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UniProtKB - O95670 (VATG2_HUMAN)

Entry version 174 (13 Nov 2019)
Sequence version 1 (01 May 1999)
Previous versions | rss
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Protein

V-type proton ATPase subunit G 2

Gene

ATP6V1G2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processHydrogen ion transport, Ion transport, Transport

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		MetaCyc:HS10685-MONOMER

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-1222556 ROS and RNS production in phagocytes
R-HSA-77387 Insulin receptor recycling
R-HSA-917977 Transferrin endocytosis and recycling
R-HSA-9639288 Amino acids regulate mTORC1
R-HSA-983712 Ion channel transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
V-type proton ATPase subunit G 2
Short name:
V-ATPase subunit G 2
Alternative name(s):
V-ATPase 13 kDa subunit 2
Vacuolar proton pump subunit G 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ATP6V1G2
Synonyms:ATP6G, ATP6G2, NG38
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:862 ATP6V1G2

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		606853 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_O95670

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		534

Open Targets

More...OpenTargetsi		ENSG00000213760

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA25164

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		O95670

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ATP6V1G2

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001929001 – 118V-type proton ATPase subunit G 2Add BLAST118

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		O95670

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		O95670

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O95670

PeptideAtlas

More...PeptideAtlasi		O95670

PRoteomics IDEntifications database

More...PRIDEi		O95670

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		50983 [O95670-1]
6232
62960

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O95670

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O95670

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Brain.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000213760 Expressed in 133 organ(s), highest expression level in cerebellar hemisphere

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		O95670 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O95670 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		CAB004616

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d).

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
Q96A054EBI-348290,EBI-8650380

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		107017, 9 interactors

Protein interaction database and analysis system

More...IntActi		O95670, 9 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000302194

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		O95670

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the V-ATPase G subunit family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1772 Eukaryota
ENOG4111XX0 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000161280

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000186416

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O95670

KEGG Orthology (KO)

More...KOi		K02152

Identification of Orthologs from Complete Genome Data

More...OMAi		HPNYRIT

Database of Orthologous Groups

More...OrthoDBi		1566576at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O95670

TreeFam database of animal gene trees

More...TreeFami		TF313777

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR005124 V-ATPase_G

The PANTHER Classification System

More...PANTHERi		PTHR12713 PTHR12713, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03179 V-ATPase_G, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01147 V_ATP_synt_G, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: O95670-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MASQSQGIQQ LLQAEKRAAE KVADARKRKA RRLKQAKEEA QMEVEQYRRE 
        60         70         80         90        100
REHEFQSKQQ AAMGSQGNLS AEVEQATRRQ VQGMQSSQQR NRERVLAQLL 
       110 
GMVCDVRPQV HPNYRISA
Length:118
Mass (Da):13,604
Last modified:May 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5D46EEE0C8D7657D
GO
Isoform 2 (identifier: O95670-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     35-74: Missing.

Note: No experimental confirmation available.
Show »
Length:78
Mass (Da):8,954
Checksum:iC58F9F6252E8076A
GO
Isoform 3 (identifier: O95670-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-41: Missing.

Note: No experimental confirmation available.
Show »
Length:77
Mass (Da):8,972
Checksum:iA22322E87147DFE7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0Y474H0Y474_HUMAN
V-type proton ATPase subunit G
ATP6V1G2
158Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti52E → D in AA401769 (Ref. 10) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0474111 – 41Missing in isoform 3. 1 PublicationAdd BLAST41
Alternative sequenceiVSP_04590935 – 74Missing in isoform 2. 1 PublicationAdd BLAST40

