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Entry version 140 (13 Feb 2019)
Sequence version 2 (22 Jul 2008)
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Protein

Zinc finger MYM-type protein 6

Gene

ZMYM6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in the regulation of cell morphology and cytoskeletal organization.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri113 – 151MYM-type 1Add BLAST39
Zinc fingeri163 – 206MYM-type 2Add BLAST44
Zinc fingeri213 – 248MYM-type 3Add BLAST36
Zinc fingeri296 – 334MYM-type 4Add BLAST39
Zinc fingeri342 – 443MYM-type 5Add BLAST102
Zinc fingeri451 – 485MYM-type 6Add BLAST35
Zinc fingeri492 – 531MYM-type 7Add BLAST40
Zinc fingeri538 – 572MYM-type 8Add BLAST35

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • DNA binding Source: ProtInc
  • zinc ion binding Source: InterPro

GO - Biological processi

  • cytoskeleton organization Source: UniProtKB
  • multicellular organism development Source: ProtInc
  • regulation of cell morphogenesis Source: UniProtKB

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger MYM-type protein 6
Alternative name(s):
Transposon-derived Buster2 transposase-like protein
Zinc finger protein 258
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZMYM6
Synonyms:Buster2, KIAA1353, ZNF258
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000163867.16

Human Gene Nomenclature Database

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HGNCi
HGNC:13050 ZMYM6

Online Mendelian Inheritance in Man (OMIM)

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MIMi
613567 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O95789

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000163867

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37628

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZMYM6

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001913811 – 1325Zinc finger MYM-type protein 6Add BLAST1325

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei397PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
O95789

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
O95789

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O95789

PeptideAtlas

More...
PeptideAtlasi
O95789

PRoteomics IDEntifications database

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PRIDEi
O95789

ProteomicsDB human proteome resource

More...
ProteomicsDBi
51049
51050 [O95789-1]
51051 [O95789-2]
51052 [O95789-4]
51053 [O95789-5]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O95789

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O95789

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed at high levels in heart, skeletal muscle, kidney and liver.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000163867 Expressed in 180 organ(s), highest expression level in adrenal tissue

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
O95789 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
O95789 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA011004
HPA071865

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
114638, 51 interactors

Protein interaction database and analysis system

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IntActi
O95789, 6 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000349708

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
O95789

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
O95789

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri113 – 151MYM-type 1Add BLAST39
Zinc fingeri163 – 206MYM-type 2Add BLAST44
Zinc fingeri213 – 248MYM-type 3Add BLAST36
Zinc fingeri296 – 334MYM-type 4Add BLAST39
Zinc fingeri342 – 443MYM-type 5Add BLAST102
Zinc fingeri451 – 485MYM-type 6Add BLAST35
Zinc fingeri492 – 531MYM-type 7Add BLAST40
Zinc fingeri538 – 572MYM-type 8Add BLAST35

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IE8I Eukaryota
ENOG410XQR6 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159550
ENSGT00940000162386

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG058050

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
O95789

Identification of Orthologs from Complete Genome Data

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OMAi
TIGHRID

Database of Orthologous Groups

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OrthoDBi
587724at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
O95789

TreeFam database of animal gene trees

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TreeFami
TF336988

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR012337 RNaseH-like_sf
IPR026625 TFII-I-rel
IPR011017 TRASH_dom
IPR010507 Znf_MYM

