Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative transmembrane protein CXorf1

Gene

CXorf1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Caution

Product of a dubious CDS prediction. Most probably an erroneously predicted open reading frame in the 3' UTR of the SLITRK2 gene.Curated

Names & Taxonomyi

Protein namesi
Recommended name:
Putative transmembrane protein CXorf1Curated
Gene namesi
Name:CXorf11 Publication
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

EuPathDBiHostDB:ENSG00000221870.2
MIMi300565 gene
neXtProtiNX_O96002

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei23 – 43HelicalSequence analysisAdd BLAST21
Transmembranei58 – 78HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185985
PharmGKBiPA27059

Polymorphism and mutation databases

BioMutaiTMEM257

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000797291 – 111Putative transmembrane protein CXorf1Add BLAST111

Proteomic databases

PaxDbiO96002
PRIDEiO96002
ProteomicsDBi51182

PTM databases

iPTMnetiO96002
PhosphoSitePlusiO96002

Expressioni

Tissue specificityi

Brain. In the hippocampus it is mainly localized in the granular-cell layer of the dentate gyrus and in the CA2-CA3 subfields of Ammon's horn.1 Publication

Gene expression databases

BgeeiENSG00000221870 Expressed in 61 organ(s), highest expression level in caudate nucleus
CleanExiHS_CXorf1
ExpressionAtlasiO96002 baseline and differential
GenevisibleiO96002 HS

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000386149

Structurei

3D structure databases

ProteinModelPortaliO96002
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410KCJN Eukaryota
ENOG4110NW9 LUCA
GeneTreeiENSGT00930000150809
HOGENOMiHOG000112096
InParanoidiO96002
OMAiYRMRSPR
OrthoDBiEOG091G0WPJ
PhylomeDBiO96002

Sequencei

Sequence statusi: Complete.

O96002-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYSRLFYLKS SYIIYFEPLF SNAIINILSF INSLASPLTI FCFALSAQAL
60 70 80 90 100
STIFYFRIFI FIFHSWILLF HFYFTCSFKT YEHQHSKMVP AYRMQSPRAL
110
PRTYLYVWPY K
Length:111
Mass (Da):13,452
Last modified:May 1, 1999 - v1
Checksum:i5EFA883C1329A522
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03376636S → A. Corresponds to variant dbSNP:rs3752359Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y10607 Genomic DNA Translation: CAA71614.1
Y08902 mRNA Translation: CAA70110.1
AL109653 Genomic DNA No translation available.
BC113600 mRNA Translation: AAI13601.1
BC113604 mRNA Translation: AAI13605.1
RefSeqiNP_004700.1, NM_004709.2
UniGeneiHs.106688
Hs.320368

Genome annotation databases

UCSCiuc004fch.4 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y10607 Genomic DNA Translation: CAA71614.1
Y08902 mRNA Translation: CAA70110.1
AL109653 Genomic DNA No translation available.
BC113600 mRNA Translation: AAI13601.1
BC113604 mRNA Translation: AAI13605.1
RefSeqiNP_004700.1, NM_004709.2
UniGeneiHs.106688
Hs.320368

3D structure databases

ProteinModelPortaliO96002
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000386149

PTM databases

iPTMnetiO96002
PhosphoSitePlusiO96002

Polymorphism and mutation databases

BioMutaiTMEM257

Proteomic databases

PaxDbiO96002
PRIDEiO96002
ProteomicsDBi51182

Protocols and materials databases

DNASUi9142
Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc004fch.4 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000221870.2
H-InvDBiHIX0056114
MIMi300565 gene
neXtProtiNX_O96002
OpenTargetsiENSG00000185985
PharmGKBiPA27059

Phylogenomic databases

eggNOGiENOG410KCJN Eukaryota
ENOG4110NW9 LUCA
GeneTreeiENSGT00930000150809
HOGENOMiHOG000112096
InParanoidiO96002
OMAiYRMRSPR
OrthoDBiEOG091G0WPJ
PhylomeDBiO96002

Miscellaneous databases

GenomeRNAii9142
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000221870 Expressed in 61 organ(s), highest expression level in caudate nucleus
CleanExiHS_CXorf1
ExpressionAtlasiO96002 baseline and differential
GenevisibleiO96002 HS

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiCX001_HUMAN
AccessioniPrimary (citable) accession number: O96002
Secondary accession number(s): Q14CW0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: November 7, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again