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Protein

Disks large-associated protein 3

Gene

DLGAP3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6794361 Neurexins and neuroligins

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Disks large-associated protein 3
Short name:
DAP-3
Alternative name(s):
PSD-95/SAP90-binding protein 3
SAP90/PSD-95-associated protein 3
Short name:
SAPAP3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DLGAP3
Synonyms:DAP3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000116544.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30368 DLGAP3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611413 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O95886

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell junction, Cell membrane, Membrane, Postsynaptic cell membrane, Synapse

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
58512

Open Targets

More...
OpenTargetsi
ENSG00000116544

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134923893

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
DLGAP3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001742941 – 979Disks large-associated protein 3Add BLAST979

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei58PhosphoserineBy similarity1
Modified residuei406PhosphoserineBy similarity1
Modified residuei409PhosphoserineBy similarity1
Modified residuei412PhosphoserineBy similarity1
Modified residuei416PhosphoserineBy similarity1
Modified residuei643PhosphoserineBy similarity1
Modified residuei645PhosphoserineBy similarity1
Modified residuei932PhosphoserineBy similarity1
Modified residuei935PhosphoserineBy similarity1
Modified residuei967PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O95886

PeptideAtlas

More...
PeptideAtlasi
O95886

PRoteomics IDEntifications database

More...
PRIDEi
O95886

ProteomicsDB human proteome resource

More...
ProteomicsDBi
51118

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O95886

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O95886

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
O95886

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000116544 Expressed in 85 organ(s), highest expression level in prefrontal cortex

CleanEx database of gene expression profiles

More...
CleanExi
HS_DAP3
HS_DLGAP3

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O95886 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA026445

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with DLG4/PSD-95.By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
NCK1P163332EBI-1752541,EBI-389883

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
121839, 8 interactors

Protein interaction database and analysis system

More...
IntActi
O95886, 14 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000235180

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
O95886

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O95886

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi223 – 234Poly-HisAdd BLAST12

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SAPAP family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3971 Eukaryota
ENOG4111JKV LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159513

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000015346

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG018957

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O95886

Identification of Orthologs from Complete Genome Data

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OMAi
RASPCHR

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0J9O

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O95886

TreeFam database of animal gene trees

More...
TreeFami
TF321382

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR030526 DLGAP3
IPR005026 SAPAP

The PANTHER Classification System

More...
PANTHERi
PTHR12353 PTHR12353, 1 hit
PTHR12353:SF4 PTHR12353:SF4, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03359 GKAP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O95886-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRGYHGDRGS HPRPARFADQ QHMDVGPAAR APYLLGSREA FSTEPRFCAP
60 70 80 90 100
RAGLGHISPE GPLSLSEGPS VGPEGGPAGA GVGGGSSTFP RMYPGQGPFD
110 120 130 140 150
TCEDCVGHPQ GKGAPRLPPT LLDQFEKQLP VQQDGFHTLP YQRGPAGAGP
160 170 180 190 200
GPAPGTGTAP EPRSESPSRI RHLVHSVQKL FAKSHSLEAP GKRDYNGPKA
210 220 230 240 250
EGRGGSGGDS YPGPGSGGPH TSHHHHHHHH HHHHQSRHGK RSKSKDRKGD
260 270 280 290 300
GRHQAKSTGW WSSDDNLDSD SGFLAGGRPP GEPGGPFCLE GPDGSYRDLS
310 320 330 340 350
FKGRSGGSEG RCLACTGMSM SLDGQSVKRS AWHTMMVSQG RDGYPGAGPG
360 370 380 390 400
KGLLGPETKA KARTYHYLQV PQDDWGGYPT GGKDGEIPCR RMRSGSYIKA
410 420 430 440 450
MGDEESGDSD GSPKTSPKAV ARRFTTRRSS SVDQARINCC VPPRIHPRSS
460 470 480 490 500
IPGYSRSLTT GQLSDELNQQ LEAVCGSVFG ELESQAVDAL DLPGCFRMRS
510 520 530 540 550
HSYLRAIQAG CSQDDDCLPL LATPAAVSGR PGSSFNFRKA PPPIPPGSQA
560 570 580 590 600
PPRISITAQS STDSAHESFT AAEGPARRCS SADGLDGPAM GARTLELAPV
610 620 630 640 650
PPRASPKPPT LIIKTIPGRE ELRSLARQRK WRPSIGVQVE TISDSDTENR
660 670 680 690 700
SRREFHSIGV QVEEDKRRAR FKRSNSVTAG VQADLELEGL AGLATVATED
710 720 730 740 750
KALQFGRSFQ RHASEPQPGP RAPTYSVFRT VHTQGQWAYR EGYPLPYEPP
760 770 780 790 800
ATDGSPGPAP APTPGPGAGR RDSWIERGSR SLPDSGRASP CPRDGEWFIK
810 820 830 840 850
MLRAEVEKLE HWCQQMEREA EDYELPEEIL EKIRSAVGST QLLLSQKVQQ
860 870 880 890 900
FFRLCQQSMD PTAFPVPTFQ DLAGFWDLLQ LSIEDVTLKF LELQQLKANS
910 920 930 940 950
WKLLEPKEEK KVPPPIPKKP LRGRGVPVKE RSLDSVDRQR QEARKRLLAA
960 970
KRAASFRHSS ATESADSIEI YIPEAQTRL
Length:979
Mass (Da):106,040
Last modified:July 19, 2005 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i34A010D792CFFB9D
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAD20042 differs from that shown. Reason: Frameshift at position 833.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_079371763T → P1 PublicationCorresponds to variant dbSNP:rs758215471Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC114490 Genomic DNA No translation available.
AL122010 Genomic DNA No translation available.
AF131778 mRNA Translation: AAD20042.1 Frameshift.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS30670.1