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
Y14768 Genomic DNA Translation: CAA75073.1
AB063177 Genomic DNA Translation: BAC00863.1
AB102692 Genomic DNA Translation: BAD74058.1
AB097672 Genomic DNA Translation: BAD74057.1
BA000025 Genomic DNA Translation: BAB63399.1
AB088115 Genomic DNA Translation: BAC54952.1
AL662801 Genomic DNA No translation available.
AL662847 Genomic DNA No translation available.
BX001040 Genomic DNA No translation available.
BX248516 Genomic DNA No translation available.
CR753892 Genomic DNA No translation available.
BX927320 Genomic DNA No translation available.
CR753864 Genomic DNA No translation available.
CR753820 Genomic DNA No translation available.
CR942185 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03414.1
CH471081 Genomic DNA Translation: EAX03416.1
AB202112 Genomic DNA Translation: BAE78636.1
AB103621 Genomic DNA Translation: BAF31286.1
BC047791 mRNA No translation available.
BC119726 mRNA Translation: AAI19727.1
BC119727 mRNA Translation: AAI19728.1
AA401769 mRNA No translation available.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS4698.1 [O95670-1]
CCDS4699.1 [O95670-3]
CCDS56413.1 [O95670-2]

NCBI Reference Sequences

More...RefSeqi		NP_001191007.1, NM_001204078.1 [O95670-2]
NP_569730.1, NM_130463.3 [O95670-1]
NP_612139.1, NM_138282.2 [O95670-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000303892; ENSP00000302194; ENSG00000213760 [O95670-1]
ENST00000376151; ENSP00000365321; ENSG00000213760 [O95670-2]
ENST00000383503; ENSP00000372995; ENSG00000206445 [O95670-1]
ENST00000421596; ENSP00000406575; ENSG00000234668 [O95670-2]
ENST00000434217; ENSP00000406668; ENSG00000226850 [O95670-2]
ENST00000441959; ENSP00000395436; ENSG00000227587 [O95670-1]
ENST00000443657; ENSP00000416031; ENSG00000227587 [O95670-2]
ENST00000444088; ENSP00000406389; ENSG00000234920 [O95670-1]
ENST00000447174; ENSP00000403158; ENSG00000230900 [O95670-2]
ENST00000448779; ENSP00000409104; ENSG00000234920 [O95670-2]
ENST00000449748; ENSP00000406372; ENSG00000226850 [O95670-1]
ENST00000452453; ENSP00000402430; ENSG00000206445 [O95670-2]
ENST00000454370; ENSP00000413222; ENSG00000234668 [O95670-1]
ENST00000454889; ENSP00000408670; ENSG00000230900 [O95670-1]
ENST00000483251; ENSP00000419698; ENSG00000213760 [O95670-3]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		534

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:534

UCSC genome browser

More...UCSCi		uc003ntz.4 human [O95670-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y14768 Genomic DNA Translation: CAA75073.1
AB063177 Genomic DNA Translation: BAC00863.1
AB102692 Genomic DNA Translation: BAD74058.1
AB097672 Genomic DNA Translation: BAD74057.1
BA000025 Genomic DNA Translation: BAB63399.1
AB088115 Genomic DNA Translation: BAC54952.1
AL662801 Genomic DNA No translation available.
AL662847 Genomic DNA No translation available.
BX001040 Genomic DNA No translation available.
BX248516 Genomic DNA No translation available.
CR753892 Genomic DNA No translation available.
BX927320 Genomic DNA No translation available.
CR753864 Genomic DNA No translation available.
CR753820 Genomic DNA No translation available.
CR942185 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03414.1
CH471081 Genomic DNA Translation: EAX03416.1
AB202112 Genomic DNA Translation: BAE78636.1
AB103621 Genomic DNA Translation: BAF31286.1
BC047791 mRNA No translation available.
BC119726 mRNA Translation: AAI19727.1
BC119727 mRNA Translation: AAI19728.1
AA401769 mRNA No translation available.
CCDSiCCDS4698.1 [O95670-1]
CCDS4699.1 [O95670-3]
CCDS56413.1 [O95670-2]
RefSeqiNP_001191007.1, NM_001204078.1 [O95670-2]
NP_569730.1, NM_130463.3 [O95670-1]
NP_612139.1, NM_138282.2 [O95670-3]

3D structure databases

SMRiO95670
ModBaseiSearch...