The PANTHER Classification System

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PANTHERi
PTHR11697 PTHR11697, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF06467 zf-FCS, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00746 TRASH, 9 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53098 SSF53098, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 5 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 3 (identifier: O95789-3) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKEPLDGECG KAVVPQQELL DKIKEEPDNA QEYGCVQQPK TQESKLKIGG
60 70 80 90 100
VSSVNERPIA QQLNPGFQLS FASSGPSVLL PSVPAVAIKV FCSGCKKMLY
110 120 130 140 150
KGQTAYHKTG STQLFCSTRC ITRHSSPACL PPPPKKTCTN CSKDILNPKD
160 170 180 190 200
VITTRFENSY PSKDFCSQSC LSSYELKKKP VVTIYTKSIS TKCSMCQKNA
210 220 230 240 250
DTRFEVKYQN VVHGLCSDAC FSKFHSTNNL TMNCCENCGS YCYSSSGPCQ
260 270 280 290 300
SQKVFSSTSV TAYKQNSAQI PPYALGKSLR PSAEMIETTN DSGKTELFCS
310 320 330 340 350
INCLSAYRVK TVTSSGVQVS CHSCKTSAIP QYHLAMSNGT IYSFCSSSCV
360 370 380 390 400
VAFQNVFSKP KGTNSSAVPL SQGQVVVSPP SSRSAVSIGG GNTSAVSPSS
410 420 430 440 450
IRGSAAASLQ PLAEQSQQVA LTHTVVKLKC QHCNHLFATK PELLFYKGKM
460 470 480 490 500
FLFCGKNCSD EYKKKNKVVA MCDYCKLQKI IKETVRFSGV DKPFCSEVCK
510 520 530 540 550
FLSARDFGER WGNYCKMCSY CSQTSPNLVE NRLEGKLEEF CCEDCMSKFT
560 570 580 590 600
VLFYQMAKCD GCKRQGKLSE SIKWRGNIKH FCNLFCVLEF CHQQIMNDCL
610 620 630 640 650
PQNKVNISKA KTAVTELPSA RTDTTPVITS VMSLAKIPAT LSTGNTNSVL
660 670 680 690 700
KGAVTKEAAK IIQDESTQED AMKFPSSQSS QPSRLLKNKG ISCKPVTQTK
710 720 730 740 750
ATSCKPHTQH KECQTDLPMP NEKNDAELDS PPSKKKRLGF FQTYDTEYLK
760 770 780 790 800
VGFIICPGSK ESSPRPQCVI CGEILSSENM KPANLSHHLK TKHSELENKP
810 820 830 840 850
VDFFEQKSLE MECQNSSLKK CLLVEKSLVK ASYLIAFQTA ASKKPFSIAE
860 870 880 890 900
ELIKPYLVEM CSEVLGSSAG DKMKTIPLSN VTIQHRIDEL SADIEDQLIQ
910 920 930 940 950
KVRESKWFAL QIDESSEISN ITLLLCYIRF IDYDCRDVKE ELLFCIEMPT
960 970 980 990 1000
QITGFEIFEL INKYIDSKSL NWKHCVGLCT DGAASMTGRY SGLKAKIQEV
1010 1020 1030 1040 1050
AMNTAAFTHC FIHRERLVAE KLSPCLHKIL LQSAQILSFI KSNALNSRML
1060 1070 1080 1090 1100
TILCEEMGSE HVSLPLHAEV RWISRGRMLK RLFELRHEIE IFLSQKHSDL
1110 1120 1130 1140 1150
AKYFHDEEWV GKLAYLSDIF SLINELNLSL QGTLTTFFNL CNKIDVFKRK
1160 1170 1180 1190 1200
LKMWLKRTQE NDYDMFPSFS EFSNSSGLNM TDITRIIFEH LEGLSQVFSD
1210 1220 1230 1240 1250
CFPPEQDLRS GNLWIIHPFM NHQNNNLTDF EEEKLTELSS DLGLQALFKS
1260 1270 1280 1290 1300
VSVTQFWINA KTSYPELHER AMKFLLPFST VYLCDAAFSA LTESKQKNLL
1310 1320
GSGPALRLAV TSLIPRIEKL VKEKE
Length:1,325
Mass (Da):148,089
Last modified:July 22, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1BC8ADE286A27F5A
GO
Isoform 2 (identifier: O95789-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     144-156: DILNPKDVITTRF → YKILNIPFYFTFF
     157-1325: Missing.

Show »
Length:156
Mass (Da):17,121
Checksum:iFC5EF17AD7116337
GO
Isoform 1 (identifier: O95789-1) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     716-723: DLPMPNEK → ECPVRAVC
     724-1325: Missing.

Show »
Length:723
Mass (Da):79,113
Checksum:iF2F654CA86A24660
GO
Isoform 4 (identifier: O95789-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     144-170: DILNPKDVITTRFENSYPSKDFCSQSC → YKILNIPFYFTFFLVCILFSSNILLIL
     171-1325: Missing.

Note: No experimental confirmation available.
Show »
Length:170
Mass (Da):18,664
Checksum:i66B082068291909A
GO
Isoform 5 (identifier: O95789-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-687: Missing.
     688-715: NKGISCKPVTQTKATSCKPHTQHKECQT → MNFKYVGRYIKNIAYLFLKITVIQIFHS

Note: No experimental confirmation available.
Show »
Length:638
Mass (Da):73,255
Checksum:i147A835A111ADCFD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
X6RCN5X6RCN5_HUMAN
Zinc finger MYM-type protein 6
ZMYM6
208Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH33903 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence AAI07881 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence BAA92591 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti44S → G in AAI07881 (PubMed:15489334).Curated1
Sequence conflicti413A → G in AAD15797 (PubMed:10486218).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_044432660K → R. Corresponds to variant dbSNP:rs10158256Ensembl.1
Natural variantiVAR_0444331233E → K. Corresponds to variant dbSNP:rs16837147Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0352871 – 687Missing in isoform 5. 1 PublicationAdd BLAST687
Alternative sequenceiVSP_034680144 – 170DILNP…CSQSC → YKILNIPFYFTFFLVCILFS SNILLIL in isoform 4. 2 PublicationsAdd BLAST27
Alternative sequenceiVSP_011446144 – 156DILNP…ITTRF → YKILNIPFYFTFF in isoform 2. 1 PublicationAdd BLAST13
Alternative sequenceiVSP_011447157 – 1325Missing in isoform 2. 1 PublicationAdd BLAST1169
Alternative sequenceiVSP_034681171 – 1325Missing in isoform 4. 2 PublicationsAdd BLAST1155
Alternative sequenceiVSP_035288688 – 715NKGIS…KECQT → MNFKYVGRYIKNIAYLFLKI TVIQIFHS in isoform 5. 1 PublicationAdd BLAST28
Alternative sequenceiVSP_034682716 – 723DLPMPNEK → ECPVRAVC in isoform 1. 1 Publication8
Alternative sequenceiVSP_034683724 – 1325Missing in isoform 1. 1 PublicationAdd BLAST602