NCBI Reference Sequences

More...
RefSeqi
NP_001073887.1, NM_001080418.2
XP_011540181.1, XM_011541879.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.436393
Hs.733945

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000235180; ENSP00000235180; ENSG00000116544
ENST00000373347; ENSP00000362444; ENSG00000116544

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
58512

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:58512

UCSC genome browser

More...
UCSCi
uc001byc.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC114490 Genomic DNA No translation available.
AL122010 Genomic DNA No translation available.
AF131778 mRNA Translation: AAD20042.1 Frameshift.
CCDSiCCDS30670.1
RefSeqiNP_001073887.1, NM_001080418.2
XP_011540181.1, XM_011541879.2
UniGeneiHs.436393
Hs.733945

3D structure databases

ProteinModelPortaliO95886
SMRiO95886
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi121839, 8 interactors
IntActiO95886, 14 interactors
STRINGi9606.ENSP00000235180

PTM databases

iPTMnetiO95886
PhosphoSitePlusiO95886
SwissPalmiO95886

Polymorphism and mutation databases

BioMutaiDLGAP3

Proteomic databases

PaxDbiO95886
PeptideAtlasiO95886
PRIDEiO95886
ProteomicsDBi51118

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000235180; ENSP00000235180; ENSG00000116544
ENST00000373347; ENSP00000362444; ENSG00000116544
GeneIDi58512
KEGGihsa:58512
UCSCiuc001byc.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
58512
DisGeNETi58512
EuPathDBiHostDB:ENSG00000116544.11

GeneCards: human genes, protein and diseases

More...
GeneCardsi
DLGAP3
HGNCiHGNC:30368 DLGAP3
HPAiHPA026445
MIMi611413 gene
neXtProtiNX_O95886
OpenTargetsiENSG00000116544
PharmGKBiPA134923893

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3971 Eukaryota
ENOG4111JKV LUCA
GeneTreeiENSGT00940000159513
HOGENOMiHOG000015346
HOVERGENiHBG018957
InParanoidiO95886
OMAiRASPCHR
OrthoDBiEOG091G0J9O
PhylomeDBiO95886
TreeFamiTF321382

Enzyme and pathway databases

ReactomeiR-HSA-6794361 Neurexins and neuroligins

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
58512

Protein Ontology

More...
PROi
PR:O95886

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000116544 Expressed in 85 organ(s), highest expression level in prefrontal cortex
CleanExiHS_DAP3
HS_DLGAP3
GenevisibleiO95886 HS

Family and domain databases

InterProiView protein in InterPro
IPR030526 DLGAP3
IPR005026 SAPAP
PANTHERiPTHR12353 PTHR12353, 1 hit
PTHR12353:SF4 PTHR12353:SF4, 1 hit
PfamiView protein in Pfam
PF03359 GKAP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDLGP3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O95886
Secondary accession number(s): Q5TDD5, Q9H3X7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: July 19, 2005
Last modified: December 5, 2018
This is version 126 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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