Protein-protein interaction databases

BioGridi107017, 9 interactors
IntActiO95670, 9 interactors
STRINGi9606.ENSP00000302194

PTM databases

iPTMnetiO95670
PhosphoSitePlusiO95670

Polymorphism and mutation databases

BioMutaiATP6V1G2

Proteomic databases

jPOSTiO95670
MassIVEiO95670
PaxDbiO95670
PeptideAtlasiO95670
PRIDEiO95670
ProteomicsDBi50983 [O95670-1]
6232
62960

Genome annotation databases

EnsembliENST00000303892; ENSP00000302194; ENSG00000213760 [O95670-1]
ENST00000376151; ENSP00000365321; ENSG00000213760 [O95670-2]
ENST00000383503; ENSP00000372995; ENSG00000206445 [O95670-1]
ENST00000421596; ENSP00000406575; ENSG00000234668 [O95670-2]
ENST00000434217; ENSP00000406668; ENSG00000226850 [O95670-2]
ENST00000441959; ENSP00000395436; ENSG00000227587 [O95670-1]
ENST00000443657; ENSP00000416031; ENSG00000227587 [O95670-2]
ENST00000444088; ENSP00000406389; ENSG00000234920 [O95670-1]
ENST00000447174; ENSP00000403158; ENSG00000230900 [O95670-2]
ENST00000448779; ENSP00000409104; ENSG00000234920 [O95670-2]
ENST00000449748; ENSP00000406372; ENSG00000226850 [O95670-1]
ENST00000452453; ENSP00000402430; ENSG00000206445 [O95670-2]
ENST00000454370; ENSP00000413222; ENSG00000234668 [O95670-1]
ENST00000454889; ENSP00000408670; ENSG00000230900 [O95670-1]
ENST00000483251; ENSP00000419698; ENSG00000213760 [O95670-3]
GeneIDi534
KEGGihsa:534
UCSCiuc003ntz.4 human [O95670-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		534
DisGeNETi534

GeneCards: human genes, protein and diseases

More...GeneCardsi		ATP6V1G2
HGNCiHGNC:862 ATP6V1G2
HPAiCAB004616
MIMi606853 gene
neXtProtiNX_O95670
OpenTargetsiENSG00000213760
PharmGKBiPA25164

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1772 Eukaryota
ENOG4111XX0 LUCA
GeneTreeiENSGT00940000161280
HOGENOMiHOG000186416
InParanoidiO95670
KOiK02152
OMAiHPNYRIT
OrthoDBi1566576at2759
PhylomeDBiO95670
TreeFamiTF313777

Enzyme and pathway databases

BioCyciMetaCyc:HS10685-MONOMER
ReactomeiR-HSA-1222556 ROS and RNS production in phagocytes
R-HSA-77387 Insulin receptor recycling
R-HSA-917977 Transferrin endocytosis and recycling
R-HSA-9639288 Amino acids regulate mTORC1
R-HSA-983712 Ion channel transport

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		ATP6V1G2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		534
PharosiO95670

Protein Ontology

More...PROi		PR:O95670

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000213760 Expressed in 133 organ(s), highest expression level in cerebellar hemisphere
ExpressionAtlasiO95670 baseline and differential
GenevisibleiO95670 HS

Family and domain databases

InterProiView protein in InterPro
IPR005124 V-ATPase_G
PANTHERiPTHR12713 PTHR12713, 1 hit
PfamiView protein in Pfam
PF03179 V-ATPase_G, 1 hit
TIGRFAMsiTIGR01147 V_ATP_synt_G, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiVATG2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O95670
Secondary accession number(s): B5MEF0
, Q2L6F8, Q5HYU8, Q5RJ63
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: November 13, 2019
This is version 174 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
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