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF055470 mRNA Translation: AAD15797.1
AB037774 mRNA Translation: BAA92591.1 Different initiation.
AK299293 mRNA Translation: BAG61308.1
BT007117 mRNA Translation: AAP35781.1
AL832911 mRNA Translation: CAH10638.1
AC114490 Genomic DNA No translation available.
AL607089 Genomic DNA No translation available.
BC033903 mRNA Translation: AAH33903.1 Sequence problems.
BC068534 mRNA Translation: AAH68534.1
BC107880 mRNA Translation: AAI07881.1 Sequence problems.
BC117463 mRNA Translation: AAI17464.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS387.2 [O95789-3]

NCBI Reference Sequences

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RefSeqi
NP_009098.3, NM_007167.3 [O95789-3]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.533986
Hs.623978
Hs.729053

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000317538; ENSP00000326695; ENSG00000163867 [O95789-4]
ENST00000357182; ENSP00000349708; ENSG00000163867 [O95789-3]
ENST00000373333; ENSP00000362430; ENSG00000163867 [O95789-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
9204

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:9204

UCSC genome browser

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UCSCi
uc001byh.4 human [O95789-3]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF055470 mRNA Translation: AAD15797.1
AB037774 mRNA Translation: BAA92591.1 Different initiation.
AK299293 mRNA Translation: BAG61308.1
BT007117 mRNA Translation: AAP35781.1
AL832911 mRNA Translation: CAH10638.1
AC114490 Genomic DNA No translation available.
AL607089 Genomic DNA No translation available.
BC033903 mRNA Translation: AAH33903.1 Sequence problems.
BC068534 mRNA Translation: AAH68534.1
BC107880 mRNA Translation: AAI07881.1 Sequence problems.
BC117463 mRNA Translation: AAI17464.1
CCDSiCCDS387.2 [O95789-3]
RefSeqiNP_009098.3, NM_007167.3 [O95789-3]
UniGeneiHs.533986
Hs.623978
Hs.729053

3D structure databases

ProteinModelPortaliO95789
SMRiO95789
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi114638, 51 interactors
IntActiO95789, 6 interactors
STRINGi9606.ENSP00000349708

PTM databases

iPTMnetiO95789
PhosphoSitePlusiO95789

Polymorphism and mutation databases

BioMutaiZMYM6

Proteomic databases

EPDiO95789
jPOSTiO95789
PaxDbiO95789
PeptideAtlasiO95789
PRIDEiO95789
ProteomicsDBi51049
51050 [O95789-1]
51051 [O95789-2]
51052 [O95789-4]
51053 [O95789-5]

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
9204
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000317538; ENSP00000326695; ENSG00000163867 [O95789-4]
ENST00000357182; ENSP00000349708; ENSG00000163867 [O95789-3]
ENST00000373333; ENSP00000362430; ENSG00000163867 [O95789-4]
GeneIDi9204
KEGGihsa:9204
UCSCiuc001byh.4 human [O95789-3]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
9204
EuPathDBiHostDB:ENSG00000163867.16

GeneCards: human genes, protein and diseases

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GeneCardsi
ZMYM6
HGNCiHGNC:13050 ZMYM6
HPAiHPA011004
HPA071865
MIMi613567 gene
neXtProtiNX_O95789
OpenTargetsiENSG00000163867
PharmGKBiPA37628

Human Unidentified Gene-Encoded large proteins database

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HUGEi
Search...

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IE8I Eukaryota
ENOG410XQR6 LUCA
GeneTreeiENSGT00940000159550
ENSGT00940000162386
HOVERGENiHBG058050
InParanoidiO95789
OMAiTIGHRID
OrthoDBi587724at2759
PhylomeDBiO95789
TreeFamiTF336988

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ZMYM6 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
9204

Protein Ontology

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PROi
PR:O95789

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000163867 Expressed in 180 organ(s), highest expression level in adrenal tissue
ExpressionAtlasiO95789 baseline and differential
GenevisibleiO95789 HS

Family and domain databases

InterProiView protein in InterPro
IPR012337 RNaseH-like_sf
IPR026625 TFII-I-rel
IPR011017 TRASH_dom
IPR010507 Znf_MYM
PANTHERiPTHR11697 PTHR11697, 1 hit
PfamiView protein in Pfam
PF06467 zf-FCS, 3 hits
SMARTiView protein in SMART
SM00746 TRASH, 9 hits
SUPFAMiSSF53098 SSF53098, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZMYM6_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O95789
Secondary accession number(s): B4DRJ6
, Q32Q23, Q4G108, Q5SVZ9, Q5SW00, Q69YL4, Q96IY0, Q9NWF1, Q9P2J4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: July 22, 2008
Last modified: February 13, 2019
This is version 140 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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