDi10126
KEGGihsa:10126
MANE-SelectiENST00000216068.9; ENSP00000216068.4; NM_005740.3; NP_005731.1
UCSCiuc003awj.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		10126
DisGeNETi10126

GeneCards: human genes, protein and diseases

More...GeneCardsi		DNAL4
HGNCiHGNC:2955, DNAL4
HPAiENSG00000100246, Low tissue specificity
MalaCardsiDNAL4
MIMi610565, gene
616059, phenotype
neXtProtiNX_O96015
OpenTargetsiENSG00000100246
Orphaneti238722, Familial congenital mirror movements
PharmGKBiPA27426
VEuPathDBiHostDB:ENSG00000100246

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3430, Eukaryota
GeneTreeiENSGT00940000161265
HOGENOMiCLU_070944_3_0_1
InParanoidiO96015
OMAiYMFFGGN
OrthoDBi1520814at2759
PhylomeDBiO96015
TreeFamiTF324136

Enzyme and pathway databases

PathwayCommonsiO96015
ReactomeiR-HSA-177504, Retrograde neurotrophin signalling
SignaLinkiO96015

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		10126, 7 hits in 1044 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		DNAL4, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		DNAL4

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		10126
PharosiO96015, Tbio

Protein Ontology

More...PROi		PR:O96015
RNActiO96015, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000100246, Expressed in left testis and 171 other tissues
ExpressionAtlasiO96015, baseline and differential
GenevisibleiO96015, HS

Family and domain databases

Gene3Di3.30.740.10, 1 hit
InterProiView protein in InterPro
IPR037177, DLC_sf
IPR001372, Dynein_light_chain_typ-1/2
PANTHERiPTHR11886, PTHR11886, 1 hit
PfamiView protein in Pfam
PF01221, Dynein_light, 1 hit
SMARTiView protein in SMART
SM01375, Dynein_light, 1 hit
SUPFAMiSSF54648, SSF54648, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDNAL4_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O96015
Secondary accession number(s): Q6FGB2, Q6FGD0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 20, 2002
Last sequence update: May 1, 1999
Last modified: February 23, 2022
This is version 163 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again